气象观测场在汽车试验场中的应用研究

汽车试验场作为汽车开展道路测试的重要场所,用于验证汽车产品的品质以及可靠性。除了场地道路外,气象条件作为汽车道路测试的重要一环,在《GB/T12534-1990汽车道路试验方法通则》中也有明确要求,如:试验时应是无雨无雾天气,相对湿度小于95%,气温0-40℃,风速不大于3m/s。同时气象条件也作为试验场道路管控的重要依据,实时风速、雨量、能见度等信息为场地管理者发布限速、限行、封场等通知提供必要参考依据,直接影响道路测试安全管控的及时性。因此,文章从气象观测场的建设、气象服务、异常天气道路管控等方面开展气象观测场在汽车试验场中的应用研究。

Cyber Resilience through Real-Time Threat Analysis in Information Security

This paper examines how cybersecurity is developing and how it relates to more conventional information security. Although information security and cyber security are sometimes used synonymously, this study contends that they are not the same. The concept of cyber security is explored, which goes beyond protecting information resources to include a wider variety of assets, including people [1]. Protecting information assets is the main goal of traditional information security, with consideration to the human element and how people fit into the security process. On the other hand, cyber security adds a new level of complexity, as people might unintentionally contribute to or become targets of cyberattacks. This aspect presents moral questions since it is becoming more widely accepted that society has a duty to protect weaker members of society, including children [1]. The study emphasizes how important cyber security is on a larger scale, with many countries creating plans and laws to counteract cyberattacks. Nevertheless, a lot of these sources frequently neglect to define the differences or the relationship between information security and cyber security [1]. The paper focus on differentiating between cybersecurity and information security on a larger scale. The study also highlights other areas of cybersecurity which includes defending people, social norms, and vital infrastructure from threats that arise from online in addition to information and technology protection. It contends that ethical issues and the human factor are becoming more and more important in protecting assets in the digital age, and that cyber security is a paradigm shift in this regard [1].

Factors Influencing the Emergency Medical Service Response Time for Cardiovascular Disease in Guangzhou, China

While emergency medical service (EMS) response time (ERT) is a major factor associated with the survival of patients with cardiovascular disease (CVD), relatively few studies have explored the factors associated with ERT. This study aimed to assess the current status of ERT and to identify the factors affecting ERT in patients with CVD in China. Between January 1, 2011 and December 31, 2015, EMS responses to CVD incidents in Guangzhou, China, were examined. The primary outcome was ERT, defined as the time from receipt of an emergency call to the arrival of paramedics on the scene. Factors associated with ERT were evaluated by multivariable logistic regression. A total of 44 383 CVD incidents were analysed. The median ERT was 12.58 min (interquartile range=9.98-15.67). Among the risk factors, distance (OR=13.73, 95% CI=11.76- 16.04), level of hospital (OR=1.57, 95% CI=1.40-1.75), and site of the incident (OR=1.53, 95% CI=1.38-1.69) were the top three significant factors affecting the ERT. Our results suggest that greater attention should be given to factors affecting the ERT. It is essential to make continuous efforts to promote the development of effective interventions to reduce the response time.

Dielectric Analysis of Response Time in Electrorheological Fluids Developed for Medical Devices

Three electrorheological fluids (ERFs) of recently synthesized Polyaniline.HCl and Cellulose fluids as well as a commercial product from Fludicon? (Germany), were evaluated with a two-electrode probe unit and by Dielectric Analysis (DEA). The study was a part of an ongoing medical device development project. The dielectric response times were calculated using the critical peak frequency in a corresponding Debye plot of Tan Delta (loss factor/permittivity) vs. log frequency. The DEA revealed the response times (tau, τ) in ms. The Fludicon? ERF was DEA durable (repeat cycles produced same results) and the τ was temperature dependent: 16 ms at 25°C and 0.16 ms at 80°C. The Cellulose ERF was somewhat DEA durable and the τ was 5.5 ms at 25°C and 0.21 ms at 80°C. The response times were logarithmic with the temperature (°C) with a correlation coefficient of >0.98 for the Cellulose and Fludicon? ERFs. The Polyaniline ERF had a τ of 53 ms at 25°C in the 1st DEA run and there was no indication of a τ for the remaining DEA tests.

