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Tailoring Classical Conditioning Behavior in TiO_(2) Nanowires:ZnO QDs-Based Optoelectronic Memristors for Neuromorphic Hardware
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作者 Wenxiao Wang Yaqi Wang +5 位作者 Feifei Yin Hongsen Niu Young-Kee Shin Yang Li Eun-Seong Kim Nam-Young Kim 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第7期265-280,共16页
Neuromorphic hardware equipped with associative learn-ing capabilities presents fascinating applications in the next generation of artificial intelligence.However,research into synaptic devices exhibiting complex asso... Neuromorphic hardware equipped with associative learn-ing capabilities presents fascinating applications in the next generation of artificial intelligence.However,research into synaptic devices exhibiting complex associative learning behaviors is still nascent.Here,an optoelec-tronic memristor based on Ag/TiO_(2) Nanowires:ZnO Quantum dots/FTO was proposed and constructed to emulate the biological associative learning behaviors.Effective implementation of synaptic behaviors,including long and short-term plasticity,and learning-forgetting-relearning behaviors,were achieved in the device through the application of light and electrical stimuli.Leveraging the optoelectronic co-modulated characteristics,a simulation of neuromorphic computing was conducted,resulting in a handwriting digit recognition accuracy of 88.9%.Furthermore,a 3×7 memristor array was constructed,confirming its application in artificial visual memory.Most importantly,complex biological associative learning behaviors were emulated by mapping the light and electrical stimuli into conditioned and unconditioned stimuli,respectively.After training through associative pairs,reflexes could be triggered solely using light stimuli.Comprehen-sively,under specific optoelectronic signal applications,the four features of classical conditioning,namely acquisition,extinction,recovery,and generalization,were elegantly emulated.This work provides an optoelectronic memristor with associative behavior capabilities,offering a pathway for advancing brain-machine interfaces,autonomous robots,and machine self-learning in the future. 展开更多
关键词 Artificial intelligence Classical conditioning Neuromorphic computing Artificial visual memory Optoelectronic memristors ZnO Quantum dots
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Uncertainties of landslide susceptibility prediction: Influences of random errors in landslide conditioning factors and errors reduction by low pass filter method
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作者 Faming Huang Zuokui Teng +4 位作者 Chi Yao Shui-Hua Jiang Filippo Catani Wei Chen Jinsong Huang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期213-230,共18页
In the existing landslide susceptibility prediction(LSP)models,the influences of random errors in landslide conditioning factors on LSP are not considered,instead the original conditioning factors are directly taken a... In the existing landslide susceptibility prediction(LSP)models,the influences of random errors in landslide conditioning factors on LSP are not considered,instead the original conditioning factors are directly taken as the model inputs,which brings uncertainties to LSP results.This study aims to reveal the influence rules of the different proportional random errors in conditioning factors on the LSP un-certainties,and further explore a method which can effectively reduce the random errors in conditioning factors.The original conditioning factors are firstly used to construct original factors-based LSP models,and then different random errors of 5%,10%,15% and 20%are added to these original factors for con-structing relevant errors-based LSP models.Secondly,low-pass filter-based LSP models are constructed by eliminating the random errors using low-pass filter method.Thirdly,the Ruijin County of China with 370 landslides and 16 conditioning factors are used as study case.Three typical machine learning models,i.e.multilayer perceptron(MLP),support vector machine(SVM)and random forest(RF),are selected as LSP models.Finally,the LSP uncertainties are discussed and results show that:(1)The low-pass filter can effectively reduce the random errors in conditioning factors to decrease the LSP uncertainties.(2)With the proportions of random errors increasing from 5%to 20%,the LSP uncertainty increases continuously.(3)The original factors-based models are feasible for LSP in the absence of more accurate conditioning factors.(4)The influence degrees of two uncertainty issues,machine learning models and different proportions of random errors,on the LSP modeling are large and basically the same.(5)The Shapley values effectively explain the internal mechanism of machine learning model predicting landslide sus-ceptibility.In conclusion,greater proportion of random errors in conditioning factors results in higher LSP uncertainty,and low-pass filter can effectively reduce these random errors. 展开更多
关键词 Landslide susceptibility prediction conditioning factor errors Low-pass filter method Machine learning models Interpretability analysis
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Autologous hematopoietic stem cell transplantation conditioning regimens and chimeric antigen receptor T cell therapy in various diseases
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作者 Shahzaib Maqbool Maryam Farhan Baloch +2 位作者 Muhammad Abdul Khaliq Khan Azeem Khalid Kiran Naimat 《World Journal of Transplantation》 2024年第1期32-41,共10页
Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,nega... Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,negative consequences have also been recorded.Multiple conditioning regimens were extracted from various literature searches from databases like PubMed,Google scholar,EMBASE,and Cochrane.Conditioning regimens for each disease were compared by using various end points such as overall survival(OS),progression free survival(PFS),and leukemia free survival(LFS).Variables were presented on graphs and analyzed to conclude a more efficacious conditioning regimen.In multiple myeloma,the most effective regimen was high dose melphalan(MEL)given at a dose of 200/mg/m2.The comparative results of acute myeloid leukemia were presented and the regimens that proved to be at an admirable position were busulfan(BU)+MEL regarding OS and BU+VP16 regarding LFS.In case of acute lymphoblastic leukemia(ALL),BU,fludarabine,and etoposide(BuFluVP)conferred good disease control not only with a paramount improvement in survival rate but also low risk of recurrence.However,for ALL,chimeric antigen receptor(CAR)T cell therapy was preferred in the context of better OS and LFS.With respect to Hodgkin’s lymphoma,mitoxantrone(MITO)/MEL overtook carmustine,VP16,cytarabine,and MEL in view of PFS and vice versa regarding OS.Non-Hodgkin’s lymphoma patients were administered MITO(60 mg/m2)and MEL(180 mg/m2)which showed promising results.Lastly,amyloidosis was considered,and the regimen that proved to be competent was MEL 200(200 mg/m2).This review article demonstrates a comparison between various conditioning regimens employed in different diseases. 展开更多
关键词 conditioning regimens Multiple myeloma LYMPHOMA HODGKIN NON-HODGKIN Acute leukemia
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The potential mechanism and clinical application value of remote ischemic conditioning in stroke
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作者 Yajun Zhu Xiaoguo Li +6 位作者 Xingwei Lei Liuyang Tang Daochen Wen Bo Zeng Xiaofeng Zhang Zichao Huang Zongduo Guo 《Neural Regeneration Research》 SCIE CAS 2025年第6期1613-1627,共15页
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may... Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation, cellular immunity, apoptosis, and autophagy, the exact underlying molecular mechanisms are unclear. This review summarizes the current status of different types of remote ischemic conditioning methods in animal and clinical studies and analyzes their commonalities and differences in neuroprotective mechanisms and signaling pathways. Remote ischemic conditioning has emerged as a potential therapeutic approach for improving stroke-induced brain injury owing to its simplicity, non-invasiveness, safety, and patient tolerability. Different forms of remote ischemic conditioning exhibit distinct intervention patterns, timing, and application range. Mechanistically, remote ischemic conditioning can exert neuroprotective effects by activating the Notch1/phosphatidylinositol 3-kinase/Akt signaling pathway, improving cerebral perfusion, suppressing neuroinflammation, inhibiting cell apoptosis, activating autophagy, and promoting neural regeneration. While remote ischemic conditioning has shown potential in improving stroke outcomes, its full clinical translation has not yet been achieved. 展开更多
关键词 Akt apoptosis autophagy cerebral perfusion cerebral vascular stenosis clinical transformation hemorrhagic stroke ischemic stroke NEUROINFLAMMATION neuroprotection Notch1 PI3K remote ischemic conditioning STROKE
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Operating Parameters of the District Heating Substation Cooperating With the Installation of Technological Air Conditioning With High Efficiency of Heat Recovery
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作者 Żarski Kazimierz Kryża Mariusz 《Chinese Business Review》 2024年第1期1-12,共12页
The article analyses the problem of determining the operating parameters of the district heating substation cooperating with the air heating system in technological air conditioning systems equipped with heat exchange... The article analyses the problem of determining the operating parameters of the district heating substation cooperating with the air heating system in technological air conditioning systems equipped with heat exchangers with high efficiency of heat recovery.Attention was paid to the correct selection of heat exchangers for the heat output balance depending on the heat recovery protection algorithms against a drop in the temperature of the heat transfer surface below 0℃.Critical parameters were determined in Polish climatic conditions,at which the operation of the heat recovery exchanger in the air conditioning system is switched off or limited.It has been proven that the proper functioning of the district heating substation cooperating with the installation of air conditioning with high heat recovery efficiency requires the use of two heat exchangers with different characteristics,equipped with properly selected temperature control systems.The optimal model of cooperation between the technological air conditioning system and the heating substation was also indicated. 展开更多
关键词 ventilation of operating theatre air conditioning flow control in heating circuit
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Landslide susceptibility prediction using slope unit-based machine learning models considering the heterogeneity of conditioning factors 被引量:3
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作者 Zhilu Chang Filippo Catani +4 位作者 Faming Huang Gengzhe Liu Sansar Raj Meena Jinsong Huang Chuangbing Zhou 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第5期1127-1143,共17页
