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CCTA-AI联合FFR-CT诊断冠状动脉狭窄病变的应用价值研究
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作者 许禹 耿云平 尤国庆 《右江医学》 2024年第5期447-450,共4页
目的评估计算机断层扫描血管成像(CCTA)与人工智能(AI)联合心肌灌注分数(FFR-CT)对冠状动脉狭窄病变的诊断价值。方法选择于2022年1月至2023年2月到南阳市中心医院接受诊治的80例疑似冠状动脉狭窄病变患者作为观察对象。所有患者均接受C... 目的评估计算机断层扫描血管成像(CCTA)与人工智能(AI)联合心肌灌注分数(FFR-CT)对冠状动脉狭窄病变的诊断价值。方法选择于2022年1月至2023年2月到南阳市中心医院接受诊治的80例疑似冠状动脉狭窄病变患者作为观察对象。所有患者均接受CCTA以及冠状动脉造影(CAG)检查,其检查的间隔时间应在14天内,然后通过AI软件自动对CCTA的图像进行重建和计算,同时计算FFR-CT的数值。计算人工智能辅助的心脏计算机断层扫描(CCTA-AI)联合FFR-CT诊断的敏感度、特异度、准确度、阳性预测值和阴性预测值。结果80例患者经CAG检查确诊,72例患者为冠状动脉狭窄病变,占比为90%;8例患者为非冠状动脉狭窄病变,占比为10%。CCTA-AI联合FFR-CT检查的敏感度、特异度、阳性预测值、阴性预测值、准确度以及AUC值均高于CCTA-AI、FFR-CT单独检查,差异有统计学意义(P<0.05)。结论采用CCTA-AI联合FFR-CT检查诊断冠状动脉狭窄病变具有较高的诊断效能,其敏感度及特异度均得到显著提高。 展开更多
关键词 心脏CT血管成像 人工智能 心肌灌注分数 冠状动脉狭窄病变 敏感度 特异度
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冠状动脉周围脂肪CT衰减指数联合CT-FFR对急性冠状动脉综合征患者MACE事件预测价值
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作者 孙刚 常艺桐 +2 位作者 徐娜 孟庆涛 朱霓 《中国CT和MRI杂志》 2024年第7期90-92,共3页
目的探讨分析冠状动脉周围脂肪CT衰减指数(FAI)联合CT-FFR对急性冠状动脉综合征(ACS)患者MACE事件预测价值。方法选择2020年1月~2022年7月在我院接受PCI手术治疗的ACS患者162例,根据患者术后1年是否发生MACE,将其分为MACE组(37例)和非M... 目的探讨分析冠状动脉周围脂肪CT衰减指数(FAI)联合CT-FFR对急性冠状动脉综合征(ACS)患者MACE事件预测价值。方法选择2020年1月~2022年7月在我院接受PCI手术治疗的ACS患者162例,根据患者术后1年是否发生MACE,将其分为MACE组(37例)和非MACE组(125例)。记录两组患者临床资料,并进行FAI及CT-FFR检查,进行多因素Logistic回归分析,并采用ROC曲线分析FAI、CT-FFR对ACS患者PCI术后MACE发生的预测价值。结果MACE组患者FAI显著高于非MACE组患者(P<0.05),且MACE组患者CT-FFR显著低于非MACE组(P<0.05)。CTFFR、FAI、年龄以及血管病变直数进入回归模型(P<0.05),为影响ACS患者PCI术后MACE发生的独立危险因素。采用ROC曲线分析FAI、CT-FFR对ACS患者PCI术后MACE的预测价值,结果显示,FAI曲线下面积为0.695、CT-FFR曲线下面积为0.771,FAI联合CT-FFR曲线下面积为0.943。结论冠状动脉周围脂肪CT衰减指数联合CT血流储备分数对冠状动脉综合征患者PCI术后MACE发生具有着良好的预测价值,术前完善相关检查评估,对于高危患者及时采取有效的预防治疗对策,对于改善患者临床预后具有重要意义。 展开更多
关键词 冠状动脉周围脂肪CT衰减指数 CT-ffr 急性冠状动脉综合征 MACE 预测
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冠状动脉CT血管造影计算FFR深度学习方法的诊断临床研究
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作者 周建昌 纪丽萍 +2 位作者 蒙志宏 张帆 曹宇佳 《中国CT和MRI杂志》 2024年第5期94-96,共3页
目的本研究旨在评估冠状动脉CT血管造影计算分流量储备(fractional flow reserve,FFR)深度学习方法的诊断准确性研究,以期为临床诊治提供参考。方法这是一项单中心的前瞻性研究,63名患者参加了深度学习FFR的诊断性能评估。为了评估冠状... 目的本研究旨在评估冠状动脉CT血管造影计算分流量储备(fractional flow reserve,FFR)深度学习方法的诊断准确性研究,以期为临床诊治提供参考。方法这是一项单中心的前瞻性研究,63名患者参加了深度学习FFR的诊断性能评估。为了评估冠状动脉狭窄的缺血风险,提出了冠状动脉三维几何形状的自动量化方法和基于深度学习的FFR预测方法。以线状FFR为参考标准,评价深度学习FFR的诊断性能。采用受试者-操作特征曲线下面积(AUC)分析确定主要评价因子。结果对于每个患者水平,以参照FFR测量的临界值≤0.8时,深度学习FFR的AUC为0.928,缺血相关病变方面比CTA狭窄严重程度0.664表现出更高的诊断性能。深度学习FFR与FFR相关(R=0.686,P<0.001),平均差值为-0.006±0.0091(P=0.619)。二次评价的准确性、敏感性、特异性分别为87.3%、97.14%、95.45%。结论深度学习FFR是一种新的方法,可以有效地评估冠状动脉狭窄的功能意义。 展开更多
关键词 冠状动脉CT血管造影 深度学习模型 分流量储备
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基于CCTA的ΔCT-FFR对重度钙化冠状动脉功能学评估的临床价值分析
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作者 魏凯 王玺 +4 位作者 何柏 赵子强 张威 荆晶 单冬凯 《解放军医学杂志》 CAS CSCD 北大核心 2024年第2期144-151,共8页
目的探讨基于冠状动脉计算机断层扫描血管成像(CCTA)的血流储备分数(CT-FFR)和冠状动脉病变最严重狭窄处的近端与远端CT-FFR测量差值(ΔCT-FFR)对重度钙化冠状动脉功能学评估诊断效能的临床价值。方法收集2018年1月-2019年6月解放军总... 目的探讨基于冠状动脉计算机断层扫描血管成像(CCTA)的血流储备分数(CT-FFR)和冠状动脉病变最严重狭窄处的近端与远端CT-FFR测量差值(ΔCT-FFR)对重度钙化冠状动脉功能学评估诊断效能的临床价值。方法收集2018年1月-2019年6月解放军总医院心血管内科收治住院的107例冠心病(CAD)患者的149支血管进行回顾性分析。所有患者住院期间依次进行CCTA、CT-FFR、侵入性冠状动脉造影(ICA)和有创血流储备分数(FFR)检查。以单支冠状动脉钙化积分(CACS)≥100判断为血管水平的重度钙化,根据CACS水平将冠状动脉分为CACS≥100组(n=56)和CACS<100组(n=93)。以FFR≤0.8作为诊断冠状动脉血流动力学异常的“金标准”,ΔCT-FFR定义为冠状动脉病变最严重狭窄处近端与远端CTFFR的测量差值。采用Pearson相关和Bland-Altman图评估血管水平CT-FFR与FFR值的相关性和一致性。通过ΔCT-FFR校正CT-FFR的检测结果,使用Delong检验比较不同诊断方法间受试者工作特征曲线(ROC)的曲线下面积(AUC),在血管水平分析其对重度钙化冠状动脉功能学评估诊断效能的增量价值。结果在血管水平CT-FFR与FFR值具有较好的相关性(CACS≥100组:r=0.71,P<0.01;CACS<100组:r=0.73,P<0.01)和一致性(CACS≥100组:Mean=-0.01,P=0.25;CACS<100组:Mean=0,P=0.96)。与CACS<100组比较,CACS≥100组FFR(0.80±0.08 vs.0.84±0.09,P=0.004)和CT-FFR值(0.81±0.06 vs.0.85±0.06,P<0.001)明显降低,ΔCT-FFR值(0.14±0.06 vs.0.09±0.06,P<0.001)明显增高。与CACS<100组比较,CACS≥100组CT-FFR的诊断效能明显下降[(AUC=0.792,95%CI 0.663~0.889)vs.(AUC=0.929,95%CI 0.856~0.972),P=0.04]。经ΔCT-FFR校正诊断后,CACS≥100组CT-FFR的诊断效能较前明显提高[(AUC=0.876,95%CI 0.760~0.949)vs.(AUC=0.792,95%CI0.663~0.889),P=0.02],与CACS<100组差异无统计学意义(P=0.37)。结论对于重度钙化冠状动脉,经ΔCT-FFR校正后,CT-FFR评估冠状动脉功能学的诊断效能明显提高。 展开更多
