Curriculum Reform Practices in “Cosmetic Product Formulation Design and Preparation Technology” Under the Perspective of Integration of Industry, Education, and Research

With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Technology”serves as the foundation for cultivating students’abilities in cosmetic development and preparation.To foster high-quality skilled talents capable of adapting to the rapid growth of color cosmetics and to better promote the deep integration of scientific and technological industries with curriculum teaching,the teacher team embarked on active explorations and practical teaching research for curriculum teaching reform from four dimensions:strengthening top-level design,enriching teaching content,optimizing teaching design,and reforming assessment methods.These efforts have enhanced students’comprehensive vocational qualities and innovative consciousness,contributing to the teaching reform in higher vocational colleges under the integration of industry,education,and research.

Glucocorticoids-based prodrug design:Current strategies and research progress

Attributing to their broad pharmacological effects encompassing anti-inflammation,antitoxin,and immunosuppression,glucocorticoids(GCs)are extensively utilized in the clinic for the treatment of diverse diseases such as lupus erythematosus,nephritis,arthritis,ulcerative colitis,asthma,keratitis,macular edema,and leukemia.However,longterm use often causes undesirable side effects,including metabolic disorders-induced Cushing's syndrome(buffalo back,full moon face,hyperglycemia,etc.),osteoporosis,aggravated infection,psychosis,glaucoma,and cataract.These notorious side effects seriously compromise patients'quality of life,especially in patients with chronic diseases.Therefore,glucocorticoid-based advanced drug delivery systems for reducing adverse effects have received extensive attention.Among them,prodrugs have the advantages of low investment,low risk,and high success rate,making them a promising strategy.In this review,we propose the strategies for the design and summarize current research progress of glucocorticoid-based prodrugs in recent decades,including polymer-based prodrugs,dendrimer-based prodrugs,antibody-drug conjugates,peptide-drug conjugates,carbohydrate-based prodrugs,aliphatic acid-based prodrugs and so on.Besides,we also raise issues that need to be focused on during the development of glucocorticoid-based prodrugs.This review is expected to be helpful for the research and development of novel GCs and prodrugs.

Practice and Exploration of Ideological and Political Teaching in Landscape Design Courses for Environmental Design Majors

To implement the fundamental goal of moral education,based on the teaching practice of landscape design courses,we explore how to integrate value shaping,knowledge transfer,and skill cultivation in the teaching links of landscape design courses in environmental design majors,such as selecting design topics,assigning tasks,researching projects,designing works,designing explanations,and defense.

A Win-Win Undergraduate Graduation Design Model for Students, Teachers, and Training Platforms

Undergraduate graduation design is an important link in the process of undergraduate training,and university platforms have invested a lot of manpower and material resources for this purpose.However,while carrying out student training,it has gradually become the consensus of most university platforms to achieve a win-win situation for teachers and training platforms in order to achieve optimization of resource allocation and motivation of student training.After discussion and practice,this paper proposes a set of undergraduate graduation design training concepts and training modes with a win-win situation for students,teachers,and training platforms.

Research on the Course of Principles of Concrete Structure Design

Nowadays,education and teaching have become a hot topic,and teaching in colleges and universities is facing a brand-new development direction.Principles of Concrete Structure Design,as one of the main courses,transmits professional knowledge for students,enhances the students’professional ability,and further carries out in-depth research on the course to bring a better teaching effect for students.The article mainly focuses on the research of the principles of concrete structure design course,conducts an analysis of the teaching characteristics of the principles of concrete structure design course,and reasonably sets the teaching content from the optimization of the course teaching objectives;innovative course teaching methods can deepen the effect of knowledge understanding;reform of experimental practice teaching can lay down the effect of the internalization of knowledge,etc.The in-depth description and discussion of the relevant aspects of the research aim to provide guidelines for related research.

Neutronic design investigation of a liquid injection-based second shutdown system for a typical research reactor using MCNPX

Safety systems, built on state-of-the-art technology, are essential for achieving acceptable levels of plant safety to minimize hazards to the reactor and the general public. The second shutdown system(SSS) as an engineered safety feature and a part of the reactor protection system(RPS) is a means for rapidly shutting down a nuclear reactor, keeping it in a subcritical state and serving as a backup to the first shutdown system(FSS). In this research, one SSS with two types of optimum chamber designs is proposed that take into account the main current characteristic features of the Tehran research reactor with improvements over earlier designs. They are based on a liquid neutron absorber injection that is preferably different, diverse, and independent from the FSS based on the rod drop mechanism. The major design characteristics of this SSS with two different chambers were investigated using MCNPX 2.6.0 code. The performed calculations showed that the designed SSS is a reliable shutdown system, assuring an appropriate shutdown margin and injection time, with no significant effects on the effective delayed neutron fraction while causing minimal variations to the core structure. Further, the reasonable financial cost and the prolongation of the operation cycle are additional advantages of this design.

