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Vaginal Cesarean Section, an Alternative to High-Risk Trigger on Scarred Uterus
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作者 Famakan Kane Mahamadou Keita +3 位作者 Yacouba Sylla Soumaila Diallo Diassana Mahamadou Traore Tidiane 《Open Journal of Obstetrics and Gynecology》 2024年第7期979-982,共4页
The objective is to report a clinical case of vaginal cesarean section performed to expel a dead fetus in scarred uterus. For this indication, vaginal hysterectomy constitutes an alternative to vaginal expulsion with ... The objective is to report a clinical case of vaginal cesarean section performed to expel a dead fetus in scarred uterus. For this indication, vaginal hysterectomy constitutes an alternative to vaginal expulsion with a high risk of uterine rupture and to classic abdominal cesarean section with risk of significant surgical trauma, particularly adhesions. However, this surgical technique, described since the 19th century, remains unknown to many practitioners and few publications exist on the subject throughout the world. Considered obsolete by some practitioners, it retains all its advantages in the practice of modern obstetrics. We report this case of expulsion of fetal death on a tri-scarred uterus performed by vaginal cesarean section at the Health District Reference Health Center (District Hospital) of Commune I in Bamako, Mali in a 37-year-old patient with a pregnancy of 27 weeks of amenorrhea. 展开更多
关键词 Vaginal Cesarean Section Birth on scarred uterus In Utero Fetal Death
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Predictive Factors of Complications of Vaginal Delivery on Scarred Uterus at the YaoundéGynaeco-Obstetric and Paediatric Hospital 被引量:1
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作者 E. Ngo Um Meka P. Foumane +3 位作者 F. Essiben E. R. Ngwesse J. Dohbit Sama E. T. Mboudou 《Open Journal of Obstetrics and Gynecology》 2016年第13期851-860,共10页
Objective: This study was aimed at identifying predictive factors of complications during vaginal delivery on scarred uterus. Methodology: During 9 months, from October 1st, 2015 to June 30th, 2016, a case control stu... Objective: This study was aimed at identifying predictive factors of complications during vaginal delivery on scarred uterus. Methodology: During 9 months, from October 1st, 2015 to June 30th, 2016, a case control study was carried out at the Yaoundé Gynaeco-Obstetric and Pediatric Hospital. Eighty nine women each with a single scarred uterus who presented with complications during delivery (cases) were compared to eighty nine others who had a successfully trial of scar (control) during the study period. Data were analyzed using the CSPro version 6.0 and SPSS version 20.0 softwares with statistical significance set at P Results: We recruited 2 groups of 89 women, aged 17 to 40 years, with an average age of 29.05 years. The majority of women with complications were married (50.6%) and unemployed (42.8%). Following univariate analysis, predictive factors of complications were: prematurity (OR = 7.4), post-term (OR = 13.7), no history of vaginal delivery on scarred uterus (OR = 4.3), inter-pregnancy spacing period greater than 60 months (five years) (OR = 2.9), History