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Risk factors in cardiovascular patients:Challenges and opportunities to improve secondary prevention 被引量:1
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作者 Rahima Gabulova Anna Marzà-Florensa +12 位作者 Uzeyir Rahimov Mahluga Isayeva Shahana Alasgarli Afag Musayeva Sona Gahramanova Firdovsi Ibrahimov Farid Aliyev Galib Imanov Rahmana Rasulova Ilonca Vaartjes Kerstin Klipstein-Grobusch Ian Graham Diederick E Grobbee 《World Journal of Cardiology》 2023年第7期342-353,共12页
BACKGROUND Effective management of major cardiovascular risk factors is of great importance to reduce mortality from cardiovascular disease(CVD).The Survey of Risk Factors in Coronary Heart Disease(SURF CHD)II study i... BACKGROUND Effective management of major cardiovascular risk factors is of great importance to reduce mortality from cardiovascular disease(CVD).The Survey of Risk Factors in Coronary Heart Disease(SURF CHD)II study is a clinical audit of the recording and management of CHD risk factors.It was developed in collaboration with the European Association of Preventive Cardiology and the European Society of Cardiology(ESC).Previous studies have shown that control of major cardiovascular risk factors in patients with established atherosclerotic CVD is generally inadequate.Azerbaijan is a country in the South Caucasus,a region at a very high risk for CVD.AIM To assess adherence to ESC recommendations for secondary prevention of CVD based on the measurement of both modifiable major risk factors and their therapeutic management in patients with confirmed CHD at different hospitals in Baku(Azerbaijan).METHODS Six tertiary health care centers participated in the SURF CHD II study between 2019 and 2021.Information on demographics,risk factors,physical and laboratory data,and medications was collected using a standard questionnaire in consecutive patients aged≥18 years with established CHD during outpatient visits.Data from 687 patients(mean age 59.6±9.58 years;24.9%female)were included in the study.RESULTS Only 15.1%of participants were involved in cardiac rehabilitation programs.The rate of uncontrolled risk factors was high:Systolic blood pressure(BP)(SBP)(54.6%),low-density lipoprotein cholesterol(LDL-C)(86.8%),diabetes mellitus(DM)(60.6%),as well as overweight(66.6%)and obesity(25%).In addition,significant differences in the prevalence and control of some risk factors[smoking,body mass index(BMI),waist circumference,blood glucose(BG),and SBP]between female and male participants were found.The cardiovascular health index score(CHIS)was calculated from the six risk factors:Non-or ex-smoker,BMI<25 kg/m2,moderate/vigorous physical activity,controlled BP(<140/90 mmHg;140/80 mmHg for patients with DM),controlled LDL-C(<70 mg/dL),and controlled BG(glycohemoglobin<7%or BG<126 mg/dL).Good,intermediate,and poor categories of CHIS were identified in 6%,58.3%,and 35.7%of patients,respectively(without statistical differences between female and male patients).CONCLUSION Implementation of the current ESC recommendations for CHD secondary prevention and,in particular,the control rate of BP,are insufficient.Given the fact that patients with different comorbid pathologies are at a very high risk,this is of great importance in the management of such patients.This should be taken into account by healthcare organizers when planning secondary prevention activities and public health protection measures,especially in the regions at a high risk for CVD.A wide range of educational products based on the Clinical Practice Guidelines should be used to improve the adherence of healthcare professionals and patients to the management of CVD risk factors. 展开更多
关键词 Coronary heart disease Cardiovascular risk factors secondary prevention Clinical practice guidelines Clinical audit Survey of risk factors
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Characteristics and Prevention of Secondary Geological Disasters of Wenchuan Earthquake 被引量:4
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作者 宋鄂平 张克信 +1 位作者 卢炎秋 孙毅 《Agricultural Science & Technology》 CAS 2013年第7期1044-1048,共5页
In the research, secondary geological disasters of Wenchuan earthquake were defined and the consequences were illustrated based on geological disasters, such as collapse, landslide and debris flow, and threats of barr... In the research, secondary geological disasters of Wenchuan earthquake were defined and the consequences were illustrated based on geological disasters, such as collapse, landslide and debris flow, and threats of barrier lakes. In addition, the characteristics of secondary disasters were analyzed, as follows: Rupture of geological faults lays foundation in terms of geological structure; loose solids provide resources of an earthquake; abundant rainfall and large runoffs are driving forces of an earthquake; rainstorm, flood, and long-term high temperature are major inducing factors. Furthermore, suggestions on prevention of secondary disasters were proposed in terms of prevention before, at and after an earthquake. Finally, the scientific and practical significances of secondary disasters were illustrated. 展开更多
关键词 Wenchuan earthquake secondary geological disaster CHARACTERISTICS prevention