To perform landslide susceptibility prediction(LSP),it is important to select appropriate mapping unit and landslide-related conditioning factors.The efficient and automatic multi-scale segmentation(MSS)method propose... To perform landslide susceptibility prediction(LSP),it is important to select appropriate mapping unit and landslide-related conditioning factors.The efficient and automatic multi-scale segmentation(MSS)method proposed by the authors promotes the application of slope units.However,LSP modeling based on these slope units has not been performed.Moreover,the heterogeneity of conditioning factors in slope units is neglected,leading to incomplete input variables of LSP modeling.In this study,the slope units extracted by the MSS method are used to construct LSP modeling,and the heterogeneity of conditioning factors is represented by the internal variations of conditioning factors within slope unit using the descriptive statistics features of mean,standard deviation and range.Thus,slope units-based machine learning models considering internal variations of conditioning factors(variant slope-machine learning)are proposed.The Chongyi County is selected as the case study and is divided into 53,055 slope units.Fifteen original slope unit-based conditioning factors are expanded to 38 slope unit-based conditioning factors through considering their internal variations.Random forest(RF)and multi-layer perceptron(MLP)machine learning models are used to construct variant Slope-RF and Slope-MLP models.Meanwhile,the Slope-RF and Slope-MLP models without considering the internal variations of conditioning factors,and conventional grid units-based machine learning(Grid-RF and MLP)models are built for comparisons through the LSP performance assessments.Results show that the variant Slopemachine learning models have higher LSP performances than Slope-machine learning models;LSP results of variant Slope-machine learning models have stronger directivity and practical application than Grid-machine learning models.It is concluded that slope units extracted by MSS method can be appropriate for LSP modeling,and the heterogeneity of conditioning factors within slope units can more comprehensively reflect the relationships between conditioning factors and landslides.The research results have important reference significance for land use and landslide prevention. 展开更多
关键词 Landslide susceptibility prediction(LSP) Slope unit Multi-scale segmentation method(MSS) Heterogeneity of conditioning factors Machine learning models
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Recent Advances in Pure-Organic Host-Guest Room-Temperature Phosphorescence Systems Toward Bioimaging
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作者 Zhiqin Wu Yang Li Xiang Ma 《Transactions of Tianjin University》 EI CAS 2023年第6期432-443,共12页
Organic room-temperature phosphorescence(RTP)materials have garnered considerable attention in the fields of biosensing,optoelectronic devices,and anticounterfeiting because of their substantial Stokes shifts,tunable ... Organic room-temperature phosphorescence(RTP)materials have garnered considerable attention in the fields of biosensing,optoelectronic devices,and anticounterfeiting because of their substantial Stokes shifts,tunable emission wavelengths,and prolonged lifetimes.These materials offer remarkable advantages for biological imaging applications by effectively reducing environmental autofluorescence and enhancing imaging resolution.Recently,host-guest systems have been employed as efficient approaches to fabricate pure-organic RTP materials for bioimaging,providing benefits such as controllable preparation and flexible modulation.Consequently,an increasing number of corresponding studies are being reported;however,a comprehensive systematic review is still lacking.Therefore,we summarize recent advances in the development of pureorganic RTP materials using host-guest systems with regard to bioimaging,including rigid matrices and sensitization.The challenge and potential of RTP for biological imaging are also proposed to promote the biomedical applications of organic RTP materials with excellent optical properties. 展开更多
关键词 room-temperature phosphorescence Host-guest system Rigid matrix Biological imaging
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Room-Temperature Phosphorescence and Lifetime of Fossil Resins (Amber) from Dominican Republic, Mexico, Baltic Sea, Myanmar, and Fushun, China
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作者 Zhiqing Zhang Yamei Wang Andy H.Shen 《宝石和宝石学杂志(中英文)》 CAS 2023年第4期111-119,共9页
Amber can emit room temperature phosphorescence(RTP)under the well-known 365 nm fluorescence ultraviolet light.This paper is devoted to the phosphorescence study of 20 pieces of amber materials from the Dominican Repu... Amber can emit room temperature phosphorescence(RTP)under the well-known 365 nm fluorescence ultraviolet light.This paper is devoted to the phosphorescence study of 20 pieces of amber materials from the Dominican Republic,Mexico,Baltic sea,Myanmar,and Fushun,China.The results show that amber from the same geographic origin has similar shape in phosphorescence spectra.However,the shape of the amber phosphorescence spectra varies depending on their different localities.Burmite(amber from Myanmar)and Fushun amber have a bright yellow phosphorescence with a long lifetime,while the Dominican and Mexican ones are weaker and last shorter.The irradiation of Baltic amber becomes faint or even inert.Phosphorescence spectral Gaussian fitting results suggest an emission maximum near 550 nm in most amber samples.Their phosphorescence lifetime,analyzed through the exponential function fitting,is up to 1 second in Burmite and Fushun samples,shorter in the Dominican and Mexican ones,about 0.230 s,and the shortest in Baltic amber,close to 0.151 s.These variations of phosphorescence lifetime and intensity are related to the relative geological ages of these amber.It indicated that the phosphorescence agent was probably formed during the long geological time.While the anomaly occurred in Baltic amber,the only one found in a sea secondary deposit form,it demonstrated that the terrestrial geological environment these amber preserved has prevented the phosphorescence agent to be deactivated. 展开更多
