This study proposes an effective method to enhance the accuracy of the Differential Quadrature Method(DQM)for calculating the dynamic characteristics of functionally graded beams by improving the form of discrete node...This study proposes an effective method to enhance the accuracy of the Differential Quadrature Method(DQM)for calculating the dynamic characteristics of functionally graded beams by improving the form of discrete node distribution.Firstly,based on the first-order shear deformation theory,the governing equation of free vibration of a functionally graded beam is transformed into the eigenvalue problem of ordinary differential equations with respect to beam axial displacement,transverse displacement,and cross-sectional rotation angle by considering the effects of shear deformation and rotational inertia of the beam cross-section.Then,ignoring the shear deformation of the beam section and only considering the effect of the rotational inertia of the section,the governing equation of the beam is transformed into the eigenvalue problem of ordinary differential equations with respect to beam transverse displacement.Based on the differential quadrature method theory,the eigenvalue problem of ordinary differential equations is transformed into the eigenvalue problem of standard generalized algebraic equations.Finally,the first several natural frequencies of the beam can be calculated.The feasibility and accuracy of the improved DQM are verified using the finite element method(FEM)and combined with the results of relevant literature.展开更多
In this paper, we define some new sets of non-elementary functions in a group of solutions x(t) that are sine and cosine to the upper limit of integration in a non-elementary integral that can be arbitrary. We are usi...In this paper, we define some new sets of non-elementary functions in a group of solutions x(t) that are sine and cosine to the upper limit of integration in a non-elementary integral that can be arbitrary. We are using Abel’s methods, described by Armitage and Eberlein. The key is to start with a non-elementary integral function, differentiating and inverting, and then define a set of three functions that belong together. Differentiating these functions twice gives second-order nonlinear ODEs that have the defined set of functions as solutions. We will study some of the second-order nonlinear ODEs, especially those that exhibit limit cycles. Using the methods described in this paper, it is possible to define many other sets of non-elementary functions that are giving solutions to some second-order nonlinear autonomous ODEs.展开更多
Agricultural cooperative economic organization for water-saving irrigation in arid areas is a new form of economic organization in production,operation and management during the application process of water-saving irr...Agricultural cooperative economic organization for water-saving irrigation in arid areas is a new form of economic organization in production,operation and management during the application process of water-saving irrigation technologies.Currently,there are few researches on this cooperative economic organization.In this study,connotations of cooperative economic organizations for water-saving irrigation are specifically defined,and the characteristics and functions of this cooperative economic organization are analyzed.Based on that,several suggestions are proposed on the continuous development of cooperative economic organizations for water-saving irrigation.展开更多
With Biolog Eco microplate, metabolic characteristics and functional diver-sity of carbon source in microflora of ponds were researched based on recitculating ponds and control ponds in order to explore effects of eco...With Biolog Eco microplate, metabolic characteristics and functional diver-sity of carbon source in microflora of ponds were researched based on recitculating ponds and control ponds in order to explore effects of eco-adjustments on microflo-ra in ponds. The results indicate that total number of bacterium, microbial metabolism activity, and diversity index in P7, P8, P1 and P2 kept higher, fol owed by P3, P4, P5 and P6. The utilization rate of microbes on sugars achieved the highest (31.0%-48.7%), fol owed by carboxylic acid (13.4%-18.0%), amino acid (10.1%-20.5%), polymers (9.4%-17.0%), biopolymer (5.7%-9.7%) and phenol (4.95%-7.50%). Principal component analysis divided microflora in different ponds, suggesting that microbial community has varied carbon source characteristics and nitrogen-containing compound and biopolymer metabolisms are most affected.展开更多
[Objective] This study aimed to investigate the functions and properties of the preliminarily determined characteristics listed in DUS test guideline of Tagetes L., and explore the representativeness and comprehensive...[Objective] This study aimed to investigate the functions and properties of the preliminarily determined characteristics listed in DUS test guideline of Tagetes L., and explore the representativeness and comprehensiveness of this group of characteristics in DUS test. [Method] Based on the functions and properties of the characteristics, the described plant part (s), observation stage, expression pattern and observation method of each characteristic were analyzed to illustrate the representativeness and comprehensiveness of the combination of this group of characteristics in above functions and properties. [Result] As for described plant part(s), there are 5 characteristics describing plant as a whole, 3 characteristics describing stem, 6 characteristics describing leaf, 23 characteristics describing flower and 1 characteristic describing physiological feature. As for observation stage, there are 1 characteristic needing to be observed in the stage of seedling, 1 characteristic in the stage of beginning of flowering and other 36 characteristics in the stage of fully flowering. As for the expression pattern, there are 10 qualitative characteristics, 9 pseudo-qualitative characteristics and 19 quantitative characteristics. As for the observation method, there are 30 characteristics using VG as the observation method, and 8 characteristics using MS. [Conclusion] In view of the variation and morphological properties of marigold, this group of characteristics are representative and comprehensive, and ensure the accuracy and easiness of DUS test of Tagetes L., thereby achieving the reasonable combination of characteristics in described plant parts, observation stages, expression patterns and observation methods.展开更多
