A simple stepwise folding process has been developed to simulate RNA secondary structure formation.Modifications for the energy parameters of various loops were included in the program.Five possible types of pseudokno...A simple stepwise folding process has been developed to simulate RNA secondary structure formation.Modifications for the energy parameters of various loops were included in the program.Five possible types of pseudoknots including the well known H-type pseudoknot were permitted to occur if reasonable.We have applied this approach to e number of RNA sequences.The prediction accuracies we obtained were higher than those in published papers.展开更多
文摘A simple stepwise folding process has been developed to simulate RNA secondary structure formation.Modifications for the energy parameters of various loops were included in the program.Five possible types of pseudoknots including the well known H-type pseudoknot were permitted to occur if reasonable.We have applied this approach to e number of RNA sequences.The prediction accuracies we obtained were higher than those in published papers.