The experimental results showed that the duration of microbial retting processing of kenaf fibers by using aerobic microbe was four times shorter than that by using anaerobic microbe. The residual gum percentage,break...The experimental results showed that the duration of microbial retting processing of kenaf fibers by using aerobic microbe was four times shorter than that by using anaerobic microbe. The residual gum percentage,breaking strength, breaking elongation and linear density of aerobic retted kenaf bundle fibers did not show significantly difference with that of anaerobic retted kenaf bundle fibers by ANOVA-Tukey's studentized test at a = 5% except for the softness. The bioenergetic principle and the calculation of the amount of ATP produced during the decomposition processing of kenaf gums were used to explain why the retting duration in the case of using aerobic microbes was much shorter than that of using anaerobic microbes.展开更多
The performance of UASB (Up-flow Anaerobic Sludge Blanket) reactor was investigated in the present study for treatment of flax retting wastewater. Batch and continuous experiments on a pilot scale were designed. The i...The performance of UASB (Up-flow Anaerobic Sludge Blanket) reactor was investigated in the present study for treatment of flax retting wastewater. Batch and continuous experiments on a pilot scale were designed. The initial seed for granules (bacteria acclimation) formed earlier was from municipal sewage treatment plant with VSS of 18 - 20 g/L. Batch experiments proved that the sludge retention time (SRT) was 77 days. Under steady state conditions, continuous experiments were conducted at organic loading rates (OLRs) in the range of 1.2 to8.6 kgCODs m–3·d–1, where the hy- draulic retention time (HRT) decreased from 72 to 12 hrs. The results proved that the UASB technology provides good COD removal efficiency from 64.5% to 90.5% as COD loading rate decreased and good biogas production at proper food: micro-organism (F:M) ratios.展开更多
BACKGROUND Multiple endocrine neoplasia type 2(MEN2)is a rare,autosomal dominant endocrine disease.Currently,the RET proto-oncogene is the only gene implicated in MEN2A pathogenesis.Once an RET carrier is detected,fam...BACKGROUND Multiple endocrine neoplasia type 2(MEN2)is a rare,autosomal dominant endocrine disease.Currently,the RET proto-oncogene is the only gene implicated in MEN2A pathogenesis.Once an RET carrier is detected,family members should be screened to enable early detection of medullary thyroid carcinoma,pheochromocytoma,and hyperparatitity.Among these,medullary thyroid carcinoma is the main factor responsible for patient mortality.Accordingly,delineating strategies to inform clinical follow-up and treatment plans based on genes is paramount for clinical practitioners.CASE SUMMARY Herein,we present RET proto-oncogene mutations,clinical characteristics,and treatment strategies in a family with MEN2A.A family study was conducted on patients diagnosed with MEN2A.DNA was extracted from the peripheral blood of family members,and first-generation exon sequencing of the RET protooncogene was conducted.The C634Y mutation was identified in three family members spanning three generations.Two patients were sequentially diagnosed with pheochromocytomas and bilateral medullary thyroid carcinomas.A 9-yearold child harboring the gene mutation was diagnosed with medullary thyroid carcinoma.Surgical resection of the tumors was performed.All family members were advised to undergo complete genetic testing related to the C634Y mutation,and the corresponding treatments administered based on test results and associated clinical guidelines.CONCLUSION Advancements in MEN2A research are important for familial management,assessment of medullary thyroid cancer invasive risk,and deciding surgical timing.展开更多
Volatile organic compounds(VOC)gas detection devices based on semiconductor sensors have become a common method due to their low cost,simple principle,and small size.However,with the continuous development of material...Volatile organic compounds(VOC)gas detection devices based on semiconductor sensors have become a common method due to their low cost,simple principle,and small size.However,with the continuous development of materials science,various new materials have been applied in the fabrication of gas sensors,but these new materials have more stringent requirements for operating temperature,which cannot be met by existing sensor modules on the market.Therefore,this paper proposes a temperature-adjustable sensor module and designs an environmental monitoring system based on the STM32F103RET6 microprocessor.This system primarily utilizes multiple semiconductor gas sensors to monitor and record the concentrations of various harmful gases in different environments.It can also monitor real-time temperature,humidity,and latitude and longitude in the current environment,and upload the data to the Internet of Things via 4G communication.This system has the advantages of small size,portability,and low cost.Experimental results show that the sensor module can achieve precise control of operating temperature to a certain extent,with an average temperature error of approximately 3%.The monitoring system demonstrates a certain level of accuracy in detecting target gases and can promptly upload the data to a cloud platform for storage and processing.A comparison with professional testing equipment shows that the sensitivity curves of each sensor exhibit similarity.This study provides engineering and technical references for the application of VOC gas sensors.展开更多