In this study,the frequency characteristics of the turbulent wind and the effects of wind-wave coupling on the low-and high-frequency responses of semi-submersible floating offshore wind turbines(FOWT)are investigated...In this study,the frequency characteristics of the turbulent wind and the effects of wind-wave coupling on the low-and high-frequency responses of semi-submersible floating offshore wind turbines(FOWT)are investigated.Various wave load components,such as first-order wave loads,combined first-and second-order difference-frequency wave loads,combined first-and second-order sum-frequency wave loads,and first-and complete second-order wave loads are taken into consideration,while different turbulent environments are considered in aerodynamic loads.The com-parison is based on time histories and frequency spectra of platform motions and structural load responses and statistical values.The findings indicate that the second-order difference-frequency wave loads will significantly increase the natural frequency of low-frequency motion in the responses of the platform motion and structure load of the semi-submersible platform,which will cause structural fatigue damage.Under the action of turbulent wind,the influences of second-order wave loads on the platform motion and structural load response cannot be ignored,especially under extreme sea conditions.Therefore,in order to evaluate the dynamic responses of semi-submersible FOWT more accurately,the actual environment should be simulated more realistically.展开更多
Previous studies have shown that reduced sleep duration,sleep fragmentation,and decreased sleep quality in patients with Alzheimer's disease are related to dysfunction in orexin signaling.At the same time,blood-br...Previous studies have shown that reduced sleep duration,sleep fragmentation,and decreased sleep quality in patients with Alzheimer's disease are related to dysfunction in orexin signaling.At the same time,blood-brain barrier disruption is considered an early biomarker of Alzheimer's disease.However,currently no report has examined how changes in orexin signaling relate to changes in the blood-brain barrier of patients who have Alzheimer's disease with sleep insufficiency.This cross-sectional study included 50 patients with Alzheimer's disease who received treatment in 2019 at Beijing Tiantan Hospital.Patients were divided into two groups:those with insufficient sleep(sleep duration≤6 hours,n=19,age 61.58±8.54 years,10 men)and those with normal sleep durations(sleep duration>6 hours,n=31,age 63.19±10.09 years,18 men).Demographic variables were collected to evaluate cognitive function,neuropsychiatric symptoms,and activities of daily living.The levels of orexin,its receptor proteins,and several blood-brain barrier factors were measured in cerebrospinal fluid.Sleep insufficiency was associated with impaired overall cognitive function that spanned multiple cognitive domains.Furthermore,levels of orexin and its receptors were upregulated in the cerebrospinal fluid,and the blood–brain barrier was destroyed.Both these events precipitated each other and accelerated the progression of Alzheimer's disease.These findings describe the clinical characteristics and potential mechanism underlying Alzheimer's disease accompanied by sleep deprivation.Inhibiting the upregulation of elements within the orexin system or preventing the breakdown of the blood-brain barrier could thus be targets for treating Alzheimer's disease.展开更多
Euphemism is a linguistic concept and meanwhile a cultural phenomenon.It truly reflects the life and values of English people through history,thus is closely linked with the culture of English-speaking countries.Moreo...Euphemism is a linguistic concept and meanwhile a cultural phenomenon.It truly reflects the life and values of English people through history,thus is closely linked with the culture of English-speaking countries.Moreover,euphemism has significant social functions.It has been causing wide interest in people.Many linguistic researchers and scholars have done much research on it.Based on their achievements the author will have an exploration of the cultural characteristics and social functions of English euphemism.展开更多
Parameter estimation to alpha stable distribution is difficult for without a explicit probability density function. On the base of sample characteristic function,an iterative LAD parameter estimation algorithm for SaS...Parameter estimation to alpha stable distribution is difficult for without a explicit probability density function. On the base of sample characteristic function,an iterative LAD parameter estimation algorithm for SaS is discussed. The example illustrates that the algorithm is feasible and efficient.展开更多
