AIM:To detect and manage residual common bile duct(CBD)stones using ultraslim endoscopic peroral cholangioscopy(POC)after a negative balloon-occluded cholangiography.METHODS:From March 2011 to December 2011,a cohort o...AIM:To detect and manage residual common bile duct(CBD)stones using ultraslim endoscopic peroral cholangioscopy(POC)after a negative balloon-occluded cholangiography.METHODS:From March 2011 to December 2011,a cohort of 22 patients with CBD stones who underwent both endoscopic retrograde cholangiography(ERC)and direct POC were prospectively enrolled in this study.Those patients who were younger than 20 years of age,pregnant,critically ill,or unable to provide informed consent for direct POC,as well as those with concomitant gallbladder stones or CBD with diameters less than 10 mm were excluded.Direct POC using an ultraslim endoscope with an overtube balloon-assisted technique was carried out immediately after a negative balloon-occluded cholangiography was obtained.RESULTS:The ultraslim endoscope was able to be advanced to the hepatic hilum or the intrahepatic bile duct(IHD)in 8 patients(36.4%),to the extrahepatic bile duct where the hilum could be visualized in 10 patients(45.5%),and to the distal CBD where the hilum could not be visualized in 4 patients(18.2%).The procedure time of the diagnostic POC was 8.2 ± 2.9 min(range,5-18 min).Residual CBD stones were found in 5(22.7%)of the patients.There was one residual stone each in 3 of the patients,three in 1 patient,and more than five in 1 patient.The diameter of the residual stones ranged from 2-5 mm.In 2 of the patients,the residual stones were successfully extracted using either a retrieval balloon catheter(n = 1)or a basket catheter(n = 1)under direct endoscopic control.In the remaining 3 patients,the residual stones were removed using an irrigation and suction method under direct endoscopic visualization.There were no serious procedure-related complications,such as bleeding,pancreatitis,biliary tract infection,or perforation,in this study.CONCLUSION:Direct POC using an ultraslim endoscope appears to be a useful tool for both detecting and treating residual CBD stones after conventional ERC.展开更多
Common bile duct(CBD)stone is a common biliary problem,which often requires endoscopic approach as the initial treatment option.Roughly,7%-12%of the subjects who experience cholecystectomy were subsequently referred t...Common bile duct(CBD)stone is a common biliary problem,which often requires endoscopic approach as the initial treatment option.Roughly,7%-12%of the subjects who experience cholecystectomy were subsequently referred to biliary endoscopist for further management.In general,there are three classifications of difficult CBD stone,which are based on the characteristics of the stone(larger than 15 mm,barrel or square-shaped stones,and hard consistency),accessibility to papilla related