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Global research trends and hotspots in overweight/obese comorbid with depression among children and adolescents: A bibliometric analysis
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作者 Ya-Qi Wang Tao-Tao Wu +2 位作者 Yan Li Shi-En Cui Ying-Shuai Li 《World Journal of Psychiatry》 SCIE 2024年第8期1267-1284,共18页
BACKGROUND Overweight/obesity combined with depression among children and adolescents(ODCA)is a global concern.The bidirectional relationship between depression and overweight/obesity often leads to their comorbidity.... BACKGROUND Overweight/obesity combined with depression among children and adolescents(ODCA)is a global concern.The bidirectional relationship between depression and overweight/obesity often leads to their comorbidity.Childhood and adolescence represent critical periods for physical and psychological development,during which the comorbidity of overweight/obesity and depression may increase the risk of adverse health outcomes.AIM To evaluate the relationship between ODCA,we conduct a bibliometric analysis to aid in formulating prevention and treatment strategies.METHODS From 2004 to 2023,articles related to ODCA were selected using the Science Citation Index Expanded from the Web of Science Core Collection.Bibliometric analysis of relevant publications,including countries/regions,institutions,authors,journals,references,and keywords,was conducted using the online bibliometric analysis platforms,CiteSpace,VOSviewer,and bibliometrix.RESULTS Between 2004 and 2023,a total of 1573 articles were published on ODCA.The United States has made leading contributions in this field,with Harvard University emerging as the leading contributor in terms of research output,and Tanofsky being the most prolific author.The J Adolescent Health has shown significant activity in this domain.Based on the results of the keyword and reference analyses,inequality,adverse childhood experiences,and comorbidities have become hot topics in ODCA.Moreover,the impact of balancedrelated behavior and exploration of the biological mechanisms,including the potential role of key adipocytokines and lipokines,as well as inflammation in ODCA,have emerged as frontier topics.CONCLUSION The trend of a significant increase in ODCA publications is expected to continue.The research findings will contribute to elucidating the pathogenic mechanisms of ODCA and its prevention and treatment. 展开更多
关键词 children Adolescents OVERWEIGHT OBESITY DEPRESSION Bibliometric analysis research trends
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Research Progress on the Pathogenesis of Primary Enuresis in Children
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作者 Yiyi Hou Lingling Zhang 《Expert Review of Chinese Medical》 2024年第1期1-5,共5页
Nocturnal enuresis(NE)is a common disease in children,commonly known as bedwetting.The International Children's Continence Society(ICCS)defines intermittent urinary incontinence during nighttime sleep in children ... Nocturnal enuresis(NE)is a common disease in children,commonly known as bedwetting.The International Children's Continence Society(ICCS)defines intermittent urinary incontinence during nighttime sleep in children aged 5 and above as enuresis.Enuresis can be divided into two types:primary nocturnal enuresis(PNE)and secondary nocturnal enuresis(SNE).PNE refers to nocturnal urinary control ability that has never been achieved for more than 6 months in children aged 5 