The probability distributions of wave characteristics from three groups of sampled ocean data with different significant wave heights have been analyzed using two transformation functions estimated by non-parametric a...The probability distributions of wave characteristics from three groups of sampled ocean data with different significant wave heights have been analyzed using two transformation functions estimated by non-parametric and parametric methods. The marginal wave characteristic distribution and the joint density of wave properties have been calculated using the two transformations, with the results and accuracy of both transformations presented here. The two transformations deviate slightly between each other for the calculation of the crest and trough height marginal wave distributions, as well as the joint densities of wave amplitude with other wave properties. The transformation methods for the calculation of the wave crest and trough height distributions are shown to provide good agreement with real ocean data. Our work will help in the determination of the most appropriate transformation procedure for the prediction of extreme values.展开更多
The statistical probability and their variation regularity of the measurable characteristic parameters in the CO 2 arc welding droplet short circuiting transfer process have been studied. The statistical analysis sh...The statistical probability and their variation regularity of the measurable characteristic parameters in the CO 2 arc welding droplet short circuiting transfer process have been studied. The statistical analysis shows that the sensitivity of each characteristic parameter with regard to the variation of the short circuiting transfer process is different. The sensitivity of 4 kinds among these characteristic parameters is more intense than that of the short circuiting transfer frequency. In order to take account of the synthetic influence of these characteristic parameters, by means of the characteristic parameters synthetic value, a quantitative evaluation function is built up to describe and evaluate the short circuiting transfer process of CO 2 arc welding in real time. The testing shows that the evaluation function can give a suitable synthetic valuation for the short circuiting transfer process with a variety of welding variables.展开更多
Second-order axially moving systems are common models in the field of dynamics, such as axially moving strings, cables, and belts. In the traditional research work, it is difficult to obtain closed-form solutions for ...Second-order axially moving systems are common models in the field of dynamics, such as axially moving strings, cables, and belts. In the traditional research work, it is difficult to obtain closed-form solutions for the forced vibration when the damping effect and the coupling effect of multiple second-order models are considered.In this paper, Green's function method based on the Laplace transform is used to obtain closed-form solutions for the forced vibration of second-order axially moving systems. By taking the axially moving damping string system and multi-string system connected by springs as examples, the detailed solution methods and the analytical Green's functions of these second-order systems are given. The mode functions and frequency equations are also obtained by the obtained Green's functions. The reliability and convenience of the results are verified by several examples. This paper provides a systematic analytical method for the dynamic analysis of second-order axially moving systems, and the obtained Green's functions are applicable to different second-order systems rather than just string systems. In addition, the work of this paper also has positive significance for the study on the forced vibration of high-order systems.展开更多
In this paper, the characteristic function method is applied to seek traveling wave solutions of nonlinear partial differential equations in a unified way. We consider the Wu-Zhang equation (which describes (1 + 1)-di...In this paper, the characteristic function method is applied to seek traveling wave solutions of nonlinear partial differential equations in a unified way. We consider the Wu-Zhang equation (which describes (1 + 1)-dimensional disper-sive long wave). The equations governing the wave propagation consist of a pair of non linear partial differential equations. The characteristic function method reduces the system of nonlinear partial differential equations to a system of nonlinear ordinary differential equations which is solved via the shooting method, coupled with Rungekutta scheme. The results include kink-profile solitary wave solutions, periodic wave solutions and rational solutions. As an illustrative example, the properties of some soliton solutions for Wu-Zhang equation are shown by some figures.展开更多
In this paper, the normal Luenberger function observer design for second-order descriptor linear systems is considered. It is shown that the main procedure of the design is to solve a so-called second-order generalize...In this paper, the normal Luenberger function observer design for second-order descriptor linear systems is considered. It is shown that the main procedure of the design is to solve a so-called second-order generalized Sylvester-observer matrix equation. Based on an explicit parametric solution to this equation, a parametric solution to the normal Luenberger function observer design problem is given. The design degrees of freedom presented by explicit parameters can be further utilized to achieve some additional design requirements.展开更多
