基于中国保险汽车安全指数25%偏置碰撞工况,对某新能源汽车A柱的结构设计方案进行了研究。对比分析了基础结构、复合车身解决方案(Composite Body Solutions,CBS)胶块增强结构、热气胀形管梁增强结构对碰撞安全性的影响,介绍了CBS胶块...基于中国保险汽车安全指数25%偏置碰撞工况,对某新能源汽车A柱的结构设计方案进行了研究。对比分析了基础结构、复合车身解决方案(Composite Body Solutions,CBS)胶块增强结构、热气胀形管梁增强结构对碰撞安全性的影响,介绍了CBS胶块和热气胀形的制造工艺,并对热气胀形工艺进行了仿真分析,对比分析2种增强结构的工装投入和单件成本。研究发现,在均能实现小偏置碰撞安全性优秀等级的前提下,1500 MPa热气胀管梁方案在单件成本及轻量化方面比CBS胶块方案更具优势。展开更多
Complicated geological structures make it difficult to analyze the stability of rock slopes, such as faults, weak intercalated layers or joint fissures. Based on 3D geological modeling and surface block identifying me...Complicated geological structures make it difficult to analyze the stability of rock slopes, such as faults, weak intercalated layers or joint fissures. Based on 3D geological modeling and surface block identifying methods, an integrated methodology framework was proposed and realized to analyze the stability of surface blocks in rock slopes. The surface blocks cut by geological structures, fissures or free faces could be identified subjected to the four principles of closure, completeness, uniqueness and validity. The factor of safety(FOS)of single key block was calculated by the limit equilibrium method. If there were two or more connected blocks, they were defined as a block-group. The FOS of a block-group was computed by the Sarma method. The proposed approach was applied to an actual rock slope of a hydropower project, and some possible instable blocks were demonstrated and analyzed visually. The obtained results on the key blocks or block-groups provide essential information for determining potential instable region of rock slopes and designing effective support scheme in advance.展开更多
There are a lot of security issues in block cipher algorithm.Security analysis and enhanced design of a dynamic block cipher was proposed.Firstly,the safety of ciphertext was enhanced based on confusion substitution o...There are a lot of security issues in block cipher algorithm.Security analysis and enhanced design of a dynamic block cipher was proposed.Firstly,the safety of ciphertext was enhanced based on confusion substitution of S-box,thus disordering the internal structure of data blocks by four steps of matrix transformation.Then,the diffusivity of ciphertext was obtained by cyclic displacement of bytes using column ambiguity function.The dynamic key was finally generated by using LFSR,which improved the stochastic characters of secret key in each of round of iteration.The safety performance of proposed algorithm was analyzed by simulation test.The results showed the proposed algorithm has a little effect on the speed of encryption and decryption while enhancing the security.Meanwhile,the proposed algorithm has highly scalability,the dimension of S-box and the number of register can be dynamically extended according to the security requirement.展开更多
Sugammadex has revolutionized anaesthetic management of reversal of neuromuscular block(NMB) by way of its unique mechanism of action encapsulating the amino steroid neuromuscular blocking drugs rocuroniumand vecuroni...Sugammadex has revolutionized anaesthetic management of reversal of neuromuscular block(NMB) by way of its unique mechanism of action encapsulating the amino steroid neuromuscular blocking drugs rocuroniumand vecuronium. The cholinesterase inhibitors have significant pharmacological and clinical limitations whereas sugammadex allows predictable, safe and rapid reversal from any depth of blockade. The financial cost of sugammadex is significant. Many hospitals in the United Kingdom use clinical guidelines to direct best use of sugammadex in their institutions. Auditing the use of sugammadex provides useful information on which patients are benefiting from sugammadex. The clinical benefits of sugammadex are well understood. No patient should now be subjected to the danger of post-operative residual curarization. Versatility in the ability to reverse NMB has brought opportunities to the anaesthetist in the management of rapid sequence induction using high dose rocuronium with the knowledge that safe reversal of NMB is now possible in the unlikely event of a "can't intubate can't ventilate" situation. Do we still need suxamethonium to be available? The nature of surgery continues to evolve with ever-increasing enthusiasm for minimally invasive laparoscopic techniques. There is evidence to support using a deeper level of NMB to improve the working space and operating conditions in laparoscopic surgery. It is now possible to maintain a deep level of NMB right up until the end of surgery with no concerns about the ability to effect safe reversal of NMB. Vigilance about the possibility of allergic sensitivity to sugammadex needs to be maintained. The increased usage of rocuronium has the potential for rocuroniuminduced anaphylaxis. Conversely, there is a potential role for sugammadex in the treatment of rocuronium anaphylaxis. Clinicians who have used sugammadex are struck with the quality of recovery seen in their patients. It is important that the economic implications of the use of sugammadex are fully understood. This article considers the current role of sugammadex in clinical practice outside of routine reversal of NMB and discusses how the addition of sugammadex to the anaesthetic armamentarium brings safety benefits for patients.展开更多