to anatomical variations,and other clinical conditions or comorbidities of the patients.Currently,endoscopic papillary large balloon dilation(EPLBD)of a previous sphincterotomy and EPLBD combined with limited sphincterotomy performed on the same session is still recommended by the European Society of Gastrointestinal Endoscopy as the main approach in difficult CBD stones with history of failed sphincterotomy and balloon and/or basket attempts.If failed extraction is still encountered,mechanical lithotripsy or cholangioscopy-assisted lithotripsy or extracorporeal shockwave lithotripsy can be considered.Surgical approach can be considered when stone extraction is still failed or the facilities to perform lithotripsy are not available.To our knowledge,conflicting evidence are still found from previous studies related to the comparison between endoscopic and surgical approaches.The availability of experienced operator and resources needs to be considered in creating individualized treatment strategies for managing difficult biliary stones.展开更多
CHARACTERISTICS OF BILIARY CALCULOUSDISEASES IN CHINA:THE CHANGING SCOPEDiseases of the biliary tract in China is complicatedwith the prevalence of primary infection of the bileduct system.In the middle of the 20th ce...CHARACTERISTICS OF BILIARY CALCULOUSDISEASES IN CHINA:THE CHANGING SCOPEDiseases of the biliary tract in China is complicatedwith the prevalence of primary infection of the bileduct system.In the middle of the 20th century,biliary infection,biliary parasitic infestation,andbiliary stones made up the three chief componentsof biliary diseases in China.As to the展开更多
目的探讨加速术后康复(enhanced recovery after surgery,ERAS)理念应用于微创肝切除术治疗肝内胆管结石肝萎缩病人围手术期的临床价值。方法回顾性队列研究分析青岛市市立医院肝胆外科2016年12月至2023年3月通过腹腔镜下肝切除术治疗...目的探讨加速术后康复(enhanced recovery after surgery,ERAS)理念应用于微创肝切除术治疗肝内胆管结石肝萎缩病人围手术期的临床价值。方法回顾性队列研究分析青岛市市立医院肝胆外科2016年12月至2023年3月通过腹腔镜下肝切除术治疗的63例肝内胆管结石肝萎缩病人的临床资料,根据围手术期处理方法不同将其分为ERAS组(32例)和对照组(常规组,31例)。比较分析ERAS理念对病人术中情况(手术时间及术中出血量)、住院费用、术后肝功能、康复时间及并发症等指标的影响。呈偏态分布的计量资料以M(Q1,Q3)表示,采用秩和检验。结果ERAS组与对照组比较,病人术后康复时间明显缩短[6.0(5.0,7.0)d比8.0(5.0,9.0)d,P<0.01],住院费用更少[46531(38676,51311)元比55553(47638,65529)元,P<0.01],并发症发生率更低[31.3%(10/32)比93.5%(29/31),P<0.01],术后留置T管率更低[28.1%(9/32)比58.1%(18/31),P<0.01];两组病人在手术时间、出血量以及术后1 d、3 d的血谷丙转氨酶、谷草转氨酶、C反应蛋白及预后营养指数方面差异均无统计学意义(均P>0.05)。结论ERAS理念应用于肝切除治疗肝胆管结石肝萎缩的围手术期管理是安全有效的,有助于病人的快速安全康复,值得在肝内胆管结石肝切除术中推广。展开更多
目的 在胆总管取石术后使用100 mL的0.9%氯化钠注射液冲洗胆总管,观察是否能提高残石的清除率。方法 纳入该院接受内镜逆行胰胆管造影术(ERCP)联合碎石术的胆总管结石(≥12 mm)患者112例,对取石后胆总管造影显示结石完全清除者,行管腔...目的 在胆总管取石术后使用100 mL的0.9%氯化钠注射液冲洗胆总管,观察是否能提高残石的清除率。方法 纳入该院接受内镜逆行胰胆管造影术(ERCP)联合碎石术的胆总管结石(≥12 mm)患者112例,对取石后胆总管造影显示结石完全清除者,行管腔内超声检查术(IDUS),观察有无胆总管残石。根据IDUS下所观察到的残石数量来确定评分:大量结石碎片为1分;少量结石碎片为2分;完全清除为3分。分别在ERCP清除胆总管结石,以及用50 mL和100 mL 0.9%氯化钠注射液冲洗后,行IDUS检查,并对结石数量进行评分。结果 取石术后未予以0.9%氯化钠注射液进行胆总管冲洗时,所有患者均未达到3分;经50 mL 0.9%氯化钠注射液冲洗后,有45例(40.18%)患者评分为3分;经100 mL 0.9%氯化钠注射液冲洗后,有99例(88.39%)患者评分为3分。多因素Logistic回归分析显示,胆总管直径> 15 mm (OR=4.90,95%CI:1.19~22.57,P=0.013)、胆总管角度(胆总管造影中胆总管的轴线与胆总管壶腹轴线之间的成角)≤140°(OR=6.92,95%CI:1.83~38.98,P=0.047)及十二指肠憩室(OR=4.10,95%CI:1.14~16.90,P=0.041)是使用100 mL 0.9%氯化钠注射液冲洗失败的独立危险因素。结论 用100 mL 0.9%氯化钠注射液冲洗胆道,可有效清除碎石术后胆总管残石。展开更多