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Myocardial infarction secondary prevention study (MISPS) 被引量:14
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作者 Hongcai SHANG Guohua DAI Junhua HANG Yaozu XIANG Yang WANG Junping ZHANG Wuxun DU Jingyuan MAO Chen YAO Weiliang WENG Tiancai WEN Boli ZHANG 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2006年第2期116-119,共4页
Background Traditional Chinese medicine (TCM), especially herbal medicine, has been widely used in China and now is also being increasingly used in other countries for the treatment of cardiovascular diseases. Althoug... Background Traditional Chinese medicine (TCM), especially herbal medicine, has been widely used in China and now is also being increasingly used in other countries for the treatment of cardiovascular diseases. Although many studies have demonstrated that certain Chinese herbal products are effective and safe for the treatment of cardiovascular diseases, most of these lack sufficient quality. Therefore, large randomized clinical trials and further scientific research to determine its safety, effectiveness are necessary.QiShen YiQi Dripping Pills (QSYQDP) is a herbal preparation clinically used in the treatment and prevention of coronary artery disease. Preliminary observations have shown its safety and effectiveness. Methods/Design This randomized, controlled trial will recruit 3600 patients with a history of myocardial infarction. Patients will be randomized into two groups by a Centr-Randomized System. One group receives QSYQDP, the other group receive aspirin. This trial protocol will describe eligibility criteria, detailed information on the treatment definition, blinding, endpoints, statistical methods, sample size determination, data management, legal aspects, and the current status of the trial. Discussion This trial is one of the first randomized, controlled clinical trial to evaluate the efficacy and safety of traditional Chinese herbal medicine in the treatment and secondary prevention of coronary artery disease. The results of this study should help to define the role of TCM in modern medical care, as well as to provide the management strategy for CAD patients in China and other countries. 展开更多
关键词 Myocardial infarction secondary prevention study MISPS MACE
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Cardiac rehabilitation and its essential role in the secondary prevention of cardiovascular diseases 被引量:10
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作者 Petr Winnige Robert Vysoky +1 位作者 Filip Dosbaba Ladislav Batalik 《World Journal of Clinical Cases》 SCIE 2021年第8期1761-1784,共24页
Cardiovascular diseases are the most common causes of mortality worldwide.They are frequently the reasons for patient hospitalization,their incapability for work,and disability.These diseases represent a significant s... Cardiovascular diseases are the most common causes of mortality worldwide.They are frequently the reasons for patient hospitalization,their incapability for work,and disability.These diseases represent a significant socio-economic burden affecting the medical system as well as patients and their families.It has been demonstrated that the etiopathogenesis of cardiovascular diseases is significantly affected by lifestyle,and so modification of the latter is an essential component of both primary and secondary prevention.Cardiac rehabilitation(CR)represents an efficient secondary prevention model that is especially based on the positive effect of regular physical activity.This review presents an overview of basic information on CR with a focus on current trends,such as the issue of the various training modalities,utilization,and barriers to it or the use of telemedicine technologies.Appropriate attention should be devoted to these domains,as CR continues evolving as an effective and readily available intervention in the future. 展开更多
关键词 Cardiac rehabilitation secondary prevention Cardiovascular diseases UTILIZATION Barriers TELEREHABILITATION
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Secondary prevention of recurrence by interferon therapy after ablation therapy for hepatocellular carcinoma in chronic hepatitis C patients 被引量:5
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作者 Toru Ishikawa 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第40期6140-6144,共5页
Chronic hepatitis C is a leading cause of hepatocellular carcinoma (HCC) worldwide.Interferon (IFN) ther-apy decreases the incidence of HCC in patients with chronic hepatitis C.Prevention of chronic-hepatitis-C-relate... Chronic hepatitis C is a leading cause of hepatocellular carcinoma (HCC) worldwide.Interferon (IFN) ther-apy decreases the incidence of HCC in patients with chronic hepatitis C.Prevention of chronic-hepatitis-C-related HCC is one of the most important issues in current hepatology.We have previously reported that male gender and high titer of hepatitis C virus (HCV) RNA are predictive factors for the development of HCC in HCV-related cirrhosis.Clinical efforts at eradicat-ing or reducing the viral load may reduce the risk for HCC.Furthermore,because HCC often recurs after ablation therapy,we performed a trial of IFN in pa-tients with chronic liver disease caused by HCV to see whether IFN therapy decreases recurrence after abla-tion therapy of HCV-related HCC.By using IFN therapy as a secondary prevention,patients with HCC who had received complete tumor ablation showed better sur-vival,primarily as a result of the preservation of liver function and also probably prevention of recurrence.Postoperative IFN therapy appears to decrease recur-rence after ablation therapy such as radiofrequency ablation (RFA) therapy of HCV-related HCC.We believe that there is a survival benefit in secondary prevention using IFN therapy.However,a controlled study is es-sential to obtain conclusive evidence of the efficacy of this strategy. 展开更多