关键词 ossil resin AMBER room-temperature phosphorescence(RTP) phosphorescence lifetime
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Localized Theoretical Analysis of Thermal Performance of Individually Finned Heat Pipe Heat Exchanger for Air Conditioning with Freon R404A as Working Fluid
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作者 Élcio Nogueira 《Journal of Materials Science and Chemical Engineering》 2023年第8期61-85,共17页
This work contributes to the improvement of energy-saving in air conditioning systems. The objective is to apply the thermal efficiency of heat exchangers for localized determination of the thermal performance of heat... This work contributes to the improvement of energy-saving in air conditioning systems. The objective is to apply the thermal efficiency of heat exchangers for localized determination of the thermal performance of heat exchangers with individually finned heat pipes. The fundamental parameters used for performance analysis were the number of fins per heat pipe, the number of heat pipes, the inlet temperatures, and the flow rates of hot and cold fluids. The heat exchanger under analysis uses Freon 404A as a working fluid in an air conditioning system for cooling in the Evaporator and energy recovery in the Condenser. The theoretical model is localized and applied individually to the Evaporator, Condenser, and heat exchanger regions. The results obtained through the simulation are compared with experimental results that use a global approach for the heat exchanger. The thermal quantities obtained through the theoretical model in the mentioned regions are air velocity, Nusselt number, thermal effectiveness, heat transfer rate, and outlet temperature. The comparisons made with global experimental results are in excellent agreement, demonstrating that the localized theoretical approach developed is consistent and can be used as a comprehensive analysis tool for heat exchangers using heat pipes. 展开更多
关键词 Individually Finned Heat Pipe Heat Exchanger Thermal Efficiency Thermal Effectiveness Air conditioning Freon R404A
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Localized Theoretical Analysis of Thermal Performance of Individually Finned Heat Pipe Heat Exchanger for Air Conditioning with Freon R404A as Working Fluid
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作者 Élcio Nogueira 《Journal of Modern Physics》 2023年第8期61-85,共6页
This work contributes to the improvement of energy-saving in air conditioning systems. The objective is to apply the thermal efficiency of heat exchangers for localized determination of the thermal performance of heat... This work contributes to the improvement of energy-saving in air conditioning systems. The objective is to apply the thermal efficiency of heat exchangers for localized determination of the thermal performance of heat exchangers with individually finned heat pipes. The fundamental parameters used for performance analysis were the number of fins per heat pipe, the number of heat pipes, the inlet temperatures, and the flow rates of hot and cold fluids. The heat exchanger under analysis uses Freon 404A as a working fluid in an air conditioning system for cooling in the Evaporator and energy recovery in the Condenser. The theoretical model is localized and applied individually to the Evaporator, Condenser, and heat exchanger regions. The results obtained through the simulation are compared with experimental results that use a global approach for the heat exchanger. The thermal quantities obtained through the theoretical model in the mentioned regions are air velocity, Nusselt number, thermal effectiveness, heat transfer rate, and outlet temperature. The comparisons made with global experimental results are in excellent agreement, demonstrating that the localized theoretical approach developed is consistent and can be used as a comprehensive analysis tool for heat exchangers using heat pipes. 展开更多
关键词 Individually Finned Heat Pipe Heat Exchanger Thermal Efficiency Thermal Effectiveness Air conditioning Freon R404A
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Oscillation properties of eigenfunctions for Sturm-Liouville problems with interface conditions via Prufer transformation
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作者 LI Zhi-yu LI Kun +2 位作者 CAI Jin-ming QIN Jian-fang ZHENG Zhao-wen 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第2期191-200,共10页
A class of Sturm-Liouville problems with discontinuity is studied in this paper.The oscillation properties of eigenfunctions for Sturm-Liouville problems with interface conditions are obtained.The main method used in ... A class of Sturm-Liouville problems with discontinuity is studied in this paper.The oscillation properties of eigenfunctions for Sturm-Liouville problems with interface conditions are obtained.The main method used in this paper is based on Prufer transformation,which is different from the classical ones.Moreover,we give two examples to verify our main results. 展开更多