of caesarian delivery indicated for cephalo-pelvic disproportion (OR = 6.6), less than four ante-natal consultations (OR = 3.6), antenatal consultations done in a Health Centre (OR = 2.7), ante-natal follow up conducted by a nurse (OR = 2.4;IC = [1.2 - 4.7]), referral from a different health unit (OR = 4.4, IC = 2.0 - 9.4), a Bishop score less than 7 on admission (OR = 12.4, IC = 5.6 - 27.4), a meconium stained amniotic fluid (OR = 9.9;CI = [3.6 - 26.8]). After logistic regression, the retained factors associated with complications were post-term (aOR = 34.5), absence of vaginal birth after caesarian delivery, (aOR = 11.7), previous caesarean section indicated for cephalo-pelvic disproportion (aOR = 6.1), a bishop score less than 7 (aOR = 12.0), meconium stained amniotic fluid (aOR = 13.6). Conclusion: Predictive factors of complications can help anticipate negative obstetric outcomes. 展开更多
关键词 CAESAREAN scarred uterus Obstetrical Complications Predictive Factors
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Placenta Percreta Causing Rupture of Uterus in Second Trimester of Pregnancy in Non Scarred Uterus with an Unusual Presentation: A Case Report and Review of Literature
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作者 Reena Pal Deepmala Prasad Suchitra Jain 《Open Journal of Obstetrics and Gynecology》 2014年第11期695-698,共4页
Placenta percreta causing second trimester, spontaneous uterine rupture in non high risk women is less frequent and fewer cases have been reported in the literature. We report a case of uterine rupture in second trime... Placenta percreta causing second trimester, spontaneous uterine rupture in non high risk women is less frequent and fewer cases have been reported in the literature. We report a case of uterine rupture in second trimester of pregnancy due to placenta percreta with non specific symptoms in otherwise uncomplicated pregnancy without any high risk factors. This case report describes the case of young woman presenting second gravid with 21 weeks pregnancy with complaints of whole abdomen pain and dysuria. Ultrasonography shows single intrauterine dead fetus;placenta was fundoposterior in upper segment, a hypoechoic area seen below the placenta suggestive of abruption placentae or placenta accreta. Suddenly patient deteriorated in two hours of hospital stay, frank hemoperitoneum detected, emergency laparotomy done, per operatively whole fundal area of uterus became papery thin and cystic on touch, a small rent seen on fundal surface of uterus. The placenta was densely adhered to the fundoposterior aspect of the uterus. Patient had emergency subtotal hysterectomy. This case highlights that placenta percreta is a rare but serious complication of pregnancy which may present in early pregnancy without any associated high risk factors for placenta percreta with unusual symptoms. 展开更多
关键词 PLACENTA Percreta SPONTANEOUS UTERINE RUPTURE Second Trimester Non scarred uterus
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Delivery on Scarred Uterus at Souro Sanou Teaching Hospital, Burkina Faso (about 531 Cases)
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作者 Yaméogo Rélwendé Barnabé Kaboré Ahmed +2 位作者 Komboigo Béwendin Evélyne Somé Der Adolphe Bambara Moussa 《Open Journal of Obstetrics and Gynecology》 CAS 2022年第9期927-933,共7页