关键词 Hepatocellular carcinoma Radiofrequency ablation INTERFERON secondary prevention
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Awareness intervention for Beijing neurologists regarding secondary prevention of cerebral infarction/transient ischemia Cross-sectional investigation 被引量:2
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作者 Ruihua Ma Chunxue Wang +15 位作者 Xianwei Wang Yuhui Zhang Yongjun Wang Yilong Wang Xingquan Zhao Jingjing Li Ying Lu Mingjie Xu Zhuo Zhang Li Wang Weiwei Zhang Lang Lin Jiping Tan Yao Li Ming Wei Hongtao Li 《Neural Regeneration Research》 SCIE CAS CSCD 2008年第3期333-336,共4页
BACKGROUND: Stroke prevention guidelines should be made available application to aid in uniformity, timing, preciseness, and acceptance of disease. OBJECTIVE: To investigate the awareness of neurologists in some Bei... BACKGROUND: Stroke prevention guidelines should be made available application to aid in uniformity, timing, preciseness, and acceptance of disease. OBJECTIVE: To investigate the awareness of neurologists in some Beijing secondary prevention of cerebral infarction/transient ischemia. DESIGN: Cross-sectional study. to neurologists for clinical hospitals of intervention in SETTING: Beijing Tiantan Hospital, Beijing Anzhen Hospital, General Hospital of Beijing Military Area, Command of Chinese PLA, Beijing Chuiyangliu Hospital, Beijing 6^th Hospital, Beijing Hepingli Hospital, and Beijing Daxing District Hospital. PARTICIPANTS: A total of 28 (associate) chief physicians, 58 attending physicians, and 54 resident physicians who engaged in clinical treatment of cerebrovascular diseases were selected from 8 hospitals in Beijing from March to April 2007. All physicians provided informed consent. METHODS: Self-made closed questionnaires were provided for data collection, consisting of 16 questions that were single choice or multiple choice. Specifically, questions 1-7 focused on awareness of blood pressure regulation in different patients and first choice of decompression drug; questions 8-12 focused on awareness of lipid regulation; and questions 13-16 focused on awareness of anti-blood platelet drugs applied in secondary prevention. The scores ranged from 0-100 points, and each question was worth 6.25 points. The scores positively correlated with the awareness rate. To test leveling real-time, the survey lasted for a maximum of 20 minutes. One questionnaire was independently finished by each subject in the survey. MAIN OUTCOME MEASURES: Awareness intervention among neurologists during secondary prevention of cerebral infarction/transient ischemia and questionnaire scores. RESULTS: 140 subjects were included in the final analysis. ① The awareness rate among neurologists for intervention during secondary prevention of cerebral infarction/transient ischemia ranged from 0.7-57.9%, the scores ranged between 0-56 points, and the mean score was 26 points.② Scores of resident physicians were 0-56 points with a mean score of 26 points; attending physicians scored 6-50 points, with a mean score of 26 points; and chief physicians scored 6-50 points, with a mean score of 23 points. There were no significant differences among the various physicians (F = 0.771, t = 0.465, P 〉 0.05). CONCLUSION: Awareness among neurologists of intervention during secondary prevention of cerebral infarction/transient ischemia is not ideal. However, there was no significant difference between professional titles. 展开更多
关键词 secondary prevention cerebral infarction transient ischemic attack cross-sectional study
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Physical activity in primary and secondary prevention of cardiovascular disease:Overview updated 被引量:7
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作者 Alberto J Alves Joao L Viana +5 位作者 Suiane L Cavalcante Nórton L Oliveira JoséA Duarte Jorge Mota JoséOliveira Fernando Ribeiro 《World Journal of Cardiology》 2016年第10期575-583,共9页
Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries... Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries. Three-quarters of deaths due to cardiovascular diseases could be prevented with adequate changes in lifestyle, including increased daily physical activity. New evidence confirms that there is an inverse dose-response relationship between physical activity and cardiovascular disease and mortality risk. However, participation in moderate to vigorous physical activity may not fully attenuate the independent effect of sedentary activities on increased risk for cardiovascular diseases. Physical activity also plays an important role in secondary prevention of cardiovascular diseases by reducing the impact of the disease, slowing its progress and preventing recurrence. Nonetheless, most of eligible cardiovascular patients still do not benefit from secondary prevention/cardiac rehabilitation programs. The present review draws attention to the importance of physical activity in the primary and secondary prevention of cardiovascular diseases. It also addresses the mechanisms by which physical activity and regular exercise can improve cardiovascular health and reduce the burden of the disease. 展开更多