and above with enuresis;SNE refers to the recurrence of enuresis symptoms after a period of more than 6 months of continuous nocturnal urinary control ability.SNE is relatively rare in clinical practice and is often caused by sudden stress events or other diseases such as snoring.Its pathogenesis and treatment are different from PNE.PNE is a multifactorial disease related to genetics,and its pathogenesis is not fully understood.There are not many research and review articles on its pathogenesis.In recent years,there has been significant progress in the epidemiology and pathogenesis of PNE.The following is a summary. 展开更多
关键词 children ENURESIS research progress
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Research Progress on Combined Chinese and Western Medicine Treatment of Mycoplasma pneumoniae Pneumonia in Children
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作者 Wenping Yang Le Wang +2 位作者 Sha Wang Nannan Ma Li Mei 《Journal of Clinical and Nursing Research》 2024年第6期117-122,共6页
With the continuous development of medical technology,combined treatment of Chinese and Western medicine has gradually become a research hotspot.As a common disease in pediatrics,the treatment of Mycoplasma pneumoniae... With the continuous development of medical technology,combined treatment of Chinese and Western medicine has gradually become a research hotspot.As a common disease in pediatrics,the treatment of Mycoplasma pneumoniae pneumonia(MPP)in children is also being explored and improved.This article summarizes the research progress of combined Chinese and Western medicine treatment of MPP in children in recent years,aiming to provide a useful reference for the combined treatment of MPP in children.The article firstly introduces the etiology and pathogenesis of MPP in children,thereafter briefly introduces the Western anti-infective treatment and traditional Chinese medicine(TCM)diagnosis and treatment of MPP in children,and lastly introduces the methods of combined treatment of TCM and Western medicine in detail.The article points out that the combination of Chinese and Western medicine can give full play to the overall regulation of Chinese medicine and the precise treatment advantages of Western medicine,improve the therapeutic effect,reduce the use of antibiotics,and lower the recurrence rate of the disease,which is worthy of further research and promotion. 展开更多
关键词 children Mycoplasma pneumoniae pneumonia Combined Chinese and Western medicine research progress
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Advances in the Study of Psychological Stress and Eating Behavior in Children and Adolescents
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作者 Ting He Le Wang +3 位作者 Sha Wang Nannan Ma Li Mei Mengdan Zheng 《Journal of Clinical and Nursing Research》 2024年第7期191-195,共5页
With the rapid development and change in society,children and adolescents are facing more and more psychological pressure,which comes not only from academic performance and interpersonal relationships but also from fa... With the rapid development and change in society,children and adolescents are facing more and more psychological pressure,which comes not only from academic performance and interpersonal relationships but also from family environment,social expectations and other aspects.Psychological stress not only affects the mental health of children and adolescents but is also closely related to their eating behavior.Therefore,exploring the