Research Progress and Prospects of Total Factor Productivity in the Construction Industry

The high-quality development of the construction industry fundamentally stems from the significant improvement of total factor productivity.Therefore,it is of crucial significance for promoting the development of the construction industry to a higher level by scientifically and accurately measuring the total factor productivity of the construction industry and deeply analyzing the influencing factors behind it.Based on a comprehensive consideration of research methods and influencing factors,this paper systematically reviews the existing relevant literature on total factor productivity in the construction industry,aiming to reveal the current research development trend in this field and point out potential problems.This effort aims to provide a solid theoretical foundation and valuable reference for further in-depth research,and jointly promote the continuous progress and development of total factor productivity research in the construction industry.

Glucocorticoids-based prodrug design:Current strategies and research progress

Attributing to their broad pharmacological effects encompassing anti-inflammation,antitoxin,and immunosuppression,glucocorticoids(GCs)are extensively utilized in the clinic for the treatment of diverse diseases such as lupus erythematosus,nephritis,arthritis,ulcerative colitis,asthma,keratitis,macular edema,and leukemia.However,longterm use often causes undesirable side effects,including metabolic disorders-induced Cushing's syndrome(buffalo back,full moon face,hyperglycemia,etc.),osteoporosis,aggravated infection,psychosis,glaucoma,and cataract.These notorious side effects seriously compromise patients'quality of life,especially in patients with chronic diseases.Therefore,glucocorticoid-based advanced drug delivery systems for reducing adverse effects have received extensive attention.Among them,prodrugs have the advantages of low investment,low risk,and high success rate,making them a promising strategy.In this review,we propose the strategies for the design and summarize current research progress of glucocorticoid-based prodrugs in recent decades,including polymer-based prodrugs,dendrimer-based prodrugs,antibody-drug conjugates,peptide-drug conjugates,carbohydrate-based prodrugs,aliphatic acid-based prodrugs and so on.Besides,we also raise issues that need to be focused on during the development of glucocorticoid-based prodrugs.This review is expected to be helpful for the research and development of novel GCs and prodrugs.

Research progress on dynamic monitoring of ctDNA and drug resistance related concomitant mutations in non-small cell lung cancer

Owing to significantly prolonged survival,targeted therapy has become standardized recommendation for advanced non-small cell lung cancer patients with mutated driver genes.However,the genetic status of lung cancer patients is dynamic.By dynamically monitoring the evolution of genes status,differential genes and concomitant genes related to progressive disease could be confirmed early,so as to achieve a more accurate and comprehensive insight of the whole process management of targeted therapy for lung cancer patients.Under the guidance of accurate genetic testing results,it is helpful to provide patients with more effective,long-term,and stable individualized targeted therapy.

Research Progress on Pathogens of Main Diseases of Dictyophora rubrovalvata and Their Occurrence

Dictyophora rubrovalvata is an edible fungus with rich nutritional value.It contains various nutrients and bioactive components,and has immunomodulation,anti-tumor,anti-oxidation,anti-fatigue,anti-aging,anti-inflammation and alcoholic hepatitis-protection effects.With the continuous expansion of planting area of Dictyophora,the disease problem has become a major problem affecting the development of Dictyophora industry.In this paper,the pathogens,harmful symptoms and causes of main diseases in Dictyophora were summarized,so as to provide reference for comprehensive control of Dictyophora diseases and promote the high-quality development of Dictyophora industry.

Clinical Application and Research Progress of Common Event-Related Potentials

This paper review focuses on the diagnostic application and clinical efficacy correlation of event-related potentials,such as P300,MMN,CNV and N400,in patients with depression,and provides a reliable theoretical basis for the diagnosis and prognosis of later depression.

Research Progress of Dai and Western Medicine in the Treatment of Gouty Arthritis

This paper reviews the pathogenesis,diagnostic criteria,and treatment means of gouty arthritis from the perspectives of Western medicine and Dai medicine in order to provide a reference for clinical medication.

Research Progress on Modern Biological Mechanism of Chinese Medicine in Prevention and Treatment of Gouty Nephropathy

Chinese medicine prevention and treatment of gouty nephropathy often uses single drugs and compound formulae to regulate uric acid,which has the effect of lowering uric acid,protecting the kidneys and improving clinical symptoms.In conclusion,the mechanism of action of Chinese medicine against gouty nephropathy mainly involves oxidative stress,inflammatory response,etc.,with a view to providing new ideas and methods for the prevention and treatment of gouty nephropathy by Chinese medicine.

Progress and prospect of mid-deep geothermal reinjection technology

Mid-deep geothermal reinjection technology is crucial for the sustainable development of geothermal resources,which has garnered significant attention and rapid growth in recent years.Currently,various geothermal reinjection technologies lag behind,lacking effective integration to address issues like low reinjection rates and thermal breakthrough.This paper reviews the basic principles and development history of mid-deep geothermal reinjection technology,focusing on various technical methods used in the process and analyzing their applicability,advantages,and disadvantages under different geological conditions.It highlights the unique challenges posed by deep geothermal resources,including high temperature,high pressure,high stress,chemical corrosion,and complex geological structures.Additionally,it addresses challenges in equipment selection and durability,system stability and operation safety,environmental impact,and sustainable development.Finally,the paper explores future directions for mid-deep geothermal reinjection technology,highlighting key areas for further research and potential pathways for technological innovation.This comprehensive analysis aims to accelerate the advancement of geothermal reinjection technology,offering essential guidance for the efficient reinjection and sustainable development of geothermal resources.