关键词 Sturm-Liouville problem interface condition oscillatory solution
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Role of outdoor trees on pedestrian wind and thermal conditions around a pre-education building for sustainable energy management
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作者 LI Xiao-jie TANG Hui-li 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第6期2039-2053,共15页
Finding sustainable energy resources is essential to face the increasing energy demand.Trees are an important part of ancient architecture but are becoming rare in urban areas.Trees can control and tune the pedestrian... Finding sustainable energy resources is essential to face the increasing energy demand.Trees are an important part of ancient architecture but are becoming rare in urban areas.Trees can control and tune the pedestrian-level wind velocity and thermal condition.In this study,a numerical investigation is employed to assess the role of trees planted in the windward direction of the building complex on the thermal and pedestrian wind velocity conditions around/inside a pre-education building located in the center of the complex.Compared to the previous studies(which considered only outside buildings),this work considers the effects of trees on microclimate change both inside/outside buildings.Effects of different parameters including the leaf area density and number of trees,number of rows,far-field velocity magnitude,and thermal condition around the main building are assessed.The results show that the flow velocity in the spacing between the first-row buildings is reduced by 30%-40% when the one-row trees with 2 m height are planted 15 m farther than the buildings.Furthermore,two rows of trees are more effective in higher velocities and reduce the maximum velocity by about 50%.The investigation shows that trees also could reduce the temperature by about 1℃around the building. 展开更多
关键词 sustainable management energy trees urban area thermal condition building
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Enhancing Erectile Function and Alleviating Andropause Symptoms: Clinical Efficacy of a Human Stem Cell Conditioned Medium Cream
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作者 Hoichi Amano 《Health》 2024年第7期626-634,共9页
Erectile dysfunction (ED) is increasingly prevalent in Japan, exceeding 30%, and increasing with age. Unhealthy lifestyle habits, obesity, insufficient exercise, and smoking have been implicated in its pathogenesis, a... Erectile dysfunction (ED) is increasingly prevalent in Japan, exceeding 30%, and increasing with age. Unhealthy lifestyle habits, obesity, insufficient exercise, and smoking have been implicated in its pathogenesis, along with endothelial dysfunction of the corpora cavernosa and impaired blood flow to the penis considered underlying factors. However, the current treatments are limited to Phosphodiesterase-5 (PDE5) inhibitors. ED is the primary symptom of andropathy. This study reports the clinical efficacy of human stem cell-conditioned medium cream for ED treatment. Ten men without underlying diseases suspected of andropause with ED (mean age 43.2 ± 4.4 y, Hb 15.2 ± 0.6 gm/dL, AST/ALT 30.2/37.9 ± 12.4/14.0, eGFR 82.7 ± 12.4 mL/min/1.73 m2) were targeted. The cream was applied twice daily to the genital and scrotal areas. The erectile hardness score (EHS), International Index of Erectile Function-5 (IIEF-5), and Aging Male Symptoms (AMS) scale were used to evaluate the participants before and 30 days after use, and the results were compared using paired t-tests. The post-use qualitative opinions were collected through interviews. Significant improvements were observed compared to baseline in the IIEF-5 (11.8 ± 4.6→17.2 ± 5.1, P < 0.001), and AMS (46.3 ± 6.7→37.6 ± 5.3, P < 0.001) scores post cream use. EHS did not show a statistically significant difference, but a trend towards improvement was observed. Qualitative feedback included increased morning erection, improved maintenance of erection during intercourse, and reduced post work fatigue. Human stem cell-conditioned medium contains endothelial growth factors that potentially contribute to the improvement of ED and andropause by enhancing corporal endothelial function. Future studies should include control groups to further investigate the efficacy of these treatments. 展开更多
关键词 Erectile Dysfunction ANDROPAUSE Human Stem Cell conditioned Medium Cream Stem Cell
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Research on shell-side heat and mass transfer with multi-component in LNG spiral-wound heat exchanger under sloshing conditions
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作者 Xue-Ping Du Guang-Lei Yu +3 位作者 Ya-Cheng Xu Zhi-Jie Chen Nai-Liang Li Huan-Guang Wang 《Petroleum Science》 SCIE EI CAS CSCD 2024年第2期1333-1345,共13页