relationship between psychological stress and eating behaviors is of great significance in promoting the physical and mental health development of children and adolescents.Based on this,the study reviewed the research progress on the relationship between psychological stress and eating behavior of children and adolescents in recent years.The relationships between psychological stress and general eating behaviors,abnormal eating behaviors and eating disorders were successively reviewed,and the related physiological mechanisms were explored with a view to providing a scientific basis for mental health education and eating behavior intervention for children and adolescents. 展开更多
关键词 children Adolescents Psychological stress Eating behavior research progress
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A Survey on English Reading Status of Left-behind Children in Rural Areas of Northern China
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作者 SUN Hong FAN Jun-nan +3 位作者 SHEN Yue-han ZHU Nan-nan XU Ning SHAO Ming-chong 《Journal of Literature and Art Studies》 2020年第11期1032-1035,共4页
Taking Suining County in Xuzhou city of Jiangsu province as the survey subject,this paper is to study the current English reading situation of the left-behind children based on a questionnaire survey of 472 respondent... Taking Suining County in Xuzhou city of Jiangsu province as the survey subject,this paper is to study the current English reading situation of the left-behind children based on a questionnaire survey of 472 respondents from 4 primary and middle schools in rural areas.The result indicated that there are serious problems in the current situation of English reading among left-behind children in rural areas,which are as follows:insufficient reading time and books,few access to having books,increased digital reading,many reading disabilities,poor reading environment,etc.This paper analyzes the reasons and gives corresponding countermeasures for society,school and family,to improve the English reading condition of rural left-behind children and to better promote their reading ability and habits.It also provides the reference for narrowing the disparity gap of reading resources services between urban and rural China. 展开更多
关键词 left-behind children in rural areas English reading analysis and research SOCIALIZATION
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Preschool Child's Researching Interests and Role of Visual Art's Expressing Media
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作者 Urgula Podobnik 《Sociology Study》 2014年第6期563-572,共10页
Genuine interest, research zeal, and visual art expressiveness which are typical of the pre-school period can pose a challenge to every teacher, at the same time, guide them when planning different contents for childr... Genuine interest, research zeal, and visual art expressiveness which are typical of the pre-school period can pose a challenge to every teacher, at the same time, guide them when planning different contents for children to explore and discover. As one of the primary expressing media and an important support when forming concepts, visual art plays an indispensable role in the pre-school period. The following thesis is based on an action research whose key tendencies were focused on establishing children's interests in different useful materials and tools while enabling them an autonomous visual art use of these tools and didactical possibilities of the teacher involved. The