关键词 Physical activity Primary prevention secondary prevention Cardiovascular disease Health care evaluation mechanisms
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The influence of treatment modality on illness perception and secondary prevention outcomes among patients with acute myocardial infarction 被引量:3
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作者 Ahmed Mohammad Al-Smadi Loai Issa Tawalbeh +4 位作者 Ala Ashour Issa M.Hweidi Besher Gharaibeh Paul Slater Donna Fitzsimons 《International Journal of Nursing Sciences》 2017年第3期271-277,共7页
Objectives:This study aims to determine if patients with acute myocardial infarction differ in illness perception and secondary prevention outcomes depending on the treatment they received.Methods:A repeated measures ... Objectives:This study aims to determine if patients with acute myocardial infarction differ in illness perception and secondary prevention outcomes depending on the treatment they received.Methods:A repeated measures design was used to compare patients with acute myocardial infarction receiving three different treatment modalities:ST-elevation myocardial infarction treated by primary percutaneous coronary intervention,ST-elevation myocardial infarction treated by thrombolytic therapy,and non ST-elevation myocardial infarction treated by medication.A convenient sampling technique was used to recruit 206 patients with acute myocardial infarction who agreed to participate in the current study.Patients'illness perception,physical activity,and demographical and clinical data were collected during hospital admission and again at 6 months.Results:A total of 186 patients completed the study.Results showed that the primary percutaneous coronary intervention group perceived their illness as acute rather than chronic(P=0.034)and has lower personal control(P=0.032),higher treatment control(P=0.025),and higher perception of illness coherence(P=0.022)compared with patients receiving thrombolytic therapy and treated after non-ST segment infarction.Moreover,they report low control of their blood pressure(P=0.013)and less physical activity(P=0.001).Conclusion:The results of this study revealed that patients'treated with primary percutaneous coronary intervention had negative illness perception and limited behavioral changes 6 months after hospitalization in comparison with other treatment modalities such as percutaneous coronary intervention and thrombolytic treatment.Further research is recommended to confirm this association with longer follow-up study and among different cultures. 展开更多
关键词 Acute myocardial infarction Illness perception Primary percutaneous coronary intervention secondary prevention
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Knowledge, Attitudes and Perceptions of Secondary School Teenagers towards HIV Transmission and Prevention in Rural and Urban Areas of Central Uganda 被引量:1
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作者 Annamaria Rukundo Mathias M. Muwonge +3 位作者 Danny Mugisha Dickens Aturwanaho Arabat Kasangaki Godfrey S. Bbosa 《Health》 CAS 2016年第10期937-952,共16页
HIV/AIDS has remained a challenge in Uganda among adolescent despite the ABC strategy used globally to prevent HIV infection. The study assessed the knowledge, attitudes and perceptions of secondary school teenagers t... HIV/AIDS has remained a challenge in Uganda among adolescent despite the ABC strategy used globally to prevent HIV infection. The study assessed the knowledge, attitudes and perceptions of secondary school teenagers towards HIV transmission and prevention in rural and urban schools of central Uganda. A cross sectional study using self-administered questionnaires and structured interviews was used to collect data from adolescents in secondary schools in Kampala and Buikwe districts. Eight schools were randomly selected with 4 schools in each district. A total of 245 students from schools were recruited in the study with 120 and 125 students from urban Kampala and rural Buikwe district schools respectively. Data were analyzed using SPSS version 11. The results were expressed as percentages in a 2 × 2 tables. The mean age of the participants was 15.9 ± 2.5 years. Results showed that 95.1% participants had knowledge on HIV/AIDS in both urban and rural schools and 27.4% knew all the modes of HIV transmission. About 83.7% knew the ABC strategy for HIV prevention and 37.6% would talk about HIV/AIDS mainly with friends. For HIV cure, 62.0% of study participants reported non-cure and 24.9% were not sure. The remaining 13.1% of the study participants in both urban and rural schools reported that HIV can be cured. And the modes of curing HIV that were mentioned by participants included spiritual healing, transmitting it to others through sexual intercourse and that antiretroviral (ARVs) drugs can cure it as well as that it can be cured abroad. About 65.7% of participants reported recognition