关键词 冠心病 冠状动脉计算机断层扫描血管成像 血流储备分数 重度钙化
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冠状动脉树重建扩大到较小动脉提高FFRCT准确性的研究
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作者 周建昌 纪丽萍 +2 位作者 蒙志宏 张帆 曹宇佳 《中国CT和MRI杂志》 2024年第8期54-56,共3页
目的本研究旨在通过在计算流体动力学(CFD)领域扩展冠脉树来提高基于冠状动脉CT血管成像(coronary CT angiography,CCTA)的血流储备分数(FFR)的准确性。进行了一项观察性研究,以评估将冠状动脉树分析从最小直径1.2mm扩展到0.8 mm的效果... 目的本研究旨在通过在计算流体动力学(CFD)领域扩展冠脉树来提高基于冠状动脉CT血管成像(coronary CT angiography,CCTA)的血流储备分数(FFR)的准确性。进行了一项观察性研究,以评估将冠状动脉树分析从最小直径1.2mm扩展到0.8 mm的效果。方法对接受CCTA和介入性FFR治疗的患者进行回顾性研究。76名患者符合纳入标准。重建三维冠状动脉树,生成具有不同管腔直径下限(1.2 mm和0.8 mm)的有限元网格。根据Murray定律定义了出口边界条件。应用NKS方法求解CFD控制方程,得到FFRCT。结果在个体患者水平上,将冠状动脉树的最小直径从1.2mm扩大到0.8mm,FFRCT的灵敏度提高了16.7%(P=0.022),这导致四个假阴性病例转变为真阳性病例。ROC曲线的AUC值由0.74增至0.83。此外,NKS方法可以解决在2160个处理器核的情况下,在10.5分钟内将冠状动脉树扩展到0.8 mm管腔直径的计算问题。结论将重建的冠脉扩大到较小的管腔直径可以显著提高FFRCT的敏感性,NKS方法可以为未来的临床应用提供良好的计算时间。 展开更多
关键词 冠状动脉狭窄 心肌血流储备分数 计算机断层血管造影术 流体力学
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冠状动脉CT血管成像联合CT-FFR对冠心病心肌缺血影响因素的研究
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作者 徐敏 瞿华 《中国现代医生》 2024年第25期66-69,共4页
目的应用冠状动脉CT血管成像(coronary CT angiography,CCTA)联合冠状动脉CT血流储备分数(coronary CT angiography derived fractional flow reserve,CT-FFR)探讨冠心病患者心肌缺血的影像学特征,并探讨冠心病患者心肌缺血的影响因素... 目的应用冠状动脉CT血管成像(coronary CT angiography,CCTA)联合冠状动脉CT血流储备分数(coronary CT angiography derived fractional flow reserve,CT-FFR)探讨冠心病患者心肌缺血的影像学特征,并探讨冠心病患者心肌缺血的影响因素。方法回顾性选取2023年1月至11月于浙江中医药大学附属杭州市中医院就诊并行CCTA检查的86例患者,根据测量的CT-FFR值将其分为缺血组(CT-FFR≤0.80,45例)与非缺血组(CT-FFR>0.80,41例),比较两组患者的斑块特征,采用多因素Logistic回归分析探讨冠心病患者心肌缺血的影响因素。结果缺血组患者的糖尿病占比显著高于非缺血组(P<0.05)。共有150支冠状动脉显示有斑块,斑块最常见部位为左前降支(114个)。对212个斑块进行分析,其中缺血组68个斑块,非缺血组144个斑块。非缺血组钙化斑块占比显著高于缺血组(P<0.05);缺血组管腔狭窄程度、斑块体积、脂类成分占比、纤维脂类成分体积均显著大于非缺血组,斑块纤维成分体积显著小于非缺血组(P<0.05)。多因素Logistic回归分析结果显示,管腔狭窄程度(OR=1.054,P=0.026)和斑块体积(OR=1.027,P=0.048)均是冠心病患者心肌缺血的的影响因素。结论管腔狭窄程度及斑块体积均是冠心病患者心肌缺血的影响因素,可对此类患者进行针对性的治疗。 展开更多
关键词 冠状动脉CT血管成像 心肌缺血 斑块特征 血流储备分数
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FFR指导下经乳内动脉桥血管行前降支远端血运重建1例
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作者 寇晓庆 甘义荣 +3 位作者 王延震 王沛 谢定雄 张钲 《中国循证心血管医学杂志》 2024年第8期1009-1009,1016,共2页
1病例患者男性,66岁,主因“胸闷、气短3年,加重4 d”于2021年6月22日入院。患者3年前开始反复于步行时出现胸闷、气短,休息数分钟后可缓解。入院前4 d胸闷、气短发作较前频繁。既往高血压、糖尿病病史,血压、血糖控制欠佳。既往吸烟30年... 1病例患者男性,66岁,主因“胸闷、气短3年,加重4 d”于2021年6月22日入院。患者3年前开始反复于步行时出现胸闷、气短,休息数分钟后可缓解。入院前4 d胸闷、气短发作较前频繁。既往高血压、糖尿病病史,血压、血糖控制欠佳。既往吸烟30年,20支/d,未戒烟。7年前行冠状动脉旁路移植术(coronary artery bypass graft,CABG),移植血管为左乳内动脉(left internal mammary artery,LIMA)-左前降支(left anterior descending branch,LAD)。 展开更多
关键词 乳内动脉桥 桥血管 ffr 前降支
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基于AI的CT-FFR在胸痛胸闷疑似冠心病患者诊断中的应用价值
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作者 朱先清 刘云峰 +4 位作者 王宝春 王怡 胡茂能 马天宇 梁有峰 《现代科学仪器》 2024年第4期143-148,共6页
目的:探究基于人工智能(AI)的CT血管造影血流储备分数(CT-FFR)在胸痛疑似冠心病患者诊断中的应用价值。方法:选取2019年1月至2024年1月我院60例疑似冠心病患者,以ICA检测结果为金标准,分析基于AI的CT-FFR对胸痛胸闷疑似冠心病患者的诊... 目的:探究基于人工智能(AI)的CT血管造影血流储备分数(CT-FFR)在胸痛疑似冠心病患者诊断中的应用价值。方法:选取2019年1月至2024年1月我院60例疑似冠心病患者,以ICA检测结果为金标准,分析基于AI的CT-FFR对胸痛胸闷疑似冠心病患者的诊断价值。结果:基于AI的CT-FFR诊断疑似冠心病患的准确度为88.33%、灵敏度为93.33%、特异度为73.33%,AUC为0.849(95%CI:0.714~0.985),具有较高的诊断价值。结论:基于AI的CT-FFR技术对胸痛胸闷疑似冠心病患者具有较高的诊断价值。 展开更多
关键词 冠心病 胸痛 人工智能 冠状动脉CT血管造影 血流储备分数
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基于冠状动脉CT的FFR在冠心病患者临床诊断中对诊断灵敏度及特异度的影响研究
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作者 徐天佩 江永尧 李叶明 《影像技术》 CAS 2024年第2期9-12,19,共5页
目的:分析基于冠状动脉CT的血流储备分数(FFR)在冠心病患者临床诊断中对诊断灵敏度及特异度的影响。方法:此次研究总共纳入48例研究对象,均是2020年12月-2022年12月到我院诊治的疑似冠心病患者,均接受冠状动脉造影检查(CAG)、冠脉CT造... 目的:分析基于冠状动脉CT的血流储备分数(FFR)在冠心病患者临床诊断中对诊断灵敏度及特异度的影响。方法:此次研究总共纳入48例研究对象,均是2020年12月-2022年12月到我院诊治的疑似冠心病患者,均接受冠状动脉造影检查(CAG)、冠脉CT造影检查(CCTA)下测定FFR值检查。将CAG作为参照标准,统计CCTA下测定FFR值的诊断效能。结果:将CAG作为参照标准,48例疑似冠心病患者经CT-FFR检查后,真阳38例,假阳1例,真阴5例,假阴4例。CT-FFR诊断冠心病的敏感度为90.48%(38/42),特异度为83.33%(5/6),准确率为89.58%(43/48)。在冠心病检出率上,CT-FFR检查低于CAG检查,对比差异有统计学意义(P<0.05)。结论:CT冠脉造影下测定FFR值用于冠心病的临床诊断效果良好,诊断敏感度与特异度较高,可作为临床诊断冠心病的辅助手段,临床可进一步推广应用。 展开更多
关键词 冠心病 基于冠状动脉CT的ffr 灵敏度 特异度
