Roles of N-cadherin in cerebral cortical development:cooperation with membrane trafficking and actin cytoskeletal regulation

Cell adhesion plays pivotal roles in the morphogenesis of multicellular organisms.Epithelial cells form several types of cell-to-cell adhesion,including zonula occludens(tight junctions),zonula adhaerens(adherens junctions),and macula adhaerens(desmosomes).Although these adhesion complexes are basically observed only in epithelial cells,cadherins,which are the major cell adhesion molecules of adherens junctions,are expressed in both epithelial and non-epithelial tissues,including neural tissues(Kawauchi,2012).The cadherin superfamily consists of more than 100 members,but classic cadherins.

Transformed by Technology China is striving to meet global challenges by promoting international cooperation in sci-tech innovation

In recent years,China has made remarkable technological progress in a number of areas.Given this progress,it is crucial to rapidly transform technological results into productivity gains.

INTERNATIONAL COOPERATION PROMOTING THE DEVELOPMENT OF SCIENCE AND TECHNOLOGY

On the occasion of celebrating the 45th anniversary of the founding of the Chinese Academy of Sciences(CAS), in recalling the development history of the CAS’s international exchange and cooperation,we feel gratified to see that it has entered into an unprecedented era of dynamic expansion and progress. The CAS’s international cooperation experienced a stage of "exchange only with eastern countries" in its inceptive years and at a time of actual stagnation in"cultural revolution". It was the Third Session of the Eleventh Congress of the Chinese Communist

Beijing's 4th GTEF Glitters with Brainstorming Themes-Science and Technology,Brand and International Cooperation

Hosted by the China National Textile & Apparel Council,the fourth" Global Textile Economic Forum"was held in Beijing on March 23,2007.Based

Prospects for Science and Technology Cooperation belween the Guangdong-Hong Kong-Macao Greater Bay Area and Portugal under the Belt and Road Initiative

President Xi,focusing on building a new pattern of all-round opening up to the outside world and promoting the common prosperity and progress of all countries,put forward a major proposal for the construction of the Silk Road Economic Belt and the maritime Silk Road in twenty-first Century.The bay area economy as an important coastal economic form,is the highlight of the current international economic map,and is a significant symbol of the world's first-class coastal city.The international first-class bay areas,such as New York Bay area,San Francisco Bay area and Tokyo Bay area,are characterized by openness,innovation,livability and internationalization.The Guangdong-Hong Kong-Macao Greater Bay Area has four worldclass cities,name Guangzhou,Shenzhen,Hong Kong and Macao,and the Pearl River Delta city cluster.It has an open economic structure,efficient resource allocation ability,strong agglomeration and spillover function and development international communication network plays a core function of leading innovation and gathering radiation.It is an important growth pole for promoting the economic development of the maritime Silk Road and a leader in technological change.With the help of Portugal's geographical position on the maritime Silk Road and market access advantages within the EU system,the Greater Bay Area should further deepen scientific and technological cooperation,improve the ability of scientific and technological innovation of both sides,let the scientific research subjects of the bay area help Portugal's scientific and technological development,and enhance PortugaFs scientific and technological position in the EU.From the perspective of the Belt and Road Initiative,combined with the basic situation and cooperation of China,especially Guangdong,Hong Kong and Macao,and the development of science and technology in Portugal,this article explores the technological fields,policy measures that are suitable for scientific and technological cooperation between the two sides,and puts forward corresponding suggestions to contribute to the technological development of China,Portugal and the global economic and social sustainable development.

JOINT EFFORTS FOR FURTHER DEVELOPMENT——Prospects for Science and Technology Cooperation between Hong Kong and the Mainland

There is a long tradition of friendly exchange and cooperation between the Chinese Academy of Sciences (CAS) and the universities in Hong Kong. In recent years, both sides have been increasingly realizing the importance of furthering their Collaboration and exchange and the cooperation has become more active, laying greater

Feature and Tendency of Technology Transfer in Z-Park Patent Cooperation Network:From the Perspective of Global Optimal Path