We employ the coherent thermal states(a kind of entangled states)in thermal field dynamics to establisha complete entangled state formalism expressing pseudo-classical representations of density operator for light fie...We employ the coherent thermal states(a kind of entangled states)in thermal field dynamics to establisha complete entangled state formalism expressing pseudo-classical representations of density operator for light field.Especially,the relationship between the coherent thermal state and the characteristic function and the positive Prepresentation in quantum optics theory are obtained.展开更多
It was proved that velocity-dependent infinitesima l symmetry transformations of nonholonomic systems have a characteristic functio nal structure, which could be formulated by means of an auxiliary symmetry tra nsform...It was proved that velocity-dependent infinitesima l symmetry transformations of nonholonomic systems have a characteristic functio nal structure, which could be formulated by means of an auxiliary symmetry tra nsformation function and is manifestly dependent upon constants of motion of th e system. An example was given to illustrate the applicability of the results.展开更多
A simple method for disturbance decoupling for matrix second-order linear systems is proposed directly in matrix second-order framework via Luenberger function observers based on complete parametric eigenstructure ass...A simple method for disturbance decoupling for matrix second-order linear systems is proposed directly in matrix second-order framework via Luenberger function observers based on complete parametric eigenstructure assignment. By introducing the H2 norm of the transfer function from disturbance to estimation error, sufficient and necessary conditions for disturbance decoupling in matrix second-order linear systems are established and are arranged into constraints on the design parameters via Luenberger function observers in terms of the closed-loop eigenvalues and the group of design parameters provided by the eigenstructure assignment approach. Therefore, the disturbance decoupling problem is converted into an eigenstructure assignment problem with extra parameter constraints. A simple example is investigated to show the effect and simplicity of the approach.展开更多
Further promotion of urbanization has resulted in the broken integrity of architectural environment and cultural system of traditional villages, and some traditional villages with historical architectural styles have ...Further promotion of urbanization has resulted in the broken integrity of architectural environment and cultural system of traditional villages, and some traditional villages with historical architectural styles have been on the verge of extinction. Against the background of building "beautiful Zhejiang and good life", Ningbo City has to optimize the livable environment continuously, integrate natural, humanistic, green, characteristic and comfortable elements into the beautiful countryside construction, thus it is urgent to explore the cultural characteristics and functions of architectural environment in traditional villages. Cultural characteristics and functions of architectural environment in traditional villages of Ningbo should be more systematic, legalized, and scientific. This paper reviewed concepts and cultural connotations of traditional villages, and integrated cultural characteristics and functions of regional architectural environment in traditional villages of Ningbo, and provided references for theoretic researches on the formation of characteristic regional architectural cultures in traditional villages of Ningbo.展开更多
The natural dynamic characteristics of a circular cylindrical tube made of three-directional(3 D)functional graded material(FGM)based on the Timoshenko beam theory are investigated.Hamilton’s principle is utilized to...The natural dynamic characteristics of a circular cylindrical tube made of three-directional(3 D)functional graded material(FGM)based on the Timoshenko beam theory are investigated.Hamilton’s principle is utilized to derive the novel motion equations of the tube,considering the interactions among the longitudinal,transverse,and rotation deformations.By dint of the differential quadrature method(DQM),the governing equations are discretized to conduct the analysis of natural dynamic characteristics.The Ritz method,in conjunction with the finite element method(FEM),is introduced to verify the present results.It is found that the asymmetric modes in the tube are controlled by the 3 D FGM,which exhibit more complicated shapes compared with the unidirectional(1 D)and bi-directional(2 D)FGM cases.Numerical examples illustrate the effects of the axial,radial,and circumferential FGM indexes as well as the supported edges on the natural dynamic characteristics in detail.It is notable that the obtained results are beneficial for accurate design of smart structures composed from multi-directional FGM.展开更多
In this paper, we define an exponential function whose exponent is the product of a real number and the upper limit of integration in a non-elementary integral that can be arbitrary. We are using Abel’s methods, desc...In this paper, we define an exponential function whose exponent is the product of a real number and the upper limit of integration in a non-elementary integral that can be arbitrary. We are using Abel’s methods, described by Armitage and Eberlein. The key is to start with a non-elementary integral function, differentiating and inverting, and then define a set of functions. Differentiating these functions twice give second-order nonlinear ODEs that have the defined set of functions as solutions.展开更多
基金Anhui Provincial Natural Science Foundation(2308085QD124)Anhui Province University Natural Science Research Project(GrantNo.2023AH050918)The University Outstanding Youth Talent Support Program of Anhui Province.
