Trends and hotspots in gastrointestinal neoplasms risk assessment: A bibliometric analysis from 1984 to 2022

BACKGROUND Gastrointestinal neoplasm(GN)significantly impact the global cancer burden and mortality,necessitating early detection and treatment.Understanding the evolution and current state of research in this field is vital.AIM To conducts a comprehensive bibliometric analysis of publications from 1984 to 2022 to elucidate the trends and hotspots in the GN risk assessment research,focusing on key contributors,institutions,and thematic evolution.METHODS This study conducted a bibliometric analysis of data from the Web of Science Core Collection database using the"bibliometrix"R package,VOSviewer,and CiteSpace.The analysis focused on the distribution of publications,contributions by institutions and countries,and trends in keywords.The methods included data synthesis,network analysis,and visualization of international collaboration networks.RESULTS This analysis of 1371 articles on GN risk assessment revealed a notable evolution in terms of research focus and collaboration.It highlights the United States'critical role in advancing this field,with significant contributions from institutions such as Brigham and Women's Hospital and the National Cancer Institute.The last five years,substantial advancements have been made,representing nearly 45%of the examined literature.Publication rates have dramatically increased,from 20 articles in 2002 to 112 in 2022,reflecting intensified research efforts.This study underscores a growing trend toward interdisciplinary and international collaboration,with the Journal of Clinical Oncology standing out as a key publication outlet.This shift toward more comprehensive and collaborative research methods marks a significant step in addressing GN risks.CONCLUSION This study underscores advancements in GN risk assessment through genetic analyses and machine learning and reveals significant geographical disparities in research emphasis.This calls for enhanced global collaboration and integration of artificial intelligence to improve cancer prevention and treatment accuracy,ultimately enhancing worldwide patient care.

Investigation and Risk Assessment of Alien Invasive Plants in Riparian Zone of Dongjiang River

[Objective] The aim was to conduct investigation and risk assessment of the alien invasive plants in riparian zone of Dongjiang River.[Method] The field survey was carried out by the combination methods of sampling plots investigation and route survey,and the whole Dongjiang River was covered.52 sampling points were set in the main streams,and 87 sampling points in tributaries streams,624 quadrats were set in total;multi-index comprehensive evaluation method was adopted for the risk assessment with 6 first-level indexes and 25 second-level indexes.[Result] Through the investigation on the riparian zone of Dongjiang River for 2 years,51 species of alien invasive plants were found,belonging to 17 families and 38 genera.The risk level assessment results of these 51 species showed that 18 species,such as Ageratum conyzoides,belonged to high-level risk with over 60 points;26 species,such as Chenopodium ambrosioides,were between 30 and 60 points which belonged to middle-level risk;7 species,such as Paspalum dilatatum,with less than 30 points belonged to low-level risk.[Conclusion] Basic data on the protection,water environmental management and functional zoning of riparian zone of Dongjiang River were provided.

Distribution, Mobility, and Health Risks Assessment of Trace Metals in River Sediments from Intense Agricultural Activity Areas in West Africa

The economy of West African countries is mainly based on agriculture. However, the trace metal(loid)s contamination status in rivers is relatively unknown in the region. In this work, 45 surface sediments collected from the Bandama, Comoé, and Bia Rivers in south and south eastern Côte d’Ivoire (West Africa), were analyzed for total metal concentrations and chemical speciation. The results showed that the river sediments were considerably contaminated by Cd and moderately contaminated by As, Cu, Pb, and Zn. Significant spatial variations were observed among the stations but not between the rivers. Metals Cd and Cu were likely to cause more ecological risks. The speciation analysis unravelled that the metal(loid)s partitioned mainly in the residual fraction, with the potential mobile fraction varying from 14% to 28%. The study calls for establishment of strict policies relative to the application of fertilizers and agrochemicals and mining activities to protect the environment and human health risks.