Purpose:This study aims to provide a new framework for analyzing the path of technology diffusion in the innovation network at the regional level and industrial level respectively,which is conducive to the integration of innovation resources,the coordinated development of innovative subjects,and the improvement of innovation abilities.Design/methodology/approach:Based on the Z-Park patent cooperation data,we establish Inter-Enterprise Technology Transfer Network model and apply the concept of Pivotability to describe the key links of technology diffusion and quantify the importance of innovative partnerships.By measuring the topologically structural characteristics in the levels of branch park and the technosphere,this paper demonstrates how technology spreads and promotes overall innovation activities within the innovation network.Findings:The results indicate that:(1)Patent cooperation network of the Z-Park displays heterogeneity and the connections between the innovative subjects distribute extremely uneven.(2)Haidian park owns the highest pivotability in the IETTN model,yet the related inter-enterprise patent cooperation is mainly concentrated in its internal,failing to facilitate the technology diffusion across multiple branch parks.(3)Such fields as“electronics and information”and“advanced manufacturing”are prominent in the cross-technosphere cooperation,while fields such as“new energy”and“environmental protection technology”can better promote industrial integration.Research limitations:Only the part of the joint patent application is taken into account while establishing the patent cooperation network.The other factors that influence the mechanism of technology diffusion in the innovation network need to be further studied,such as financial capital,market competition,and personnel mobility,etc.Practical implications:The findings of this paper will provide useful information and suggestions for the administration and policy-making of high-tech parks.Originality/value:The value of this paper is to build a bridge between the massive amount of patent data and the nature of technology diffusion,and to develop a set of tools to analyze the nonlinear relations between innovative subjects.

Multi-Radio Cooperation Technology and Heterogeneous Network Convergence

The heterogeneous network convergence is the trend of future network development. However, many bottlenecks exist in the converged system such as high time delay, high energy consumption, and low data rate. Multi-Radio Cooperation (MRC) technology is specially designed to overcome these bottlenecks and to satisfy the requirements of heterogeneous network convergence. MRC can improve network capacity, reduce the energy consumption of radio devices, and decrease handover latency between heterogeneous networks by the cooperation of multiple radios, and by efficient management and feasible allocation of multi-radio resources. MRC makes real seamless heterogeneous network convergence possible.

AGRICULTURAL SCIENCE ＆ TECHNOLOGY

《Agricultural Science＆Technology》是我国第一家农业科技综合类英文期刊，袁隆平主编，湖南省农业科学院主办，安徽吴楚科技文化传播有限责任公司提供编辑出版支持，2008年为双月刊，国际公开发行。国内统一刊号CN43—1422/S，国际标准刊号ISSN1009—4229。该刊立足国内、面向世界，重点宣传国内农业科研实践、农业技术革新的成果；报道国内农业科研及相关领域的最新进展；介绍国内特色资源、农业生产与经济发展状况，以及我国与国际的农业学术交流和贸易情况。

Putting Faces to Names： Snapshots of Two Committee Meetings, 95 Years Apart, Emphasize Continuous International Cooperation in the Atmospheric Sciences

1.Introduction Spectacular advances have been made in the atmospheric sciences on a global level during a period of one hundred years or more,which is arguably most evident through"the quiet revolution of numerical weather prediction"(Bauer et

Evolutionarily Cooperative Stable of Science & Technology Alliance Under Self-organized Organization

The cooperative evolutionary stability under self-organized organization is discussed in this paper. The differences between the objects studied by cooperative game theory and the ones studied by cooperative game in science ＆ technology alliance are analyzed. The mutant probability of agent＇s utility under endoge- nous technical factor condition is analyzed. By clarifying the connotation of Pareto-dominate institution in cooperative game, the efficient and feasible managerial definition of Pareto-dominate Institution in science ＆ technology alliance is presented. The evolutionarily cooperative game for the agent in Pareto-dominate institution is explained. And then the necessary condition of cooperative evolutionary stabilization based on multi-agent utility＇s dynamic equilibrium is put forward. Finally, the model of alliance＇s utility＇s dynamic equilibrium under self-organization is established.

Chinese Science&Technology Exhibition in Cambodia

The China Science and Technology Museum(CSTM)launched a science and technology exhibition tour in Cambodia on December 13,2018.More than 60 high-tech items covering fields of basic science,life sciences and information technology went on display at the Union of Youth Federations of Cambodia-Phnom Penh Branch(UYFC-PP).

SCO Digital Technology Platform:A New Chapter of Cooperation

Recently, the Digital Technology Platform of Shanghai Cooperation Organization(SCO)(Платформа цифровых технологии стран ШОС, hereinafter referred to as the platform) was inaugurated, which, as an international exchange and cooperation platform based on the framework of the SCO, will promote exchanges and cooperation in the field of the digital economy among member states.