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Many Kinds of Reserved Judgement in No-Data Problem
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作者 Houju Hori Jr. 《Applied Mathematics》 2024年第1期1-8,共8页
The reserved judgment can be broadly categorized into three types: Re-Do, Re-Set, and Natural Flowing Case (i.e. step by step in Re-Try). Hori et al. constructed the Bayes-Fuzzy Estimation and demonstrated that system... The reserved judgment can be broadly categorized into three types: Re-Do, Re-Set, and Natural Flowing Case (i.e. step by step in Re-Try). Hori et al. constructed the Bayes-Fuzzy Estimation and demonstrated that system theory can be applied to the possibility of Markov processes, and that decision-making approaches can be applied to sequential Bayes estimation. In this paper, we focus on the Natural Flowing Case within reserved judgment. Here, the possibility of oblique (or principal) factor rotation is considered as a part of the tandem fuzzy system that follows step by step for sequential Bayes estimation. Ultimately, we achieve a significant result whereby the expected utility can be calculated automatically without the need to construct a utility function for reserved judgment. There, this utility in Re-Do can be calculated by the prior utility, and that utility in Re-set does not exist by our research in this paper. Finally, we elucidate the relationship between fuzzy system theory and fuzzy decision theory through an applied example of Bayes-Fuzzy theory. Fuzzy estimation can be applied to only normal making decision, but it is impossible to apply abnormal decision problem. Our Vague, specially Type 2 Vague can be applied to abnormal case, too. 展开更多
关键词 Bayes-Fuzzy Estimation Re-Do Re-Set Indifferent Zone reserved Judgement
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Peat properties of a tropical forest reserve adjacent to a fire-break canal
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作者 Dayang Nur Sakinah Musa Mohd Zahirasri Mohd Tohir +3 位作者 Xinyan Huang Luqman Chuah Abdullah Mohamad Syazaruddin Md Said Muhammad Firdaus Sulaiman 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第1期155-167,共13页
Tropical peat comprises decomposed dead plant material and acts like a sponge to absorb water,making it fully saturated.However,drought periods dry it readily and increases its vulnerability to fire.Peat fires emit gr... Tropical peat comprises decomposed dead plant material and acts like a sponge to absorb water,making it fully saturated.However,drought periods dry it readily and increases its vulnerability to fire.Peat fires emit greenhouse gases and particles contributing to haze,and prevention by constructing fire-break canals to reduce fire spread into forest reserves is crucial.This paper aims to determine peat physical and chemical properties near a fire-break canal at different fire frequency areas.Peat sampling was conducted at two forest reserves in Malaysia which represent low fire frequency and high fire frequency areas.The results show that peat properties were not affected by the construction of a fire-break canal,however lignin and cellulose content increased significantly from the distance of the canal in both areas.The study concluded that fire frequency did not significantly influence peat properties except for porosity.The higher fibre content in the high frequency area did not influence moisture content nor the ability to regain moisture.Thus,fire frequency might contribute differently to changes in physical and chemical properties,hence management efforts to construct fire-break canals and restoration efforts should protect peatlands from further degradation.These findings will benefit future management and planning for forest reserves. 展开更多
关键词 Peat fire Peat properties Fire-break canals Forest reserves
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Ovarian Reserve in a Population of Obese Infertile Patients in Kinshasa