NetIQ AppManager中的Response Time技术(2)

3.12 AppManager Response Time for Lotus Notes 对于Lotus Notes的用户而言（Lotus Domino服务器的客户端）,只需要很少的AppManager脚本就可以跟踪用户至上的响应。由于Lotus Notes中大多数的对象都是文档,因此通过使用少量的文档脚本,就可以很容易组成有代表性的客户端操作以便进行性能和可用性监测。

A GIS-Based Decision Support System for Reducing Air Ambulance Response Times: A Case Study on Public Schools in Jeddah City

In injuries reducing ambulance response time (time from injury to hospital arrival) is an important factor for saving people’s lives. Helicopter emergency medical services can reduce out-of-hospital transport times because of their high speed and their ability to travel in straight paths?unlike ground ambulance which are restricted to road network paths, as well as the ability toaccess rural or remote area injuries that are difficult to reach by ground ambulance. GIS technology aids air ambulance movement planning to reduce out-of-hospital response time based on mathematical and geographic models to support decision making which is necessary from out-of-hospital care providers. The goal of this study is to use GIS to develop an efficient DSS to outline where air ambulance can reduce response times, by using spatial analysis tools to create Euclidean distance and direction zones around receiving hospitals. The study concludes that GIS technology can be used to develop an efficient DSS to outline where air ambulance can reduce response times, by creating surfaces of Euclidean allocation, direction, and distance that can be used to improve initial response times for the civil defense air rescue and air ambulance services.

Analysis of response time probability distribution of workflows

An evaluation approach for the response time probability distribution of workflows based on the fluid stochastic Petri net formalism is presented. Firstly, some problems about stochastic workflow net modeling are discussed. Then how to convert a stochastic workflow net model into a fluid stochastic Petri net model is described. The response time distribution can be obtained directly upon the transient state solution of the fluid stochastic Petri net model. In the proposed approach, there are not any restrictions on the structure of workflow models, and the processing times of workflow tasks can be modeled by using arbitrary probability distributions. Large workflow models can be efficiently tackled by recursively using a net reduction technique.

A retrospective view on the history of natural sciences in XX-XXI

The presented paper is dedicated to a new ret-rospective view on the history of natural sci-ences in XX-XXI cc, partially including the sci-ence philosophy (mainly, the problems of the scientific realism, i.e. the correspondence of science to reality) and also a novel scheme for different classes of sciences with different ob-jects and paradigms. There are analyzed the chosen “great” and “grand” problems of phys-ics (including the comprehension of quantum mechanics, with a recently elaborated new chapter, connected with time as a quantum obs- ervable and time analysis of quantum processes) and also of natural sciences as a whole. The particular attention is paid to the interpretation questions and slightly to the aspects, inevitably connected with the world- views of the res- earchers (which do often constitute a part of the interpretation questions).

Fork-Join program response time on multiprocessors with exchangeable join

The Fork-Join program consisting of K parallel tasks is a useful model for a large number of computing applications. When the parallel processor has multi-channels, later tasks may finish execution earlier than their earlier tasks and may join with tasks from other programs. This phenomenon is called exchangeable join (EJ), which introduces correlation to the task’s service time. In this work, we investigate the response time of multiprocessor systems with EJ with a new approach. We analyze two aspects of this kind of systems: exchangeable join (EJ) and the capacity constraint (CC). We prove that the system response time can be effectively reduced by EJ, while the reduced amount is constrained by the capacity of the multiprocessor. An upper bound model is constructed based on this analysis and a quick estimation algorithm is proposed. The approximation formula is verified by extensive simulation results, which show that the relative error of approximation is less than 5%.

Analysis of Waste-Rock Transportation Process Performance in an Open-Pit Mine Based on Statistical Analysis of Cycle Times Data

In this paper, the performance of a waste rock transportation process in an open pit mine was assessed by using cycle time data. A computerized truck-excavator dispatch system was used to record the cycle times. The process was broken into seven steps (or components of the total cycle), durations of which were recorded for a period of 1 month, leading to N = 60,690 data points or dispatches. The open pit mine studied consisted of 12 waste types loaded by 14 excavators and hauled by 49 trucks (at a trucks-to-excavator ratio of 3.5:1) in 75 changing locations. The string-type data was coded using integers to allow a FORTRAN code to extract process performance parameters using statistical analysis. The study established a wide range of parameters including: the waste material generation rate (about 1.73 million t/month, 81% comprising waste rock), truck fill factor, f, total cycle time (Tct), production capacity, theoretical cycle time, non-productive cycle time Tnp, and cycle time performance ratio (CTPR), denoted as Tpr. The factors affecting the process performance include: truck model, excavator model, location (haul distance and road conditions) and material type. For a fixed material type and tonnage, the PDFs of the cycle time components were logarithmic in nature, capable of differentiating performance variations under different factors. It was concluded that the performance of the waste material transportation system in this mine was determined to be acceptable due to mean value of Tpr = 2.432 being closer to unity. Reduction measures were suggested to minimize the cycle time for the process bottlenecks determined from Pareto analysis (that is, full haul, empty haul and loading processes).