Research Progress of Additive Manufacturing Technology in Energetic Material Field at Home and Abroad

As a subversive manufacturing technology, additive manufacturing technology has many technical advantages such as high freedom of design and not limited by complex structure of parts. The application of additive manufacturing technology to the charge molding of energetic materials will subvert the traditional manufacturing concept of energetic materials, realize the advanced charge design concept, shorten the research and development time of weapons and equipment, and improve the comprehensive performance of weapons and equipment, which is of great significance for the rapid development of high-tech weapons and equipment. This paper analyzes the research progress of additive manufacturing technology in the field of energetic materials at home and abroad and puts forward some suggestions for future research of this technology. .

Research Progress on the Anti-Atherosclerotic Effect and Mechanism of Tetramethylpyrazine

Atherosclerosis is a chronic vascular disease and the most common pathological change of cardiovascular disease.Its pathogenesis is closely related to inflammation,oxidative stress,lipid accumulation,and calcinosis.Tetramethylpyrazine plays an anti-atherosclerotic role by regulating lipid metabolism,inhibiting foam cell formation,alleviating inflammation,inhibiting vascular calcification and abnormal platelet activation,and has a cardiovascular protective effect.Therefore,this paper summarized the research progress of the anti-atherosclerosis effect and mechanism of tetramethylpyrazine.

Progress of Research on the Effect of Dietary Care on Patients with Gastritis and Gastric Ulcers

Gastritis gastric ulcer is a common disease of the digestive system,which has a serious impact on the quality of life and health of affected individuals.Dietary care is one of the important measures to treat and prevent gastritis gastric ulcers.This paper reviews the research progress on the impact of dietary care on patients with gastritis and gastric ulcers,including dietary behavioral intervention,dietary habit cultivation,dietary hygiene education,and nutritional support.Studies have shown that rational dietary care was able to improve the clinical symptoms of patients,regulate the intestinal microbial community,anti-inflammatory,antioxidant,and other pathways to improve the pathophysiological state of patients with gastritis and gastric ulcer and prevent recurrence.Therefore,dietary care is of great significance to patients with gastritis and gastric ulcers.

Research Progress on the Influencing Factors and Preventive Interventions of Iron Deficiency

Iron is an important element that maintains the normal operation of the body.It not only participates in various physiological reactions as a component of various enzymes,but also is an indispensable component in the synthesis of hemoglobin(Hb)and myoglobin,which transport oxygen.About two-thirds of the iron in the body is stored in the Hb of red blood cells,with a small amount present in myoglobin in muscle tissue and enzymes required for various metabolic reactions.The remaining amount is mostly in the form of ferritin as a mobilized iron reserve.When dietary iron intake is limited and the stored iron in the body is insufficient or depleted,iron deficiency occurs.Iron deficiency can be further divided into three stages based on their severity,namely iron deficiency(ID),iron deficiency erythropoiesis(IDE),and iron deficiency anemia(IDA).This study aims to explore the prevalence,diagnosis and differentiation,influencing factors,and preventive interventions of iron deficiency.

Research Progress on the Prevention of Premature Infant Lung Injury and Neonatal Respiratory Support

In the past 40 years,advances in neonatal intensive care unit(NICU)technology have enabled premature infants with lower birth weight and younger gestational age to survive.But with it comes an increase in the incidence of long-term respiratory dysfunction,mainly in the form of bronchopulmonary dysplasia(BPD).Preventing lung injury is crucial for preventing BPD and improving the long-term prognosis of premature infants.Therefore,how to avoid ventilator-associated lung injury has become a focus of clinical and scientific research in premature infants in recent years.This article will elaborate on the susceptibility and pathophysiology of premature infant lung injury,ventilation strategies for preventing lung injury,and new advances in neonatal respiratory support.

Research Progress of Ultrasound Radiomics in The Diagnosis and Treatment of Breast Cancer

With the advancement of medical research in recent years and the frequent occurrence of different types of cancer, breast cancer has gradually attracted the public’s attention. The incidence of breast cancer is rising, mainly affecting women with a high mortality rate. According to the clinical treatment effect, early diagnosis and early treatment can effectively control the mortality of breast cancer and improve patient’s quality of life. Ultrasound radiomics is an emerging field that can extract quantitative high-dimensional data from ultrasound images. Recently, ultrasound radiomics has been widely used in the clinical treatment of breast cancer. This paper analyzed the research progress of ultrasound radiomics in the diagnosis and treatment of breast cancer.