Review of Design of Process Parameters for Squeeze Casting

Squeeze casting(SC)is an advanced net manufacturing process with many advantages for which the quality and properties of the manufactured parts depend strongly on the process parameters.Unfortunately,a universal efficient method for the determination of optimal process parameters is still unavailable.In view of the shortcomings and development needs of the current research methods for the setting of SC process parameters,by consulting and analyzing the recent research literature on SC process parameters and using the CiteSpace literature analysis software,manual reading and statistical analysis,the current state and characteristics of the research methods used for the determination of SC process parameters are summarized.The literature data show that the number of pub-lications in the literature related to the design of SC process parameters generally trends upward albeit with signifi-cant fluctuations.Analysis of the research focus shows that both“mechanical properties”and“microstructure”are the two main subjects in the studies of SC process parameters.With regard to materials,aluminum alloys have been extensively studied.Five methods have been used to obtain SC process parameters:Physical experiments,numeri-cal simulation,modeling optimization,formula calculation,and the use of empirical values.Physical experiments are the main research methods.The main methods for designing SC process parameters are divided into three categories:Fully experimental methods,optimization methods that involve modeling based on experimental data,and theoreti-cal calculation methods that involve establishing an analytical formula.The research characteristics and shortcomings of each method were analyzed.Numerical simulations and model-based optimization have become the new required methods.Considering the development needs and data-driven trends of the SC process,suggestions for the develop-ment of SC process parameter research have been proposed.

Synoptic review on existing and potential sources for bias in dental research methodology with methods on their prevention and remedies

The results of years of dental study serve as the foundation for the practise of medicine and,for that matter,dentistry.Doctors may have their own preferences for techniques and materials,but whether directly or indirectly,their decisions are influenced by systematic reviews and meta-analyses.However,due to poorly conducted or presented research,this very basic foundation may not be reliable.Bias in research is one of several factors that might make study results or research itself unreliable.Bias can be introduced into research at many stages,deliberately or unknowingly.Bias can appear at any point during the research process,even before the study itself begins.There are many biases in research,but some of them are more relevant to dentistry research than others.Because it is said that“eyes see what the mind knows”,it is essential to have a complete understanding of the different types of bias,how and when they get entrenched,and what steps may be taken to prevent or lessen them if they do occur.This comprehensive summary of bias in dentistry research is provided by this synoptic review.The goal is to identify gaps and measures that have been taken-or that should have been taken-by providing both descriptive and evaluative summaries,as well as examples from the literature,when needed.

Current situation and development trend of design methods for subgrade structure of high speed railways

Purpose–This method will become a new development trend in subgrade structure design for high speed railways.Design/methodology/approach–This paper summarizes the structural types and design methods of subgrade bed for high speed railways in China,Japan,France,Germany,the United States and other countries based on the study and analysis of existing literature and combined with the research results and practices of high speed railway subgrade engineering at home and abroad.Findings–It is found that in foreign countries,the layered reinforced structure is generally adopted for the subgrade bed of high speed railways,and the unified double-layer or multi-layer structure is adopted for the surface layer of subgrade bed,while the simple structure is adopted in China;in foreign countries,different inspection parameters are adopted to evaluate the compaction state of fillers according to their respective understanding and practice,while in China,compaction coefficient,subsoil coefficient and dynamic deformation modulus are adopted for such evaluation;in foreign countries,the subgrade top deformation control method,the subgrade bottom deformation control method,the subsurface fill strength control method are mainly adopted in subgrade bed structure design of high speed railways,while in China,dynamic deformation control of subgrade surface and dynamic strain control of subgrade bed bottom layer is adopted in the design.However,the cumulative deformation of subgrade caused by train cyclic vibration load is not considered in the existing design methods.Originality/value–This paper introduces a new subgrade structure design method based on whole-process dynamics analysis that meets subgrade functional requirements and is established on the basis of the existing research at home and abroad on prediction methods for cumulative deformation of subgrade soil.

