While conventionally perceived as major components of cellular membranes and lipid droplets （LDs）, lipids have now emerged as key players with distinctive roles involving in a wide range of biological processes such...While conventionally perceived as major components of cellular membranes and lipid droplets （LDs）, lipids have now emerged as key players with distinctive roles involving in a wide range of biological processes such as signaling events, trafficking, and compartmentalization of macromolecules. One of the key concerns in lipid research is its homeostasis, which is fundamental to health maintenance of cells, living organisms and human beings. It is evident now that deregulated lipid metabolism plays very important roles in many human diseases such as type 2 diabetes, cardiovascular diseases, Alzheimer＇s disease （AD）, Parkinson＇s disease, cancer and infectious diseases （Lam and Shui, 2013）.展开更多
文摘While conventionally perceived as major components of cellular membranes and lipid droplets （LDs）, lipids have now emerged as key players with distinctive roles involving in a wide range of biological processes such as signaling events, trafficking, and compartmentalization of macromolecules. One of the key concerns in lipid research is its homeostasis, which is fundamental to health maintenance of cells, living organisms and human beings. It is evident now that deregulated lipid metabolism plays very important roles in many human diseases such as type 2 diabetes, cardiovascular diseases, Alzheimer＇s disease （AD）, Parkinson＇s disease, cancer and infectious diseases （Lam and Shui, 2013）.