Introduction: Therapeutic conduct for delivery via a scarred uterus is controversial in modern obstetrics. Some authors recommend a ceasarean section. The purpose of this study was to analyse the conduct and prognosis... Introduction: Therapeutic conduct for delivery via a scarred uterus is controversial in modern obstetrics. Some authors recommend a ceasarean section. The purpose of this study was to analyse the conduct and prognosis of delivery via scarred uterus at Souro Sanou Teaching Hospital in Bobo-Dioulasso. Methods: We conducted a descriptive cross-sectional study from January 1 to December 31, 2017. Data were collected from medical, birth, and operating room records. Result: In total, 531 scared uterus deliveries and 5293 deliveries have been recorded in our study;the frequency of deliveries via a scarred uterus was 9.96%. The average age of the patients was 28.02 years old, with extremes of 17 and 44 years. The average parity was 2.34, with extremes of 1 and 8. Patients with a spacing interval between births of at least 24 months accounted for 86.6% of observed patients. Patients with a single scar uterus made up 70.6% of the population. There were 349 (65.73%) patients who had an emergency caesarean section during a previous delivery. The trial of vaginal delivery via a scarred uterus was conducted on 182 patients with a success rate of 89.56%. There was no maternal death. However, we noted 23 foetal deaths (4.33%). Conclusion: More than 50% of parturient women with a single caesarean uterine scar who underwent the uterine test gave birth vaginally in our department. However, like most previous studies on the subject, we recommend vaginal delivery in the presence of a prior caesarean-scarred uterus whenever possible. 展开更多
关键词 scarred uterus Delivery Bobo Dioulasso
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Emergency C-Section on Multi-Scar Uterus: Maternal and Fetal Prognosis at the Nianankoro Fomba Hospital in Segou, Mali
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作者 Tidiani Traoré Seydou Traoré +21 位作者 Seydou Z. Dao Abdoul K. Ballo Kassoum Sidibé Brahima Donigolo Babou Traoré Famakan Kané Adama Coulibaly Abdrahamane Diarisso Alima Sidibé Adama Camara Yacouba Dembélé Thierno Boubacar Bagayoko Alpha Sanogo Adama Bah Abdoulaye Kassogue Hamidou Toungara Seydina Alioun Beye Agoustin Thera Youssou Traoré Ibrahima Teguété Niani Mounkoro Amadou Dolo 《Open Journal of Obstetrics and Gynecology》 CAS 2023年第5期997-1005,共9页
Background: Multi-scar uterus is a uterus with two or more scars due to surgery or trauma. Objective: The aim was to compare the maternal and fetal prognosis of emergency C-sections of bi-scar uteruses to those of ute... Background: Multi-scar uterus is a uterus with two or more scars due to surgery or trauma. Objective: The aim was to compare the maternal and fetal prognosis of emergency C-sections of bi-scar uteruses to those of uteruses with at least 3 scars at the Nianankoro Fomba Hospital in Segou. Materials and Methods: It was a descriptive and analytical cross-sectional study with prospective data collection over a 24-month period from March 20, 2018, to March 20, 2020. Results: In 2 years, we