Penetration Study of Key Technologies for Cybersecurity Risk Assessment

In recent years,with the frequent occurrence of cyber security incidents,people have paid more attention to it.Information security risk assessment is a very important research topic.This paper gives a brief overview of the theory of cybersecurity risk assessment,focuses on the description of the current mainstream cybersecurity risk assessment methods,classifies and compares the existing methods according to the nature of the methods,and analyses the advantages,disadvantages,and application scope of each method.Finally,the main factors affecting the evaluation results are summarized and refined,and future research hotspots in this field are proposed.Through the empirical analysis of the three factors,the influence of the correlation of the three factors,the uncertainty of the evaluation indexes,and the timeliness of the evaluation on the evaluation results are concluded,which provides a reference for future research on evaluation methods.

FAULT TREE ANALYSIS OF SPONTANEOUS COMBUSTION OF SULPHIDE ORES AND ITS RISK ASSESSMENT

A logic fault tree of mine spontaneous combustion of sulphide ores was built by the fault tree analysis (FTA) based on a lot of mechanism investigation of sulphide ore spontaneous combustion in more than ten mines and review of a great amount of relevant

A risk assessment system for alien plant bio-invasion in Xiamen,China

Bio-invasion has caused serious ecosystem damage and enormous economic losses in China,and it has been the greatest factor to island bio-diversity reduction.Xiamen,as an important seaport with a relatively high conservation value,is particularly vulnerable to bio-invasion for its typical island ecosystem as well as frequent human-made disturbance.As a result of field surveys,literature review, and consultation with experts,a list of 67 alien plants identified as major invaders(12 species)and emerging invade...

Preoperative risk factor analysis in orthotopic liver transplantation with pretransplant artificial liver support therapy

AIM： To assess the value of pre-transplant artificial liver support in reducing the pre-operative risk factors relating to early mortality after orthotopic liver transplantation （OLT）. METHODS： Fifty adult patients with various stages and various etiologies undergoing OLT procedures were treated with molecular adsorbent recycling system （MARS） as preoperative liver support therapy. The study included two parts, the first one is to evaluate the medical effectiveness of single MARS treatment with some clinical and laboratory parameters, which were supposed to be the therapeutical pre-transplant risk factors, the second part is to study the patients undergoing OLT using the regression analysis on preoperative risk factors relating to early mortality （30 d） after OLT. RESULTS： In the 50 patients, the statistically significant improvement in the biochemical parameters was observed （pre-treatment and post-treatment）. Eight patients avoided the scheduled Ltx due to significant relief of clinical condition or recovery of failing liver function, 8 patients died, 34 patients were successfully bridged to Ltx, the immediate outcome of this 34 patients within 30d observation was： 28 kept alive and 6 patients died. CONCLUSION： Pre-operative SOFA, level of creatinine, INR, TNF-α, IL-10 are the main preoperative risk factors that cause early death after operation, MARS treatment before transplantion can relieve these factors significantly.

The Benefit Risk Assessment of Consumption of Marine Species Based on Benefit-Risk Analysis for Foods(BRAFO)-tiered Approach

Objective To assess the net health effect caused by the consumption of specific marine species based on Benefit-Risk Analysis for Foods （BRAFO）-tiered approach. Methods Twenty species were collected from the Zhoushan Archipelago, China. Concentrations of n-3 long-chain polyunsaturated fatty acids, methyl mercury （MeHg）, and dioxin-like compounds （DLCs） in the samples were analyzed for benefit risk assessment based on BRAFO-tiered approach. Results Based on the BRAFO-tiered approach, reference scenario （no intake） and alternative scenario （intake of specific species of 200 g/week） were determined. The exposure to MeHg/DLCs via alternative scenario of all studied species did not exceed provisional tolerable weekly/monthly intake. However, the adult population with high DLCs exposure in China would significantly exceed the upper limit of DLCs via an additional alternative scenario of some species such as Auxis thazard. The results of deterministic computation showed that alternative scenario of all studied species generated clear net beneficial effects on death prevention and child IQ gain. Conclusion The alternative scenario of all studied species could be recommended to population with average DLCs exposure, and the reference scenario of species with relatively high DLCs concentration could be recommended to population exposed to high DLCs.