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作者 Charlie-Junior Bikuelo Bikuelo Dan Ngoyi Kabengele +6 位作者 Justin Mboloko Esimo Athéna Mwakila Asana Guy Monzango Sibo Charles Moangi Bapanzi Patrick Mogwo Sendeke Pathou Mampuya Ipanga Annie Egbolo Azima 《Open Journal of Obstetrics and Gynecology》 2024年第10期1657-1669,共13页
Background: The ovarian reserve, which is an important marker in the management of couple infertility, undergoes depletion over time. This depletion could accelerate in the presence of certain circumstances, such as o... Background: The ovarian reserve, which is an important marker in the management of couple infertility, undergoes depletion over time. This depletion could accelerate in the presence of certain circumstances, such as obesity. The contradictory results of studies on the impact of obesity on the ovarian reserve throughout the world accelerated ovarian ageing in infertile women from Kinshasa, as well as the high rate of obese women in this population, seemed necessary to undertake this study to find out if this obesity impacted the ovarian reserve of Kinshasa women. The objective of this study was to identify the profile of markers of ovarian reserve in obese infertile patients according to certain characteristics. Method: A case-control study with retrospective data collection on 439 obese infertile patients (cases) and 439 normal-weight infertile patients (controls) who had consulted for the desire to conceive at the University Hospital of Kinshasa and the Edith Medical Center between January 2016 and December 2021. Results: The average age of the patients was 33.6 years ± 4.3 years, with 47.8% of patients aged at least 35 years. Menarche and menstrual duration were correlated with AMH in linear regression (p = 0.043 and 0.021, respectively). Late menarche and irregular cycle were risk factors for ovarian ageing [OR: 4.6;95% CI: (1.052 - 20.636);p = 0.043 and OR: 4.8;95% CI: (1.633 - 14.566);p = 0.005] while PCO was a protective factor for ovarian ageing [OR: 0.109;95% CI: (0.182 - 0.652);p = 0.015]. Conclusion: Within the limits of our study, we found that the more obese the patients were, the faster the ovaries aged. 展开更多
关键词 Ovarian reserve Obesity INFERTILITY AMH FSH
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Swelling pressure evolution characterization of strong expansive soil considering the influence of reserved expansion deformation
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作者 LI Tianguo KONG Lingwei +1 位作者 GUO Aiguo YAN Junbiao 《Journal of Mountain Science》 SCIE CSCD 2024年第1期252-270,共19页
Numerous engineering cases have demonstrated that the expansive soil channel slope remains susceptible to damage with the implementation of a rigid or closed protective structure. It is common for the protective struc... Numerous engineering cases have demonstrated that the expansive soil channel slope remains susceptible to damage with the implementation of a rigid or closed protective structure. It is common for the protective structure to experience bulging failure due to excessive swelling pressure. To investigate the swelling pressure properties of expansive soil, the constant volume test was employed to study the influence of water content and reserved expansion deformation on the characteristics of swelling pressure in strong expansive soils, and also to explore the evolution mechanism of the swelling pressure. The findings demonstrate that the swelling pressure-time curve can be classified into swelling pressure-time softening and swelling pressure-time stability type. The swelling pressuretime curve of the specimen with low water content is the swelling pressure-time softening type, and the softening level will be weakened with increasing reserved expansion deformation. Besides, the maximum swelling pressure Psmax decreases with increasing water content and reserved expansion deformation, especially for expansion ratio η from 24% to 37%. The reserved deformation has little effect on reducing Psmax when it is beyond 7% of the expansion rate. The specimen with low water content has a more homogeneous structure due to the significant expansion-filling effect, and the fracture and reorganization of the aggregates in the specimens with low water content cause the swelling pressure-time softening behavior. In addition, the proposed swelling pressure-time curve prediction model has a good prediction on the test results. If necessary, a deformation space of about 7% expansion rate is recommended to be reserved in the engineering to reduce the swelling pressure except for keeping a stable water content. 展开更多