文摘This study proposes an effective method to enhance the accuracy of the Differential Quadrature Method(DQM)for calculating the dynamic characteristics of functionally graded beams by improving the form of discrete node distribution.Firstly,based on the first-order shear deformation theory,the governing equation of free vibration of a functionally graded beam is transformed into the eigenvalue problem of ordinary differential equations with respect to beam axial displacement,transverse displacement,and cross-sectional rotation angle by considering the effects of shear deformation and rotational inertia of the beam cross-section.Then,ignoring the shear deformation of the beam section and only considering the effect of the rotational inertia of the section,the governing equation of the beam is transformed into the eigenvalue problem of ordinary differential equations with respect to beam transverse displacement.Based on the differential quadrature method theory,the eigenvalue problem of ordinary differential equations is transformed into the eigenvalue problem of standard generalized algebraic equations.Finally,the first several natural frequencies of the beam can be calculated.The feasibility and accuracy of the improved DQM are verified using the finite element method(FEM)and combined with the results of relevant literature.
文摘In this paper, we define some new sets of non-elementary functions in a group of solutions x(t) that are sine and cosine to the upper limit of integration in a non-elementary integral that can be arbitrary. We are using Abel’s methods, described by Armitage and Eberlein. The key is to start with a non-elementary integral function, differentiating and inverting, and then define a set of three functions that belong together. Differentiating these functions twice gives second-order nonlinear ODEs that have the defined set of functions as solutions. We will study some of the second-order nonlinear ODEs, especially those that exhibit limit cycles. Using the methods described in this paper, it is possible to define many other sets of non-elementary functions that are giving solutions to some second-order nonlinear autonomous ODEs.
基金Supported by National Science and Technology Support Program(2007BAD38B09)~~
文摘Agricultural cooperative economic organization for water-saving irrigation in arid areas is a new form of economic organization in production,operation and management during the application process of water-saving irrigation technologies.Currently,there are few researches on this cooperative economic organization.In this study,connotations of cooperative economic organizations for water-saving irrigation are specifically defined,and the characteristics and functions of this cooperative economic organization are analyzed.Based on that,several suggestions are proposed on the continuous development of cooperative economic organizations for water-saving irrigation.
基金Supported by National Modern Agricultural Technology System(CARS-46)NationalSci-tech Support Plan(2012BAD25B05,2012BAD25B01)National Department PublicBenefit Research Foundation(201203083)~~
文摘With Biolog Eco microplate, metabolic characteristics and functional diver-sity of carbon source in microflora of ponds were researched based on recitculating ponds and control ponds in order to explore effects of eco-adjustments on microflo-ra in ponds. The results indicate that total number of bacterium, microbial metabolism activity, and diversity index in P7, P8, P1 and P2 kept higher, fol owed by P3, P4, P5 and P6. The utilization rate of microbes on sugars achieved the highest (31.0%-48.7%), fol owed by carboxylic acid (13.4%-18.0%), amino acid (10.1%-20.5%), polymers (9.4%-17.0%), biopolymer (5.7%-9.7%) and phenol (4.95%-7.50%). Principal component analysis divided microflora in different ponds, suggesting that microbial community has varied carbon source characteristics and nitrogen-containing compound and biopolymer metabolisms are most affected.
基金Supported by Special R&D Fund for National Public Service Sectors(Agriculture)of China(200903008-14)National 948 Project of China(2009-Z11)~~
文摘[Objective] This study aimed to investigate the functions and properties of the preliminarily determined characteristics listed in DUS test guideline of Tagetes L., and explore the representativeness and comprehensiveness of this group of characteristics in DUS test. [Method] Based on the functions and properties of the characteristics, the described plant part (s), observation stage, expression pattern and observation method of each characteristic were analyzed to illustrate the representativeness and comprehensiveness of the combination of this group of characteristics in above functions and properties. [Result] As for described plant part(s), there are 5 characteristics describing plant as a whole, 3 characteristics describing stem, 6 characteristics describing leaf, 23 characteristics describing flower and 1 characteristic describing physiological feature. As for observation stage, there are 1 characteristic needing to be observed in the stage of seedling, 1 characteristic in the stage of beginning of flowering and other 36 characteristics in the stage of fully flowering. As for the expression pattern, there are 10 qualitative characteristics, 9 pseudo-qualitative characteristics and 19 quantitative characteristics. As for the observation method, there are 30 characteristics using VG as the observation method, and 8 characteristics using MS. [Conclusion] In view of the variation and morphological properties of marigold, this group of characteristics are representative and comprehensive, and ensure the accuracy and easiness of DUS test of Tagetes L., thereby achieving the reasonable combination of characteristics in described plant parts, observation stages, expression patterns and observation methods.
