Robust Face Recognition via Low-rank Sparse Representation-based Classification

Face recognition has attracted great interest due to its importance in many real-world applications. In this paper,we present a novel low-rank sparse representation-based classification(LRSRC) method for robust face recognition. Given a set of test samples, LRSRC seeks the lowest-rank and sparsest representation matrix over all training samples. Since low-rank model can reveal the subspace structures of data while sparsity helps to recognize the data class, the obtained test sample representations are both representative and discriminative. Using the representation vector of a test sample, LRSRC classifies the test sample into the class which generates minimal reconstruction error. Experimental results on several face image databases show the effectiveness and robustness of LRSRC in face image recognition.

Tumor microenvironment reprogramming by nanomedicine to enhance the effect of tumor immunotherapy

With the rapid development of the fields of tumor biology and immunology, tumor immunotherapy has been used in clinical practice and has demonstrated significant therapeutic potential, particularly for treating tumors that do not respond to standard treatment options. Despite its advances, immunotherapy still has limitations, such as poor clinical response rates and differences in individual patient responses, largely because tumor tissues have strong immunosuppressive microenvironments. Many tumors have a tumor microenvironment (TME) that is characterized by hypoxia, low pH, and substantial numbers of immunosuppressive cells, and these are the main factors limiting the efficacy of antitumor immunotherapy. The TME is crucial to the occurrence, growth, and metastasis of tumors. Therefore, numerous studies have been devoted to improving the effects of immunotherapy by remodeling the TME. Effective regulation of the TME and reversal of immunosuppressive conditions are effective strategies for improving tumor immunotherapy. The use of multidrug combinations to improve the TME is an efficient way to enhance antitumor immune efficacy. However, the inability to effectively target drugs decreases therapeutic effects and causes toxic side effects. Nanodrug delivery carriers have the advantageous ability to enhance drug bioavailability and improve drug targeting. Importantly, they can also regulate the TME and deliver large or small therapeutic molecules to decrease the inhibitory effect of the TME on immune cells. Therefore, nanomedicine has great potential for reprogramming immunosuppressive microenvironments and represents a new immunotherapeutic strategy. Therefore, this article reviews strategies for improving the TME and summarizes research on synergistic nanomedicine approaches that enhance the efficacy of tumor immunotherapy.

Sinofert's Net Profit down 25% for 2007

Sinofert Holdings Limited(Sinofert,HK:0297)announces the audited annual results of the company and its subsidiaries(the Group)for 2007.The Group’s turnover amounted to HK＄29.437 billion,up 39.34% year-on-year.The net profit amounted to HK＄663 million,a year-on-year decrease of 25.99%.Sale volume amounted to 15.16 million tons,a year-on-year increase of 20.55%,ac-counting for 17% market shares in China Mainland in terms of pure nutrient,increased by 3.5 percentage points year-on-year.Of which,sale imported fertilizer amounted to 5.95 million tons,an increase of 12.26% year-on-year and accounting for 39% of total sale volume;sale volume of domestic fertilizer amounted to 8.61 million tons,an increase of 35.26% year-on-year and accounting for 57% of total sale volume.The sales volume of domestic fertilizer in total sales volume was up 6 percentage points,representing a

新型典范:REPR 7.62MM多用途精确步枪

当今自动步枪正显示一种新的发展态势,即向多用途、高精度方向发展,新近上市的"快速交战精确步枪(REPR)"正是这样一种能适应各种任务环境的步枪,该枪的高可靠性和高精度在军方和执法机构中将拥有广泛的应用前景. REPR步枪采用7.62×51mm北约制式口径,可快速更换4种长度不同的枪管,包括适于城市狭窄作战环境的305mm枪管、兼顾精度与使用便捷性的406mm枪管、专供精确射击的457mm 比赛级枪管以及专业级的508mm狙击枪管.该枪为自动步枪,主要面向军用,在美国属管制级枪械,民事或执法机构需采购该枪,要得到美国酒精、烟草与火器管理局(ATF)的审核批准.