目的:分析腹腔镜与内镜联合治疗对胆囊结石伴胆管结石患者的影响。方法:选取2022年5月—2023年5月贵州医科大学附属白云医院收治的70例胆囊结石伴胆管结石患者作为研究对象。根据随机数表法将其分为对照组和观察组,各35例。对照组给予...目的:分析腹腔镜与内镜联合治疗对胆囊结石伴胆管结石患者的影响。方法:选取2022年5月—2023年5月贵州医科大学附属白云医院收治的70例胆囊结石伴胆管结石患者作为研究对象。根据随机数表法将其分为对照组和观察组,各35例。对照组给予传统手术治疗,观察组给予腹腔镜与内镜联合治疗。比较两组术前、术后3 d疼痛情况及生活质量,围手术期指标及术后并发症。结果:术后3 d,观察组视觉模拟评分法(visual analogue scale,VAS)评分低于对照组,简明生活质量量表(the MOS item short form 36 health survey,SF-36)评分高于对照组,差异有统计学意义(P<0.05)。观察组术中出血量少于对照组,术后首次排气时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。两组术后并发症发生率比较,差异无统计学意义(P>0.05)。结论:腹腔镜与内镜联合治疗胆囊结石伴胆管结石的效果显著,具有疼痛轻、术中出血量少、术后恢复快等优点,从而能提升患者生活质量。展开更多
基金Supported by Chang Gung Memorial Hospital,No. CMRPG300011
文摘AIM:To detect and manage residual common bile duct(CBD)stones using ultraslim endoscopic peroral cholangioscopy(POC)after a negative balloon-occluded cholangiography.METHODS:From March 2011 to December 2011,a cohort of 22 patients with CBD stones who underwent both endoscopic retrograde cholangiography(ERC)and direct POC were prospectively enrolled in this study.Those patients who were younger than 20 years of age,pregnant,critically ill,or unable to provide informed consent for direct POC,as well as those with concomitant gallbladder stones or CBD with diameters less than 10 mm were excluded.Direct POC using an ultraslim endoscope with an overtube balloon-assisted technique was carried out immediately after a negative balloon-occluded cholangiography was obtained.RESULTS:The ultraslim endoscope was able to be advanced to the hepatic hilum or the intrahepatic bile duct(IHD)in 8 patients(36.4%),to the extrahepatic bile duct where the hilum could be visualized in 10 patients(45.5%),and to the distal CBD where the hilum could not be visualized in 4 patients(18.2%).The procedure time of the diagnostic POC was 8.2 ± 2.9 min(range,5-18 min).Residual CBD stones were found in 5(22.7%)of the patients.There was one residual stone each in 3 of the patients,three in 1 patient,and more than five in 1 patient.The diameter of the residual stones ranged from 2-5 mm.In 2 of the patients,the residual stones were successfully extracted using either a retrieval balloon catheter(n = 1)or a basket catheter(n = 1)under direct endoscopic control.In the remaining 3 patients,the residual stones were removed using an irrigation and suction method under direct endoscopic visualization.There were no serious procedure-related complications,such as bleeding,pancreatitis,biliary tract infection,or perforation,in this study.CONCLUSION:Direct POC using an ultraslim endoscope appears to be a useful tool for both detecting and treating residual CBD stones after conventional ERC.