of one with HIV/ AIDS and by having red lips, being sickly;weight loss, skin rash and being very rich were mentioned. About 39.2% of the study participants mentioned that they cannot get infected with HIV and can’t contract HIV at all and 18.4% believed that chances of getting HIV infection were high. On perception and attitude on condoms and their use, participants reported that it is a sign of mistrust, reduces sexual pleasures and they are embarrassing to buy. Majority of the participants in both urban and rural schools had some knowledge on HIV/AIDS and the ABC strategy for HIV prevention. However, there was a knowledge gap on the various modes of HIV transmission and prevention. There was misconception of the participants on HIV/AIDS cure, condom use and on the chances of contracting HIV. About the source of HIV/AIDS information, majority of the participants were getting information on HIV/AIDS from friends of which some information was misleading. This false information could be the reason for the increased HIV prevalence reported among the adolescents in the schools. Generally, participants had some knowledge on HIV/AIDS though they had knowledge gap on HIV transmission and prevention. 展开更多
关键词 KNOWLEDGE ATTITUDES PERCEPTIONS HIV Transmission & prevention secondary School Teenagers
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Antiplatelet Therapy in the Secondary Prevention of Stroke 被引量:2
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作者 Graeme J. Hankey 《中国循证医学杂志》 CSCD 2004年第3期150-156,共7页
关键词 抗血小板治疗 急性缺血性脑卒中 预防 复发 血管疾病
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Social Cultural and Economic Factors Affecting the Practice of Secondary Prevention among Patients with Type 2 Diabetes Mellitus at Consolata Nkubu and Meru Level Five Hospital in Meru County
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作者 Dennis Mugambi Ngari Annastacia Munzi Mbisi Teresia Wanjiru Njogu 《Open Journal of Clinical Diagnostics》 2020年第1期1-17,共17页
Diabetes is chronic metabolic disorder characterized by states of hyperglycemia with disturbances of carbohydrates, fat and protein metabolism. Diabetes affects millions of people globally every day and the prevalence... Diabetes is chronic metabolic disorder characterized by states of hyperglycemia with disturbances of carbohydrates, fat and protein metabolism. Diabetes affects millions of people globally every day and the prevalence of the disease is on the rise due to unhealthy diet and lifestyle. The disorder usually results to chronic complications including cardiovascular diseases, diabetic nephropathy, diabetic neuropathy, foot ulcers and diabetic eye diseases that are all preventable through secondary preventive measures. Once an individual has been diagnosed with T2DM, secondary preventive approaches are essential in preventing the occurrence of chronic complications. However, lack of awareness of these measures has been cited as the common reasons for the development of complications. The study aimed to assess the effect of social cultural and economic factors on the practice of secondary diabetes prevention among patients with Type 2 Diabetes Mellitus (T2DM) at Consolata Hospital Nkubu and Meru Level Five Hospital between March and April 2019. A descriptive correlational study design was adopted to collect data from 357 purposively sampled participants with T2DM using questionnaires and Focus Group Discussion Guide. Quantitative data were analyzed using SPSS version 25 at 95% confidence interval and a significance level p ≤ 0.05. Most respondents attended Meru Teaching and Referral Hospital. Majority of the respondents were aged between 40 - 60 years. Most respondents 31.6% had secondary level of education and majority 67% was employed. Concerning secondary prevention, majority did foot examination on every visit 70.6% and BP monitoring 69.5% while 56.5% did annual eye screening. Level of income, affordability of services, health insurance cover of the patients, monthly cost of DM management and traditional beliefs in managing DM all significantly influenced DM secondary prevention at a p value ≤ 0.05. The factors need to be addressed to reduce the global burden posed by the disease. 展开更多
关键词 Type 2 Diabetes MELLITUS secondary prevention Economic FACTORS CULTURAL FACTORS Chronic COMPLICATIONS
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Secondary Prevention Following Coronary Artery Bypass Surgery: A Pilot Study for Improved Patient Education
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作者 Jeffrey B. Kramer Patricia A. Howard +8 位作者 Brian J. Barnes Bashar Ababneh Purna Mukhopadhyay Mazda Biria Gregory F. Muehlebach Emmanuel Daon George L. Zorn William A. Reed James L. Vacek 《International Journal of Clinical Medicine》 2012年第4期286-294,共9页