activities included in the research were fully in line with the Slovenian National Kindergarten Curriculum and the project was carried out in the form of several successive meetings intended for visual art creative activities. All activities in the research were photo-documented while the analysis of the research's data was performed based on observation and written notes referring to individual child's responses, his or her questions, ideas, and incentives, the course of cognitive and creative process, communication with the peers and teachers and other potential particularities. 展开更多
关键词 Preschool children researching interests visual art action research
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Lived experiences with unmet supportive care needs in pediatric cancer:Perspective of Chinese children and their parents 被引量:2
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作者 Lei Cheng Ling Yu +1 位作者 Haiying Huang Mingxia Duan 《International Journal of Nursing Sciences》 CSCD 2022年第4期430-437,共8页
Objective:Unmet supportive care needs(SCNs)impact pediatric cancer patients and their parents.This study aimed to explore the unmet SCNs from the perspective of Chinese children with cancer and their parents through l... Objective:Unmet supportive care needs(SCNs)impact pediatric cancer patients and their parents.This study aimed to explore the unmet SCNs from the perspective of Chinese children with cancer and their parents through lived experiences.Methods:The data of this study was collected using face-to-face semi-structured interviews.The participants were recruited from the oncology units of three children’s hospitals in China’s cities(Shanghai,Guangzhou,and Hefei)from October 2020 to December 2021.Data were analyzed using Colaizzi’s sevenstep phenomenological analysis method.Results:Eight pediatric cancer patients and twenty-four parents were enrolled in the study.Four main themes and eight subthemes(both children’s and parent’s perspectives)were generated:1)meeting the ongoing needs along the cancer trajectory(can you tell me what comes next;our needs are growing);2)communicating with a family focus(they only talk to my parents;let each family member have a voice);3)providing care beyond the treatment(I am bigger than my body[the children’s needs for emotional consolidation and information about their prognosis];there are things beyond treatment);4)getting support from the community(I am not a monster[the children were unhappy about being treated differently];we want to connect with the resources near us).Conclusion:This study revealed multiple unmet SCNs from the perspective of Chinese children with cancer and their parents.The findings call for comprehensive and in-depth supportive care beyond treatment,integration of the family member voice in pediatric cancer care,and a coordinated pediatric cancer support mechanism in the Chinese healthcare system. 展开更多
关键词 children China Health services needs and demand NEOPLASMS PARENTS Qualitative research
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Media as an Identity Negotiator Among "Swedish" Children in Athens and "Japanese" in London
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作者 Ulrika Sjoberg Kaoruko Kondo 《Journalism and Mass Communication》 2012年第1期250-262,共13页