The spiral-wound heat exchanger(SWHE) is the primary low-temperature heat exchanger for large-scale LNG plants due to its high-pressure resistance, compact structure, and high heat exchange efficiency. This paper stud... The spiral-wound heat exchanger(SWHE) is the primary low-temperature heat exchanger for large-scale LNG plants due to its high-pressure resistance, compact structure, and high heat exchange efficiency. This paper studied the shell-side heat and mass transfer characteristics of vapor-liquid two-phase mixed refrigerants in an SWHE by combining a multi-component model in FLUENT software with a customized multicomponent mass transfer model. Besides, the mathematical model under the sloshing condition was obtained through mathematical derivation, and the corresponding UDF code was loaded into FLUENT as the momentum source term. The results under the sloshing conditions were compared with the relevant parameters under the steady-state condition. The shell-side heat and mass transfer characteristics of the SWHE were investigated by adjusting the component ratio and other working conditions. It was found that the sloshing conditions enhance the heat transfer performance and sometimes have insignificant effects. The sloshing condition is beneficial to reduce the flow resistance. The comprehensive performance of multi-component refrigerants has been improved and the improvement is more significant under sloshing conditions, considering both the heat transfer and pressure drop.These results will provide theoretical support for the research and design of multi-component heat and mass transfer enhancement of LNG SWHE under ocean sloshing conditions. 展开更多
关键词 Spiral-wound heat exchanger Sloshing conditions Two-phase flow MULTI-COMPONENT Heat and mass transfer
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Conditional Generative Adversarial Network Enabled Localized Stress Recovery of Periodic Composites
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作者 Chengkan Xu Xiaofei Wang +2 位作者 Yixuan Li Guannan Wang He Zhang 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第7期957-974,共18页
Structural damage in heterogeneousmaterials typically originates frommicrostructures where stress concentration occurs.Therefore,evaluating the magnitude and location of localized stress distributions within microstru... Structural damage in heterogeneousmaterials typically originates frommicrostructures where stress concentration occurs.Therefore,evaluating the magnitude and location of localized stress distributions within microstructures under external loading is crucial.Repeating unit cells(RUCs)are commonly used to represent microstructural details and homogenize the effective response of composites.This work develops a machine learning-based micromechanics tool to accurately predict the stress distributions of extracted RUCs.The locally exact homogenization theory efficiently generates the microstructural stresses of RUCs with a wide range of parameters,including volume fraction,fiber/matrix property ratio,fiber shapes,and loading direction.Subsequently,the conditional generative adversarial network(cGAN)is employed and constructed as a surrogate model to establish the statistical correlation between these parameters and the corresponding localized stresses.The stresses predicted by cGAN are validated against the remaining true data not used for training,showing good agreement.This work demonstrates that the cGAN-based micromechanics tool effectively captures the local responses of composite RUCs.It can be used for predicting potential crack initiations starting from microstructures and evaluating the effective behavior of periodic composites. 展开更多
关键词 Periodic composites localized stress recovery conditional generative adversarial network
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Debaryomyces hansenii supplementation in low fish meal diets promotes growth,modulates microbiota and enhances intestinal condition in juvenile marine fish
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作者 Ignasi Sanahuja Alberto Ruiz +9 位作者 Joana P.Firmino Felipe E.Reyes-López Juan B.Ortiz-Delgado Eva Vallejos-Vidal Lluis Tort Dariel Tovar-Ramírez Isabel M.Cerezo Miguel A.Moriñigo Carmen Sarasquete Enric Gisbert 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第1期253-276,共24页
Background The development of a sustainable business model with social acceptance,makes necessary to develop new strategies to guarantee the growth,health,and well-being of farmed animals.Debaryomyces hansenii is a ye... Background The development of a sustainable business model with social acceptance,makes necessary to develop new strategies to guarantee the growth,health,and well-being of farmed animals.Debaryomyces hansenii is a yeast species that can be used as a probiotic in aquaculture due to its capacity to i)promote cell proliferation and differen-tiation,ii)have immunostimulatory effects,iii)modulate gut microbiota,and/or iv)enhance the digestive function.To provide inside into the effects of D.hansenii on juveniles of gilthead seabream(Sparus aurata)condition,we inte-grated the evaluation of the main key performance indicators coupled with the integrative analysis of the intestine condition,through histological and microbiota state,and its transcriptomic profiling.Results After 70 days of a nutritional trial in which a diet with low levels of fishmeal(7%)was supplemented with 1.1%of D.hansenii(17.2×10^(5) CFU),an increase of ca.12%in somatic growth was observed together with an improve-ment in feed conversion in fish fed a yeast-supplemented diet.In terms of intestinal condition,this probiotic modu-lated gut microbiota without affecting the intestine cell organization,whereas an increase in the staining intensity of mucins rich in carboxylated and weakly sulphated glycoconjugates coupled with changes in the affinity for certain lectins were noted in goblet cells.Changes in microbiota were characterized by the reduction in abundance of several groups of Proteobacteria,especially those characterized as opportunistic groups.The microarrays-based transcrip-tomic analysis found 232 differential expressed genes in the anterior-mid intestine of S.aurata,that were mostly related to metabolic,antioxidant,immune,and symbiotic processes.Conclusions Dietary administration of D.hansenii enhanced somatic growth and improved feed efficiency param-eters,results that were coupled to an improvement of intestinal condition as histochemical and transcriptomic tools indicated.This probiotic yeast stimulated host-microbiota interactions without altering the intestinal cell organization nor generating dysbiosis,which demonstrated its safety as a feed additive.At the transcriptomic level,D.hansenii pro-moted metabolic pathways,mainly protein-related,sphingolipid,and thymidylate pathways,in addition to enhance antioxidant-related intestinal mechanisms,and to regulate sentinel immune processes,potentiating the defensive capacity meanwhile maintaining the homeostatic status of the intestine. 展开更多
