Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson＇s disease. Programming of the stimulation parameters is important for maintaining th...Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson＇s disease. Programming of the stimulation parameters is important for maintaining the efficacy of deep brain stimulation. Voltage is consid- ered to be the most effective programming parameter. The present study is a retrospective analysis of six patients with Parkinson＇s disease （four men and two women, aged 37-65 years）, who underwent bilateral deep brain stimulation of the subthalamic nucleus at the First Affiliated Hospital of Sun Yat-sen University, China, and who subsequently adjusted only the stimulation voltage. We evaluated motor symptom severity using the Unified Parkinson＇s Disease Rating Scale Part III, symptom progression using the Hoehn and Yahr scale, and the levodopa equivalent daily dose, before surgery and 1 and 2 years after surgery. The 2-year follow-up results show that rigidity and tremor improved, and clinical symptoms were reduced, while pulse width was maintained at 60 ps and frequency at 130 Hz. Voltage adjust- ment alone is particularly suitable for patients who cannot tolerate multiparameter program adjustment. Levodopa equivalent daily dose was markedly reduced 1 and 2 years after surgery compared with baseline. Our results confirm that rigidity, tremor and bradykinesia can be best alleviated by voltage adjustment. The trial was registered at ClinicalTrials.gov （identifier： NCT01934881）.展开更多
The Earth is taken as a triaxial rigid body, which rotates freely in the Euclidian space. The starting equations are the Euler dynamic equations, with A smaller than B and B smaller than C. The Euler equations are sol...The Earth is taken as a triaxial rigid body, which rotates freely in the Euclidian space. The starting equations are the Euler dynamic equations, with A smaller than B and B smaller than C. The Euler equations are solved, and the numerical results are provided. In the calculations, the following parameters are used: (C-B)/A=0.003 273 53; (B-A)/C=0.000 021 96; (C-A)/B=0.003 295 49, and the mean angular velocity of the Earth's rotation, ω =0.000 072 921 15 rad/s. Calculations show that, besides the self-rotation of the Earth and the free Euler procession of its rotation, there exists the free nutation: the nutation angle, or the angle between the Earth's momentary rotation axis and the mean axis that periodically change with time. The free nutation is investigated.展开更多
In this paper the method of design of kinematical and dynamical equations of mechanical systems, applied to numerical ealization, is proposed. The corresponding difference equations, which are obtained, give a guarant...In this paper the method of design of kinematical and dynamical equations of mechanical systems, applied to numerical ealization, is proposed. The corresponding difference equations, which are obtained, give a guarantee of computations with a given precision. The equations of programmed constraints and those of constraint perturbations are defined. The stability of the programmed manifold for numerical solutions of the kinematical and dynamical equations is obtained by corresponding construction of the constraint perturbation equations. The dynamical equations of system with programmed constraints are set up in the form of Lagrange’s equations in generalized coordinates. Certain inverse problems of rigid body dynamics are examined.展开更多
In the present paper a vibrational differential equation governing on a rigid beam on viscoelastic foundation has been investigated. The nonlinear differential equation governing on this vibrating system is solved by ...In the present paper a vibrational differential equation governing on a rigid beam on viscoelastic foundation has been investigated. The nonlinear differential equation governing on this vibrating system is solved by a simple and innovative approach, which has been called Akbari-Ganji＇s method （AGM）. AGM is a very suitable computational process and is usable for solving various nonlinear differential equations. Moreover, using AGM which solving a set of algebraic equations, complicated nonlinear equations can easily be solved without any mathematical operations. Also, the damping ratio and energy lost per cycle for three cycles have been investigated. Furthermore, comparisons have been made between the obtained results by numerical method （Runk45） and AGM. Results showed the high accuracy of AGM. The results also showed that by increasing the amount of initial amplitude of vibration （A）, the value of damping ratio will be increased, and the energy lost per cycle decreases by increasing the number of cycle. It is concluded that AGM is a reliable and precise approach for solving differential equations. On the other hand, it is better to say that AGM is able to solve linear and nonlinear differential equations directly in most of the situations. This means that the final solution can be obtained without any dimensionless procedure Therefore, AGM can be considered as a significant progress in nonlinear sciences.展开更多
In this paper we compute general-relativistic polytropic models simulating rigidly rotating, pulsating neutron stars. These relativistic compact objects, with a radius of ~10 km and mass between ~1.4 and 3.2 solar mas...In this paper we compute general-relativistic polytropic models simulating rigidly rotating, pulsating neutron stars. These relativistic compact objects, with a radius of ~10 km and mass between ~1.4 and 3.2 solar masses, are closely related to pulsars. We emphasize on computing the change in the pulsation eigenfrequencies owing to a rigid rotation, which, in turn, is a decisive issue for studying stability of such objects. In our computations, we keep rotational perturbation terms of up to second order in the angular velocity.展开更多