An Experimental Study on the Effectiveness of Individualized Online Intervention for Mental Health Literacy of Community Residents

Background:Understanding how to improve mental health literacy is conducive to maintaining and promoting individuals’mental health and well-being.However,to date,interventions for mental health literacy primarily depend on traditional education and contact interventions,which have limitations with regard to pertinence and individualization.Artificial intelligence(AI)and big data technology have influenced mental health services to be more intellectual and digital,and they also provide greater technical convenience for individualized interventions for promoting mental health literacy.However,there is relatively little research on the effectiveness of individualized online intervention for mental health literacy in the literature.This study aims to fill this void.To verify whether individualized online intervention can improve the level of mental health literacy.Methods:We conducted a pretest–post-test control experiment.The participants were recruited from a large community located in central China.A total of 152 participants completed the research.We use mixed linear model estimation and paired t-tests to analyze the data.Results:Individualized online intervention can effectively improve the mental health literacy level of participants.Specifically,we found that compared with the control group,the mental health literacy in the experimental group was significantly improved after receiving individualized online intervention.Likewise,the mental health literacy of the control group has also improved after receiving individualized online intervention.In addition,we compared the mental health literacy level of the experimental group at Time 3 to those at Time 2 and found that the mental health literacy level at Time 3 had not decreased one month later.This shows that individualized online intervention was not only momentarily effective,but also had long-term efficacy.Conclusion:This study illustrates that the individualized online intervention has both great momentary and long-term effectiveness in improving community residents’mental health literacy.

Conceptual Proposal of a Facility Design for Accommodating Minipigs for Pharmaceutical and Radiopharmaceutical Research

The use of Animal House Facilities of IPEN-CNEN/SP （Nuclear and Energetic Research Institute-National Nuclear Energy Commission/SP, Brazil） has provided rats and mice with controlled sanitary quality for research and quality control in the production of radiopharmaceuticals lots, produced at IPEN, following rules of CONCEA-Brazilian National Council for Animal Experimentation Control and approved in CEUA （Ethics Committee on the Use of Animals）, before they are sent to hospitals and clinics spread out in Brazil, for use in nuclear medicine. The production and the supply of high quality laboratory animals have fundamental importance for the accomplishment of vanguard scientific research, with reproducibility and universality. The quality of those animals depends, largely, on the available facilities for their production and lodging, to assure the demanded sanitary control and animal＇s welfare, in agreement with the ethical principles that control the activity. Therefore, the facilities design is of vital importance so that the mentioned requirements can be reached. Nevertheless, pigs and miniature pigs have gained importance as large animal models in medicine. With their size, organ capacity, and physiology resembling in several aspects that of humans, pigs are well suited for preclinical experiments and long-term safety studies. Minipigs will be used for preclinical testing of radiopharmaceuticals and assays radioactive materials for cardiac tests. This paper describes the premises and preliminary activities that have been performed at IPEN for the design of new Animal House Facilities dedicated to keeping minipigs taking into account fundamental aspects such as： animal＇s welfare, sanitation, genetic, in agreement with the ethical principles that control the activity and environmental concerns.

Research on the Design of the Innovative Teaching Platform for College English Linguistics Based on Network Technologies

As a compulsory course for English majors in colleges and universities, English linguistics is of great significance to English majors in colleges and universities. However, as the English linguistics curriculum itself belongs to theoretical teaching, the teaching process requires the two-way interaction between teachers and students, so the teaching effect is not good. College English linguistics takes the cultivation of students' comprehensive abilities to use English as the premise, and emphasizes the cultivation of students' listening and speaking abilities to help students transmit the accurate written and oral information in the process of the social work and communication, thus improving students' English levels and preparing for their future international communication.

Analysis and research on the demands of the fashion emotional design for the modem professional women

Clothing is a kind of the clothing design activity based on the emotional factors and the concrete understandings. Clothing is not only a kind of the life necessities, but also the interpretation and expression of our own temperament and personalities. Of course, the best effects of the entire costume design activity can be achieved only when the costume itself is matched with the person＇s identity. In this paper, from the analysis of the influence and the relationship between the clothing emotion and the fashion design activities, combined with the analysis of the specific characteristics of the groups of the modern occupational females, the author explores the modem women＇s specific needs in the clothing emotional design, and explores the specific ideas of the modern professional women＇s clothing emotional design.

从Design Research思潮看我国艺术设计工作室教学模式的改革

艺术设计教学改革一直是困扰我国艺术设计教育的一个重大课题,本文将国内当前各大院校流行的艺术设计工作室教学改革模式与欧美发达国家的艺术设计Design Research思潮进行对比,结合美国著名大学艺术设计研究生的实际设计课题,剖析中西方关于艺术设计教育教学模式中存在的较深层次的差异,目的是为完善我国设计工作室教学模式和整个艺术设计教育找出新的办法。