collected 103 emergency C-sections for multi-scar uterus out of 1198 C-sections with a frequency of 8.6%. The age group of 20 to 35 years was the most represented with 86.4%. The bi-scar uteruses were the most frequent with 77.7%. In 71.8% of cases, the C-section was performed during the latent phase of labor. The C-section was performed under loco-regional anesthesia in 89.3% of cases. Difficulties in hemostasis and bladder injury were the most frequent intraoperative accidents. Surgical site infection was the main postoperative complication. No maternal deaths were recorded. The perinatal prognosis was marked by 4.3% fresh stillbirths in bi-scar uterus against 3.7% in three or more scar uteruses and including 2 fresh stillbirths and 1 macerated. We did not record any early neonatal deaths after C-section. Conclusion: The frequency of emergency C-sections in patients with a multi-scar uterus remains very high in our hospital. A better awareness of the patients, their spouses and all the actors involved in the management of pregnancies and childbirth, can contribute to curb this trend. 展开更多
关键词 C-Section PROGNOSIS Segou Multi-scar uterus EMERGENCY
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The Birth on a Scarred Uterus at the Reference Health Center (csref) of Kolondiéba: Socio-Epidemiological and Maternel-Fetal Prognosis Aspect
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作者 Siaka Konaté Kélétigui Samuel Dembélé +6 位作者 Moussa Samaké Yacouba Dembélé Magacha Goita Mamoutou Diarra Souleymane Benké Dembélé Bakary Tientigui Dembélé Adégné Pierre Togo 《Surgical Science》 2025年第1期26-33,共8页
Introduction: Childbirth on a scarred uterus is a major issue for health centers, especially peripheral, due to the major obstetric risks it presents. The objectives were to evaluate the frequency, route of delivery a... Introduction: Childbirth on a scarred uterus is a major issue for health centers, especially peripheral, due to the major obstetric risks it presents. The objectives were to evaluate the frequency, route of delivery and maternal-fetal prognosis of this type of delivery at csref of Kolondiéba. Materials and Methods: This was a retrospective cross-sectional study for one year (1 January 2023-31 December 2023). All patients admitted to the maternity ward of the center with at least one uterine scar and treated in the center were included. We extracted data from partograms, OR records, birth records and obstetric records. Input was done on Excel 2010 and analysis on SPSS.23. Results: The frequency of scarring uterus was 16.8% (217/1285 births). The average age was 27. Pauciparous were most represented (59%). Patients were received from community health centers (44.7%). Prenatal consultation sessions (1 - 3 sessions) were performed at (64.9%). Uterine scars were obstetric in (99%). The cesarean section was performed immediately in (59.4%), it was prophylactic in 17%. The uterine test was attempted in (25.34%) with (69%) success. We recorded 3.6% uterine ruptures, 8.7% postoperative complications, 5.5% stillbirths and one maternal death (0.46%). Conclusion: Births on a scarred uterus are frequent and associated with a high rate of complications. 展开更多
关键词 uterus scar Delivery Kolondiéba Reference Health Center