基金supported by the Natural Science Foundation of Zhejiang Province(Grant No.LHZ21E090003)the National Nature Science Foundation of China(Grant No.52171279)+1 种基金Zhoushan Science&Technology Project(Grant No.2021C21002)supported by CNPq(Conselho Nacional de Desenvolvimento Científico e Tecnológico,Grant No.301474/2017-6).
文摘In this study,the frequency characteristics of the turbulent wind and the effects of wind-wave coupling on the low-and high-frequency responses of semi-submersible floating offshore wind turbines(FOWT)are investigated.Various wave load components,such as first-order wave loads,combined first-and second-order difference-frequency wave loads,combined first-and second-order sum-frequency wave loads,and first-and complete second-order wave loads are taken into consideration,while different turbulent environments are considered in aerodynamic loads.The com-parison is based on time histories and frequency spectra of platform motions and structural load responses and statistical values.The findings indicate that the second-order difference-frequency wave loads will significantly increase the natural frequency of low-frequency motion in the responses of the platform motion and structure load of the semi-submersible platform,which will cause structural fatigue damage.Under the action of turbulent wind,the influences of second-order wave loads on the platform motion and structural load response cannot be ignored,especially under extreme sea conditions.Therefore,in order to evaluate the dynamic responses of semi-submersible FOWT more accurately,the actual environment should be simulated more realistically.
基金supported by the National Key Research and Development Program of China,Nos.2016YFC1306300(to XMW),2016YFC1306000the National Key R&D Program of China-European Commission Horizon 2020,No.2017YFE0118800-779238(to YXW)+15 种基金the Notional Natural Science Foundation of Chino,Nos.81970992(to WZ),81571229(to WZ),81071015(to WZ),30770745(to WZ)Capital's Funds for Health Improvement and Research(CFH),No.2022-2-2048(to WZ)the Key Technology R&D Program of Beijing Municipal Education Commission,No.kz201610025030(to WZ)the Natural Science Foundation of Beijing,No.7082032(to WZ)the Key Project of the Natural Science Foundation of Beijing,No.4161004(to WZ)Capitol Clinical Characteristic Applicotion Research,No.Z121107001012161(to WZ)Project of Scientific and Technological Development of Traditional Chinese Medicine in Beijing,No.JJ2018-48(to WZ)High Level Technical Personnel Training Project of Beijing Health System of China,No.2009-3-26(to WZ)Excellent Personnel Training Project of Beijing,No.20071D0300400076(to WZ)Important National Science&Technology Specific Project,No.2011ZX09102-003-01(to WZ)Beijing Healthcare Research Project,No.JING-15-2(to WZ)Basic-Clinicol Research Cooperation Funding of Capitol Medical University of China,Nos.2015-JL-PT-X04(to WZ),10JL49(to WZ),14JL15(to WZ)the Natural Science Foundation of Capital Medical UniversityBeijingChina,No.PYZ2018077(to PG)Youth Research Fund of Beijing Tianton Hospital of Capital Medical University of China,Nos.2015-YQN-14(to PG),2015-YQN-15,2015-YQN-17。
文摘Previous studies have shown that reduced sleep duration,sleep fragmentation,and decreased sleep quality in patients with Alzheimer's disease are related to dysfunction in orexin signaling.At the same time,blood-brain barrier disruption is considered an early biomarker of Alzheimer's disease.However,currently no report has examined how changes in orexin signaling relate to changes in the blood-brain barrier of patients who have Alzheimer's disease with sleep insufficiency.This cross-sectional study included 50 patients with Alzheimer's disease who received treatment in 2019 at Beijing Tiantan Hospital.Patients were divided into two groups:those with insufficient sleep(sleep duration≤6 hours,n=19,age 61.58±8.54 years,10 men)and those with normal sleep durations(sleep duration>6 hours,n=31,age 63.19±10.09 years,18 men).Demographic variables were collected to evaluate cognitive function,neuropsychiatric symptoms,and activities of daily living.The levels of orexin,its receptor proteins,and several blood-brain barrier factors were measured in cerebrospinal fluid.Sleep insufficiency was associated with impaired overall cognitive function that spanned multiple cognitive domains.Furthermore,levels of orexin and its receptors were upregulated in the cerebrospinal fluid,and the blood–brain barrier was destroyed.Both these events precipitated each other and accelerated the progression of Alzheimer's disease.These findings describe the clinical characteristics and potential mechanism underlying Alzheimer's disease accompanied by sleep deprivation.Inhibiting the upregulation of elements within the orexin system or preventing the breakdown of the blood-brain barrier could thus be targets for treating Alzheimer's disease.
