期刊文献+
共找到6篇文章
< 1 >
每页显示 20 50 100
A New Approach to Inducing Silicon Tethered Ring-closing Metathesis Reactions
1
作者 YANG Hong-li VAULTIER Miche 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2002年第4期414-418,共5页
Ring-closing metathesis reactions involving diallyldiphenylsilane and diallyloxydiphenylsilane were successfully performed by using only 0 01 mol or even less of Grubbs' catalyst 1. The effects of reaction parame... Ring-closing metathesis reactions involving diallyldiphenylsilane and diallyloxydiphenylsilane were successfully performed by using only 0 01 mol or even less of Grubbs' catalyst 1. The effects of reaction parameters, such as solvents, temperature and concentration of the catalyst are discussed. 展开更多
关键词 ring-closing metathesis reaction Grubbs' catalyst Diallyldiphenylsilane Diallyloxydiphenyl-silane
下载PDF
Modular Total Synthesis of (-)-Palmyrolide A and (+)-(5S,7S)-Palmyrolide A via Ring-Closing Metathesis and Alkene Isomerization 被引量:1
2
作者 Yecai Lai Wei-Min Dai 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2021年第1期69-74,共6页
A pentamodule assembly approach has been established for total synthesis of the naturally occurring(-)-palmyrolide A and(+)-5,7-epi-palmyrolide A.By using the racemic tert-butyl carbinol-containing alkyl iodide,the tw... A pentamodule assembly approach has been established for total synthesis of the naturally occurring(-)-palmyrolide A and(+)-5,7-epi-palmyrolide A.By using the racemic tert-butyl carbinol-containing alkyl iodide,the two diastereoisomeric macrolides could be obtained from the same sequence of reactions,demonstrating the flexibility of the multimodule assembly strategy for diverted total synthesis. 展开更多
关键词 ALKENE B-Alky Suzuki-Miyaura cross-coupling Modular total synthesis Cross coupling ring-closing metathesis
原文传递
Halogen Bond Catalysis on Carbonyl-Olefin Ring-Closing Metathesis Reaction:Comparison with Lewis Acid Catalysis
3
作者 Ying Li Yuanyuan Sun +2 位作者 Lingpeng Meng Qingzhong Li Yanli Zeng 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2022年第11期1275-1284,共10页
The carbonyl-olefin ring-closing metathesis reactions have become a powerful tool for carbon-carbon bond formation.In this work,the halogen bond catalysis and classical Lewis acid catalysis on the carbonyl-olefin ring... The carbonyl-olefin ring-closing metathesis reactions have become a powerful tool for carbon-carbon bond formation.In this work,the halogen bond catalysis and classical Lewis acid catalysis on the carbonyl-olefin ring-closing metathesis reaction were investigated by density function theory.For both the halogen bond catalysis and classical Lewis acid catalysis,the carbonyl-olefin ring-closing me-tathesis reaction occurs by[2+2]-cycloaddition process and[2+2]-cycloreversion process,the reaction energy barriers are low,there-fore,it can be performed easily at room temperature.The essential difference of the two kinds of catalysts is that the catalytic mecha-nism of halogen bond catalysis is mainly contribution of electrostatic interaction,while that of classical Lewis acid catalysis is mainly catalyzed by orbital interaction.The halogen bond donor catalysts(ICI_(3),IF_(3))are expected to be efficient catalysts for the reaction and further promote the chemical synthesis of carbonyl-olefin ring-closing metathesis reaction. 展开更多
关键词 Halogen bond donors Lewis acids Electrostatic interactions Orbital interaction Carbonyl-olefin ring-closing metathesis
原文传递
新型麦角新碱中间体的合成
4
作者 郭振波 彭玉洁 +2 位作者 权威 梁跃辉 王立升 《合成化学》 CAS 北大核心 2019年第1期31-34,68,共5页
以2-甲基-3-硝基苯胺为起始原料,经Batcho-Leimgruber、酰化、还原、氧化、R)-叔丁基亚磺酰胺的不对称诱导、烯烃闭环复分解反应等关键步骤,共经12步反应合成了麦角新碱中间体(S)-4-溴-3-{[5-(甲氧基羰基)-1-甲基-1,2,3,6-四氢吡啶-2-基... 以2-甲基-3-硝基苯胺为起始原料,经Batcho-Leimgruber、酰化、还原、氧化、R)-叔丁基亚磺酰胺的不对称诱导、烯烃闭环复分解反应等关键步骤,共经12步反应合成了麦角新碱中间体(S)-4-溴-3-{[5-(甲氧基羰基)-1-甲基-1,2,3,6-四氢吡啶-2-基]甲基}-1H-吲哚-1-甲酸叔丁酯,总收率7. 2%,该路线涉及4个新化合物的合成,其结构经~1H NMR,^(13)C NMR和MS(ESI)表征。 展开更多
关键词 2-甲基-3-硝基苯胺 麦角新碱 叔丁基亚磺酰胺 烯烃闭环复分解反应 合成
下载PDF
Syntheses of Macrocyclic Amides from L-Amino Acid Esters by RCM
5
作者 ZHAO Bao-xiang SCHAUDT Marco BLECHERT Siegfried 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2007年第1期22-30,共9页
A series of succinate-derived macrocyclic amides(1) was synthesized via ring-closing metathesis(RCM) as the key step. The substrate included 12 to 15 members. The metathesis precursors were obtained from the amide... A series of succinate-derived macrocyclic amides(1) was synthesized via ring-closing metathesis(RCM) as the key step. The substrate included 12 to 15 members. The metathesis precursors were obtained from the amide coupling of ten-butyl 3-carboxyhex-5-enoate(2) with numerous side-chain aikenylated amino acid esters of general type(3) derived from L-lysine and L-ornithine. 展开更多
关键词 ring-closing metathesis L-LYSINE L-ORNITHINE Allyl succinate MACROCYCLE
下载PDF
Efficient Total Synthesis of (S)-Dihydroresorcylide, a Bioactive Twelve-Membered Macrolide 被引量:1
6
作者 Li Zhang Wenquan Ma +2 位作者 Lili Xu Fei Deng Yuewei Guo 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2013年第3期339-343,共5页
The efficient synthesis of (S)-dihydroresorcylide (la) along with trans-resorcylide dimethyl ether (2b), was achieved in linear 9 steps from commercially available orcinol monohydrate (6) with esterification, ... The efficient synthesis of (S)-dihydroresorcylide (la) along with trans-resorcylide dimethyl ether (2b), was achieved in linear 9 steps from commercially available orcinol monohydrate (6) with esterification, carbonylation, and ring-closing metathesis (RCM) as the key steps in the synthetic sequence. 展开更多
关键词 dihydroresorcylide trans-resorcylide dimethyl ether ring-closing metathesis (RCM) carbonylation total synthesis
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部