Everything Is Timelessly Connected: Metaphysics, Physics, Consciousness, Spacetime Travel, DNA, and the Dry Bones Prophesy (Ezekiel Ch. 37)

This paper provides a perception that all things are connected. Starting with the perception of Metaphysics and how matter exists out of total void, complementary matter, or dark matter, the incompleteness of Einstein relativistic theory. Multi spacetime universes and the jump drive for jumping within and between spacetime universes. Warp drive for space travel. DNA as sequence of momentary frequencies and how it related to Ezekiel’s dry bones prophecy. The outcome of neural patterns as cords of consciousness, consciousness as the collection of all cords of consciousness and the lack of uniqueness of individual consciousness. Finally, all things are cords of consciousness.

Investigation of Excavator Performance Factors in an Open-Pit Mine Using Loading Cycle Time

This study presents the effect of excavator model, loading operation location, shift availability and truck-shovel combination on loading cycle time and productivity of an open-pit mine. The loading cycle time was used to assess the material loading system performance which is one of the key components of the total cycle time for material transportation in an open-pit mine. Loading is among the components of cycle time during which material is being handled. The data analyzed?was?collected from a computerized dispatch system at GGM from which 62,000 loading dispatches per month involving several shifts, 14 excavators and 49 trucks were loaded. About 4465 dispatches per excavator and 1276 dispatches per truck were assessed using loading cycle time data for each dispatch for a period of four months (between August and December). Under fixed tonnage loaded and waste type (33 t of non-acid forming waste rock),?it was observed that loading cycle time depends on excavator model, location and truck being loaded. Average cycle times, PDFS?and CDFS of loading cycle time series were used to identify differences in performance under different situations. It was concluded that shift availability for excavators, loading location, excavator model and truck-shovel combinations strongly affect the productivity during loading process in an open-pit mine.

An Improved Text-Based and Image-Based CAPTCHA Based on Solving and Response Time

CAPTCHA is an acronym that stands for Completely Automated Public Turing Test to tell Computers and Humans Apart(CAPTCHA),it is a good example of an authentication system that can be used to determine the true identity of any user.It serves as a security measure to prevent an attack caused by web bots(automatic programs)during an online transaction.It can come as text-based or image-based depending on the project and the programmer.The usability and robustness,as well as level of security,provided each of the varies and call for the development of an improved system.Hence,this paper studied and improved two different CAPTCHA systems(the text-based CAPTCHA and image-based CAPTCHA).The textbased and image-based CAPTCHAwere designed using JavaScript.Response time and solving time are the two metrics used to determine the effectiveness and efficiency of the two CAPTCHA systems.The inclusion of response time and solving time improved the shortfall of the usability and robustness of the existing system.The developed system was tested using 200 students from the Federal College of Animal Health and Production Technology.The results of each of the participants,for the two CAPTCHAs,were extracted from the database and subjected to analysis using SPSS.The result shows that textbased CAPTCHAhas the lowest average solving time(21.3333 s)with a 47.8%success rate while image-based CAPTCHA has the highest average solving time was 23.5138 s with a 52.8%success rate.The average response time for the image-based CAPTCHA was 2.1855 s with a 37.9%success rate lower than the text-based CAPTCHA response time(3.5561 s)with a 62.1%success rate.This indicates that the text-based CAPTCHA is more effective in terms of usability tests while image-based CAPTCHA is more efficient in terms of system responsiveness and recommended for potential users.

The Response Time Analysis of Digital Broadcasting System

Digital broadcasting system has become a high-light of research on computer application. To respond to the changes of the playbill in the broadcasting system in real time, the response time of the system must be studied. There is scarcely the research on this area currently. The influence factors in the response time are analyzed; the model on the response time of the system service is built; how the influence factors affect the response time of the system service is validated; and four improvement measures are proposed to minimize the response time of system service.

Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°C.We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort.Plasma samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline project.These samples were stored at-80°C for up to 6 years before being used in this study.Our results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage time.However,the level of total tau showed a negative correlation with sample storage time.Notably,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage time.This was not observed in individuals with cognitive impairment.Consequently,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time.Therefore,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's disease.Furthermore,in cohort studies,it is important to consider the impact of storage time on the overall results.