关键词 Expansive soil Swelling pressure reserved expansion deformation Water content
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Efficacy of intraovarian autologous platelet-rich plasma administration in women with low ovarian reserve: A systematic review and meta-analysis
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作者 Yasmin Sabina Sa’diah Agung Dewanto Lukman A Chandra 《Asian pacific Journal of Reproduction》 CAS 2024年第2期60-67,共8页
Objective:To conduct a systematic examination and meta-analysis of the most reliable data from experimental studies evaluating the efficacy of autologous platelet-rich plasma(PRP)on low ovarian reserve.Methods:A compr... Objective:To conduct a systematic examination and meta-analysis of the most reliable data from experimental studies evaluating the efficacy of autologous platelet-rich plasma(PRP)on low ovarian reserve.Methods:A comprehensive search was performed utilizing pertinent search terms across electronic databases,including PubMed,Cochrane,and Google Scholar.We included studies that assigned infertile women with low ovarian reserve in experimental studies.Ovarian reserve parameters were measured before and after PRP injection into ovaries.The data of each study was retrieved and subsequently compiled.Results:Of 301 articles collected and reviewed,six studies were finally included in the meta-analysis.Following PRP injection,infertile women showed a non-significant increase in anti-Mullerian hormone(AMH)level(MD=0.10;95%CI-0.04,0.23),a significant increase in antral follicular count(AFC)(MD=1.88;95%CI 0.47,3.29),and a non-significant reduction in follicle-stimulating hormone(FSH)level(MD=-0.22;95%CI-8.32,7.87).Conclusions:Autologous PRP may increase AFC,but not AMH.Although it is found beneficial in enhancing ovarian reserve(AFC),further research with strong evidence is still required. 展开更多
关键词 Platelet-rich plasma Low ovarian reserve Ovarian rejuvenation
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The Effect of Uterine Artery Occlusion with Tourniquet on Ovarian Reserve during Open Myomectomy at a University Teaching Hospital in Southern Nigeria
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作者 William Amebeobari Mube Justina Omoikhefe Alegbeleye Ngozi Clare Orazulike 《Advances in Reproductive Sciences》 CAS 2024年第1期37-50,共14页
Background: The most common surgical treatment for symptomatic uterine fibroids, particularly in women with fertility concerns, is open myomectomy. Given the high vascularity of the uterus, haemorrhage during the proc... Background: The most common surgical treatment for symptomatic uterine fibroids, particularly in women with fertility concerns, is open myomectomy. Given the high vascularity of the uterus, haemorrhage during the procedure is a serious risk that is often mitigated with a uterine tourniquet. Aim and Objectives: To evaluate the effect of uterine artery occlusion with a tourniquet during open myomectomy on ovarian reserve using serial anti-Mullerian hormone (AMH) measurements. Materials and Methods: This was a prospective longitudinal study with a quasi-experimental design and a convenient sampling technique. The study enrolled 47 women who had abdominal myomectomy between September 1, 2021, and March 31, 2022, at the University of Port Harcourt Teaching Hospital. Blood samples were collected before anaesthesia was administered in theatre, on day two, and three