关键词 Debaryomyces hansenii Intestine condition Low fish meal diet MICROBIOTA TRANSCRIPTOMICS Yeast probiotic
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Impact of wetting-drying cycles and acidic conditions on the soil aggregate stability of yellow‒brown soil
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作者 XIA Zhenyao NI Yuanzhen +2 位作者 LIU Deyu WANG Di XIAO Hai 《Journal of Mountain Science》 SCIE CSCD 2024年第6期2075-2090,共16页
Soil aggregate is the basic structural unit of soil,which is the foundation for supporting ecosystem functions,while its composition and stability is significantly affected by the external environment.This study was c... Soil aggregate is the basic structural unit of soil,which is the foundation for supporting ecosystem functions,while its composition and stability is significantly affected by the external environment.This study was conducted to explore the effect of external environment(wetting-drying cycles and acidic conditions)on the soil aggregate distribution and stability and identify the key soil physicochemical factors that affect the soil aggregate stability.The yellow‒brown soil from the Three Gorges Reservoir area(TGRA)was used,and 8 wetting-drying conditions(0,1,2,3,4,5,10 and 15 cycles)were simulated under 4 acidic conditions(pH=3,4,5 and 7).The particle size distribution and soil aggregate stability were determined by wet sieving method,the contribution of environmental factors(acid condition,wetting-drying cycle and their combined action)to the soil aggregate stability was clarified and the key soil physicochemical factors that affect the soil aggregate stability under wetting-drying cycles and acidic conditions were determined by using the Pearson’s correlation analysis,Partial least squares path modeling(PLS‒PM)and multiple linear regression analysis.The results indicate that wetting-drying cycles and acidic conditions have significant effects on the stability of soil aggregates,the soil aggregate stability gradually decreases with increasing number of wetting-drying cycles and it obviously decreases with the increase of acidity.Moreover,the combination of wetting-drying cycles and acidic conditions aggravate the reduction in the soil aggregate stability.The wetting-drying cycles,acidic conditions and their combined effect imposes significant impact on the soil aggregate stability,and the wetting-drying cycles exert the greatest influence.The soil aggregate stability is significantly correlated with the pH,Ca^(2+),Mg^(2+),maximum disintegration index(MDI)and soil bulk density(SBD).The PLS‒PM and multiple linear regression analysis further reveal that the soil aggregate stability is primarily influenced by SBD,Ca^(2+),and MDI.These results offer a scientific basis for understanding the soil aggregate breakdown mechanism and are helpful for clarifying the coupled effect of wetting-drying cycles and acid rain on terrestrial ecosystems in the TGRA. 展开更多
关键词 Yellow‒brown soil Wetting-drying cycles Acidic conditions Soil aggregate stability Soil disintegration
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Working condition recognition of sucker rod pumping system based on 4-segment time-frequency signature matrix and deep learning
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作者 Yun-Peng He Hai-Bo Cheng +4 位作者 Peng Zeng Chuan-Zhi Zang Qing-Wei Dong Guang-Xi Wan Xiao-Ting Dong 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期641-653,共13页
High-precision and real-time diagnosis of sucker rod pumping system(SRPS)is important for quickly mastering oil well operations.Deep learning-based method for classifying the dynamometer card(DC)of oil wells is an eff... High-precision and real-time diagnosis of sucker rod pumping system(SRPS)is important for quickly mastering oil well operations.Deep learning-based method for classifying the dynamometer card(DC)of oil wells is an efficient diagnosis method.However,the input of the DC as a two-dimensional image into the deep learning framework suffers from low feature utilization and high computational effort.Additionally,different SRPSs in an oil field have various system parameters,and the same SRPS generates different DCs at different moments.Thus,there is heterogeneity in field data,which can dramatically impair the diagnostic accuracy.To solve the above problems,a working condition recognition method based on 4-segment time-frequency signature matrix(4S-TFSM)and deep learning is presented in this paper.First,the 4-segment time-frequency signature(4S-TFS)method that can reduce the computing power requirements is proposed for feature extraction of DC data.Subsequently,the 4S-TFSM is constructed by relative normalization and matrix calculation to synthesize the features of multiple data and solve the problem of data heterogeneity.Finally,a convolutional neural network(CNN),one of the deep learning frameworks,is used to determine the functioning conditions based on the 4S-TFSM.Experiments on field data verify that the proposed diagnostic method based on 4S-TFSM and CNN(4S-TFSM-CNN)can significantly improve the accuracy of working condition recognition with lower computational cost.To the best of our knowledge,this is the first work to discuss the effect of data heterogeneity on the working condition recognition performance of SRPS. 展开更多