The Pollution Character Analysis and Risk Assessment for Metals in Dust and PM_(10) around Road from China

INTRODUCTION In recent years, with the gradual improvement of road construction, the rapid increase of the number of motor vehicles, vehicle emissions and the current poor vehicle performance, poor vehicle maintenance, higher emission factor and so on, air pollution caused by the traffic issues becomes the focus of people attention. The harmful substances are gradually accumulated to atmosphere particles surrounding roads due to dust particles （soil dusts, road dusts, construction dusts）, coal emissions, industrial emissions, vehicle emissions, biomass burning, secondary particles, which has a certain harmful influence to the atmosphere, soil and plants surrounding roads.

Comparison of Risk Assessment for a Nuclear Power Plant Construction Project Based on Analytic Hierarchy Process and Fuzzy Analytic Hierarchy Process

Recently, plant construction throughout the world, including nuclear power plant construction, has grown significantly. The scale of Korea’s nuclear power plant construction in particular, has increased gradually since it won a contract for a nuclear power plant construction project in the United Arab Emirates in 2009. However, time and monetary resources have been lost in some nuclear power plant construction sites due to lack of risk management ability. The need to prevent losses at nuclear power plant construction sites has become more urgent because it demands professional skills and large-scale resources. Therefore, in this study, the Analytic Hierarchy Process (AHP) and Fuzzy Analytic Hierarchy Process (FAHP) were applied in order to make comparisons between decision-making methods, to assess the potential risks at nuclear power plant construction sites. To suggest the appropriate choice between two decision-making methods, a survey was carried out. From the results, the importance and the priority of 24 risk factors, classified by process, cost, safety, and quality, were analyzed. The FAHP was identified as a suitable method for risk assessment of nuclear power plant construction, compared with risk assessment using the AHP. These risk factors will be able to serve as baseline data for risk management in nuclear power plant construction projects.

Non-parametric Statistical Analysis and Spatial Distribution of the Regional Geochemical Data of the Okiep Copper District,Namaqualand,South Africa:Implications for Anthropogenic Influence and Risk Assessment

The Okiep Copper District is the oldest mining district in South Africa with a legacy of more than 150 years of mining.This legacy can be felt in the presence of large tailings dams scattered throughout the area.These tailings have a deleterious impact on the surrounding environment.To use geochemical methods in determining the scale of the impact, pre-mining background levels need to be determined. This is especially difficult in areas for which

Invasion Risk Assessment of Exotic Plant Praxelis clematidea in Zhengzhou

To reduce the harms of plant invasion,the risk assessment for biological invasion of exotic species（ including intentionally introduced species and accidentally introduced species） is particularly important. Through data review,investigation research and expert consultation,risk assessment system and standard for exotic species invasion in Zhengzhou region was established. Risk of Praxelis clematidea was assessed,in order to provide a reference for possible biological invasion of exotic plants in Zhengzhou.

Levels of Genotoxic and Carcinogenic Ingredients in Plant Food Supplements and Associated Risk Assessment

The present study describes the selection, analysis and risk assessment of genotoxic and carcinogenic ingredients of botanicals and botanical preparations which can be found in food and plant food supplements (PFS). First an inventory was made of botanical ingredients that are of possible concern for human health because of their genotoxic and/or carcinogenic properties. In total, 30 botanical ingredients were selected and subsequently judged for their actual genotoxic and/or carcinogenic potential. Among the 30 compounds considered, 18 compounds were judged to be both genotoxic and carcinogenic. Interestingly, the majority of these compounds belong to the group of alkenylbenzenes or unsaturated pyrrolizidine alkaloids. Subsequently, based on available carcinogenicity data and estimated daily human exposure that was determined focusing on the intake from PFS, the Margin of Exposure (MOE) was calculated for the alkenylbenzenes estragole, methyleugenol, safrole and β-asarone. Calculating the MOEs for intake estimates of these alkenylbenzenes from PFS resulted in MOE values that were generally lower than 10,000 and often lower than 100. In some cases the MOE was even below 10 meaning that the estimated daily intake is in the range of dose levels causing malignant tumors in experimental animals. This result indicates that the use of PFS containing the genotoxic carcinogens estragole, methyleugenol, safrole or β-asarone might raise a potential concern for human health and would be of high priority for risk management.