months after open abdominal myomectomy for anti-Mullerian hormone assay. The data was collected using a semi-structured proforma, entered into an Excel spreadsheet, and analyzed using SPSS version 25.0 with a 95% confidence interval. Statistical significance level was set at 0.05. Results: The pre-surgery AMH mean value was 1.67 ± 1.44 ng/ml, while the values after using a uterine tourniquet at myomectomy on the second day and three months later were 1.22 ± 1.24 ng/ml and 1.59 ± 1.43 ng/ml, respectively. There was no statistically significant change in AMH levels, and there was no statistically significant relationship between blood loss and tourniquet time and AMH after open abdominal myomectomy. Conclusion: The use of a uterine tourniquet and blood loss during open myomectomy has no effect on ovarian reserve. 展开更多
关键词 Uterine Tourniquet Open Abdominal Myomectomy Ovarian reserve Anti-Mullerian Hormone NIGERIA
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Impacts of Human Activities and Season on Species Diversity and Abundance of Butterflies in Mpanga Kipengere Game Reserve and Surrounding Farmlands, Tanzania
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作者 Privatus M. Kasisi Nsajigwa Mbije Paul Lyimo 《Open Journal of Ecology》 2024年第4期274-291,共18页
Maintaining natural habitats is crucial for the preservation of insects and other species that indicate environmental changes. However, the Mpanga/Kipengere Game Reserve and its surrounding farmlands are facing distur... Maintaining natural habitats is crucial for the preservation of insects and other species that indicate environmental changes. However, the Mpanga/Kipengere Game Reserve and its surrounding farmlands are facing disturbance due to human activities, which is putting many wildlife species, particularly larger mammals, at risk. To determine the impact of human activities on butterfly species diversity and abundance in the reserve and its surrounding areas, we conducted a study from November 2021 to October 2023. We collected butterfly data using transect walks and baited traps in two habitat types. Our study yielded 2799 butterfly Individuals ranging in 124 species divided into five families habitat, season, and anthropogenic factors are significant environmental variables influencing species diversity and abundance of butterflies. Therefore, it’s important to protect habitat and dry-season water for the conservation of invertebrates such as butterflies. Our study findings provide essential information for ecological monitoring and future assessment of the Mpanga/Kipengere Game Reserve ecosystem health. 展开更多
关键词 Mpanga Kipengere Game reserve Species Diversity HABITAT Butterflies SEASON Human Activities
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Seasonal Abundance and Diversity of Birds of Prey and Owls in Al Wathba Wetland Reserve in Abu Dhabi, UAE
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作者 Shakeel Ahmed Salim Jáved +3 位作者 Shahid B. Khan Eissa Al Hammadi Abdullah Al Hammadi Nouf Sameer Alqadi 《Open Journal of Ecology》 2024年第3期228-244,共17页
Inland wetlands in Abu Dhabi Emirate are wintering and stopover sites for migratory birds of prey. We conducted long-term regular monitoring surveys in Al Wathba Wetland Reserve (AWWR) from January 1995 to December 20... Inland wetlands in Abu Dhabi Emirate are wintering and stopover sites for migratory birds of prey. We conducted long-term regular monitoring surveys in Al Wathba Wetland Reserve (AWWR) from January 1995 to December 2022. Both diurnal and occasionally nocturnal surveys were undertaken to record the migratory raptors and owls in the Wetland Reserve. During the study, a total of 1282 regular monitoring visits were undertaken and 27 species of diurnal raptors and owls representing five families and three orders were detected. These represent 57% of the total species of birds of prey recorded in the UAE. Overall, 63% of all the species that we observed were Accipitriformes followed by 