BACKGROUND Multiple primary colorectal carcinoma(MPCC)is a rare clinical disease,which is challenging to differentiate from metastatic disease using histopathological methods.Next-generation sequencing(NGS)has been em...BACKGROUND Multiple primary colorectal carcinoma(MPCC)is a rare clinical disease,which is challenging to differentiate from metastatic disease using histopathological methods.Next-generation sequencing(NGS)has been employed to identify multiple primary cancers.CASE SUMMARY This study a rare case of a 63-year-old male patient diagnosed with MPCC by targeted NGS,which was initially missed by radiological evaluation.The patient was found to have two tumors located on the surface of the colorectum which had distinct genomic alterations.Based on wild-type KRAS detected in the unresected tumor,the patient benefited from the epidermal growth factor receptor(EGFR)inhibitor cetuximab treatment,but developed novel mutations including KIF5B-RET fusion,which provides a possible resistance mechanism to anti-EGFR therapy.CONCLUSION Our case highlights the necessity of using genetic testing for primary tumor diagnosis and the application of serial plasma circulating tumor DNA profiling for dynamic disease monitoring.展开更多
Introduction: Central serous chorioretinopathy (CSCR) is associated with serous sensorineural retinal detachment in the macular region. The condition that affects the male gender more than their female counterpart res...Introduction: Central serous chorioretinopathy (CSCR) is associated with serous sensorineural retinal detachment in the macular region. The condition that affects the male gender more than their female counterpart results from focal leakage disturbance of retinal pigment epithelial cells and choroidal abnormalities. The corticosteroid is highlighted as one of the major factors that promote the occurrence of CSCR. Stress and pregnancy, especially in the third trimester, have also been reported by some authors. Central serous chorioretinopathy associated with pregnancy complicated by retroplacental hematoma is a rare event. Observation: We report the case of a pregnant woman at approximately 34 weeks of amenorrhea who presented a sudden and severe drop in visual acuity on a pregnancy complicated by retroplacental hematoma and delivered by cesarean section. The diagnosis was based on clinical arguments associated with photos of the retina made by the MII Ret Cam device (Made In India, Retinoscope Camera) highlighting the lifting of the macular region. Ophthalmological monitoring without medical or physical treatment was instituted. At two months of progression without treatment, bilateral visual acuity was 10/10. Conclusion: Central serous chorioretinopathy and pregnancy is not unusual;however, its bilateral and brutal form in a context of pregnancy complicated by retroplacental hematoma is rare. Despite this favorable evolution, monitoring remains necessary in order to prevent recurrences and complications.展开更多
文摘The experimental results showed that the duration of microbial retting processing of kenaf fibers by using aerobic microbe was four times shorter than that by using anaerobic microbe. The residual gum percentage,breaking strength, breaking elongation and linear density of aerobic retted kenaf bundle fibers did not show significantly difference with that of anaerobic retted kenaf bundle fibers by ANOVA-Tukey's studentized test at a = 5% except for the softness. The bioenergetic principle and the calculation of the amount of ATP produced during the decomposition processing of kenaf gums were used to explain why the retting duration in the case of using aerobic microbes was much shorter than that of using anaerobic microbes.
文摘The performance of UASB (Up-flow Anaerobic Sludge Blanket) reactor was investigated in the present study for treatment of flax retting wastewater. Batch and continuous experiments on a pilot scale were designed. The initial seed for granules (bacteria acclimation) formed earlier was from municipal sewage treatment plant with VSS of 18 - 20 g/L. Batch experiments proved that the sludge retention time (SRT) was 77 days. Under steady state conditions, continuous experiments were conducted at organic loading rates (OLRs) in the range of 1.2 to8.6 kgCODs m–3·d–1, where the hy- draulic retention time (HRT) decreased from 72 to 12 hrs. The results proved that the UASB technology provides good COD removal efficiency from 64.5% to 90.5% as COD loading rate decreased and good biogas production at proper food: micro-organism (F:M) ratios.
基金Supported by The Finance Bureau of Dongguan City,Guangdong Province.