文摘Euphemism is a linguistic concept and meanwhile a cultural phenomenon.It truly reflects the life and values of English people through history,thus is closely linked with the culture of English-speaking countries.Moreover,euphemism has significant social functions.It has been causing wide interest in people.Many linguistic researchers and scholars have done much research on it.Based on their achievements the author will have an exploration of the cultural characteristics and social functions of English euphemism.
基金Supported by Hubei Educational Committee grant Q20091809Wuhan Polytechnic University grant 2009Y21
文摘Parameter estimation to alpha stable distribution is difficult for without a explicit probability density function. On the base of sample characteristic function,an iterative LAD parameter estimation algorithm for SaS is discussed. The example illustrates that the algorithm is feasible and efficient.
基金Supported by the Marine Engineering Equipment Scientific Research Project of Ministry of Industry and Information Technology of PRCthe National Science and Technology Major Project of China(Grant No.2016ZX05057020)National Natural Science Foundation of China(Grant No.51809067)
文摘The probability distributions of wave characteristics from three groups of sampled ocean data with different significant wave heights have been analyzed using two transformation functions estimated by non-parametric and parametric methods. The marginal wave characteristic distribution and the joint density of wave properties have been calculated using the two transformations, with the results and accuracy of both transformations presented here. The two transformations deviate slightly between each other for the calculation of the crest and trough height marginal wave distributions, as well as the joint densities of wave amplitude with other wave properties. The transformation methods for the calculation of the wave crest and trough height distributions are shown to provide good agreement with real ocean data. Our work will help in the determination of the most appropriate transformation procedure for the prediction of extreme values.
文摘The statistical probability and their variation regularity of the measurable characteristic parameters in the CO 2 arc welding droplet short circuiting transfer process have been studied. The statistical analysis shows that the sensitivity of each characteristic parameter with regard to the variation of the short circuiting transfer process is different. The sensitivity of 4 kinds among these characteristic parameters is more intense than that of the short circuiting transfer frequency. In order to take account of the synthetic influence of these characteristic parameters, by means of the characteristic parameters synthetic value, a quantitative evaluation function is built up to describe and evaluate the short circuiting transfer process of CO 2 arc welding in real time. The testing shows that the evaluation function can give a suitable synthetic valuation for the short circuiting transfer process with a variety of welding variables.
基金Project supported by the National Natural Science Foundation of China (No. 12272323)。
文摘Second-order axially moving systems are common models in the field of dynamics, such as axially moving strings, cables, and belts. In the traditional research work, it is difficult to obtain closed-form solutions for the forced vibration when the damping effect and the coupling effect of multiple second-order models are considered.In this paper, Green's function method based on the Laplace transform is used to obtain closed-form solutions for the forced vibration of second-order axially moving systems. By taking the axially moving damping string system and multi-string system connected by springs as examples, the detailed solution methods and the analytical Green's functions of these second-order systems are given. The mode functions and frequency equations are also obtained by the obtained Green's functions. The reliability and convenience of the results are verified by several examples. This paper provides a systematic analytical method for the dynamic analysis of second-order axially moving systems, and the obtained Green's functions are applicable to different second-order systems rather than just string systems. In addition, the work of this paper also has positive significance for the study on the forced vibration of high-order systems.
文摘In this paper, the characteristic function method is applied to seek traveling wave solutions of nonlinear partial differential equations in a unified way. We consider the Wu-Zhang equation (which describes (1 + 1)-dimensional disper-sive long wave). The equations governing the wave propagation consist of a pair of non linear partial differential equations. The characteristic function method reduces the system of nonlinear partial differential equations to a system of nonlinear ordinary differential equations which is solved via the shooting method, coupled with Rungekutta scheme. The results include kink-profile solitary wave solutions, periodic wave solutions and rational solutions. As an illustrative example, the properties of some soliton solutions for Wu-Zhang equation are shown by some figures.
