The period since the 18th National Congress of the Communist Party of China(CPC)has witnessed the emerging of innovative achievements in traditional Chinese medicine(TCM).To fulfill the requirements proposed at the 20...The period since the 18th National Congress of the Communist Party of China(CPC)has witnessed the emerging of innovative achievements in traditional Chinese medicine(TCM).To fulfill the requirements proposed at the 20th National Congress of the CPC and in the Opinions of the CPC Central Committee and the State Council on Promoting the Preservation,Innovation,and Development of Traditional ChineseMedicine and give play to the demonstrative role ofmajor research achievements,the China Association of ChineseMedicine has organized TCM researchers and practitioners to comprehensively review the major research achievements in TCM since the 18th National Congress of the CPC.After collection and organization of achievements,report writing,expert evaluation,and public opinion soliciting,we have compiled the Remarkable Research Achievements of Traditional Chinese Medicine during 2012–2022.展开更多
Existing traditional Chinese medicine(TCM)-related databases are still insufficient in data standardization,integrity and precision,and need to be updated urgently.Herein,an Encyclopedia of Traditional Chinese Medicin...Existing traditional Chinese medicine(TCM)-related databases are still insufficient in data standardization,integrity and precision,and need to be updated urgently.Herein,an Encyclopedia of Traditional Chinese Medicine version 2.0(ETCM v2.0,http://www.tcmip.cn/ETCM2/front/#/)was constructed as the latest curated database hosting 48,442 TCM formulas recorded by ancient Chinese medical books,9872 Chinese patent drugs,2079 Chinese medicinal materials and 38,298 ingredients.To facilitate the mechanistic research and new drug discovery,we improved the target identification method based on a two-dimensional ligand similarity search module,which provides the confirmed and/or potential targets of each ingredient,as well as their binding activities.Importantly,five TCM formulas/Chinese patent drugs/herbs/ingredients with the highest Jaccard similarity scores to the submitted drugs are offered in ETCM v2.0,which may be of significance to identify prescriptions/herbs/ingredients with similar clinical efficacy,to summarize the rules of prescription use,and to find alternative drugs for endangered Chinese medicinal materials.Moreover,ETCM v2.0 provides an enhanced Java Script-based network visualization tool for creating,modifying and exploring multi-scale biological networks.ETCM v2.0 may be a major data warehouse for the quality marker identification of TCMs,the TCM-derived drug discovery and repurposing,and the pharmacological mechanism investigation of TCMs against various human diseases.展开更多
A brief survey and prospect on the research of the quality of traditional Chinese medicinal materials by means of plant ecology is given in this paper. It is concluded that the new methods and accomplish ment in plant...A brief survey and prospect on the research of the quality of traditional Chinese medicinal materials by means of plant ecology is given in this paper. It is concluded that the new methods and accomplish ment in plant ecology,combined with other related subjects,should be used fully in this research.Such combination might result in some new disciphines.展开更多
基金This work was supported by the Research Projects on Key Development Issues and Scientific Layout Strategies for Traditional Chinese Medicine(grant number:GZY-KJS-2023-047)National Overall Scientific and Technological Capabilities Third-Party Evaluation-Assessment Project on the Foundational Science Progress for the Modernization of Traditional ChineseMedicine(grant number:2023-pgsdx-35).
文摘The period since the 18th National Congress of the Communist Party of China(CPC)has witnessed the emerging of innovative achievements in traditional Chinese medicine(TCM).To fulfill the requirements proposed at the 20th National Congress of the CPC and in the Opinions of the CPC Central Committee and the State Council on Promoting the Preservation,Innovation,and Development of Traditional ChineseMedicine and give play to the demonstrative role ofmajor research achievements,the China Association of ChineseMedicine has organized TCM researchers and practitioners to comprehensively review the major research achievements in TCM since the 18th National Congress of the CPC.After collection and organization of achievements,report writing,expert evaluation,and public opinion soliciting,we have compiled the Remarkable Research Achievements of Traditional Chinese Medicine during 2012–2022.
基金supported by Key project at the National Natural Science Foundation of China(Grant Nos.81830111 and 82030122,China)the Innovation Project of China Academy of Chinese Medical Sciences(Grant No.CI2021A04907,China)。
文摘Existing traditional Chinese medicine(TCM)-related databases are still insufficient in data standardization,integrity and precision,and need to be updated urgently.Herein,an Encyclopedia of Traditional Chinese Medicine version 2.0(ETCM v2.0,http://www.tcmip.cn/ETCM2/front/#/)was constructed as the latest curated database hosting 48,442 TCM formulas recorded by ancient Chinese medical books,9872 Chinese patent drugs,2079 Chinese medicinal materials and 38,298 ingredients.To facilitate the mechanistic research and new drug discovery,we improved the target identification method based on a two-dimensional ligand similarity search module,which provides the confirmed and/or potential targets of each ingredient,as well as their binding activities.Importantly,five TCM formulas/Chinese patent drugs/herbs/ingredients with the highest Jaccard similarity scores to the submitted drugs are offered in ETCM v2.0,which may be of significance to identify prescriptions/herbs/ingredients with similar clinical efficacy,to summarize the rules of prescription use,and to find alternative drugs for endangered Chinese medicinal materials.Moreover,ETCM v2.0 provides an enhanced Java Script-based network visualization tool for creating,modifying and exploring multi-scale biological networks.ETCM v2.0 may be a major data warehouse for the quality marker identification of TCMs,the TCM-derived drug discovery and repurposing,and the pharmacological mechanism investigation of TCMs against various human diseases.
文摘A brief survey and prospect on the research of the quality of traditional Chinese medicinal materials by means of plant ecology is given in this paper. It is concluded that the new methods and accomplish ment in plant ecology,combined with other related subjects,should be used fully in this research.Such combination might result in some new disciphines.
