【目的】探讨血清S-100B蛋白浓度作为HIE早期诊断的价值。【方法】对52例新生儿分别采集脐血、生后12、24 h静脉血,采用ELISA法测定血清中S-100B蛋白的浓度水平。【结果】对照组与窒息组各时间段血清S-100B蛋白浓度差异均有显著性(P<...【目的】探讨血清S-100B蛋白浓度作为HIE早期诊断的价值。【方法】对52例新生儿分别采集脐血、生后12、24 h静脉血,采用ELISA法测定血清中S-100B蛋白的浓度水平。【结果】对照组与窒息组各时间段血清S-100B蛋白浓度差异均有显著性(P<0.01)。窒息新生儿无HIE组和有HIE组比较脐血S-100B蛋白浓度差异无显著性(P>0.05);12 h和24 h段差异均有显著性(P<0.05)。12 h和S-100B蛋白浓度(界值≥2.86μg/L)对判断中重度HIE有较高的特异度、灵敏度、阳性预测值和阴性预测值;1 min Apgar评分与12 h S-100B蛋白浓度之间呈负相关。【结论】血清S-100B蛋白浓度可以作为早期诊断HIE,并判断HIE严重程度的有效指标。展开更多
<span style="font-family:Verdana;"><strong>Background:</strong> Herbal medicines use has prevailed over the past decades in both low-middle-income and high-income countries over the years. ...<span style="font-family:Verdana;"><strong>Background:</strong> Herbal medicines use has prevailed over the past decades in both low-middle-income and high-income countries over the years. The use among women has increased with increased risks of ill-health. There is extensive literature on herbal medicine use among women in pre/pregnancy, labour, and the postpartum periods. Therefore, this study aimed to understand women’s purposes, experiences, and motivation for using herbal medicines during pregnancy, childbirth and postpartum, and the experiences associated with the use. <strong>Methods:</strong> Four critical databases were predetermined and searched: CINAHL, Medline, Web of Science, and EMBASE. These databases were chosen for their comprehensiveness and relevance to the review aims. We considered peer-reviewed published articles from January 2000 to December 2018. We chose these databases because we found that they are dominant in the medical and healthcare-related literature. All references were pooled to Endnote reference management software for screening. Quality appraisal of articles was conducted using the Mixed-Method Assessment Tool (MMAT). Content analysis approach was used to extra the data from the articles. Globally, twenty-one articles met the inclusion criteria, and thus, formed the dataset for this review.<strong> Results:</strong> Most articles (n = 10, 47.6%) reported solely HM uses on only pregnancy whiles the rest evaluated HM uses in labour, pre-pregnancy, and the postpartum periods. The results have shown that the majority of women received information about HM from friends, family, the “black markets,” and drug outlets. Overall, the results were presented in seven broad themes: 1) sociodemographic characteristics of HM users, 2) perceived threat of health problem, 3) sources and quality of the information received, 4) susceptibility to health complications, 5) potential limitations to the use of HM, 6) the motivation for HM utilization, 7) concerns on the combined use of herbal and allopathic medicines. <strong>Conclusion:</strong> The study recommends the further research into the toxicity of herbal products, to ensure that accurate information can be provided to women before use.</span>展开更多
文摘【目的】探讨血清S-100B蛋白浓度作为HIE早期诊断的价值。【方法】对52例新生儿分别采集脐血、生后12、24 h静脉血,采用ELISA法测定血清中S-100B蛋白的浓度水平。【结果】对照组与窒息组各时间段血清S-100B蛋白浓度差异均有显著性(P<0.01)。窒息新生儿无HIE组和有HIE组比较脐血S-100B蛋白浓度差异无显著性(P>0.05);12 h和24 h段差异均有显著性(P<0.05)。12 h和S-100B蛋白浓度(界值≥2.86μg/L)对判断中重度HIE有较高的特异度、灵敏度、阳性预测值和阴性预测值;1 min Apgar评分与12 h S-100B蛋白浓度之间呈负相关。【结论】血清S-100B蛋白浓度可以作为早期诊断HIE,并判断HIE严重程度的有效指标。
文摘<span style="font-family:Verdana;"><strong>Background:</strong> Herbal medicines use has prevailed over the past decades in both low-middle-income and high-income countries over the years. The use among women has increased with increased risks of ill-health. There is extensive literature on herbal medicine use among women in pre/pregnancy, labour, and the postpartum periods. Therefore, this study aimed to understand women’s purposes, experiences, and motivation for using herbal medicines during pregnancy, childbirth and postpartum, and the experiences associated with the use. <strong>Methods:</strong> Four critical databases were predetermined and searched: CINAHL, Medline, Web of Science, and EMBASE. These databases were chosen for their comprehensiveness and relevance to the review aims. We considered peer-reviewed published articles from January 2000 to December 2018. We chose these databases because we found that they are dominant in the medical and healthcare-related literature. All references were pooled to Endnote reference management software for screening. Quality appraisal of articles was conducted using the Mixed-Method Assessment Tool (MMAT). Content analysis approach was used to extra the data from the articles. Globally, twenty-one articles met the inclusion criteria, and thus, formed the dataset for this review.<strong> Results:</strong> Most articles (n = 10, 47.6%) reported solely HM uses on only pregnancy whiles the rest evaluated HM uses in labour, pre-pregnancy, and the postpartum periods. The results have shown that the majority of women received information about HM from friends, family, the “black markets,” and drug outlets. Overall, the results were presented in seven broad themes: 1) sociodemographic characteristics of HM users, 2) perceived threat of health problem, 3) sources and quality of the information received, 4) susceptibility to health complications, 5) potential limitations to the use of HM, 6) the motivation for HM utilization, 7) concerns on the combined use of herbal and allopathic medicines. <strong>Conclusion:</strong> The study recommends the further research into the toxicity of herbal products, to ensure that accurate information can be provided to women before use.</span>