International Cooperation Projects in Research Center for Eco-Environmental Sciences Chinese Academy of Sciences

1. CERP The Cooperative Ecological Research Programme (CERP) is a joint plan to study the Man and Biosphere (MAB) ecosystem in our country, founded by Germany through UNESCO. The second-stage projects of CERP had been undertaken in 1991, including: (1) Study on the Ecological Strategy for the Urban Development of Tianjin City Exemplifying the large industrial city, it is to study the succession mechanism, cybernetic characteristics, and systems analytic methods of identification, simulation and planning, of the Social-Economic-Natural Com-

Shiheng Coal-fired Power Plant An example plant for digesting & assimilating imported technology Warmly welcome cooperation from abroad for its expansion project

Shiheng Coal-fired Power Plant,situated at the foot of thefamous Taishan Mountain and about 100 km southwestof Jinan,the capital of Shandong Province,is a major power plant inShandong Provincial Grid,with a total installed capacity of 735 MW,of which:Plant A 4 medium size generating units with a total capacityof 135 MW;Plant B two subcritical pressure 300 MW generating units.

Effect of distribution of fines on evolution of cooperation in spatial public goods game

In the realm of public goods game,punishment,as a potent tool,stands out for fostering cooperation.While it effectively addresses the first-order free-rider problem,the associated costs can be substantial.Punishers incur expenses in imposing sanctions,while defectors face fines.Unfortunately,these monetary elements seemingly vanish into thin air,representing a loss to the system itself.However,by virtue of the redistribution of fines to cooperators and punishers,not only can we mitigate this loss,but the rewards for these cooperative individuals can be enhanced.Based upon this premise,this paper introduces a fine distribution mechanism to the traditional pool punishment model.Under identical parameter settings,by conducting a comparative experiment with the conventional punishment model,the paper aims to investigate the impact of fine distribution on the evolution of cooperation in spatial public goods game.The experimental results clearly demonstrate that,in instances where the punishment cost is prohibitively high,the cooperative strategies of the traditional pool punishment model may completely collapse.However,the model enriched with fine distribution manages to sustain a considerable number of cooperative strategies,thus highlighting its effectiveness in promoting and preserving cooperation,even in the face of substantial punishment cost.

Discreet investors exert greater influence on cooperation in the public goods game

This paper studies the evolutionary process of cooperative behavior in a public goods game model with heterogeneous investment strategies in square lattices.In the proposed model,players are divided into defectors,cooperators and discreet investors.Among these,defectors do not participate in investing,discreet investors make heterogeneous investments based on the investment behavior and cooperation value of their neighbors,and cooperators invest equally in each neighbor.In real life,heterogeneous investment is often accompanied by time or economic costs.The discreet investors in this paper pay a certain price to obtain their neighbors'investment behavior and cooperation value,which quantifies the time and economic costs of the heterogeneous investment process.The results of Monte Carlo simulation experiments in this study show that discreet investors can effectively resist the invasion of the defectors,form a stable cooperative group and expand the cooperative advantage in evolution.However,when discreet investors pay too high a price,they lose their strategic advantage.The results in this paper help us understand the role of heterogeneous investment in promoting and maintaining human social cooperation.

MAGA-SCIENCE AND ITS INTERNATIONAL COOPERATION

Amajor part of basic research, mega-science aims mainly at acquiring scientific knowledge that can be shared by the whole of mankind, and at deepening the understanding of nature. In terms of its modes of investment and organization, megascience falls into two categories: the "engineering type", which needs large-scale research devices in a given place and to gather a definite number

Role Dynamic Allocation of Human-Robot Cooperation Based on Reinforcement Learning in an Installation of Curtain Wall

A real-time adaptive roles allocation method based on reinforcement learning is proposed to improve humanrobot cooperation performance for a curtain wall installation task.This method breaks the traditional idea that the robot is regarded as the follower or only adjusts the leader and the follower in cooperation.In this paper,a self-learning method is proposed which can dynamically adapt and continuously adjust the initiative weight of the robot according to the change of the task.Firstly,the physical human-robot cooperation model,including the role factor is built.Then,a reinforcement learningmodel that can adjust the role factor in real time is established,and a reward and actionmodel is designed.The role factor can be adjusted continuously according to the comprehensive performance of the human-robot interaction force and the robot’s Jerk during the repeated installation.Finally,the roles adjustment rule established above continuously improves the comprehensive performance.Experiments of the dynamic roles allocation and the effect of the performance weighting coefficient on the result have been verified.The results show that the proposed method can realize the role adaptation and achieve the dual optimization goal of reducing the sum of the cooperator force and the robot’s Jerk.

INTERNAITONAL COOPERATION IN MEDICAL EQUIPMENT TECHNOLOGY

There is a long history of failure in international cooperation in medical equip-ment technology.IFMBE and JSMEBE have made great efforts to remedy the situa-tion.Recently,JSMEBE is asked by Japanese Goverment to provide a guideline forthe activities.A committee was formed for 3 years,and as a result of extensive sur-vey studies by questionaries,interviews and correspondences,the final guideline waspublished (in Japanese) March 1993.It is available on request,and English transla-