26% Falconiformes and 11% Strigiformes. We found that changes in mean daily temperature have a positive effect on raptor species diversity and abundance in the Wetland Reserve. The species encounter rate was higher in low temperature as compared to high temperature and overall regression equation was statistically significant F (4, 1126) = 8.49), p = 0.00). However, the numbers of raptors did not vary significantly across the years (p = 0.51). Western Marsh-harrier (Circus aeruginosus) and Greater Spotted Eagle (Clanga clanga) were recorded to be the most abundant species in the wetland reserve followed by Common Kestrel (Falco tinnunculus). However, the encounter rate of globally threatened Greater Spotted Eagle was detected to have significantly decreased since 2016. Moreover, 63% of the species detected were uncommon and rarely recorded such as 1) Saker Falcon 2) Lanner Falcon 3) Long-eared Owl & Merlin, which were the rare records from the wetland reserve. Furthermore, 27 years of regular monitoring in the wetland have yielded diverse diurnal raptors and owl fauna (H) = 0.83, (E) = 1.43 (Shannon Diversity Index). The results demonstrate that long-term monitoring surveys in arid environments are essential to determine the trends in the raptor populations and to document rare and globally important species. 展开更多
关键词 Wetland reserve RAPTORS Abundance DIVERSITY Abu Dhabi Inland Wetland AWWR Greater Spotted Eagle
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Interaction between catechol-O-methyltransferase Val/Met polymorphism and cognitive reserve for negative symptoms in schizophrenia
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作者 Wen-Peng Hou Xiang-Qin Qin +6 位作者 Wei-Wei Hou Yun-Yi Han Qi-Jing Bo Fang Dong Fu-Chun Zhou Xian-Bin Li Chuan-Yue Wang 《World Journal of Psychiatry》 SCIE 2024年第5期695-703,共9页
BACKGROUND Cognitive reserve(CR)and the catechol-O-methyltransferase(COMT)Val/Met polymorphism are reportedly linked to negative symptoms in schizophrenia.However,the regulatory effect of the COMT genotype on the rela... BACKGROUND Cognitive reserve(CR)and the catechol-O-methyltransferase(COMT)Val/Met polymorphism are reportedly linked to negative symptoms in schizophrenia.However,the regulatory effect of the COMT genotype on the relationship between CR and negative symptoms is still unexamined.AIM To investigate whether the relationship between CR and negative symptoms could be regulated by the COMT Val/Met polymorphism.METHODS In a cross-sectional study,54 clinically stable patients with schizophrenia underwent assessments for the COMT genotype,CR,and negative symptoms.CR was estimated using scores in the information and similarities subtests of a short form of the Chinese version of the Wechsler Adult Intelligence Scale.RESULTS COMT Met-carriers exhibited fewer negative symptoms than Val homozygotes.In the total sample,significant negative correlations were found between negative symptoms and information,similarities.Associations between information,similarities and negative symptoms were observed in Val homozygotes only,with information and similarities showing interaction effects with the COMT genotype in relation to negative symptoms(information,β=-0.282,95%CI:-0.552 to-0.011,P=0.042;similarities,β=-0.250,95%CI:-0.495 to-0.004,P=0.046).CONCLUSION This study provides initial evidence that the association between negative symptoms and CR is under the regulation of the COMT genotype in schizophrenia. 展开更多
关键词 Catechol-O-methyltransferase Val/Met polymorphism Cognitive reserve Crystallized intelligence Negative symptoms SCHIZOPHRENIA
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Clinical application of reserved gastric tube in neuroendoscopic endonasal surgery for pituitary tumor
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作者 Xi Chen Long-Yao Zhang +3 位作者 Zhi-Feng Wang Yi Zhang Yu-Hua Yin Xue-Jian Wang 《World Journal of Clinical Oncology》 2024年第3期411-418,共8页
