The human scalp harbors a diverse range of microbiome,much like other skin surfaces,where both beneficial and harmful microorganisms coexist.This study explores the possibility of balancing key scalp microorganisms,pa...The human scalp harbors a diverse range of microbiome,much like other skin surfaces,where both beneficial and harmful microorganisms coexist.This study explores the possibility of balancing key scalp microorganisms,particularly Staphylococcus epidermidis,Staphylococcus aureus and Malassezia species.While Staphylococcus epidermidis plays a beneficial role in maintaining scalp health by producing antimicrobial proteins and supporting the skin barrier,Staphylococcus aureus is identified as a pathogen linked to skin infections and dandruff formation.Malassezia fungi degrade triglycerides in sebum into unsaturated fatty acids,exacerbating scalp conditions like dandruff.In order to promote the beneficial microbe while inhibit the harmful ones,we investigated the combination of 1.0 mM pyrrolidone carboxylate-zinc(PCA-Zn),0.2%malt oligosaccharides(MT:corn-derived oligosaccharide mainly containing maltotetraose)and 0.05 mM Hinokitiol on its microbial activity,which significantly enhanced the growth of Staphylococcus epidermidis while inhibiting both Staphylococcus aureus and Malassezia,offering insights into promising strategies for scalp care.展开更多
文摘The human scalp harbors a diverse range of microbiome,much like other skin surfaces,where both beneficial and harmful microorganisms coexist.This study explores the possibility of balancing key scalp microorganisms,particularly Staphylococcus epidermidis,Staphylococcus aureus and Malassezia species.While Staphylococcus epidermidis plays a beneficial role in maintaining scalp health by producing antimicrobial proteins and supporting the skin barrier,Staphylococcus aureus is identified as a pathogen linked to skin infections and dandruff formation.Malassezia fungi degrade triglycerides in sebum into unsaturated fatty acids,exacerbating scalp conditions like dandruff.In order to promote the beneficial microbe while inhibit the harmful ones,we investigated the combination of 1.0 mM pyrrolidone carboxylate-zinc(PCA-Zn),0.2%malt oligosaccharides(MT:corn-derived oligosaccharide mainly containing maltotetraose)and 0.05 mM Hinokitiol on its microbial activity,which significantly enhanced the growth of Staphylococcus epidermidis while inhibiting both Staphylococcus aureus and Malassezia,offering insights into promising strategies for scalp care.