With its transcultural perspective this paper looks at how families (i.e., parents and children) talk about children's identity and the importance of mothers' homeland media for the children, who are surrounded by... With its transcultural perspective this paper looks at how families (i.e., parents and children) talk about children's identity and the importance of mothers' homeland media for the children, who are surrounded by a global popular media culture. Both studies used similar methods: interviews, participant observation, and photo-taking. The analysis shows the complexity of identity formation and the need to apply a contextual and relational perspective when wanting to understand the roles of media in the process of forming identity. The mothers' homeland media is an important construction tool in the process and helps the children not only with languages but also catch up with information about peers in mothers' homeland. 展开更多
关键词 comparative research migration children IDENTITY homeland media use
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国外儿童正念研究热点与前沿的可视化分析 被引量:1
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作者 马颖 王珍真 白洁 《宁波教育学院学报》 2024年第1期59-64,共6页
为了解正念在儿童群体中的研究热点和前沿动态,研究者以ISI Web of Science数据库中2007—2021年的1900篇文献为原始数据,应用CiteSpace知识图谱软件,绘制与儿童正念研究相关的知识图谱,挖掘国外儿童正念的发表文献时间分布、研究热点... 为了解正念在儿童群体中的研究热点和前沿动态,研究者以ISI Web of Science数据库中2007—2021年的1900篇文献为原始数据,应用CiteSpace知识图谱软件,绘制与儿童正念研究相关的知识图谱,挖掘国外儿童正念的发表文献时间分布、研究热点与研究前沿。研究结果发现:国外儿童正念研究发文量近五年呈明显上升趋势,研究热点涉及正念疗法及其效果、儿童心理问题与行为问题、正念干预使用率、正念教养等领域,研究前沿主要包括正念干预的科学性、儿童社会情绪能力培养以及师生关系等研究主题。 展开更多
关键词 儿童 正念 CITESPACE 知识图谱 研究热点
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国际基于自我决定理论的儿童青少年体育活动研究现状与展望 被引量:1
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作者 尹雪娟 刘海元 黄先锋 《西安体育学院学报》 CSSCI 北大核心 2024年第1期37-51,共15页
为考察国际基于自我决定理论的儿童青少年体育活动研究的发展脉络和最新进展,运用科学计量学中的关键词共现、关键词聚类和可视化技术等方法对2000—2022年Web of Science核心合集数据库相关研究文献进行分析。结果发现:中国在亚洲国家... 为考察国际基于自我决定理论的儿童青少年体育活动研究的发展脉络和最新进展,运用科学计量学中的关键词共现、关键词聚类和可视化技术等方法对2000—2022年Web of Science核心合集数据库相关研究文献进行分析。结果发现:中国在亚洲国家中产出领先;历年研究呈现从宏观到微观、从单一到多重、从横断到纵横结合、从解决到预防、从验证到应用、从开拓到回顾的发展趋势,最新研究体现出重视结构化问卷、研究设计联系实际情境和纳入各种心理学变量的特点;已有研究存在针对特殊群体、干预的作用路径、系统化干预项目设计方法等方面的局限。对我国相关研究的启示:对热度仍持续的主题继续优化研究设计;对基本达到饱和的主题结合实际推进本土研究;利用多重变量关系路径、多元干预模型、跨情境研究、横向与纵向相结合等开展实证研究;编制、修订中国版的相关问卷。 展开更多
关键词 自我决定理论 儿童青少年 体育活动 研究主题 知识图谱
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The urban adaptation and adaptation process of urban migrant children: A qualitative study 被引量:2
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作者 LIU Yang FANG Xiaoyi +2 位作者 CAI Rong WU Yang ZHANG Yaofang 《Frontiers of Education in China》 2009年第3期365-389,共25页
This article employs qualitative research methods to explore the urban adaptation and adaptation processes of Chinese migrant children.Through twenty-one in-depth interviews with migrant children,the researchers disco... This article employs qualitative research methods to explore the urban adaptation and adaptation processes of Chinese migrant children.Through twenty-one in-depth interviews with migrant children,the researchers discovered:The participant migrant children showed a fairly high level of adaptation to the city;their process of urban adaptation emerged as three categories:the U-Type,the J-type,and the“flat line”type.Also explored were long-term acquisition of explicit behaviors,implicit notions,adaptation to the socio-cultural environment,and success in education as difficult aspects of adaptation.After comparing these three processes,the research team developed a theory of migrant children urban adaptation.It hypothesizes that during the urban adaptation process,migrant children will encounter four stages of development:excitement and curiosity,shock and resistance,exploration and adaptation,and finally integration and assimilation. 展开更多