文摘BACKGROUND Multiple endocrine neoplasia type 2(MEN2)is a rare,autosomal dominant endocrine disease.Currently,the RET proto-oncogene is the only gene implicated in MEN2A pathogenesis.Once an RET carrier is detected,family members should be screened to enable early detection of medullary thyroid carcinoma,pheochromocytoma,and hyperparatitity.Among these,medullary thyroid carcinoma is the main factor responsible for patient mortality.Accordingly,delineating strategies to inform clinical follow-up and treatment plans based on genes is paramount for clinical practitioners.CASE SUMMARY Herein,we present RET proto-oncogene mutations,clinical characteristics,and treatment strategies in a family with MEN2A.A family study was conducted on patients diagnosed with MEN2A.DNA was extracted from the peripheral blood of family members,and first-generation exon sequencing of the RET protooncogene was conducted.The C634Y mutation was identified in three family members spanning three generations.Two patients were sequentially diagnosed with pheochromocytomas and bilateral medullary thyroid carcinomas.A 9-yearold child harboring the gene mutation was diagnosed with medullary thyroid carcinoma.Surgical resection of the tumors was performed.All family members were advised to undergo complete genetic testing related to the C634Y mutation,and the corresponding treatments administered based on test results and associated clinical guidelines.CONCLUSION Advancements in MEN2A research are important for familial management,assessment of medullary thyroid cancer invasive risk,and deciding surgical timing.
文摘Volatile organic compounds(VOC)gas detection devices based on semiconductor sensors have become a common method due to their low cost,simple principle,and small size.However,with the continuous development of materials science,various new materials have been applied in the fabrication of gas sensors,but these new materials have more stringent requirements for operating temperature,which cannot be met by existing sensor modules on the market.Therefore,this paper proposes a temperature-adjustable sensor module and designs an environmental monitoring system based on the STM32F103RET6 microprocessor.This system primarily utilizes multiple semiconductor gas sensors to monitor and record the concentrations of various harmful gases in different environments.It can also monitor real-time temperature,humidity,and latitude and longitude in the current environment,and upload the data to the Internet of Things via 4G communication.This system has the advantages of small size,portability,and low cost.Experimental results show that the sensor module can achieve precise control of operating temperature to a certain extent,with an average temperature error of approximately 3%.The monitoring system demonstrates a certain level of accuracy in detecting target gases and can promptly upload the data to a cloud platform for storage and processing.A comparison with professional testing equipment shows that the sensitivity curves of each sensor exhibit similarity.This study provides engineering and technical references for the application of VOC gas sensors.
文摘BACKGROUND Multiple primary colorectal carcinoma(MPCC)is a rare clinical disease,which is challenging to differentiate from metastatic disease using histopathological methods.Next-generation sequencing(NGS)has been employed to identify multiple primary cancers.CASE SUMMARY This study a rare case of a 63-year-old male patient diagnosed with MPCC by targeted NGS,which was initially missed by radiological evaluation.The patient was found to have two tumors located on the surface of the colorectum which had distinct genomic alterations.Based on wild-type KRAS detected in the unresected tumor,the patient benefited from the epidermal growth factor receptor(EGFR)inhibitor cetuximab treatment,but developed novel mutations including KIF5B-RET fusion,which provides a possible resistance mechanism to anti-EGFR therapy.CONCLUSION Our case highlights the necessity of using genetic testing for primary tumor diagnosis and the application of serial plasma circulating tumor DNA profiling for dynamic disease monitoring.
文摘Introduction: Central serous chorioretinopathy (CSCR) is associated with serous sensorineural retinal detachment in the macular region. The condition that affects the male gender more than their female counterpart results from focal leakage disturbance of retinal pigment epithelial cells and choroidal abnormalities. The corticosteroid is highlighted as one of the major factors that promote the occurrence of CSCR. Stress and pregnancy, especially in the third trimester, have also been reported by some authors. Central serous chorioretinopathy associated with pregnancy complicated by retroplacental hematoma is a rare event. Observation: We report the case of a pregnant woman at approximately 34 weeks of amenorrhea who presented a sudden and severe drop in visual acuity on a pregnancy complicated by retroplacental hematoma and delivered by cesarean section. The diagnosis was based on clinical arguments associated with photos of the retina made by the MII Ret Cam device (Made In India, Retinoscope Camera) highlighting the lifting of the macular region. Ophthalmological monitoring without medical or physical treatment was instituted. At two months of progression without treatment, bilateral visual acuity was 10/10. Conclusion: Central serous chorioretinopathy and pregnancy is not unusual;however, its bilateral and brutal form in a context of pregnancy complicated by retroplacental hematoma is rare. Despite this favorable evolution, monitoring remains necessary in order to prevent recurrences and complications.