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瘢痕子宫阴道试产的影响因素
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作者 林华兰 蓝柳冰 《中外医学研究》 2025年第1期171-173,共3页
我国剖宫产率一直居高不下,而剖宫产率上升导致瘢痕子宫(scar uterus,SU)增加。随着国家生育政策的开放,剖宫产后再次妊娠分娩方式的选择成为产科医生面临的比较重要的问题,孕产妇可选择剖宫产后阴道试产(trial of labor after cesarean... 我国剖宫产率一直居高不下,而剖宫产率上升导致瘢痕子宫(scar uterus,SU)增加。随着国家生育政策的开放,剖宫产后再次妊娠分娩方式的选择成为产科医生面临的比较重要的问题,孕产妇可选择剖宫产后阴道试产(trial of labor after cesarean,TOLAC),或选择性再次剖宫产(elective repeat cesarean section,ERCS)。相对TOLAC,ERCS并发症较多,如子宫二次损伤、瘢痕憩室、子宫瘢痕部位妊娠等,而阴道分娩可以减少这些并发症的发生。但SU阴道分娩成功与否受到很多因素的影响,对既往有SU的孕产妇就分娩方式的风险和益处进行仔细和周到的咨询是谨慎的,关于SU妊娠女性的分娩管理仍然存在争议。本文通过从SU阴道分娩影响因素角度分析,为日后SU阴道分娩提供参考,提高母婴保障。 展开更多
关键词 剖宫产 瘢痕子宫 阴道试产 影响因素
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瘢痕子宫再次妊娠孕妇孕晚期抑郁发生情况及影响因素
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作者 肖新燕 李燕敏 朱立华 《中国计划生育学杂志》 2024年第7期1483-1487,共5页
目的:调查瘢痕子宫(SU)再次妊娠孕妇孕晚期抑郁发生情况并分析影响因素。方法:选择2021年1月-2023年12月在本院产前检测的278例SU再次妊娠孕妇,均于孕晚期采用健康问卷(PHQ-9)评定,根据评估结果分成抑郁组和无抑郁组。收集两组17项资料... 目的:调查瘢痕子宫(SU)再次妊娠孕妇孕晚期抑郁发生情况并分析影响因素。方法:选择2021年1月-2023年12月在本院产前检测的278例SU再次妊娠孕妇,均于孕晚期采用健康问卷(PHQ-9)评定,根据评估结果分成抑郁组和无抑郁组。收集两组17项资料并开展比较,通过多因素分析筛查SU再次妊娠孕妇孕晚期抑郁发生的影响因素。结果:22.3%(62/278)的SU再次妊娠孕妇孕晚期发生抑郁;抑郁组和无抑郁组学历、不良妊娠经历、睡眠状况、妊娠并发症、性格内向、家庭关怀度、近期出现负性生活事件等均有差异(P<0.05);SU再次妊娠孕妇孕晚期抑郁发生的危险因素主要包括有不良妊娠经历(OR=2.816,95%CI 1.570~5.050)、睡眠状况差(OR=2.514,95%CI 1.377~4.589)、性格内向(OR=2.408,95%CI 1.289~4.500)、家庭关怀度差(OR=3.022,95%CI 1.708~5.316)、近期出现负性生活事件(OR=2.862,95%CI 1.577~5.193)。结论:不良妊娠经历、睡眠状况差、性格内向、家庭关怀度差、近期出现负性生活事件与SU再次妊娠孕妇孕晚期抑郁发生有关。提示临床应针对上述情况施以孕妇针对性教育、心理支持及健康行为干预,以预防抑郁发生。 展开更多
关键词 瘢痕子宫 再次妊娠 孕晚期 抑郁 影响因素
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剖宫产术后瘢痕子宫再次妊娠行阴道试产的临床可行性分析
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作者 赵飞 宁方娇 李宁 《中国现代药物应用》 2024年第17期46-49,共4页
目的 研究剖宫产术后瘢痕子宫再次妊娠行阴道试产的临床可行性。方法 选择剖宫产术后再次妊娠行阴道试产的66例产妇作为瘢痕组,另选择同期非瘢痕子宫妊娠行阴道试产的66例产妇作为非瘢痕组。比较两组阴道试产结果,阴道试产成功产妇产程... 目的 研究剖宫产术后瘢痕子宫再次妊娠行阴道试产的临床可行性。方法 选择剖宫产术后再次妊娠行阴道试产的66例产妇作为瘢痕组,另选择同期非瘢痕子宫妊娠行阴道试产的66例产妇作为非瘢痕组。比较两组阴道试产结果,阴道试产成功产妇产程,产后出血量、住院时间及产后胎盘残留发生情况,不良妊娠结局发生情况,新生儿Apgar评分。结果 瘢痕组与非瘢痕组的阴道试产成功率(78.79%VS 84.85%)、转剖宫产率(21.21%VS 15.15%)比较,差异无统计学意义(P>0.05)。瘢痕组阴道试产成功产妇第一、二、三产程及总产程时间与非瘢痕组比较,差异无统计学意义(P>0.05)。瘢痕组产后出血量(210.28±56.36)ml、住院时间(3.69±1.62)d和产后胎盘残留发生率12.12%与非瘢痕组的(205.17±49.69)ml、(3.71±1.59)d、7.58%(5/66)比较,差异无统计学意义(P>0.05)。瘢痕组不良妊娠结局发生率(13.64%)与非瘢痕组(10.61%)比较,差异无统计学意义(P>0.05)。瘢痕组出生后1、5、10 min的新生儿Apgar评分比较,差异无统计学意义(P>0.05)。两组新生儿预后良好,无转入新生儿科记录。结论 剖宫产术后瘢痕子宫再次妊娠产妇的阴道试产成功率与非瘢痕子宫妊娠产妇基本一致,且未增加产程时间及产后出血量,不良妊娠结局发生率无明显升高,临床应用安全性可靠,证实该类产妇经阴道分娩的可行性较强,对提升阴道分娩率及降低剖宫产率具有重要应用价值。 展开更多
关键词 剖宫产 瘢痕子宫 阴道试产 再次妊娠 产后出血 不良妊娠结局
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影响瘢痕子宫再妊娠并发凶险性前置胎盘的因素及妊娠结局分析
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作者 罗晓芳 王昊 邹虹 《中国现代医学杂志》 CAS 2024年第23期68-73,共6页
目的分析影响瘢痕子宫再妊娠并发凶险性前置胎盘的因素及妊娠结局。方法回顾性分析2019年10月—2020年10月重庆医科大学附属第一医院、重庆医科大学附属妇女儿童医院、重庆医科大学附属大学城医院住院分娩并发前置胎盘的200例二次剖宫... 目的分析影响瘢痕子宫再妊娠并发凶险性前置胎盘的因素及妊娠结局。方法回顾性分析2019年10月—2020年10月重庆医科大学附属第一医院、重庆医科大学附属妇女儿童医院、重庆医科大学附属大学城医院住院分娩并发前置胎盘的200例二次剖宫产单胎妊娠产妇的分娩数据,按是否并发凶险性前置胎盘将产妇分为非凶险性前置胎盘组(122例)与凶险性前置胎盘组(78例),对两组产妇本次及前次的剖宫产基本情况、术中和术后情况、新生儿结局进行比较,并通过构建多因素逐步Logistic回归模型分析瘢痕子宫再妊娠并发凶险性前置胎盘的危险因素。结果非凶险性前置胎盘组产妇前次剖宫产时发生的急诊剖宫产占比高于凶险性前置胎盘组产妇(P<0.05);非凶险性前置胎盘组产妇本次剖宫产时的妊娠次数、宫腔操作次数、宫腔操作≥3次、产前出血、24 h出血量、输血、产后出血、胎盘植入、弥散性血管内凝血、子宫切除、早产、新生儿重症监护病房入住,新生儿窒息均低于凶险性前置胎盘组产妇(P<0.05),新生儿出生体重大于凶险性前置胎盘组(P<0.05)。阴道试产失败行剖宫产产妇再妊娠并发凶险性前置胎盘的比例低于前次择期剖宫产产妇(P<0.05)。多因素逐步Logistic回归分析结果显示,宫腔操作次数多[OR=1.446(95%CI:1.132,1.851)]、前次择期剖宫产[OR=4.481(95%CI:1.758,11.412)]是瘢痕子宫再妊娠并发凶险性前置胎盘的危险因素(P<0.05)。结论既往宫腔操作次多以及前次择期剖宫产是瘢痕子宫再妊娠并发凶险性前置胎盘的危险因素。 展开更多