The development of a possible slip line field (slf) for theoretical calculations of the deforming pressure (load) in a second pass of a lubricated cold rolling sheet mill and validation using values from an aluminium ...The development of a possible slip line field (slf) for theoretical calculations of the deforming pressure (load) in a second pass of a lubricated cold rolling sheet mill and validation using values from an aluminium sheet rolling mill was done in this work. This will be relevant in the manufacturing industries providing an easy method for determining necessary applied rolling load. Experimental rolling was carried out to observe the shear lines in the deformation field. Construction of possible slip line field model was developed adhering strictly to assumptions of rigid plastic model. Calculation of the deforming force/load was achieved using Hencky’s equation. Results showed that the load calculations for constructed slip line field using aluminium sheet rolling as an example tallied with values obtained from Tower Aluminium rolling mill. Slip line fields constructed for the second pass described adequately the rolling pressure in the cold rolling process, giving a valid solution of the exact load estimates on comparison with the industrial load values. Roll pressure along the arc of contact rose fairly linearly from the entrance to a maximum at the exit point. This work showed that slf for the first pass in a cold rolling mill cannot be used for subsequent passes;it requires construction of slfs for each pass in the cold rolling process.展开更多
Rigid ellipsoidal objects(gravels and porphyroclasts)in ductile zone is an important factor to indicate the kinematics and dynamics.Jeffery’s theory(Jeffery G,1922),a quantitative research method,for the rotation oft...Rigid ellipsoidal objects(gravels and porphyroclasts)in ductile zone is an important factor to indicate the kinematics and dynamics.Jeffery’s theory(Jeffery G,1922),a quantitative research method,for the rotation ofthe rigid objects(no deformation)in the Newtonian fluid of the simple deformation field has been widely applied by geologists to the study of fabrics in rocks.The theory展开更多
Seismic oscillations of the “building-building” system which is interconnected buildings built close to each other, and “building-stack-like structure” system which is adjacent and connected in different ways to e...Seismic oscillations of the “building-building” system which is interconnected buildings built close to each other, and “building-stack-like structure” system which is adjacent and connected in different ways to existing building are considered in the paper. Different types of connections, such as dampers, including the ones suggested by the authors, are studied. Seismic impact is given as a harmonic function and various existing accelerograms, including synthesized ones. Distinctive feature of this paper from previously published ones [1] [2] is the fact that the emphasis falls on the influence of soil-foundation interaction properties, which are described using various models of load-displacement connections. Calculation results are compared in the case of representation of the building as concentrated masses and spatial systems. Ways to reduce seismic response of buildings during the earthquakes are pointed out. Results of experimental studies are given in the paper and are compared with calculations.展开更多
基金supported by the Science and Technology Foundation of Guangdong Province of China,No.2014A030304019the Natural Science Foundation of Guangdong Province of China,No.2015A030313164
文摘Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson＇s disease. Programming of the stimulation parameters is important for maintaining the efficacy of deep brain stimulation. Voltage is consid- ered to be the most effective programming parameter. The present study is a retrospective analysis of six patients with Parkinson＇s disease （four men and two women, aged 37-65 years）, who underwent bilateral deep brain stimulation of the subthalamic nucleus at the First Affiliated Hospital of Sun Yat-sen University, China, and who subsequently adjusted only the stimulation voltage. We evaluated motor symptom severity using the Unified Parkinson＇s Disease Rating Scale Part III, symptom progression using the Hoehn and Yahr scale, and the levodopa equivalent daily dose, before surgery and 1 and 2 years after surgery. The 2-year follow-up results show that rigidity and tremor improved, and clinical symptoms were reduced, while pulse width was maintained at 60 ps and frequency at 130 Hz. Voltage adjust- ment alone is particularly suitable for patients who cannot tolerate multiparameter program adjustment. Levodopa equivalent daily dose was markedly reduced 1 and 2 years after surgery compared with baseline. Our results confirm that rigidity, tremor and bradykinesia can be best alleviated by voltage adjustment. The trial was registered at ClinicalTrials.gov （identifier： NCT01934881）.
基金Funded by the National Natural Science Foundation of China (No.40574004).
文摘The Earth is taken as a triaxial rigid body, which rotates freely in the Euclidian space. The starting equations are the Euler dynamic equations, with A smaller than B and B smaller than C. The Euler equations are solved, and the numerical results are provided. In the calculations, the following parameters are used: (C-B)/A=0.003 273 53; (B-A)/C=0.000 021 96; (C-A)/B=0.003 295 49, and the mean angular velocity of the Earth's rotation, ω =0.000 072 921 15 rad/s. Calculations show that, besides the self-rotation of the Earth and the free Euler procession of its rotation, there exists the free nutation: the nutation angle, or the angle between the Earth's momentary rotation axis and the mean axis that periodically change with time. The free nutation is investigated.