BACKGROUND The neuroendoscopic approach has the advantages of a clear operative field,convenient tumor removal,and less damage,and is the development direction of modern neurosurgery.At present,transnasal surgery for ... BACKGROUND The neuroendoscopic approach has the advantages of a clear operative field,convenient tumor removal,and less damage,and is the development direction of modern neurosurgery.At present,transnasal surgery for sphenoidal pituitary tumor is widely used.But it has been found in clinical practice that some patients with this type of surgery may experience post-operative nausea and vomiting and other discomforts.AIM To explore the effect of reserved gastric tube application in the neuroendoscopic endonasal resection of pituitary tumors.METHODS A total of 60 patients who underwent pituitary adenoma resection via the endoscopic endonasal approach were selected and randomly divided into the experimental and control groups,with 30 in each group.Experimental group:After anesthesia,a gastric tube was placed through the mouth under direct vision using a visual laryngoscope,and the fluid accumulated in the oropharynx was suctioned intermittently with low negative pressure throughout the whole process after nasal disinfection,during the operation,and when the patient recovered from anesthesia.Control group:Given the routine intraoperative care,no gastric tube was left.The number of cases of nausea/vomiting/aspiration within 24 h post-operation was counted and compared between the two groups;the scores of pharyngalgia after waking up,6 h post-operation,and 24 h postoperation.The frequency of postoperative cerebrospinal fluid leakage and intracranial infection were compared.The hospitalization days of the two groups were statistically compared.RESULTS The times of postoperative nausea and vomiting in the experimental group were lower than that in the control group,and the difference in the incidence of nausea was statistically significant(P<0.05).After the patient woke up,the scores of sore throat 6 h after the operation and 24 h after operation were lower than those in the control group,and the difference was statistically significant(P<0.05).The number of cases of postoperative cerebrospinal fluid leakage and intracranial infection was higher than that of the control group,but there was no statistically significant difference from the control group(P>0.05).The hospitalization days of the experimental group was lower than that of the control group,and the difference was statistically significant(P<0.05).CONCLUSION Reserving a gastric tube in the endoscopic endonasal resection of pituitary tumors,combined with intraoperative and postoperative gastrointestinal decompression,can effectively reduce the incidence of nausea,reduce the number of vomiting and aspiration in patients,and reduce the complications of sore throat The incidence rate shortened the hospitalization days of the patients. 展开更多
关键词 NEUROENDOSCOPY Endonasal approach Pituitary tumor reserved gastric tube NAUSEA VOMITING ASPIRATION COMPLICATIONS
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慢性冠脉综合征患者血尿酸及钙化积分对CT-FFR的影响
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作者 徐彧 杜丰夷 +2 位作者 袁小佳 赵天佐 陈正光 《中国中西医结合影像学杂志》 2024年第2期175-179,共5页
目的:探讨血尿酸及钙化积分对深度学习算法下冠脉综合征(CCS)患者血流储备分数(CT-FFR)的影响。方法:回顾性分析150例冠状动脉(冠脉)CTA(CCTA)示靶血管狭窄的慢性CCS患者,采用深度学习法计算其CT-FFR,取3支靶血管中最低值作为该患者CT-F... 目的:探讨血尿酸及钙化积分对深度学习算法下冠脉综合征(CCS)患者血流储备分数(CT-FFR)的影响。方法:回顾性分析150例冠状动脉(冠脉)CTA(CCTA)示靶血管狭窄的慢性CCS患者,采用深度学习法计算其CT-FFR,取3支靶血管中最低值作为该患者CT-FFR,按CT-FFR>0.8及CT-FFR≤0.8分为正常组77例、异常组73例,比较2组血尿酸值及总钙化积分;采用SPSS26.0统计软件对CT-FFR、血尿酸、钙化积分行Pearson分析;使用logistic回归分析且通过ROC曲线评估其诊断效能。结果:2组在钙化积分上差异有统计学意义(Z=-5.958,P<0.05),而血尿酸差异无统计学意义(t=-0.448,P>0.05);Pearson相关分析得出,钙化积分与CT-FFR呈显著负相关(r=-0.556,P<0.05);ROC曲线的AUC为0.782,且达到病变程度(CT-FFR≤0.8)的钙化积分阈值为313.05分,约登指数为0.464,其诊断准确率为78.2%,敏感度为68.5%,特异度为77.9%。结论:冠脉钙化积分可能影响CTFFR,可预测功能性缺血的发生,即钙化积分越高,血管功能越差,CT-FFR越低,缺血越严重。CCS患者血尿酸是否与CT-FFR存在相关性有待进一步研究。 展开更多
关键词 血尿酸 钙化积分 血流储备分数 冠状动脉 心肌缺血
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