Consideration of Viscoelasticity in Time Step FEM-Based Restraint Analyses of Hardening Concrete

Concrete structures may suffer considerable restraint stresses during their hardening period. This is caused by several deformation impacts, especially temperature field changings due to hydration heat and volume changes due to autogenous shrinkage. Mainly affected are massive concrete members, but also the application of new concrete types or the erection of outstanding constructions requires further investigations in this context. 3D-FEM analyses of hydration heat induced temperature development in combination with the well known shrinkage give sufficient results for the deformation impact. The according elastic restraint stresses can be determined with consideration of the concrete’s rising elastic modulus and the restraint degree of the system. But due to duration of the heat flow process, the height of restraint stresses is strongly dependent from the viscoelasticity of the concrete. The viscoelastic effects consist of many components constituted by changing material properties influencing themselves. In practice, different simplified approaches are available for considering this in calculations. Their implementation in time step analyses is not generally admitted and requires expertise. In contrast, present research develops material models needing specific input parameters for every use case. This contribution focuses on a practicable approach considering the superposition of the viscoelastic behaviour of every stress increment in time step FEM analysis. The differentiation between the pure viscoelastic material behaviour (as it is given in the codes for idealistic conditions like creep or relaxation) and the according viscoelastic system response (addicted to the systems variable restraint degree) allows the transfer of this model into practice. As one application example of this approach, the compatibility check and the FEM-based recalculation of the monitoring program of a massive power plant slab will be presented.

Knowledge Management of Software Productivity and Development Time

In this paper, we identify a set of factors that may be used to forecast software productivity and software development time. Software productivity was measured in function points per person hours, and software development time was measured in number of elapsed days. Using field data on over 130 field software projects from various industries, we empirically test the impact of team size, integrated computer aided software engineering (ICASE) tools, software development type, software development platform, and programming language type on the software development productivity and development time. Our results indicate that team size, software development type, software development platform, and programming language type significantly impact software development productivity. However, only team size significantly impacts software development time. Our results indicate that effective management of software development teams, and using different management strategies for different software development type environments may improve software development productivity.

Surge Response of a Compliant Offshore Structure by Time Domain Simulation

A single-degree-of-freedom equation of motion was used for modeling a compliant offshore structure exposed to viscous hydrodynamic loads. The equation of motion contains nonlinearities in the forms of both Duffing stiffness and Morison drag force with current. The water particle velocity and acceleration for calculating the Morison inertia and drag forces are modeled as Gaussian processes based on a Pierson-Moskowitz (P-M) elevation spectrum. The single-degree-of-freedom equation of motion containing different ocean current values are then numerically integrated via a fourth-order Runge-Kutta scheme. Time trajectories of the surge response displacements of the offshore structure and the response probability density curves are obtained. Furthermore, the ocean current influences on the response central moments up to the fourth order are studied. A literature review reveals that this is the first treatment of such a pair of nonlinearities in time domain. The simulation results are analyzed, and some conclusions valuable for engineering design are pointed out.

Sustained complete response to erlotinib in squamous cell carcinoma of the head and neck:A case report

BACKGROUND Squamous cell carcinoma of head and neck(SCCHN) is the fifth most common cancer worldwide. Inhibition of epidermal growth factor receptor signaling has been shown to be a critical component of therapeutic option. Herein, we report a case of durable complete response to erlotinib.CASE SUMMARY An 81-year-old Caucasian male who presented with metastatic poorly differentiated squamous cell carcinoma of right cervical lymph nodes(levels 2 and 3). Imaging studies including(18)F-fluorodeoxyglucose positron emission tomography/computed tomography(CT) and contrast-enhanced CT scan of neck and chest did not reveal any other disease elsewhere. Panendoscopic examination with random biopsy did not reveal malignant lesion in nasopharynx,oropharynx, and larynx. He underwent modified neck dissection and postoperative radiation. Within 2 mo after completion of radiation, he developed local recurrence at right neck, which was surgically removed. Two mo after the salvage surgery, he developed a second recurrence at right neck. Due to suboptimal performance status and his preference, he started erlotinib treatment.He achieved partial response after first 2 mo of erlotinib treatment, then complete response after total 6 mo of erlotinib treatment. He developed sever skin rash and diarrhea including Clostridium difficile infection during the course of erlotinib treatment requiring dose reduction and eventual discontinuation. He remained in complete remission for more than two years after discontinuation of erlotinib.CONCLUSION We report a case of metastatic SCCHN achieving durable complete response from erlotinib. Patient experienced skin rash and diarrhea toxicities which were likely predictors of his treatment response.

Research on Estimation of Time Delay Difference in Passive Locating for Impulse Signal

Analyzed the relation between time delay difference and time delay estimation errors, based on the principles of three-point locating, a reformed threshold method for time delay difference estimation of impulse signals, called as amendment estimation for short, is developed by introducing channel equalization technique to its conventional version, named as direct estimation in this paper, to improve the estimation stability. After inherent relationship between time delay and phase shift of signals is analyzed, an integer period error compensation method utilized the diversities of both contribution share and contribution mode of concerned estimates is proposed under the condition of high precision phase lag estimation. Finally, a cooperative multi-threshold estimation method composed of amendment and direct estimations to process impulse signals with three thresholds is established. In sea trials data tests of passive locating, this method improves the estimation precision of time delay difference efficiently. The experiments verify the theoretical predictions.