基金Supported by Russian Fund of Fund amental Investigations(Pr.990101064)and Russian Minister of Educatin
文摘In this paper the method of design of kinematical and dynamical equations of mechanical systems, applied to numerical ealization, is proposed. The corresponding difference equations, which are obtained, give a guarantee of computations with a given precision. The equations of programmed constraints and those of constraint perturbations are defined. The stability of the programmed manifold for numerical solutions of the kinematical and dynamical equations is obtained by corresponding construction of the constraint perturbation equations. The dynamical equations of system with programmed constraints are set up in the form of Lagrange’s equations in generalized coordinates. Certain inverse problems of rigid body dynamics are examined.
文摘In the present paper a vibrational differential equation governing on a rigid beam on viscoelastic foundation has been investigated. The nonlinear differential equation governing on this vibrating system is solved by a simple and innovative approach, which has been called Akbari-Ganji＇s method （AGM）. AGM is a very suitable computational process and is usable for solving various nonlinear differential equations. Moreover, using AGM which solving a set of algebraic equations, complicated nonlinear equations can easily be solved without any mathematical operations. Also, the damping ratio and energy lost per cycle for three cycles have been investigated. Furthermore, comparisons have been made between the obtained results by numerical method （Runk45） and AGM. Results showed the high accuracy of AGM. The results also showed that by increasing the amount of initial amplitude of vibration （A）, the value of damping ratio will be increased, and the energy lost per cycle decreases by increasing the number of cycle. It is concluded that AGM is a reliable and precise approach for solving differential equations. On the other hand, it is better to say that AGM is able to solve linear and nonlinear differential equations directly in most of the situations. This means that the final solution can be obtained without any dimensionless procedure Therefore, AGM can be considered as a significant progress in nonlinear sciences.
文摘In this paper we compute general-relativistic polytropic models simulating rigidly rotating, pulsating neutron stars. These relativistic compact objects, with a radius of ~10 km and mass between ~1.4 and 3.2 solar masses, are closely related to pulsars. We emphasize on computing the change in the pulsation eigenfrequencies owing to a rigid rotation, which, in turn, is a decisive issue for studying stability of such objects. In our computations, we keep rotational perturbation terms of up to second order in the angular velocity.
文摘The development of a possible slip line field (slf) for theoretical calculations of the deforming pressure (load) in a second pass of a lubricated cold rolling sheet mill and validation using values from an aluminium sheet rolling mill was done in this work. This will be relevant in the manufacturing industries providing an easy method for determining necessary applied rolling load. Experimental rolling was carried out to observe the shear lines in the deformation field. Construction of possible slip line field model was developed adhering strictly to assumptions of rigid plastic model. Calculation of the deforming force/load was achieved using Hencky’s equation. Results showed that the load calculations for constructed slip line field using aluminium sheet rolling as an example tallied with values obtained from Tower Aluminium rolling mill. Slip line fields constructed for the second pass described adequately the rolling pressure in the cold rolling process, giving a valid solution of the exact load estimates on comparison with the industrial load values. Roll pressure along the arc of contact rose fairly linearly from the entrance to a maximum at the exit point. This work showed that slf for the first pass in a cold rolling mill cannot be used for subsequent passes;it requires construction of slfs for each pass in the cold rolling process.
文摘Rigid ellipsoidal objects(gravels and porphyroclasts)in ductile zone is an important factor to indicate the kinematics and dynamics.Jeffery’s theory(Jeffery G,1922),a quantitative research method,for the rotation ofthe rigid objects(no deformation)in the Newtonian fluid of the simple deformation field has been widely applied by geologists to the study of fabrics in rocks.The theory
文摘Seismic oscillations of the “building-building” system which is interconnected buildings built close to each other, and “building-stack-like structure” system which is adjacent and connected in different ways to existing building are considered in the paper. Different types of connections, such as dampers, including the ones suggested by the authors, are studied. Seismic impact is given as a harmonic function and various existing accelerograms, including synthesized ones. Distinctive feature of this paper from previously published ones [1] [2] is the fact that the emphasis falls on the influence of soil-foundation interaction properties, which are described using various models of load-displacement connections. Calculation results are compared in the case of representation of the building as concentrated masses and spatial systems. Ways to reduce seismic response of buildings during the earthquakes are pointed out. Results of experimental studies are given in the paper and are compared with calculations.