设计研究发展与热点分析——以Design Studies期刊于2007—2021年发表的论文为例

为更好地了解设计研究领域的发展趋势,掌握设计研究过程的前沿热点,以Web of Science数据库收录的核心期刊Design Studies于2007—2021年发表的论文为例,利用文献计量法和VOSviewer可视化工具对发文国家、文献共被引、研究机构、高产作者、高频关键词等方面进行分析。结果表明:设计研究领域发展脉络清晰,英国、美国占据主导地位。近年来的研究热点聚焦于设计实践方法、设计交互理念、设计成果评估与设计解决方案创新等方面;而设计方法开发、设计灵感来源及未来服务设计等主题已成为该领域的研究前沿。结合当前国内设计研究领域发展现状,中国学者需适当兼顾国际期刊发表规律,积极促进与设计过程相关的理论开发与应用,在该领域发出更多“中国声音”。

An Innovative Soft Design Science Methodology for Improving Development of a Secure Information System in Tanzania Using Multi-Layered Approach

This paper presents an innovative Soft Design Science Methodology for improving information systems security using multi-layered security approach. The study applied Soft Design Science Methodology to address the problematic situation on how information systems security can be improved. In addition, Soft Design Science Methodology was compounded with mixed research methodology. This holistic approach helped for research methodology triangulation. The study assessed security requirements and developed a framework for improving information systems security. The study carried out maturity level assessment to determine security status quo in the education sector in Tanzania. The study identified security requirements gap (IT security controls, IT security measures) using ISO/IEC 21827: Systems Security Engineering-Capability Maturity Model (SSE-CMM) with a rating scale of 0 - 5. The results of this study show that maturity level across security domain is 0.44 out of 5. The finding shows that the implementation of IT security controls and security measures for ensuring security goals are lacking or conducted in ad-hoc. Thus, for improving the security of information systems, organisations should implement security controls and security measures in each security domain (multi-layer security). This research provides a framework for enhancing information systems security during capturing, processing, storage and transmission of information. This research has several practical contributions. Firstly, it contributes to the body of knowledge of information systems security by providing a set of security requirements for ensuring information systems security. Secondly, it contributes empirical evidence on how information systems security can be improved. Thirdly, it contributes on the applicability of Soft Design Science Methodology on addressing the problematic situation in information systems security. The research findings can be used by decision makers and lawmakers to improve existing cyber security laws, and enact laws for data privacy and sharing of open data.

Advances in machine learning-and artificial intelligence-assisted material design of steels

With the rapid development of artificial intelligence technology and increasing material data,machine learning-and artificial intelligence-assisted design of high-performance steel materials is becoming a mainstream paradigm in materials science.Machine learning methods,based on an interdisciplinary discipline between computer science,statistics and material science,are good at discovering correlations between numerous data points.Compared with the traditional physical modeling method in material science,the main advantage of machine learning is that it overcomes the complex physical mechanisms of the material itself and provides a new perspective for the research and development of novel materials.This review starts with data preprocessing and the introduction of different machine learning models,including algorithm selection and model evaluation.Then,some successful cases of applying machine learning methods in the field of steel research are reviewed based on the main theme of optimizing composition,structure,processing,and performance.The application of machine learning methods to the performance-oriented inverse design of material composition and detection of steel defects is also reviewed.Finally,the applicability and limitations of machine learning in the material field are summarized,and future directions and prospects are discussed.

An Research on the Model Design of the Academic Education's Credit Transfer in the Open University

Based on the analyses of the credit bank both at home and abroad, explore the effective way to construct the credit transfer model, find out the main problems in the process of transferring, design a much better model, formulate a new standard for credit transfer and carry out the research on the model design of the academic education's credit transfer in the open university.

Research and Design of Reconfigurable Matrix Multiplication over Finite Field in VLIW Processor

Matrix multiplication plays a pivotal role in the symmetric cipher algorithms, but it is one of the most complex and time consuming units, its performance directly affects the efficiency of cipher algorithms. Combined with the characteristics of VLIW processor and matrix multiplication of symmetric cipher algorithms, this paper extracted the reconfigurable elements and analyzed the principle of matrix multiplication, then designed the reconfigurable architecture of matrix multiplication of VLIW processor further, at last we put forward single instructions for matrix multiplication between 4×1 and 4×4 matrix or two 4×4 matrix over GF(2~8), through the instructions extension, the instructions could support larger dimension operations. The experiment shows that the instructions we designed supports different dimensions matrix multiplication and improves the processing speed of multiplication greatly.

Caregiving in Alzheimer’s Disease: Research Designs &Considerations

Alzheimer’s disease and related dementias have made a considerable impact on society, and can take a significant toll on familial caregivers. Recent successful caregiving interventions suggest a promising future, though informed research design, a priori, is paramount in ensuring quality results that the Government and public may use to make informed policy and personal healthcare decisions. Research designs including basic science, randomized controlled trials (RCTs), qualitative, and quasi-experimental designs serve as the primary basis for discussion with literary examples and caveats.