文摘基于中国保险汽车安全指数25%偏置碰撞工况,对某新能源汽车A柱的结构设计方案进行了研究。对比分析了基础结构、复合车身解决方案(Composite Body Solutions,CBS)胶块增强结构、热气胀形管梁增强结构对碰撞安全性的影响,介绍了CBS胶块和热气胀形的制造工艺,并对热气胀形工艺进行了仿真分析,对比分析2种增强结构的工装投入和单件成本。研究发现,在均能实现小偏置碰撞安全性优秀等级的前提下,1500 MPa热气胀管梁方案在单件成本及轻量化方面比CBS胶块方案更具优势。
基金Supported by the National Natural Science Foundation of China(No.51379006 and No.51321065)the Program for New Century Excellent Talents in University of Ministry of Education of China(NCET-12-0404)
文摘Complicated geological structures make it difficult to analyze the stability of rock slopes, such as faults, weak intercalated layers or joint fissures. Based on 3D geological modeling and surface block identifying methods, an integrated methodology framework was proposed and realized to analyze the stability of surface blocks in rock slopes. The surface blocks cut by geological structures, fissures or free faces could be identified subjected to the four principles of closure, completeness, uniqueness and validity. The factor of safety(FOS)of single key block was calculated by the limit equilibrium method. If there were two or more connected blocks, they were defined as a block-group. The FOS of a block-group was computed by the Sarma method. The proposed approach was applied to an actual rock slope of a hydropower project, and some possible instable blocks were demonstrated and analyzed visually. The obtained results on the key blocks or block-groups provide essential information for determining potential instable region of rock slopes and designing effective support scheme in advance.
基金supported in part by National Natural Science Fundation of China under Grant No.61202458,61403109
文摘There are a lot of security issues in block cipher algorithm.Security analysis and enhanced design of a dynamic block cipher was proposed.Firstly,the safety of ciphertext was enhanced based on confusion substitution of S-box,thus disordering the internal structure of data blocks by four steps of matrix transformation.Then,the diffusivity of ciphertext was obtained by cyclic displacement of bytes using column ambiguity function.The dynamic key was finally generated by using LFSR,which improved the stochastic characters of secret key in each of round of iteration.The safety performance of proposed algorithm was analyzed by simulation test.The results showed the proposed algorithm has a little effect on the speed of encryption and decryption while enhancing the security.Meanwhile,the proposed algorithm has highly scalability,the dimension of S-box and the number of register can be dynamically extended according to the security requirement.
文摘Sugammadex has revolutionized anaesthetic management of reversal of neuromuscular block(NMB) by way of its unique mechanism of action encapsulating the amino steroid neuromuscular blocking drugs rocuroniumand vecuronium. The cholinesterase inhibitors have significant pharmacological and clinical limitations whereas sugammadex allows predictable, safe and rapid reversal from any depth of blockade. The financial cost of sugammadex is significant. Many hospitals in the United Kingdom use clinical guidelines to direct best use of sugammadex in their institutions. Auditing the use of sugammadex provides useful information on which patients are benefiting from sugammadex. The clinical benefits of sugammadex are well understood. No patient should now be subjected to the danger of post-operative residual curarization. Versatility in the ability to reverse NMB has brought opportunities to the anaesthetist in the management of rapid sequence induction using high dose rocuronium with the knowledge that safe reversal of NMB is now possible in the unlikely event of a "can't intubate can't ventilate" situation. Do we still need suxamethonium to be available? The nature of surgery continues to evolve with ever-increasing enthusiasm for minimally invasive laparoscopic techniques. There is evidence to support using a deeper level of NMB to improve the working space and operating conditions in laparoscopic surgery. It is now possible to maintain a deep level of NMB right up until the end of surgery with no concerns about the ability to effect safe reversal of NMB. Vigilance about the possibility of allergic sensitivity to sugammadex needs to be maintained. The increased usage of rocuronium has the potential for rocuroniuminduced anaphylaxis. Conversely, there is a potential role for sugammadex in the treatment of rocuronium anaphylaxis. Clinicians who have used sugammadex are struck with the quality of recovery seen in their patients. It is important that the economic implications of the use of sugammadex are fully understood. This article considers the current role of sugammadex in clinical practice outside of routine reversal of NMB and discusses how the addition of sugammadex to the anaesthetic armamentarium brings safety benefits for patients.
