Non-human primate species are considered as good models for human cancer research. Despite the relevant phylogenetic position of prosimians, few reports of neoplastic diseases have been described in these species. The...Non-human primate species are considered as good models for human cancer research. Despite the relevant phylogenetic position of prosimians, few reports of neoplastic diseases have been described in these species. The current study investigated implication of an intestinal T-cell lymphoma in a 5-year-old female ring-tailed lemur (Lemur catta) hosted at Parco Natura Viva, an Italian zoological garden. First, a sub-occlusive thickening of the small bowel was found. Histologically, the lesion was caused by a malignant lymphoid infiltrate that was homogeneously CD3+. Moreover, inflammatory patterns peripheral to the lesion suggested a coeliac disease similar to that reported in human. A huge malignant lymphoid infiltrate was present also in the liver and spleen. Overall, the case suggests an etiopathological relationship between coeliac-like disease and intestinal T-lymphoma, as reported in several human studies. Findings from this study are useful to improve our knowledge on the occurrence of the T-lymphoma as well as to improve the husbandry and dietary protocol of prosimians in zoos.展开更多
Objective:To observe morphology of Auchenacantha galeopteri(A.galeopteri),Auchenacantha spinosa(A.spinosa) and Auchenacantha parva(A.parva) from Sukabumi and Ujung Kulon, Indonesia using scanning electron microscopy(S...Objective:To observe morphology of Auchenacantha galeopteri(A.galeopteri),Auchenacantha spinosa(A.spinosa) and Auchenacantha parva(A.parva) from Sukabumi and Ujung Kulon, Indonesia using scanning electron microscopy(SEM).Methods:Specimens for light microscopy examination were fixed with warm 70%alcohol,cleared and mounted in lactophenol for wet mounting.Drawings were made with the aid of a drawing tube attached to a Nikon compound microscope.Specimens for SEM examination were processed according to Bozzola.Measurements were given in micrometers(μ m) as the average of findings,followed by the range in parentheses, unless otherwise stated.Results:The measurements of Auchenacantha spp are same with those of previously described.The striatums of male and female A.galeopteri are widen towards outside and wavy.The mouth of female with 6 lips,each of them is wider at base than distal end in A.galeopteri and rectangular in A.spinosa.Both species have dentiform protrusion from inner surface of lips,such structure absent in A.parva,but the lips with transverse festoon like pattern at anterior end of each lip.Conclusions:Using SEM,the lip and the striation pattern of three species of Auchenacantha can be clearly distinguished.Sukabumi and Ujung Kulon are new locality of A.galeopteri and A.spinosa,and A.parva is the new record in Indonesia.展开更多
文摘Non-human primate species are considered as good models for human cancer research. Despite the relevant phylogenetic position of prosimians, few reports of neoplastic diseases have been described in these species. The current study investigated implication of an intestinal T-cell lymphoma in a 5-year-old female ring-tailed lemur (Lemur catta) hosted at Parco Natura Viva, an Italian zoological garden. First, a sub-occlusive thickening of the small bowel was found. Histologically, the lesion was caused by a malignant lymphoid infiltrate that was homogeneously CD3+. Moreover, inflammatory patterns peripheral to the lesion suggested a coeliac disease similar to that reported in human. A huge malignant lymphoid infiltrate was present also in the liver and spleen. Overall, the case suggests an etiopathological relationship between coeliac-like disease and intestinal T-lymphoma, as reported in several human studies. Findings from this study are useful to improve our knowledge on the occurrence of the T-lymphoma as well as to improve the husbandry and dietary protocol of prosimians in zoos.
基金Supported by DIPA.Project/2010 of Research Centre on Biology-LIPI
文摘Objective:To observe morphology of Auchenacantha galeopteri(A.galeopteri),Auchenacantha spinosa(A.spinosa) and Auchenacantha parva(A.parva) from Sukabumi and Ujung Kulon, Indonesia using scanning electron microscopy(SEM).Methods:Specimens for light microscopy examination were fixed with warm 70%alcohol,cleared and mounted in lactophenol for wet mounting.Drawings were made with the aid of a drawing tube attached to a Nikon compound microscope.Specimens for SEM examination were processed according to Bozzola.Measurements were given in micrometers(μ m) as the average of findings,followed by the range in parentheses, unless otherwise stated.Results:The measurements of Auchenacantha spp are same with those of previously described.The striatums of male and female A.galeopteri are widen towards outside and wavy.The mouth of female with 6 lips,each of them is wider at base than distal end in A.galeopteri and rectangular in A.spinosa.Both species have dentiform protrusion from inner surface of lips,such structure absent in A.parva,but the lips with transverse festoon like pattern at anterior end of each lip.Conclusions:Using SEM,the lip and the striation pattern of three species of Auchenacantha can be clearly distinguished.Sukabumi and Ujung Kulon are new locality of A.galeopteri and A.spinosa,and A.parva is the new record in Indonesia.