Risk Assessment,Management and Application in Nuclear Power Plant Operation

To introduce the basic concepts of technical specification of nuclear power plant,a risk assessment and management technique based on the probabilistic safety analysis( PSA) method was proposed. The risk-informed method was used,and an example was given to show how to use some specific risk metrics like CDF / LERF /ICDP / ILERP to analyze and manage the risk associated with activities in nuclear power plant operation. The advantage of this technique can be concluded from this paper,and this technique should be used more widely and deeply in nuclear industry.

Introduction of New Method on Engineering Risk Assessment:Engineering Errors and Effects Analysis(3EA)

Construction and commissioning accidents investigation shows that engineer’s errors in basic and detailed phases are the main causes.It will be gained more efficiency of investment when a relevant method is applied for error identification and risk assessment in basic and detailed phases.Most of risk assessment methods are related to construction phase,meanwhile hidden risks that were happen in previous phases cannot be found by these methods.Although HAZOP study can be applied in detail phase but it can help to find process defections.Importance of identifying risks in basic and detailed phases is to apply preventive actions against birth and grows risks.This risk assessment method can reduce costs and improve environmental protection,safety,and reliability of designs.The main purpose of this study is to identify engineer’s errors and analyse their HSE effects.The method is applied in seven oil and gas engineering projects in Iran,raising the level of engineer’s attention to safety precautions and environmentally-friendly design,reducing the cost of improving the level of safety and environmental protection,improving environmental protection,safety,and design reliability,and improving procedures related to design process and control have been achieved.

The Analysis and Assessment of the Creation Investment Risk in the High and New Technology, Enterprise

The creation risk investmentof the high and new technology enterprise isthe way to finance：and invest for the business period. After we putting the capital into the high and new. technology project.that is in the devetopment stage, the enterprise can, acquire high, increase, by the. support and assistance ＇of, the. capital and management. After the enterprise grew up, it can achieve high benefits by selling stock, attorning the enterprise, and dealing property rights, etc. Finally it secedes form the enterprise invested. The purpose of total analysis in the respective stage for the business investment cause including cause prosperities, object, risk, is to comprehensively understand the effect on the anticipation ratio of the benefit, investment distribution, the stock property proportion which is offered by the activity content, and the emphasis of the assessment in the respective stages of the creation risk investment cause.

Maritime Oil Spill Risk Assessment for Hanhikivi Nuclear Power Plant

Fennovoima is planning to build a new nuclear power plant unit-Hanhikivi 1, on a greenfield site in Northern Finland. A nearby maritime oil spill accident is one of the external events analysed in the probabilistic risk assessment of the plant. In the worst case, the oil could cause a loss of the ultimate heat sink by blocking the sea water intake screens. By considering the maritime traffic, oil transport and oil spill accident data in the Baltic Sea area, the annual probabilities of nearby, significant oil spills are evaluated. Event tree analysis is used to evaluate the probability that significant amount of oil enters the plant intake tunnel. The spill behaviour is considered, including oil spreading, dissolution, dispersion and movement due to wind and currents. In addition, oil combat measures including the use ofoil booms and skimmers are evaluated.