文摘Common bile duct(CBD)stone is a common biliary problem,which often requires endoscopic approach as the initial treatment option.Roughly,7%-12%of the subjects who experience cholecystectomy were subsequently referred to biliary endoscopist for further management.In general,there are three classifications of difficult CBD stone,which are based on the characteristics of the stone(larger than 15 mm,barrel or square-shaped stones,and hard consistency),accessibility to papilla related to anatomical variations,and other clinical conditions or comorbidities of the patients.Currently,endoscopic papillary large balloon dilation(EPLBD)of a previous sphincterotomy and EPLBD combined with limited sphincterotomy performed on the same session is still recommended by the European Society of Gastrointestinal Endoscopy as the main approach in difficult CBD stones with history of failed sphincterotomy and balloon and/or basket attempts.If failed extraction is still encountered,mechanical lithotripsy or cholangioscopy-assisted lithotripsy or extracorporeal shockwave lithotripsy can be considered.Surgical approach can be considered when stone extraction is still failed or the facilities to perform lithotripsy are not available.To our knowledge,conflicting evidence are still found from previous studies related to the comparison between endoscopic and surgical approaches.The availability of experienced operator and resources needs to be considered in creating individualized treatment strategies for managing difficult biliary stones.
文摘CHARACTERISTICS OF BILIARY CALCULOUSDISEASES IN CHINA:THE CHANGING SCOPEDiseases of the biliary tract in China is complicatedwith the prevalence of primary infection of the bileduct system.In the middle of the 20th century,biliary infection,biliary parasitic infestation,andbiliary stones made up the three chief componentsof biliary diseases in China.As to the
文摘目的 在胆总管取石术后使用100 mL的0.9%氯化钠注射液冲洗胆总管,观察是否能提高残石的清除率。方法 纳入该院接受内镜逆行胰胆管造影术(ERCP)联合碎石术的胆总管结石(≥12 mm)患者112例,对取石后胆总管造影显示结石完全清除者,行管腔内超声检查术(IDUS),观察有无胆总管残石。根据IDUS下所观察到的残石数量来确定评分:大量结石碎片为1分;少量结石碎片为2分;完全清除为3分。分别在ERCP清除胆总管结石,以及用50 mL和100 mL 0.9%氯化钠注射液冲洗后,行IDUS检查,并对结石数量进行评分。结果 取石术后未予以0.9%氯化钠注射液进行胆总管冲洗时,所有患者均未达到3分;经50 mL 0.9%氯化钠注射液冲洗后,有45例(40.18%)患者评分为3分;经100 mL 0.9%氯化钠注射液冲洗后,有99例(88.39%)患者评分为3分。多因素Logistic回归分析显示,胆总管直径> 15 mm (OR=4.90,95%CI:1.19~22.57,P=0.013)、胆总管角度(胆总管造影中胆总管的轴线与胆总管壶腹轴线之间的成角)≤140°(OR=6.92,95%CI:1.83~38.98,P=0.047)及十二指肠憩室(OR=4.10,95%CI:1.14~16.90,P=0.041)是使用100 mL 0.9%氯化钠注射液冲洗失败的独立危险因素。结论 用100 mL 0.9%氯化钠注射液冲洗胆道,可有效清除碎石术后胆总管残石。
文摘目的:分析腹腔镜与内镜联合治疗对胆囊结石伴胆管结石患者的影响。方法:选取2022年5月—2023年5月贵州医科大学附属白云医院收治的70例胆囊结石伴胆管结石患者作为研究对象。根据随机数表法将其分为对照组和观察组,各35例。对照组给予传统手术治疗,观察组给予腹腔镜与内镜联合治疗。比较两组术前、术后3 d疼痛情况及生活质量,围手术期指标及术后并发症。结果:术后3 d,观察组视觉模拟评分法(visual analogue scale,VAS)评分低于对照组,简明生活质量量表(the MOS item short form 36 health survey,SF-36)评分高于对照组,差异有统计学意义(P<0.05)。观察组术中出血量少于对照组,术后首次排气时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。两组术后并发症发生率比较,差异无统计学意义(P>0.05)。结论:腹腔镜与内镜联合治疗胆囊结石伴胆管结石的效果显著,具有疼痛轻、术中出血量少、术后恢复快等优点,从而能提升患者生活质量。
