A one metabolic-equivalent-of-task increase in peak aerobic fitness(peak MET)is associated with a clinically relevant improvement in survival risk and all-cause mortality.The co-dependent impact of free-living physica...A one metabolic-equivalent-of-task increase in peak aerobic fitness(peak MET)is associated with a clinically relevant improvement in survival risk and all-cause mortality.The co-dependent impact of free-living physical behaviours on aerobic fitness are poorly understood.The purpose of this study was to investigate the impact of theoretically re-allocating time spent in physical behaviours on aerobic fitness.We hypothesized that substituting sedentary time with any physical activity(at any intensity)would be associated with a predicted improvement in aerobic fitness.Peak volume rate of oxygen uptake(VO_(2)peak)was assessed via indirect calorimetry during a progressive,maximal cycle ergometer protocol in 103 adults(52 females;[38±21]years;[25.0±3.8]kg/m^(2);VO_(2)peak:[35.4±11.5]ml⋅kg^(-1)⋅min^(-1)).Habitual sedentary time,standing time,light-(LPA),moderate-(MPA),and vigorous-physical activity(VPA)were assessed 24-h/day via thigh-worn inclinometry for up to one week(average:[6.3±0.9]days).Isotemporal substitution modelling examined the impact of replacing one physical behaviour with another.Sedentary time(β=0.8,95%CI:[-1.3,-0.2])and standing time(β=0.9,95%CI:[-1.6,-0.2])were negatively associated with VO_(2)peak,whereas VPA was positively associated with relative VO_(2)peak(β=9.2,95%CI:[0.9,17.6]).Substituting 30-min/day of VPA with any other behaviour was associated with a 2.4–3.4 higher peak MET.Higher standing time was associated with a lower aerobic fitness.As little as 10-min/day of VPA predicted a clinically relevant 0.8–1.1 peak MET increase.Theoretically,replacing any time with relatively small amounts of VPA is associated with improvements in aerobic fitness.展开更多
文摘A one metabolic-equivalent-of-task increase in peak aerobic fitness(peak MET)is associated with a clinically relevant improvement in survival risk and all-cause mortality.The co-dependent impact of free-living physical behaviours on aerobic fitness are poorly understood.The purpose of this study was to investigate the impact of theoretically re-allocating time spent in physical behaviours on aerobic fitness.We hypothesized that substituting sedentary time with any physical activity(at any intensity)would be associated with a predicted improvement in aerobic fitness.Peak volume rate of oxygen uptake(VO_(2)peak)was assessed via indirect calorimetry during a progressive,maximal cycle ergometer protocol in 103 adults(52 females;[38±21]years;[25.0±3.8]kg/m^(2);VO_(2)peak:[35.4±11.5]ml⋅kg^(-1)⋅min^(-1)).Habitual sedentary time,standing time,light-(LPA),moderate-(MPA),and vigorous-physical activity(VPA)were assessed 24-h/day via thigh-worn inclinometry for up to one week(average:[6.3±0.9]days).Isotemporal substitution modelling examined the impact of replacing one physical behaviour with another.Sedentary time(β=0.8,95%CI:[-1.3,-0.2])and standing time(β=0.9,95%CI:[-1.6,-0.2])were negatively associated with VO_(2)peak,whereas VPA was positively associated with relative VO_(2)peak(β=9.2,95%CI:[0.9,17.6]).Substituting 30-min/day of VPA with any other behaviour was associated with a 2.4–3.4 higher peak MET.Higher standing time was associated with a lower aerobic fitness.As little as 10-min/day of VPA predicted a clinically relevant 0.8–1.1 peak MET increase.Theoretically,replacing any time with relatively small amounts of VPA is associated with improvements in aerobic fitness.