关键词 migrant children urban adaptation urban adaptation development stages qualitative research
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儿童医院视角下药学人员科研指标评价体系的构建
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作者 高艳 李欣 +1 位作者 高翔 孙燕燕 《中国药房》 CAS 北大核心 2024年第18期2193-2198,共6页
目的构建适用于儿童医院药学人员的科研指标评价体系,为药学人员的科研能力评价提供技术支持和参考依据。方法运用文献/文本调研法,查找科研管理的相关文献、政策法规和研究报告;采用头脑风暴法梳理关键要素,逐级分解各级指标。在此基础... 目的构建适用于儿童医院药学人员的科研指标评价体系,为药学人员的科研能力评价提供技术支持和参考依据。方法运用文献/文本调研法,查找科研管理的相关文献、政策法规和研究报告;采用头脑风暴法梳理关键要素,逐级分解各级指标。在此基础上,使用专家访谈法,明确关键要素,初步拟定三级指标评价体系,并据此制作函询问卷。最后运用德尔菲法,通过3项筛选标准[重要性赋值>3.5、变异系数<25%、不重要百分比(包括不太重要和很不重要)<50%],建立药学人员科研指标评价体系。结果两轮专家函询均发放问卷36份,回收36份,回收率和有效率均为100%。两轮函询专家的判断系数平均值为0.912,熟悉程度平均值为0.747,专家权威系数平均值为0.830。经过第二轮函询后,一级指标的肯德尔协调系数为0.269,二级指标为0.379,三级指标为0.460,均显著高于第一轮专家函询结果(P<0.01)。最终确定了药学人员科研指标评价体系一级指标4个、二级指标18个、三级指标62个。结论本研究所选儿童医院药学专家权威性较高、专业覆盖面广;构建的药学人员科研指标评价体系具有一定的标准性和规范性,可为药学人员的专业水平考核、科研能力评价提供有力参考。 展开更多
关键词 科研能力评价 评价指标体系 儿童医院 儿科药师
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上海市儿童罕见病登记数据库建设和阶段性数据总结
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作者 李牛 李磊 +2 位作者 陈会文 王剑 张浩 《临床儿科杂志》 CAS CSCD 北大核心 2024年第2期102-109,共8页
目的总结上海市儿童罕见病登记数据库建设方案,并回顾性分析数据库中已收录患儿的人口学特征和疾病谱等资料,明确儿童罕见病病种分布特征,为建设高水平专病队列及系统管理罕见病患儿提供基础数据支持。方法基于国家罕见病注册系统病种... 目的总结上海市儿童罕见病登记数据库建设方案,并回顾性分析数据库中已收录患儿的人口学特征和疾病谱等资料,明确儿童罕见病病种分布特征,为建设高水平专病队列及系统管理罕见病患儿提供基础数据支持。方法基于国家罕见病注册系统病种目录以及各病种数据集,建成联通医院信息系统的区域儿童罕见病登记数据库,对数据库中患儿数据进行描述性研究分析。结果数据库1期共收录2008—2021年诊断的6341例罕见病患儿,覆盖109种疾病。门诊和住院患儿占比分别为59.4%(3764例)和40.6%(2577例),男女性别比为1.36︰1;占比较高的病种主要包括朗格汉斯细胞组织细胞增生症(11.3%)、家族性扩张型心肌病(7.9%)、血友病(5.5%)和神经纤维瘤(5.4%)等。伴随高通量测序技术的广泛应用,明确诊断的儿童罕见病患者数量逐年增加,>80%的患儿在10岁之前可获得明确诊断。结论本研究建立了同时纳入门诊和住院患儿的罕见病登记数据库,描述了儿童患者的疾病谱和人口学特征,并反映出中国近年来在这一领域的进步。该研究将为进一步纳入更多罕见病病种,并多中心建设更高水平儿童罕见病数据库提供基础数据。 展开更多
关键词 儿童罕见病 登记数据库 疾病谱 描述性研究
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特殊需要儿童执行功能研究进展
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作者 刘婷婷 肖永涛 《中国听力语言康复科学杂志》 2024年第3期275-279,共5页
特殊需要儿童多伴有执行功能障碍,执行功能障碍会对其生理、心理和社会层面产生不利影响。早期诊断和干预对特殊需要儿童的发展尤为重要。本文从特殊需要儿童的个性化差异特点出发,在广泛查阅、梳理国内外文献的基础上,归纳孤独症谱系... 特殊需要儿童多伴有执行功能障碍,执行功能障碍会对其生理、心理和社会层面产生不利影响。早期诊断和干预对特殊需要儿童的发展尤为重要。本文从特殊需要儿童的个性化差异特点出发,在广泛查阅、梳理国内外文献的基础上,归纳孤独症谱系障碍、注意缺陷多动障碍、听障这3类研究较多的特殊需要儿童执行功能发展研究进展,为深入研究和临床实验提供参考。 展开更多
关键词 特殊需要儿童 执行功能 研究进展
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近十年我国幼儿学习品质研究热点与启示──基于CiteSpace可视化分析
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作者 刘国艳 孔梓葳 +1 位作者 魏美香 詹雯琪 《宁波教育学院学报》 2024年第1期25-30,共6页
以中国知网(CNKI)数据库为文献来源,借助CiteSpace文献计量可视化软件绘制关键词共现知识图谱,对我国近十年来幼儿学习品质研究进行分析,发现我国幼儿学习品质研究热点领域主要为幼儿学习品质与幼儿发展、幼儿学习品质的影响因素、幼儿... 以中国知网(CNKI)数据库为文献来源,借助CiteSpace文献计量可视化软件绘制关键词共现知识图谱,对我国近十年来幼儿学习品质研究进行分析,发现我国幼儿学习品质研究热点领域主要为幼儿学习品质与幼儿发展、幼儿学习品质的影响因素、幼儿学习品质的培养。展望未来,幼儿学习品质研究应关注幼儿多元发展,深入探析因果关系;明确学习品质内涵,修正幼儿教师观念;拓宽研究对象范围,关注处境不利儿童;重视整体系统培养,促进学习品质发展。 展开更多
关键词 幼儿 学习品质 研究热点
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基于移情设计的儿童输液座椅设计方向研究
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作者 张莉 蒋晓楠 《设计》 2024年第5期119-122,共4页
儿童医疗器械和设施的特点是作为使用者的儿童和家长,两者的情感需求是共存的。虽然儿童医疗产品的功能在不断更新,但市场上的儿童医疗器械与设施仍然显得难以靠近,而且异常冰冷。课题利用移情设计方法,观察实际儿童输液情境中用户的真... 儿童医疗器械和设施的特点是作为使用者的儿童和家长,两者的情感需求是共存的。虽然儿童医疗产品的功能在不断更新,但市场上的儿童医疗器械与设施仍然显得难以靠近,而且异常冰冷。课题利用移情设计方法,观察实际儿童输液情境中用户的真实表现,获取用户潜在情感需求,并将情感进行转移至输液座椅产品设计,挖掘产品创新点,提出满足用户体验的设计方案,为儿童输液座椅设计的创新提供更多视角。 展开更多
关键词 移情设计 儿童 输液座椅 用户研究 设计方向
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规范化H2H营养管理模式在鼾症患儿加速康复中的应用研究
