Near Infrared spectroscopy(NIRS)has been widely used in the discrimination(classification)of pharmaceutical drugs.In real applications,however,the class imbalance of the drug samples,i.e.,the number of one drug sample...Near Infrared spectroscopy(NIRS)has been widely used in the discrimination(classification)of pharmaceutical drugs.In real applications,however,the class imbalance of the drug samples,i.e.,the number of one drug sample may be much larger than the number of the other drugs,deceasesdrastically the discrimination performance of the classification models.To address this classimbalance problem,a new computational method--the scaled convex hull(SCH)-basedmaximum margin classifier is proposed in this paper.By a suitable selection of the reductionfactor of the SCHs generated by the two classes of drug samples,respectively,the maximalmargin classifier bet ween SCHs can be constructed which can obtain good classification per-formance.With an optimization of the parameters involved in the modeling by Cuckoo Search,a satisfied model is achieved for the classification of the drug.The experiments on spectra samplesproduced by a pharmaceutical company show that the proposed method is more effective androbust than the existing ones.展开更多
基金funded by the National Nat ural Science Foundation of China(Grant Nos.61105004,61071136and 21365008)Natural Science Foundation of Guangxi(Grant No.2013GXNSFBA019279)Innovation Project of GUET Graduate Education(No.ZYC0725).
文摘Near Infrared spectroscopy(NIRS)has been widely used in the discrimination(classification)of pharmaceutical drugs.In real applications,however,the class imbalance of the drug samples,i.e.,the number of one drug sample may be much larger than the number of the other drugs,deceasesdrastically the discrimination performance of the classification models.To address this classimbalance problem,a new computational method--the scaled convex hull(SCH)-basedmaximum margin classifier is proposed in this paper.By a suitable selection of the reductionfactor of the SCHs generated by the two classes of drug samples,respectively,the maximalmargin classifier bet ween SCHs can be constructed which can obtain good classification per-formance.With an optimization of the parameters involved in the modeling by Cuckoo Search,a satisfied model is achieved for the classification of the drug.The experiments on spectra samplesproduced by a pharmaceutical company show that the proposed method is more effective androbust than the existing ones.