Research Progress on Combined Chinese and Western Medicine Treatment of Mycoplasma pneumoniae Pneumonia in Children

With the continuous development of medical technology,combined treatment of Chinese and Western medicine has gradually become a research hotspot.As a common disease in pediatrics,the treatment of Mycoplasma pneumoniae pneumonia(MPP)in children is also being explored and improved.This article summarizes the research progress of combined Chinese and Western medicine treatment of MPP in children in recent years,aiming to provide a useful reference for the combined treatment of MPP in children.The article firstly introduces the etiology and pathogenesis of MPP in children,thereafter briefly introduces the Western anti-infective treatment and traditional Chinese medicine(TCM)diagnosis and treatment of MPP in children,and lastly introduces the methods of combined treatment of TCM and Western medicine in detail.The article points out that the combination of Chinese and Western medicine can give full play to the overall regulation of Chinese medicine and the precise treatment advantages of Western medicine,improve the therapeutic effect,reduce the use of antibiotics,and lower the recurrence rate of the disease,which is worthy of further research and promotion.

Research Progress on the Depression Status and Nursing Intervention in Patients after Percutaneous Coronary Intervention

Percutaneous coronary intervention(PCI)is an effective treatment method for myocardial ischemic necrosis.Postoperative depression caused by PCI stress will adversely affect the prognosis of patients.This article reviews the current status and influencing factors of postoperative depression after PCI and summarizes the corresponding nursing interventions,to provide a literature reference to implement effective nursing interventions for depressed patients after clinical PCI.

Research Progress and Application Prospect of Chengyin Decoction (Granule)

Research and development of Chengyin detoxification prescription are taken as research objects. Starting from preparation research and development, clinical research, urgency and market demand, and significance for industrial development, the relevant research of Chengyin detoxification prescription is systematically reviewed, and the application prospect of the ethnic medicine preparations is looked forward to.

Research Progress and Prospects for the Evolution Process and Treatment Technology of Urban Black and Smelly Water

Water is an important material resource for human survival,and with the increasing development of society,the amount of urban industrial wastewater and domestic sewage is gradually increasing.However,wastewater collection and treatment facilities lag behind,so that a large number of wastewater enters urban water,making urban water become gradually black and smelly.In order to provide a good living environment for human beings,a large number of scholars actively explore the treatment technology of black and smelly water.In this paper,the evolution process of black and smelly water was introduced firstly,and then the treatment technology of black and smelly water was summarized.Finally,the prospects for the development of the treatment technology were put forward.

Research progress of lncRNA and miRNA in hepatic ischemia-reperfusion injury

Background:Hepatic ischemia-reperfusion injury(HIRI)is a common complication of liver surgeries,such as hepatectomy and liver transplantation.In recent years,several non-coding RNAs(nc RNAs)including long non-coding RNAs(lnc RNAs)and micro RNAs(mi RNAs)have been identified as factors involved in the pathological progression of HIRI.In this review,we summarized the latest research on lnc RNAs,mi RNAs and the lnc RNA-mi RNA regulatory networks in HIRI.Data sources:The Pub Med and Web of Science databases were searched for articles published up to December 2021 using the following keywords:“hepatic ischemia-reperfusion injury”,“lnc RNA”,“long noncoding RNA”,“mi RNA”and“micro RNA”.The bibliography of the selected articles was manually screened to identify additional studies.Results:The mechanism of HIRI is complex,and involves multiple lnc RNAs and mi RNAs.The roles of lnc RNAs such as AK139328,CCAT1,MALAT1,TUG1 and NEAT1 have been established in HIRI.In addition,numerous mi RNAs are associated with apoptosis,autophagy,oxidative stress and cellular inflammation that accompany HIRI pathogenesis.Based on the literature,we conclude that four lnc RNA-mi RNA regulatory networks mediate the pathological progression of HIRI.Furthermore,the expression levels of some lnc RNAs and mi RNAs undergo significant changes during the progression of HIRI,and thus are potential prognostic markers and therapeutic targets.Conclusions:Complex lnc RNA-mi RNA-m RNA networks regulate HIRI progression through mutual activation and antagonism.It is necessary to screen for more HIRI-associated lnc RNAs and mi RNAs in order to identify novel therapeutic targets.

Research progress on natural products against hepatocellular carcinoma

Hepatocellular carcinoma(HCC)remains a prevalent and challenging malignancy globally,characterized by its numerous causal factors and generally unfavorable prognosis.In the relentless pursuit of effective treatment modalities,natural products have emerged as a promising and relatively non-toxic alternative,garnering significant interest.The integration of natural products with contemporary medical research has yielded encouraging therapeutic outcomes in the management of HCC.This review offers a comprehensive overview of the causal factors underlying HCC,and the diverse treatment options available,and highlights the advancements made by natural products in anti-HCC research.Particularly,we provide an outline of the various types of natural products,their corresponding nomenclature,target molecules,and mechanisms of action that exhibit anti-HCC activities.Natural products are anticipated to play a pivotal role in future comprehensive treatment plans for liver cancer,potentially offering patients improved survival rates and an enhanced quality of life.