Background: Sustained positive outcomes after coronary artery bypass grafting (CABG) requires risk factor modification and secondary prevention medications. Much attention has been focused on planning at hospital disc... Background: Sustained positive outcomes after coronary artery bypass grafting (CABG) requires risk factor modification and secondary prevention medications. Much attention has been focused on planning at hospital discharge;however longer-term patient compliance is not well described. Hypothesis: A follow-up multidisciplinary educational program improves disease understanding, motivation to reduce cardiovascular risk, and secondary prevention medication prescribing following hospital discharge. Methods: Using a prospective, randomized, controlled design, patients undergoing CABG completed surveys over a year period, assessing disease understanding and motivation. Four to six weeks after CABG, intervention subjects completed a one-time educational program with a multidisciplinary team. The primary endpoint was a composite score of reduced risk factors, medication use, and awareness of prescribed medications. Secondary endpoints evaluated survey scores and medication use rates. Wilcoxon Rank Sum and Chi Square tests compared data between specific time points. Generalized estimating equations and linear contrasts of the parameter estimates compared data at the three time points. Results: The final analysis included 98 subjects (Intervention = 49, Control = 49). The composite score was not different between groups (I = 12.8 ± 4.5 points, C = 12.7 ± 4.9 points, p = 0.9405). Improvements were noted in understanding and motivation in the entire cohort, but these changes were not influenced by the intervention. Medication prescribing declined at 3 and 12 months after CABG without significant differences between the groups. Conclusions: Disease understanding, motivation to reduce risk, and medication use are robust at hospital discharge but the latter declines with time and was not improved by our intervention. These findings are concerning and warrant further study. 展开更多
关键词 secondary prevention CORONARY ARTERY Disease CORONARY ARTERY BYPASS
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Secondary prevention of ischaemic stroke
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作者 Irene Volonghi Alessandro Padovani +5 位作者 Elisabetta Del Zotto Alessia Giossi Paolo Costa Andrea Morotti Loris Poli Alessandro Pezzini 《World Journal of Neurology》 2013年第4期97-114,共18页
In spite of a documented reduction in incidence in highincome countries over the last decades, stroke is still a leading cause of death and disability worldwide. With the ageing of the population stroke-related econom... In spite of a documented reduction in incidence in highincome countries over the last decades, stroke is still a leading cause of death and disability worldwide. With the ageing of the population stroke-related economic burden is expected to increase, because of residual disability and its complications, such as cognitive impairment, high risk of falls and fractures, depression and epilepsy. Furthermore, because of the substantial rate of early and long-term vascular recurrences after the first event, secondary prevention after cerebral ischaemia is a crucial issue. This is even more important after minor stroke and transient ischaemic attack(TIA), in order to reduce the risk of potentially more severe and disabling events. To accomplish this aim, acute long-term medical and surgical treatments as well aslifestyle modifications are strongly recommended. However, apart from the well-established indications to thrombolysis, studies in acute phase after a first stroke or TIA are scarce and evidence is lacking. More trials are available for long-term secondary prevention with different classes of drugs, including antithrombotic medications for ischaemic events of arterial and cardiac origin, especially related to atrial fibrillation(antiplatelets and anticoagulants, respectively), lipid lowering agents(mainly statins), blood pressure lowering drugs, surgical and endovascular revascularization procedures. 展开更多
关键词 STROKE Transient ISCHAEMIC attack secondary prevention ANTIPLATELETS ANTICOAGULANTS Medical STROKE treatment CAROTID STENOSIS
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A Commentary on the Chinese Coronary Secondary Prevention Study
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作者 陆宗良 《Chinese Journal of Integrated Traditional and Western Medicine》 2006年第2期85-87,共3页
Chinese coronary secondary prevention study (CCSPS) is a key project in the field of medicine of the Ninth Five-year Plan of China, and is also called the Study of Xuezhikang Capsule (血脂康胶囊, XZK)in regulating... Chinese coronary secondary prevention study (CCSPS) is a key project in the field of medicine of the Ninth Five-year Plan of China, and is also called the Study of Xuezhikang Capsule (血脂康胶囊, XZK)in regulating blood lipids for secondary prevention of coronary heart diseases .Since the results of the study was publicized in June 2004 at the news release and deliberation by experts took place in the Great Hall of the People in Beijing, wide attention and high opinions have been gotten, and at the same time, 展开更多
关键词 FIGURE LDL A Commentary on the Chinese Coronary secondary prevention Study
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Exploring the Role of Nutraceuticals (Red Yeast Rice) in Secondary Prevention: A New Pathway Can Be Opened
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作者 Santiago de Dios Eduardo Fernandez Carrion +4 位作者 Javier Antona Makoshi Juan Jose Parra Fuertes Hector Fleites Eduardo Zatarain Jose Luis Zamorano Gomez 《World Journal of Cardiovascular Diseases》 2022年第1期24-29,共6页