关键词 Sucker-rod pumping system Dynamometer card Working condition recognition Deep learning Time-frequency signature Time-frequency signature matrix
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Impact of Initial Soil Conditions on Soil Hydrothermal and Surface Energy Fluxes in the Permafrost Region of the Tibetan Plateau
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作者 Siqiong LUO Zihang CHEN +3 位作者 Jingyuan WANG Tonghua WU Yao XIAO Yongping QIAO 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第4期717-736,共20页
Accurate initial soil conditions play a crucial role in simulating soil hydrothermal and surface energy fluxes in land surface process modeling.This study emphasized the influence of the initial soil temperature(ST)an... Accurate initial soil conditions play a crucial role in simulating soil hydrothermal and surface energy fluxes in land surface process modeling.This study emphasized the influence of the initial soil temperature(ST)and soil moisture(SM)conditions on a land surface energy and water simulation in the permafrost region in the Tibetan Plateau(TP)using the Community Land Model version 5.0(CLM5.0).The results indicate that the default initial schemes for ST and SM in CLM5.0 were simplistic,and inaccurately represented the soil characteristics of permafrost in the TP which led to underestimating ST during the freezing period while overestimating ST and underestimating SLW during the thawing period at the XDT site.Applying the long-term spin-up method to obtain initial soil conditions has only led to limited improvement in simulating soil hydrothermal and surface energy fluxes.The modified initial soil schemes proposed in this study comprehensively incorporate the characteristics of permafrost,which coexists with soil liquid water(SLW),and soil ice(SI)when the ST is below freezing temperature,effectively enhancing the accuracy of the simulated soil hydrothermal and surface energy fluxes.Consequently,the modified initial soil schemes greatly improved upon the results achieved through the long-term spin-up method.Three modified initial soil schemes experiments resulted in a 64%,88%,and 77%reduction in the average mean bias error(MBE)of ST,and a 13%,21%,and 19%reduction in the average root-mean-square error(RMSE)of SLW compared to the default simulation results.Also,the average MBE of net radiation was reduced by 7%,22%,and 21%. 展开更多
关键词 initial soil conditions soil temperature soil liquid water soil ice surface energy fluxes PERMAFROST
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Effect of boundary conditions on shakedown analysis of heterogeneous materials
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作者 Xiuchen GONG Yinghao NIE +1 位作者 Gengdong CHENG Kai LI 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第1期39-68,共30页
The determination of the ultimate load-bearing capacity of structures made of elastoplastic heterogeneous materials under varying loads is of great importance for engineering analysis and design. Therefore, it is nece... The determination of the ultimate load-bearing capacity of structures made of elastoplastic heterogeneous materials under varying loads is of great importance for engineering analysis and design. Therefore, it is necessary to accurately predict the shakedown domains of these materials. The static shakedown theorem, also known as Melan's theorem, is a fundamental method used to predict the shakedown domains of structures and materials. Within this method, a key aspect lies in the construction and application of an appropriate self-equilibrium stress field(SSF). In the structural shakedown analysis, the SSF is typically constructed by governing equations that satisfy no external force(NEF) boundary conditions. However, we discover that directly applying these governing equations is not suitable for the shakedown analysis of heterogeneous materials. Researchers must consider the requirements imposed by the Hill-Mandel condition for boundary conditions and the physical significance of representative volume elements(RVEs). This paper addresses this issue and demonstrates that the sizes of SSFs vary under different boundary conditions, such as uniform displacement boundary conditions(DBCs), uniform traction boundary conditions(TBCs), and periodic boundary conditions(PBCs). As a result, significant discrepancies arise in the predicted shakedown domain sizes of heterogeneous materials. Built on the demonstrated relationship between SSFs under different boundary conditions, this study explores the conservative relationships among different shakedown domains, and provides proof of the relationship between the elastic limit(EL) factors and the shakedown loading factors under the loading domain of two load vertices. By utilizing numerical examples, we highlight the conservatism present in certain results reported in the existing literature. Among the investigated boundary conditions, the obtained shakedown domain is the most conservative under TBCs.Conversely, utilizing PBCs to construct an SSF for the shakedown analysis leads to less conservative lower bounds, indicating that PBCs should be employed as the preferred boundary conditions for the shakedown analysis of heterogeneous materials. 展开更多
关键词 heterogeneous material self-equilibrium stress field(SSF) shakedown analysis effect of boundary conditions
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