The research and development of penicillin started with dificulty before 1949 and achieved certain results.In 1951,after the founding of the People’ s Republic of China,Zhang Weishen,as the only Chinese scientist who...The research and development of penicillin started with dificulty before 1949 and achieved certain results.In 1951,after the founding of the People’ s Republic of China,Zhang Weishen,as the only Chinese scientist who had been trained and worked in a penicillin research and development center in the United States for many years,overcame many difficulties and returned to China.In 1953,with the efforts of Zhang Weishen and his colleagues,China realized the industrialized production of penicillin,alleviating the urgent needs of the masses.Antibiotics has also become the first discipline to achieve major scientific and technological achievements after the founding of the New China.In the mid-1950s,the technical breakthrough in the localization of lactose substitutes marked the localization of the raw materials of the penicillin-producing culture medium,which paved the way for the industrialized production of penicillin with Chinese characteristics.Antibiotics have become one of the most widely used and affordable drugs for hundreds of millions of patients in China,and China has since ended the humiliating history of the "Sick Man of East Asia".展开更多
为了解当前国际上关于土壤中抗生素研究的现状与趋势,以Web of Science核心数据库为基础,借助引文分析软件CiteSpace对1941—2018年的相关研究成果进行了计量学和可视化分析,绘制知识图谱,揭示土壤中抗生素研究的发展和知识结构。结果表...为了解当前国际上关于土壤中抗生素研究的现状与趋势,以Web of Science核心数据库为基础,借助引文分析软件CiteSpace对1941—2018年的相关研究成果进行了计量学和可视化分析,绘制知识图谱,揭示土壤中抗生素研究的发展和知识结构。结果表明:土壤中抗生素的研究主要经历了起步探索期(1941—1989年)、平稳发展期(1990—2002年)和快速增长期(2003—2018年)三个阶段;该研究方向受到多学科、多领域的广泛关注,跨学科交叉研究将会是后续研究的主要突破点;当前已形成联系紧密的土壤中抗生素研究核心作者群,且中国科学院发文量最多,而美国和德国的研究成果影响力最大;研究热点主要侧重于土壤中抗生素的种类及残留水平分析、环境行为模拟、生态毒性及抗性基因影响与控制等主题。研究表明,土壤中抗生素研究仍存在一些亟需解决的问题,建议结合创新性方法(技术)深入开展土壤中抗生素的研究,切实解决抗生素滥用导致的一系列生态风险和人体健康问题。展开更多
文摘The research and development of penicillin started with dificulty before 1949 and achieved certain results.In 1951,after the founding of the People’ s Republic of China,Zhang Weishen,as the only Chinese scientist who had been trained and worked in a penicillin research and development center in the United States for many years,overcame many difficulties and returned to China.In 1953,with the efforts of Zhang Weishen and his colleagues,China realized the industrialized production of penicillin,alleviating the urgent needs of the masses.Antibiotics has also become the first discipline to achieve major scientific and technological achievements after the founding of the New China.In the mid-1950s,the technical breakthrough in the localization of lactose substitutes marked the localization of the raw materials of the penicillin-producing culture medium,which paved the way for the industrialized production of penicillin with Chinese characteristics.Antibiotics have become one of the most widely used and affordable drugs for hundreds of millions of patients in China,and China has since ended the humiliating history of the "Sick Man of East Asia".
文摘为了解当前国际上关于土壤中抗生素研究的现状与趋势,以Web of Science核心数据库为基础,借助引文分析软件CiteSpace对1941—2018年的相关研究成果进行了计量学和可视化分析,绘制知识图谱,揭示土壤中抗生素研究的发展和知识结构。结果表明:土壤中抗生素的研究主要经历了起步探索期(1941—1989年)、平稳发展期(1990—2002年)和快速增长期(2003—2018年)三个阶段;该研究方向受到多学科、多领域的广泛关注,跨学科交叉研究将会是后续研究的主要突破点;当前已形成联系紧密的土壤中抗生素研究核心作者群,且中国科学院发文量最多,而美国和德国的研究成果影响力最大;研究热点主要侧重于土壤中抗生素的种类及残留水平分析、环境行为模拟、生态毒性及抗性基因影响与控制等主题。研究表明,土壤中抗生素研究仍存在一些亟需解决的问题,建议结合创新性方法(技术)深入开展土壤中抗生素的研究,切实解决抗生素滥用导致的一系列生态风险和人体健康问题。