<strong>Background:</strong><span style="white-space:normal;font-family:;" "=""> Long</span><span style="white-space:normal;font-family:;" "=&quo... <strong>Background:</strong><span style="white-space:normal;font-family:;" "=""> Long</span><span style="white-space:normal;font-family:;" "="">-</span><span style="white-space:normal;font-family:;" "="">term survival in acute coronary syndrome has increased steadily in the last decades. Follow-up studies developed in this patient clearly reveal that they are at risk of suffering a new event, placing them in a new stage, secondary prevention. Assuming this increased risk, the control target of their cardiovascular risk factors become more ambitious. In this field, control of Cholesterol levels, particularly LDL-C, ha</span><span style="white-space:normal;font-family:;" "="">s</span><span style="white-space:normal;font-family:;" "=""> arisen as a priority objective in patients with coronary arterial disease. In this sense, management of </span><span style="white-space:normal;font-family:;" "="">dyslipidemia </span><span style="white-space:normal;font-family:;" "="">guidelines, recently recognise</span><span style="white-space:normal;font-family:;" "="">s</span><span style="white-space:normal;font-family:;" "=""> the role of functional food, highlighting among them </span><span style="white-space:normal;font-family:;" "="">is </span><span style="white-space:normal;font-family:;" "="">the Red Yeast Rice (RYR). The aim of the study is to establish the potential role of functional food, in secondary prevention</span><span style="white-space:normal;font-family:;" "="">,</span><span style="white-space:normal;font-family:;" "=""> while deter</span><span style="white-space:normal;font-family:;" "="">mining its additional capacity to reduce LDL-C in patients that despite optimal classic treatment (maximum tolerated dose of stain plus Ezetimibe) </span><span style="white-space:normal;font-family:;" "="">is</span><span style="white-space:normal;font-family:;" "=""> still out of control objectives. <b>Results and Discussion:</b> 88 patients were included and after 3 months of treatment with RYR, their lipid profiles were compared with the baseline. The variation of T-Col, LDL-C and Trig were statistically significant. A reduction in LDL-C was 10.73</span><span style="white-space:normal;font-family:;" "=""> </span><span style="white-space:normal;font-family:;" "="">mg/dL, which means a 10.93% of additional reduction over the standard therapy the patients were receiving. Concerning security, no relevant side effects were reported when adding RYR, even in a relevant percentage (35.4%)</span><span style="white-space:normal;font-family:;" "="">,</span><span style="white-space:normal;font-family:;" "=""> myalgia disappeared (especially when reduc</span><span style="white-space:normal;font-family:;" "="">ing the </span><span style="white-space:normal;font-family:;" "="">titrating dose </span><span style="white-space:normal;font-family:;" "="">of </span><span style="white-space:normal;font-family:;" "="">the statin). <b>Conclusion:</b> Adding</span><span style="white-space:normal;font-family:;" "=""> RYR in secondary prevention patients in combination with the usual treatment, seems </span><span style="white-space:normal;font-family:;" "="">to be </span><span style="white-space:normal;font-family:;" "="">an effective alternative to optimi</span><span style="white-space:normal;font-family:;" "="">z</span><span style="white-space:normal;font-family:;" "="">e LDL levels and thus get</span><span style="white-space:normal;font-family:;" "="">s</span><span style="white-space:normal;font-family:;" "=""> closer to the target set in the</span><span style="white-space:normal;font-family:;" "=""> </span><span style="white-space:normal;font-family:;" "="">guidelines, without adding relevant side effects, </span><span style="white-space:normal;font-family:;" "="">and </span><span style="white-space:normal;font-family:;" "="">even improving tolerance to the statins.</span> 展开更多
关键词 LIPIDS NUTRACEUTICALS Coronary Artery Disease secondary prevention
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Quality evaluation and content analysis of non-drug guidelines on risk factors of secondary prevention of myocardial infarction
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作者 Wen-Jiao Li Meng-Zhu Zhao +4 位作者 Chang Rao Xue-Chao Liu Qi Liu Chang-De Jin Yan Li 《TMR Non-Drug Therapy》 2019年第4期127-135,共9页
Purpose: To strictly evaluate the quality of guidelines on risk factors related to secondaryprevention of myocardial infarction (MI), and to summarize and analyze the relevantrecommendations, and to provide evidence-b... Purpose: To strictly evaluate the quality of guidelines on risk factors related to secondaryprevention of myocardial infarction (MI), and to summarize and analyze the relevantrecommendations, and to provide evidence-based support for medical staff to developinterventions related risk factors for MI patients. Methods: The professional guideline websitesand databases in English and Chinese were retrieved, and the references related guidelines weretraced to get the published guidelines. Appraisal of Guidelines for Research and Evaluation IIwas used to evaluate the methodological quality of the guidelines. Then the relevantrecommendations for MI were