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作者 王娟 龚放华 《中国标准化》 2024年第12期317-320,共4页
目的:探究规范化H2H(Hospital To Home)营养管理模式在鼾症患儿加速康复中的应用效果。方法:便利选取云南省某三级综合医院儿科住院手术的92例鼾症患儿为研究对象,随机将其分为对照组和研究组,各46例。对照组予以常规营养管理模式,研究... 目的:探究规范化H2H(Hospital To Home)营养管理模式在鼾症患儿加速康复中的应用效果。方法:便利选取云南省某三级综合医院儿科住院手术的92例鼾症患儿为研究对象,随机将其分为对照组和研究组,各46例。对照组予以常规营养管理模式,研究组予以规范化H2H营养管理模式,对比两组患儿的营养状况及护理满意度。结果:研究组较对照组的营养状况好,护理满意度评分高(P<0.05)。结论:在鼾症患儿手术治疗后的加速康复护理中,运用规范化H2H营养管理模式,可使患儿获得个体化、针对性的营养护理指导,使得患儿的体格发育和营养状况得到较大的改善,有利于患儿的身心健康,同时可获得较好的护理满意度,值得进一步推广应用。 展开更多
关键词 规范化H2H营养管理 鼾症患儿 加速康复 应用研究
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国内流动儿童研究概况、热点与趋势——基于热点可视化的探析
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作者 徐华 潘金玉 任哲宣 《苏州科技大学学报(社会科学版)》 2024年第1期38-47,108,共11页
伴随着人口迁移由个体迁移向家庭迁移的转变,流动儿童问题逐渐受到学者的关注。利用CiteSpace可视化软件分析2001—2022年我国流动儿童研究的相关文献,探究流动儿童研究概况、热点以及发展趋势。结果显示:国内流动儿童研究经历了萌芽期... 伴随着人口迁移由个体迁移向家庭迁移的转变,流动儿童问题逐渐受到学者的关注。利用CiteSpace可视化软件分析2001—2022年我国流动儿童研究的相关文献,探究流动儿童研究概况、热点以及发展趋势。结果显示:国内流动儿童研究经历了萌芽期、快速增长期、多元发展期三个发展阶段,发文量变化与同期国家流动儿童相关政策的出台动态保持一致,目前流动儿童研究内容逐渐深入,研究角度呈现多样化;流动儿童研究机构与作者多处于独立研究状态,主要集中在教育学与心理学领域,目前机构合作以相同机构间的内部合作、不同机构之间的合作为主;研究热点与政策结合度较高,以教育、预防接种、社会支持和融入为方向;社会工作、影响因素、社会融入、子女随迁将是流动儿童研究的趋势。流动儿童领域未来研究可以社会生态系统为视角,构建流动儿童的社会支持体系,在微观层面加强教养、教育和交往支持,在中观层面发挥学校、社区和社工站的积极作用,在宏观层面完善以发展为导向的教育政策。 展开更多
关键词 流动儿童 研究热点 可视化 前沿演进 义务教育
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清瘟败毒饮加减对小儿川崎病(气血两燔证)的临床改善及对患儿血清炎症和免疫功能的影响
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作者 张小平 杨蕊华 +2 位作者 杜丽芳 孙晔 马晓路 《中华中医药学刊》 CAS 北大核心 2024年第10期35-39,共5页
目的观察清瘟败毒饮加减联合丙种球蛋白治疗小儿川崎病(气血两燔证)的临床疗效及其对患儿血清炎症和免疫功能的影响。方法选择2020年1月—2023年12月于医院心内科治疗的220例小儿川崎病患儿并随机分为两组,每组110例,其中对照组患儿予... 目的观察清瘟败毒饮加减联合丙种球蛋白治疗小儿川崎病(气血两燔证)的临床疗效及其对患儿血清炎症和免疫功能的影响。方法选择2020年1月—2023年12月于医院心内科治疗的220例小儿川崎病患儿并随机分为两组,每组110例,其中对照组患儿予以阿司匹林联合丙球蛋白治疗,观察组在对照组基础上联合清瘟败毒饮加减治疗。比较两组患儿的临床疗效、症状消失时间,以及治疗前后血清炎症因子水平、免疫功能、心功能变化。结果对照组患儿的有效率为90.91%(100/110),观察组患儿的有效率为98.18%(108/110),与对照组比较,观察组的有效率显著升高(P<0.05)。与对照组比较,观察组患儿的发热等典型临床症状消失时间明显缩短(P<0.01)。干预完成后,观察组患儿白介素-6(interleukin-6,IL-6)、C-反应蛋白(C-reactive protein,CRP)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)等血清炎症因子水平相较于对照组均明显降低(P<0.01)。干预前两组患儿的免疫功能指标水平无明显差异(P>0.05);干预完成后,观察组患儿CD_(4)^(+)和CD_(4)^(+)/CD_(8)^(+)水平相较于对照组明显升高,而CD_(8)^(+)水平明显下降,差异具有统计学意义(P<0.01,P<0.05);CD_(3)^(+)水平有上调趋势,但差异无统计学意义(P>0.05)。干预前两组患儿的心功能无明显差异(P>0.05);干预完成后,观察组患儿血清中心脏型脂肪酸结合蛋白(Heart-type fatty acid binding protein,h-FABP)及B型钠尿肽(B-type natriuretic peptide,BNP)水平相较于对照组均明显下降(P<0.01)。干预过程中所有患儿的主要不良反应有恶心呕吐、食欲不振、腹痛腹泻等,症状轻微,两组患儿的不良反应发生率无明显差异(P>0.05)。结论清瘟败毒饮加减联合丙球蛋白治疗小儿川崎病干预效果较好,对改善患儿临床症状、抑制炎症反应、保护心脏功能、调节免疫功能、不良反应有较好干预效果。 展开更多
关键词 清瘟败毒饮 小儿川崎病 气血两燔证 丙种球蛋白 免疫功能 炎症水平 临床研究
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基于家庭层面的儿童青少年近视防控影响因素定性研究 被引量:1
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作者 曹钰璇 李婷婷 +9 位作者 高振珊 杨凤 周攀峰 张向林 陈玉明 江唐军 刘锋 陶舒曼 陶芳标 伍晓艳 《中国健康教育》 北大核心 2024年第6期504-508,共5页
目的基于家庭层面,探讨影响儿童青少年近视防控的主要因素,为合理制定儿童青少年近视防控干预措施、政策提供理论参考。方法于2023年4-12月,采取非概率抽样法选取我国部分省市中参与过儿童青少年近视防控调查的120名家长开展焦点小组访... 目的基于家庭层面,探讨影响儿童青少年近视防控的主要因素,为合理制定儿童青少年近视防控干预措施、政策提供理论参考。方法于2023年4-12月,采取非概率抽样法选取我国部分省市中参与过儿童青少年近视防控调查的120名家长开展焦点小组访谈。基于社会生态学理论,采用Nvivo 12.0主题框架分析法对定性资料进行编码和分析。结果访谈结果显示,限制电子产品使用时间、多户外活动、定期复查视力、学校积极开展相关健康教育以及社区的积极宣传等是预防儿童青少年近视发生发展的促进因素;家长及儿童青少年时间紧张、家长视力保健行为意识薄弱、学校开展近视防控活动形式单一、学校未能很好落实视力筛查政策等是主要障碍因素。结论家长时间观念、视力保健行为意识较弱,学校层面近视防控活动形式单一,以及视力筛查制度等政策落实是预防儿童青少年近视发生发展的影响因素,故未来可通过开展健康教育、推进多样化近视防控活动、落实视力筛查制度等干预措施,延缓儿童青少年近视的发生发展。 展开更多
关键词 近视 儿童青少年 定性研究 影响因素
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