基金This work was supported by National Natural Science Foundation of China(No.60710002)Program for Changjiang Scholars and Innovative Research Team in University(PCSIRT).
文摘In this paper, the normal Luenberger function observer design for second-order descriptor linear systems is considered. It is shown that the main procedure of the design is to solve a so-called second-order generalized Sylvester-observer matrix equation. Based on an explicit parametric solution to this equation, a parametric solution to the normal Luenberger function observer design problem is given. The design degrees of freedom presented by explicit parameters can be further utilized to achieve some additional design requirements.
基金the President Foundation of the Chinese Academy of Sciences
文摘We employ the coherent thermal states(a kind of entangled states)in thermal field dynamics to establisha complete entangled state formalism expressing pseudo-classical representations of density operator for light field.Especially,the relationship between the coherent thermal state and the characteristic function and the positive Prepresentation in quantum optics theory are obtained.
文摘It was proved that velocity-dependent infinitesima l symmetry transformations of nonholonomic systems have a characteristic functio nal structure, which could be formulated by means of an auxiliary symmetry tra nsformation function and is manifestly dependent upon constants of motion of th e system. An example was given to illustrate the applicability of the results.
文摘A simple method for disturbance decoupling for matrix second-order linear systems is proposed directly in matrix second-order framework via Luenberger function observers based on complete parametric eigenstructure assignment. By introducing the H2 norm of the transfer function from disturbance to estimation error, sufficient and necessary conditions for disturbance decoupling in matrix second-order linear systems are established and are arranged into constraints on the design parameters via Luenberger function observers in terms of the closed-loop eigenvalues and the group of design parameters provided by the eigenstructure assignment approach. Therefore, the disturbance decoupling problem is converted into an eigenstructure assignment problem with extra parameter constraints. A simple example is investigated to show the effect and simplicity of the approach.
基金Sponsored by 2015 Ningbo Science and Technology Planning Project(2015A10024)
文摘Further promotion of urbanization has resulted in the broken integrity of architectural environment and cultural system of traditional villages, and some traditional villages with historical architectural styles have been on the verge of extinction. Against the background of building "beautiful Zhejiang and good life", Ningbo City has to optimize the livable environment continuously, integrate natural, humanistic, green, characteristic and comfortable elements into the beautiful countryside construction, thus it is urgent to explore the cultural characteristics and functions of architectural environment in traditional villages. Cultural characteristics and functions of architectural environment in traditional villages of Ningbo should be more systematic, legalized, and scientific. This paper reviewed concepts and cultural connotations of traditional villages, and integrated cultural characteristics and functions of regional architectural environment in traditional villages of Ningbo, and provided references for theoretic researches on the formation of characteristic regional architectural cultures in traditional villages of Ningbo.
基金Project supported by the National Natural Science Foundation of China(Nos.11902001 and12072221)the China Postdoctoral Science Foundation(No.2018M641643)the Anhui Provincial Natural Science Foundation of China(Nos.1908085QA13 and 1808085ME128)。
文摘The natural dynamic characteristics of a circular cylindrical tube made of three-directional(3 D)functional graded material(FGM)based on the Timoshenko beam theory are investigated.Hamilton’s principle is utilized to derive the novel motion equations of the tube,considering the interactions among the longitudinal,transverse,and rotation deformations.By dint of the differential quadrature method(DQM),the governing equations are discretized to conduct the analysis of natural dynamic characteristics.The Ritz method,in conjunction with the finite element method(FEM),is introduced to verify the present results.It is found that the asymmetric modes in the tube are controlled by the 3 D FGM,which exhibit more complicated shapes compared with the unidirectional(1 D)and bi-directional(2 D)FGM cases.Numerical examples illustrate the effects of the axial,radial,and circumferential FGM indexes as well as the supported edges on the natural dynamic characteristics in detail.It is notable that the obtained results are beneficial for accurate design of smart structures composed from multi-directional FGM.
文摘In this paper, we define an exponential function whose exponent is the product of a real number and the upper limit of integration in a non-elementary integral that can be arbitrary. We are using Abel’s methods, described by Armitage and Eberlein. The key is to start with a non-elementary integral function, differentiating and inverting, and then define a set of functions. Differentiating these functions twice give second-order nonlinear ODEs that have the defined set of functions as solutions.