summarized and analyzed. Results: A total of 8 guidelines,including evidence-based guidelines and expert consensus were included in the initial review of2,099 articles, among which 2 from the UK, 1 from the US and 5 from China. The overallquality of the included guidelines is moderate. However, some guidelines score relatively lowin the dimensions of rigor of development, clarity of presentations and editorial independence.A total of 24 items were extracted, including three risk factors: blood pressure, blood sugar andblood lipid. The recommendations mainly cover the relevant target values of risk factors,providing evidence-based support for medical staff to control and guide the risk factors ofpatients with MI in three aspects, such as blood pressure, blood sugar and blood lipid, whichproviding the theory basis for self-monitoring. Conclusions: It is recommended that clinicalpractice on risk factors of MI should be based on best evidence and fully put the individualfactors into account. 展开更多
关键词 Myocardial INFARCTION GUIDELINE Quality EVALUATION APPRAISAL of GUIDELINES forResearch and EVALUATION II secondary prevention
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Function of health education on secondary prevention of coronary heart disease
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作者 李海梅 《中国组织工程研究与临床康复》 CAS CSCD 2001年第19期154-,共1页
关键词 Function of health education on secondary prevention of coronary heart disease
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Meta-Analysis of Aspirin for Primary Prevention of Stroke
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作者 Panpan Zheng Yanjun Mao +2 位作者 Xiaoxia Yan Junrong Ding Yongsheng Ou 《Yangtze Medicine》 2022年第2期41-55,共15页
Objective: This paper aims to evaluate the safety and efficacy of aspirin in primary stroke prevention by meta-analysis. Methods: By searching PubMed, Cochrane Library, Embase, MEDLINE, Web of Science, CNKI, China Bio... Objective: This paper aims to evaluate the safety and efficacy of aspirin in primary stroke prevention by meta-analysis. Methods: By searching PubMed, Cochrane Library, Embase, MEDLINE, Web of Science, CNKI, China Biomedical Literature Database, VIP Database and Wanfang Database, we collected randomized controlled trials on aspirin for primary prevention of stroke. The retrieval time limit is from the establishment of the database to December 2021. Two researchers independently conducted literature search, screening, data extraction and quality evaluation, and Meta-analysis was performed using RevMan 5.3. Results: A total of 19 articles were included, including 220,636 subjects. Meta-analysis results show that long-term preventive use of aspirin can reduce the incidence of stroke [RR = 0.91, 95% CI (0.85, 0.98), P = 0.009], and reduce the incidence of ischemic stroke [RR = 0.84, 95% CI] (0.77, 0.91), P RR = 0.80, 95% CI (0.72, 0.88), P RR = 0.85, 95% CI (0.75, 0.97), P RR = 1.23, 95% CI (1.04, 1.46), P = 0.01] and gastrointestinal bleeding [RR = 1.62, 95% CI (1.35, 1.93), P RR = 0.97, 95% CI (0.93, 1.02), P = 0.20]. Conclusion: Long-term prophylactic use of aspirin can reduce the overall incidence of stroke, but there is also a risk of bleeding. The advantages and disadvantages of aspirin should be fully evaluated and strict screening should be carried out before medication, which can minimize adverse reactions and improve the safety and effectiveness of aspirin in the primary prevention of stroke. 展开更多
关键词 aspirin STROKE Primary prevention META-ANALYSIS
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社区规范管理稳定性冠心病患者运动耐量情况及其影响因素分析 被引量:2
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作者 杨玲 杜雪平 +1 位作者 董建琴 董玉明 《中国全科医学》 北大核心 2024年第1期51-58,共8页
背景稳定性冠心病(SCAD)患者冠状动脉硬化狭窄、斑块破裂形成血栓的风险高,再发心血管事件概率高,是反复住院的重要原因。发达国家通过运动康复为主的心脏康复使得本国心血管疾病的发生率、死亡率、再入院率明显下降,医疗费用降低。目... 背景稳定性冠心病(SCAD)患者冠状动脉硬化狭窄、斑块破裂形成血栓的风险高,再发心血管事件概率高,是反复住院的重要原因。发达国家通过运动康复为主的心脏康复使得本国心血管疾病的发生率、死亡率、再入院率明显下降,医疗费用降低。目的调查首都医科大学附属复兴医院月坛社区卫生服务中心规范管理SCAD患者运动耐量及其影响因素,为后期社区心脏康复提供科学依据。方法2020年1月,通过整群抽样在首都医科大学附属复兴医院月坛社区卫生服务中心卫生信息系统(CHIS)(医生工作站)选取规范管理、75岁以下SCAD患者980例,采用自行设计问卷[包括一般资料调查表、退伍军人特定活动问卷(VSAQ)等]对其进行调查。依据VSAQ测得的代谢当量(METs)值者分为运动耐量≤7.0 METs组和运动耐量>7.0 METs组,比较不同运动耐量SCAD患者临床资料的差异,采用Logistic回归分析探讨SCAD患者运动耐量的影响因素。结果980例SCAD患者中,运动耐量>7.0 METs者108例(11.0%),5.0~7.0 METs者619例(63.2%),<5.0 METs者253例(25.8%);运动耐量≤7.0METs组SCAD患者的性别、年龄、PCI术接受情况、糖尿病患病情况、血压达标情况、规律运动情况、运动强度水平、每次运动时间与运动耐量>7.0 METs组比较,差异有统计学意义(P<0.05)。Logistic回归分析结果显示,性别、年龄、是否患有糖尿病、血压控制是否达标、是否规律运动、运动强度是SCAD患者运动耐量的影响因素(P<0.05)。结论SCAD患者有运动意识,但运动耐量整体水平较低(≤7.0 METs),缺乏运动指导,建议通过运动康复,提高运动耐量,从而改善其生活质量。 展开更多
关键词 稳定性冠心病 二级预防 运动耐量 运动康复 影响因素分析
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中小学生心理健康问题家校协同预防的现状及对策 被引量:2
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作者 戴斌荣 杜思佳 +1 位作者 邱慧燕 申宏浩 《教育理论与实践》 北大核心 2024年第10期23-29,共7页
采用自编的《中小学生心理健康问题家校协同预防调查问卷》,对江苏省、河南省以及新疆维吾尔自治区41所中小学的3839名学生家长和1144名教师进行问卷调查,结果发现:家长和教师对学生心理健康问题家校协同预防责任的看法不够全面;家长和... 采用自编的《中小学生心理健康问题家校协同预防调查问卷》,对江苏省、河南省以及新疆维吾尔自治区41所中小学的3839名学生家长和1144名教师进行问卷调查,结果发现:家长和教师对学生心理健康问题家校协同预防责任的看法不够全面;家长和教师对学生心理健康问题家校协同预防方式比较单一;家长和教师参与学生心理健康问题家校协同预防程度不够;家长和教师对学生心理健康问题家校协同预防成效不够满意;影响学生心理健康问题家校协同预防成效的家长和教师因素是多方面的,能力有限是首选因素。提高中小学生心理健康问题家校协同预防成效,应形成家校协同预防共识,提升家校协同预防能力,强化家校协同预防保障机制。 展开更多
关键词 中小学生 心理健康问题 家校协同预防 预防共识 预防能力 预防保障机制
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