Efficacy of Solution Form of Ethylenediaminetetraacetic Acid on Removing Smear Layer of Root Canal at Different Exposure Time In Vitro

Summary： This study was aimed to evaluate the effectiveness of solution form of 17% ethylenediaminetetraacetic acid （EDTA） on removing smear layer of root canals at different exposure time periods and to provide scientific basis for EDTA as a choice of root canal irrigation in clinical practice. Twenty-five single-rooted teeth were randomly divided into 5 groups： control group （group A） was given 2.5% NaOC1, and 4 experimental groups were given 2.5% NaOC1 and 17% EDTA, including groups B, C, D and E with exposure time of 1, 3, 5 and 7 min, respectively. After preparation of the root canals, the teeth were split along their longitudinal axis, and the root sections were examined under scanning elec- tron microscope for evaluation of smear layer removal and erosion on the surface of the root canal walls. The specimens in group B showed presence of smear layer on the walls of the root canal with no statistical difference from that in group A （P〉0.05）. In groups C and D, partial removal of smear layer was obtained, and there was no significant difference between the two groups （P〉0.05）, but there was significant difference in removal of smear layer between group C and group B （P〈0.05）. Root canal walls in group E specimens showed almost complete removal of smear layer, and the removal of smear layer was significantly different from that in group D （P〈0.01）. There was no significant change in the structure of the surface of root canal for each sample. It was concluded that combined irrigation with 17% EDTA and 2.5% NaOC1 could remove the smear layer with no significant alteration in dentinal structure when the chelating agent was applied for 7 min. At 3 and 5 min of application, partial removal of smear layer was observed and at 1 min negligible removal of smear layer was achieved.

Endodontic irrigants from a comprehensive perspective

This review article explores the fundamental principles of modern endodontics with a focus on root canal cleaning and shaping.It reviews commonly used endodontic irrigant,namely sodium hypochlorite(NaOCl),herbal extracts,chlorhexidine(CHX),and chelating agents,highlighting their properties,applications,and potential drawbacks.NaOCl,a key antimicrobial agent,demonstrates effectiveness against various microorganisms but poses challenges such as high cytotoxicity.Herbal extracts,gaining recognition in endodontics,present an alternative with potential advantages in preserving dentin integrity.CHX,known for its broad-spectrum antimicrobial activity,is discussed in both liquid and gel formulations,emphasizing its role in reducing smear layer formation and preserving hybrid layer durability.Chelating agents,specifically ethylenediaminetetraacetic acid and citric acid,play a vital role in removing the smear layer,enhancing dentin permeability,and facilitating the penetration of antimicrobial agents.The review article underscores the importance of careful application and consideration of each irrigant's properties to ensure safe and effective endodontic procedures.It serves as a valuable guide for clinicians in selecting appropriate irrigants based on specific treatment requirements.

超声荡洗对根管预备后疼痛及疗程的影响

目的探讨超声荡洗对根管预备后疼痛及疗程的影响。方法采用临床对照研究的方法,将40例牙髓根尖周病患者随机分为超声荡洗组和注射器冲洗组,观察两组根管预备后疼痛程度及疗程。结果对于慢性根尖周炎患者,超声荡洗组在根管预备后疼痛和患者的复诊次数上分别轻于及少于注射器冲洗组(P<0.05);对于慢性牙髓炎患者,两组在根管预备后疼痛和复诊次数上差异均无统计学意义(P>0.05)。结论在根管预备过程中,采用超声荡洗,能够减轻慢性根尖周炎患者根管预备后出现的局部疼痛,同时减少患者根管治疗复诊次数。