Multi-mycotoxin exposure and risk assessments for Chinese consumption of nuts and dried fruits

In this study, 15 mycotoxins were detected in 233 nut and dried fruit samples from China. The 15 mycotoxins included aflatoxins （AFs： AFB1, AFB2, AFG1 and AFG2）, trichothecene toxins （TCs： T-2, ZEA, ENA, ENA1, ENB, ENB1 and BEA）, Alternaria toxins （ATs： TEN, AOH and AME） and ochratoxin A （OTA）. The mycotoxins were detected in 47.6% of the samples and all 15 of the mycotoxins were found. Two samples were positive for AFB1 and exceeded the maximum tolerable levels allowed in China. The contamination levels of the mycotoxins found in nuts, dried jujubes, raisins, dried figs and dried Iongans were in the ranges of 0.1-462.7, 0.2-247.3, 0.8-10.1,0.2-384.1 and 0.1-89.2 μg kg^-1, respectively. Dried figs （80.0%） had the highest incidence of mycotoxins, followed by dried Iongans （60.0%）, dried jujubes （57.1%）, nuts （43.6%） and raisins （26.7%）. The estimated daily intake （EDI） values of each individual mycotoxin and all of the mycotoxins collectively were calculated by both the deterministic approach （DA） and the probability approach （PA）. For risk characterization, dietary exposure to TCs, ATs and OTA through consumption of nuts and dried fruits according to both approaches, showed no health risk to Chinese adults by exposure to either individual mycotoxins or in combination. To the best of our knowledge, this is the first work in which risk assessment of multimycotoxins is performed, specifically including the emerging ENNs and BEA, in nuts and dried fruits of China.

Comparing rockfall hazard and risk assessment procedures along roads for different planning purposes

Hazard and risk assessment procedures of different types of rockfall were analyzed to compare their outcomes when they are applied to the same case study.Although numerous methodologies are available in literature,rockfall hazard and risk analyses are often limited to standard estimations,affected by a margin of uncertainty,especially when relevant engineering projects are about to be realized.Based on the design purpose,different types of approaches can be chosen among the qualitative and quantitative ones available in literature,which allow different levels of analysis.One of the main criticisms related to rockfall events is the risk affecting linear structures,such as road or railways,due both to their strategic relevance for trade and communications and to the great entity of the exposed value(traffic units)traveling along them.In this perspective,a comparison between the qualitative method known as Evolving Rockfall Hazard Assessment(EHRA),the semi-quantitative modified Rockfall Hazard Rating System(RHRS)and the quantitative Rockfall Risk Management(RoMa)approach is herein commented according to a practical application to a case study.It is the case of the rockfall threat along slopes crossed by a strategic road connecting two of the most known spots of eastern Sicily(Italy),at the Taormina tourist complex.Data were retrieved from both recent literature and technical surveys on field.Achieved results highlight how the approaches are affected by a different level of detail and uncertainty,arising also by some necessary assumption that must be taken into account,especially when mitigation measures or territory planning have to be designed.Achieved results can be also taken into account for similar studies worldwide,in order to choose the most suitable procedure based on the design purpose.This is indeed crucial in the perspective of the optimization of time and economic resources in the territorial planning practice.

Landslide Hazard and Risk Assessment on the Northern Slope of Mt. Changbai, China

Landslide hazard and risk assessment on the northern slope of Mt. Changbai, a well-known tourist attraction near the North Korean-Chinese border, are assessed. This study is divided into two parts, namely, landslide hazard zonation and risk assessment. The 1992 Anbalagan and Singh method of landslide hazard zonation （LHZ） was modified and used in this area. In this way, an Associative Analysis Method was used in representative areas to get a measure for controlling factors （slope gradient, relative relief, vegetation, geology, discontinuity development, weak layer thickness and ground water）. For the membership degree of factor to slope failure, the middle range of limited values was used to calculate LHZ. Based on an estimation of the potential damage from slope failure, a reasonable risk assessment map was obtained using the relationship of potential damage and probable hazard to aid future planning and prediction and to avert loss of life.