关键词 瘢痕子宫 前置胎盘 择期剖宫产 危险因素
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卡前列素氨丁三醇注射液不同时机给药对瘢痕子宫患者再次剖宫产术后出血的预防效果
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作者 陈玲 曾翠英 《当代医学》 2024年第12期40-44,共5页
目的探究卡前列素氨丁三醇注射液不同时机给药对瘢痕子宫患者再次剖宫产术后出血的预防效果。方法选取2019年1月至2022年5月丰城市人民医院收治的80例瘢痕子宫再次剖宫产患者作为研究对象,采用随机数字表法分为A组与B组,每组40例。A组... 目的探究卡前列素氨丁三醇注射液不同时机给药对瘢痕子宫患者再次剖宫产术后出血的预防效果。方法选取2019年1月至2022年5月丰城市人民医院收治的80例瘢痕子宫再次剖宫产患者作为研究对象,采用随机数字表法分为A组与B组,每组40例。A组在宫缩乏力时给予卡前列素氨丁三醇注射液,B组在胎儿娩出后即刻给予卡前列素氨丁三醇注射液。比较两组产后出血量、血流动力学指标[心率(HR)、平均动脉压(MAP)]、凝血功能[D-二聚体(D-D)、纤溶酶-抗纤溶酶复合物(PAP)、凝血酶-抗凝血酶复合物(TAT)、纤维蛋白原(Fg)]、康复时间及不良反应发生情况。结果术中及术后2、24h,B组出血量均少于A组,差异有统计学意义(P<0.05)。术后24h时,B组HR水平低于A组,MAP水平高于A组,差异有统计学意义(P<0.05)。术后24h时,B组D-D、PAP、Fg水平均低于A组,TAT水平高于A组,差异有统计学意义(P<0.05)。B组肛门排气时间、排便时间、下床时间、住院时间均短于A组,差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义。结论在瘢痕子宫患者再次剖宫产术胎儿娩出后即刻给予卡前列素氨丁三醇注射液,可减少产后出血量,缩短术后康复时间,且不增加不良反应发生,值得临床推广应用。 展开更多
关键词 瘢痕子宫 卡前列素氨丁三醇 给药时机
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多元共享决策模式对瘢痕子宫再次妊娠分娩方式的影响 被引量:3
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作者 周莉莉 翟巾帼 +2 位作者 陶杰 周丽花 刘轩田 《实用医学杂志》 CAS 北大核心 2024年第4期561-565,共5页
目的探究决策辅助手册联合在线分娩决策支持的多元共享决策模式对瘢痕子宫再次妊娠女性分娩方式的影响。方法选取2019年9月至2022年10月在某三甲医院产检的94例瘢痕子宫再次妊娠女性为研究对象,采用随机数字表法分为观察组与对照组。对... 目的探究决策辅助手册联合在线分娩决策支持的多元共享决策模式对瘢痕子宫再次妊娠女性分娩方式的影响。方法选取2019年9月至2022年10月在某三甲医院产检的94例瘢痕子宫再次妊娠女性为研究对象,采用随机数字表法分为观察组与对照组。对照组接受常规孕期宣教,观察组在常规孕期宣教的基础上接受多元共享决策干预。分别对两组分娩决策冲突程度、分娩方式偏好、分娩后决策后悔程度和最终分娩方式进行比较。结果观察组在接受多元共享决策干预后,决策冲突量表得分降低(P<0.001),在分娩方式偏好调查中表示“不确定”的人数减少,选择经阴道生产的人数增加;最终观察组孕妇行剖宫产者30人(68.2%),阴道分娩者14人(31.8%);观察组孕妇对本次分娩决策后悔程度低于对照组(P<0.001)。结论对瘢痕子宫再次妊娠女性开展多元共享决策可降低其决策冲突程度、增强阴道试产意愿并帮助其做出理性科学的分娩决策。 展开更多
关键词 瘢痕子宫 共享决策 决策辅助工具 选择性再次剖宫产 剖宫产术后再次妊娠阴道试产
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孕晚期血清血小板反应蛋白-1、D-二聚体及金属蛋白酶组织抑制物-1水平对瘢痕子宫再次妊娠患者产后出血的预测价值 被引量:1
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作者 李相杰 任艳芳 +2 位作者 王玉红 张全华 管文莉 《新乡医学院学报》 CAS 2024年第2期138-142,共5页
目的探讨孕晚期血清血小板反应蛋白-1(THBS-1)、D-二聚体(D-D)及金属蛋白酶组织抑制物-1(TIMP-1)水平对瘢痕子宫再次妊娠患者产后出血(PPH)的预测价值。方法选择2020年6月至2022年8月新乡医学院第一附属医院收治的108例瘢痕子宫再次妊... 目的探讨孕晚期血清血小板反应蛋白-1(THBS-1)、D-二聚体(D-D)及金属蛋白酶组织抑制物-1(TIMP-1)水平对瘢痕子宫再次妊娠患者产后出血(PPH)的预测价值。方法选择2020年6月至2022年8月新乡医学院第一附属医院收治的108例瘢痕子宫再次妊娠孕妇为研究对象,根据孕妇分娩后是否发生PPH分为PPH组(n=21)和非PPH组(n=87)。采集2组孕妇入院当天肘静脉血5 mL,应用酶联免疫吸附法检测2组孕妇血清THBS-1、D-D、TIMP-1水平。比较2组孕妇的基本临床资料及血清THBS-1、D-D、TIMP-1水平。采用多因素logistic回归分析瘢痕子宫再次妊娠孕妇发生PPH的影响因素,受试者操作特征(ROC)曲线分析血清THBS-1、D-D、TIMP-1水平对瘢痕子宫再次妊娠孕妇发生PPH的预测价值。结果PPH组人工流产次数≥2次、胎盘早剥、子宫切口撕裂、宫缩乏力、瘢痕厚度<0.3 cm占比及孕晚期血清THBS-1、D-D水平显著高于非PPH组,血清TIMP-1水平显著低于非PPH组(P<0.05)。宫缩乏力、D-D和THBS-1水平升高是瘢痕子宫再次妊娠孕妇PPH的独立危险因素(P<0.05),TIMP-1水平降低是瘢痕子宫再次妊娠孕妇PPH的保护因素(P<0.05)。血清THBS-1、D-D、TIMP-1联合预测瘢痕子宫再次妊娠孕妇PPH的曲线下面积大于三者单独预测(P<0.05)。结论孕晚期血清THBS-1、D-D、TIMP-1水平均可作为预测瘢痕子宫再次妊娠孕妇发生PPH的参考指标,且三者联合对瘢痕子宫再次妊娠孕妇发生PPH的预测效能更高。 展开更多
关键词 产后出血 血小板反应蛋白-1 D-二聚体 金属蛋白酶组织抑制物-1 瘢痕子宫
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43例子宫破裂的临床分析
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作者 林萍萍 樊佳宁 +3 位作者 陆倩倩 芮璨 栾婷 王新艳 《南京医科大学学报(自然科学版)》 CAS 北大核心 2024年第6期788-796,共9页
