Objective： To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals....Objective： To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals. Methods： In this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin （1 g/day） or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory （BAI） and Beck Depression Inventory （BDI） scales, respectively. Results： Mean BAI score was found to be significantly reduced following curcumin therapy （P=0.03）. However, curcumin supplementation did not exert any significant impact on BDI scores （P=0.7）. Conclusion： Curcumin has a potential anti-anxiety effect in individuals with obesity.展开更多
In isotope 137 Cs tracing studies, it is a premise to determine suitable 137 Cs reference inventory（CRI） plots and the CRI values. Owing to the heterogeneous spatial distribution of 137 Cs deposition in the ground a...In isotope 137 Cs tracing studies, it is a premise to determine suitable 137 Cs reference inventory（CRI） plots and the CRI values. Owing to the heterogeneous spatial distribution of 137 Cs deposition in the ground and diverse, or even irregular, operations in sampling and testing procedures, CRI determination is usually faced with many difficulties and uncertainties. In addition, more difficulties occur in an investigation of a large-scale region because of time constraints and measurement cost limitations. In this study, traditional CRI acquiring methods were summarized first, and then a new complex scheme was established, involving seven core steps and coupling the model estimate and sample measurement. The above CRI determination methodology was implemented in the central-eastern Inner Mongolia Plateau. The case study results showed that the CRI in the dark chestnut soil sub-region, located in the east and south of Xing＇an City, exhibited 2447 Bq·m–2; the CRI in the aeolian sandy soil sub-region, positioned in the south central Tongliao City and central Chifeng City, showed 2430 Bq·m–2; the CRI in the sandy chernozem soil sub-region, situated in the northwestern Chifeng City, presented 2384 Bq·m–2; and the CRI in the chestnut soil sub-region, in the southern Xilin Gol City, was 2368 Bq·m–2. The newly proposed CRI determination scheme was proved effective, and the determined CRI plots and CRI values were convincing. The methodology offered a framework for 137 Cs tracing studies in large-scale regions or long-distance transects.展开更多
基金Support by the Research Council at the Mashhad University of Medical Sciences,Mashhad,Iran
文摘Objective： To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals. Methods： In this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin （1 g/day） or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory （BAI） and Beck Depression Inventory （BDI） scales, respectively. Results： Mean BAI score was found to be significantly reduced following curcumin therapy （P=0.03）. However, curcumin supplementation did not exert any significant impact on BDI scores （P=0.7）. Conclusion： Curcumin has a potential anti-anxiety effect in individuals with obesity.
基金National Key Basic Research Program of China（973 Program）,No.2010CB950904 National Natural Science Foundation of China,No.40971223 Knowledge Innovation Project of CAS,No.KZCX2-EW-306
文摘In isotope 137 Cs tracing studies, it is a premise to determine suitable 137 Cs reference inventory（CRI） plots and the CRI values. Owing to the heterogeneous spatial distribution of 137 Cs deposition in the ground and diverse, or even irregular, operations in sampling and testing procedures, CRI determination is usually faced with many difficulties and uncertainties. In addition, more difficulties occur in an investigation of a large-scale region because of time constraints and measurement cost limitations. In this study, traditional CRI acquiring methods were summarized first, and then a new complex scheme was established, involving seven core steps and coupling the model estimate and sample measurement. The above CRI determination methodology was implemented in the central-eastern Inner Mongolia Plateau. The case study results showed that the CRI in the dark chestnut soil sub-region, located in the east and south of Xing＇an City, exhibited 2447 Bq·m–2; the CRI in the aeolian sandy soil sub-region, positioned in the south central Tongliao City and central Chifeng City, showed 2430 Bq·m–2; the CRI in the sandy chernozem soil sub-region, situated in the northwestern Chifeng City, presented 2384 Bq·m–2; and the CRI in the chestnut soil sub-region, in the southern Xilin Gol City, was 2368 Bq·m–2. The newly proposed CRI determination scheme was proved effective, and the determined CRI plots and CRI values were convincing. The methodology offered a framework for 137 Cs tracing studies in large-scale regions or long-distance transects.