目的:探讨子宫破裂产妇的临床特点和妊娠结局。方法:回顾性分析2016年12月-2022年12月在南京医科大学附属妇产医院分娩的43例子宫破裂产妇的临床资料,按照是否有子宫手术史,分为瘢痕子宫组和非瘢痕子宫组,比较其临床特点和妊娠结局,并... 目的:探讨子宫破裂产妇的临床特点和妊娠结局。方法:回顾性分析2016年12月-2022年12月在南京医科大学附属妇产医院分娩的43例子宫破裂产妇的临床资料,按照是否有子宫手术史,分为瘢痕子宫组和非瘢痕子宫组,比较其临床特点和妊娠结局,并对20例经阴道试产发生子宫破裂产妇的产时情况进行分析。结果:43例子宫破裂产妇中瘢痕子宫33例,非瘢痕子宫10例;与瘢痕子宫组相比,非瘢痕子宫组术中出血量≥1000 mL的比例(P<0.001)、累积出血量≥1000 mL的比例(P=0.003)更高,输血率更高(P=0.012)。43例子宫破裂中预期剖宫产23例,余20例阴道试产者中产后发现子宫破裂组(13例)与产时发现子宫破裂组(7例)相比,产后发现子宫破裂组中完全性子宫破裂占比明显增加(P=0.044),输血率显著增加(P<0.001),两组相比差异有统计学意义。此外,与产后发现子宫破裂组相比,产时发现子宫破裂组中羊水异常比例和胎心改变比例增高,虽差异无统计学意义(P>0.05),但仍需引起临床高度重视。结论:非瘢痕子宫发生子宫破裂时出血量更多,阴道试产者于产后发现子宫破裂的并发症更严重,分娩前后应密切注意羊水、胎心、生命体征等情况,及时发现子宫破裂,降低母儿不良妊娠结局的发生率。 展开更多
关键词 子宫破裂 瘢痕子宫 非瘢痕子宫 阴道试产 剖宫产
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The Dose-response of Intrathecal Ropivacaine Co-administered with Sufentanil for Cesarean Delivery under Combined Spinal-epidural Anesthesia in Patients with Scarred Uterus 被引量:35
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作者 Fei Xiao Wen-Ping Xu +3 位作者 Yin-Fa Zhang Lin Liu Xia Liu Li-Zhong Wang 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第19期2577-2582,共6页
Background:Spinal anesthesia is considered as a reasonable anesthetic option in lower abdominal and lower limb surgery.This study was to determine the dose-response of intrathecal ropivacaine in patients with scarred... Background:Spinal anesthesia is considered as a reasonable anesthetic option in lower abdominal and lower limb surgery.This study was to determine the dose-response of intrathecal ropivacaine in patients with scarred uterus undergoing cesarean delivery under combined spinal-epidural anesthesia.Methods:Seventy-five patients with scarred uterus undergoing elective cesarean delivery under combined spinal-epidural anesthesia were enrolled in this randomized,double-blinded,dose-ranging study.Patients received 6,8,10,12,or 14 mg intrathecal hyperbaric ropivacaine with 5 μg sufentanil.Successful spinal anesthesia was defined as a T4 sensory level achieved with no need for epidural supplementation.The 50% effective dose (ED50) and 95% effective dose (ED95) were calculated with a logistic regression model.Results:ED50 and ED95 ofintrathecal hyperbaric ropivacaine for patients with scarred uterus undergoing cesarean delivery under combined spinal-epidural anesthesia (CSEA) were 8.28 mg (95% confidence interval [CI]:2.28-9.83 mg) and 12.24 mg (95% CI:10.53-21.88 mg),respectively.Conclusion:When a CSEA technique is to use in patients with scarred uterus for an elective cesarean delivery,the ED50 and ED95 of intrathecal hyperbaric ropivacaine along with 5 μg sufentanil were 8.28 mg and 12.24 mg,respectively.In addition,this local anesthetic is unsuitable for emergent cesarean delivery,but it has advantages for ambulatory patients. 展开更多
关键词 Cesarean Delivery DOSE-RESPONSE ROPIVACAINE scarred uterus SPINAL
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子宫下段前壁叠瓦式缝合术治疗瘢痕子宫合并前置胎盘伴胎盘植入产妇产后出血的临床效果
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作者 杨彩燕 谭芸 +2 位作者 杨钦灵 杨娟娟 覃钰芹 《临床医学研究与实践》 2024年第14期116-119,共4页
目的观察子宫下段前壁叠瓦式缝合术治疗瘢痕子宫合并前置胎盘伴胎盘植入产妇产后出血的临床效果。方法回顾性选取2020年1月至2023年1月诊断为瘢痕子宫合并前置胎盘伴胎盘植入的100例产妇,按照手术治疗方法将其分为试验组(50例,子宫下段... 目的观察子宫下段前壁叠瓦式缝合术治疗瘢痕子宫合并前置胎盘伴胎盘植入产妇产后出血的临床效果。方法回顾性选取2020年1月至2023年1月诊断为瘢痕子宫合并前置胎盘伴胎盘植入的100例产妇,按照手术治疗方法将其分为试验组(50例,子宫下段前壁叠瓦式缝合术)和对照组(50例,传统局部“8”字缝合术)。比较两组的止血效果、临床指标、血红蛋白水平及术后并发症发生情况。结果试验组的止血总有效率高于对照组,差异具有统计学意义(P<0.05)。试验组的手术时间短于对照组,红细胞输注量、血浆输注量、术后24 h总出血量、术中及术后缩宫素使用剂量、术中及术后欣母沛使用剂量少于对照组(P<0.05)。试验组的术后并发症总发生率明显低于对照组(P<0.05)。结论相较于传统局部“8”字缝合术,子宫下段前壁叠瓦式缝合术可为瘢痕子宫合并前置胎盘伴胎盘植入产妇产后出血的治疗提供一些新思路,是治疗此类患者的一种安全、有效的方法。 展开更多
关键词 叠瓦式缝合术 产后出血 瘢痕子宫 前置胎盘 胎盘植入
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艾司氯胺酮对妊娠期疤痕子宫肥胖孕妇剖宫产舒适度和产后抑郁的影响
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作者 许旭 陆璇 +2 位作者 吴浩 徐幻浠 李先蕊 《实用药物与临床》 CAS 2024年第12期904-908,共5页
目的 探讨艾司氯胺酮对妊娠期疤痕子宫肥胖孕妇剖宫产舒适度和产后抑郁的影响。方法 选择宿迁市第一人民医院2022年6月至2024年2月腰麻下剖宫产生育二孩或三孩的妊娠期疤痕子宫肥胖孕妇88例为研究对象,使用随机数字表法随机分为对照组(n... 目的 探讨艾司氯胺酮对妊娠期疤痕子宫肥胖孕妇剖宫产舒适度和产后抑郁的影响。方法 选择宿迁市第一人民医院2022年6月至2024年2月腰麻下剖宫产生育二孩或三孩的妊娠期疤痕子宫肥胖孕妇88例为研究对象,使用随机数字表法随机分为对照组(n=44)和观察组(n=44)。在切皮前和腹腔探查前,观察组均推注0.2 mg/kg的艾司氯胺酮,对照组推注等量生理盐水,对两组孕妇的牵拉反应评分、疼痛程度、抑郁状况、血清同型半胱氨酸(Hcy)及母婴不良反应进行比较。结果 在剖宫取胎和关腹前腹腔探查时,观察组的牵拉反应评分[(1.85±0.41)分和(2.17±0.53)分]明显低于对照组[(3.03±0.54)分和(3.78±0.64)分](P<0.05),观察组的疼痛评分明显低于对照组(P<0.05);观察组的恶心呕吐发生率(4.55%)明显低于对照组(20.45%)(P<0.05);在术后1 d、3 d和7 d时点,观察组的Hcy均显著低于对照组(P<0.05);在术后1 d、3 d和7 d时点,观察组的抑郁评分[(4.65±1.32)分、(4.14±1.16)分和(3.81±1.02)分]均显著低于对照组[(5.74±1.56)分、(5.25±1.35)分和(4.56±1.23)分](P<0.05)。结论 艾司氯胺酮能够显著缓解妊娠期疤痕子宫肥胖孕妇剖宫产时的牵拉反应和疼痛程度,有利于提高孕妇术中舒适度,并改善产后抑郁状况,且母婴不良反应少。 展开更多
关键词 艾司氯胺酮 妊娠期肥胖 疤痕子宫 舒适度 产后抑郁
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瘢痕子宫妊娠无症状型子宫破裂1例报告 被引量:1
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作者 顾莹琰 傅新露 卢丹 《实用临床医药杂志》 CAS 2024年第4期84-85,共2页
子宫破裂是一种严重的产科并发症,指在分娩期或妊娠期间,子宫体部或子宫下段发生破裂,导致母儿灾难性后果。本研究回顾性分析1例瘢痕子宫妊娠无症状型子宫破裂患者的临床资料,探讨瘢痕子宫妊娠的处理策略。
关键词 瘢痕子宫 无症状型子宫破裂 产科 妊娠
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卡孕栓联合缩宫素预防瘢痕子宫剖宫产产后出血的效果及对凝血指标的影响 被引量:2
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作者 梁静 谢佩真 《实用临床医学(江西)》 CAS 2024年第1期43-45,69,共4页
目的探讨卡孕栓联合缩宫素在预防瘢痕子宫剖宫产产后出血中的应用效果及其对凝血指标的影响。方法将94例行剖宫产手术的瘢痕子宫产妇随机分为观察组与对照组,每组47例。对照组在剖宫产产后采用缩宫素进行止血,观察组采用卡孕栓联合缩宫... 目的探讨卡孕栓联合缩宫素在预防瘢痕子宫剖宫产产后出血中的应用效果及其对凝血指标的影响。方法将94例行剖宫产手术的瘢痕子宫产妇随机分为观察组与对照组,每组47例。对照组在剖宫产产后采用缩宫素进行止血,观察组采用卡孕栓联合缩宫素进行止血。比较2组临床效果、产后出血量、凝血指标以及不良反应。结果与对照组相比,观察组总有效率显著升高,产后2、24 h出血量显著减少,活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)显著缩短,D-二聚体(D-D)、纤维蛋白原(FIB)水平显著升高,差异均有统计学意义(P<0.05);2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论卡孕栓联合缩宫素预防瘢痕子宫剖宫产产后出血效果显著,利于减少产妇产后出血量,改善产妇凝血功能,且安全性较高。 展开更多
关键词 瘢痕子宫 剖宫产 产后出血 卡孕栓 缩宫素 凝血指标
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卡前列素氨丁三醇联合缩宫素预防瘢痕子宫再次剖宫产产妇产后出血的价值 被引量:1
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作者 甘隆莺 《中外医学研究》 2024年第15期132-135,共4页
目的:分析卡前列素氨丁三醇联合缩宫素预防瘢痕子宫再次剖宫产产妇产后出血的价值。方法:选择2022年10月—2023年9月建瓯市妇幼保健院收治的60例瘢痕子宫再次剖宫产产妇作为研究对象,按随机数表法分为观察组和对照组,各30例。对照组给... 目的:分析卡前列素氨丁三醇联合缩宫素预防瘢痕子宫再次剖宫产产妇产后出血的价值。方法:选择2022年10月—2023年9月建瓯市妇幼保健院收治的60例瘢痕子宫再次剖宫产产妇作为研究对象,按随机数表法分为观察组和对照组,各30例。对照组给予缩宫素治疗,观察组在对照组基础上联合卡前列素氨丁三醇治疗。比较两组不同时间出血量、止血时间、子宫收缩持续情况、凝血功能指标及不良反应。结果:观察组术中及产后2 h、24 h出血量少于对照组,止血时间较对照组短,子宫收缩时间较对照组长,子宫底下降速度较对照组快,治疗后凝血酶原时间(PT)、凝活化部分凝血酶时间(APTT)短于对照组,纤维蛋白原(FIB)、D-二聚体(D-D)水平高于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:卡前列素丁三醇联合缩宫素预防瘢痕子宫再次剖宫产产妇产后出血效果良好,能减少产后出血量,缩短止血时间,改善凝血指标和子宫收缩情况,安全可靠。 展开更多
关键词 瘢痕子宫 剖宫产 卡前列素氨丁三醇 缩宫素 产后出血
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