Objective:To investigate the clinical diagnostic significance of peripheral blood T-cell test(T-spot test)for tuberculosis(TB)infection combined with erythrocyte sedimentation rate(ESR)in pulmonary TB.Methods:41 patie...Objective:To investigate the clinical diagnostic significance of peripheral blood T-cell test(T-spot test)for tuberculosis(TB)infection combined with erythrocyte sedimentation rate(ESR)in pulmonary TB.Methods:41 patients with a clinical diagnosis of TB during hospitalization from January 2020 to April 2023 in our hospital were selected as the experimental group,and 45 patients without TB(bronchopneumonia patients)were selected as the control group.The diagnostic specificity,sensitivity,and accuracy of the T-spot TB test,ESR test,and the combined test of the two were calculated respectively.Results:The sensitivity,specificity,and accuracy of the T-spot TB test combined with ESR for the diagnosis of TB in the experimental group were significantly higher than the individual results of the T-spot TB test and ESR test alone(P<0.05).Conclusion:The T-spot TB test combined with the ESR test for TB diagnosis has greater clinical value than carrying out the tests individually.展开更多
In marine engineering, the strength of a submarine sediment is an indispensable parameter for assessment of construction. In this study, a free-fall cone penetrator named IPen was developed to realize a rapid and effi...In marine engineering, the strength of a submarine sediment is an indispensable parameter for assessment of construction. In this study, a free-fall cone penetrator named IPen was developed to realize a rapid and efficient measurement of sediment strength. The equipment is characterized by modular design and self-contained data acquisition. It is equipped with an acceleration sensor, a water pressure sensor, and a piezocone penetration test(CPTu) probe. It is designed to be released from near seabed surface with a releaser and then fall freely to provide a higher penetration velocity. Its maximum working depth is approximately 2500 m and maximum penetration depth is approximately 3 m. To derive the correlation between penetration resistance and sediment strength, a calibrator was devised to determine the penetration-rate factor. In addition, the factor applicable to in situ test points was determined in laboratory experiments. In June 2016, the IPen was tested in situ in the South Yellow Sea, China, during a shared voyage funded by the National Science Foundation. Meanwhile, undisturbed column samples were collected for laboratory tests. Based on the in situ test results, it was demonstrated that the IPen could accurately record the working states of various sensors during the freely falling course. IPen test results reliably reflected the sediment strength at all the testing points when compared with laboratory calibration tests, in situ vane tests and penetration tests, laboratory penetration tests, and unconsolidated and undrained triaxial compression tests.展开更多
Detrital white mica single\|crystal Ar\|Ar ages from the Himalayan foreland sedimentary record are potentially a powerful tool in constraining source regions, tectonic evolution, and the timing and extent of exhumatio...Detrital white mica single\|crystal Ar\|Ar ages from the Himalayan foreland sedimentary record are potentially a powerful tool in constraining source regions, tectonic evolution, and the timing and extent of exhumation (Copeland 1990, Najman 1997, White 1999). However such studies require large numbers of analyses, and Ar/Ar total\|fusion of white mica grains is a very rapid and cost\|effective technique.Such analyses, however, do result in the sacrifice of internal consistency checks inherent in, for example, Ar/Ar step\|heating analysis.展开更多
Mechanical properties of methane hydrate- bearing-sediments （MHBS） are basic parameters for safety analysis of hydrate exploration and exploitation. Young＇s modulus, cohesion, and internal friction angle of hydrate...Mechanical properties of methane hydrate- bearing-sediments （MHBS） are basic parameters for safety analysis of hydrate exploration and exploitation. Young＇s modulus, cohesion, and internal friction angle of hydrate- bearing sediments synthesized in laboratory, are investigated using tri-axial tests. Stress-strain curves and strength parameters are obtained and discussed for different compositions and different hydrate saturation, followed by empirical expressions related to the cohesion, internal friction angle, and modulus of MHBS. Almost all tested MHBS samples exhibit plastic failure. With the increase of total saturation of ice and methane hydrate （MH）, the specimens＇ internal friction angle decreases while the cohesion increases.展开更多
A triaxial system is designed with a temperature range from -20 ℃ to 25℃ and a pressure range from 0 MPa to 30 MPa in order to improve the understanding of the mechanical properties of gas hydrate-bearing sediments....A triaxial system is designed with a temperature range from -20 ℃ to 25℃ and a pressure range from 0 MPa to 30 MPa in order to improve the understanding of the mechanical properties of gas hydrate-bearing sediments. The mechanical properties of synthetic gas hydrate-bearing sediments （gas hydrate-kaolin clay mixture） were measured by using current experimental apparatus. The results indicate that： （1） the failure strength of gas hydrate-bearing sediments strongly depends on the temperature. The sediment＇s strength increases with the decreases of temperature. （2） The maximum deviator stress increases linearly with the confining pressure at a low-pressure stage. However, it fluctuates at a high-pressure stage. （3） Maximum deviator stress increases with increasing strain rate, whereas the strain-stress curve has no tremendous change until the axial strain reaches approximately 0.5%. （4） The internal friction angles of gas hydrate-bearing sediments are not sensitive to kaolin volume ratio. The cohesion shows a high kaolin volume ratio dependency.展开更多
The complex distribution of gas hydrate in sediments makes understanding the mechanical properties of hydrate-bearing sediments a challenging task.The mechanical behaviors of hydrate-bearing interlayered sediments are...The complex distribution of gas hydrate in sediments makes understanding the mechanical properties of hydrate-bearing sediments a challenging task.The mechanical behaviors of hydrate-bearing interlayered sediments are still poorly known.A series of triaxial shearing tests were conducted to investigate the strength parameters and deformation properties of methane hydrate-bearing interlayered sediments at the effective pressure of 1 MPa.The results indicate that the stress-strain curves of hydrate-bearing interlayered sediments are significantly different from that of hydrate-bearing sediments.The peak strength,Young's modulus,initial yielding modulus,and failure mode are deeply affected by the methane hydrate distribution.The failure behaviors and mechanism of strain softening and hardening patterns of the interlayered specimens are more complicated than those of the integrated specimens.This study compares the different mechanical behaviors between integrated and interlayered specimens containing gas hydrate,which can serve as a reference for the prediction and analysis of the deformation behaviors of natural gas hydrate reservoirs.展开更多
文摘Objective:To investigate the clinical diagnostic significance of peripheral blood T-cell test(T-spot test)for tuberculosis(TB)infection combined with erythrocyte sedimentation rate(ESR)in pulmonary TB.Methods:41 patients with a clinical diagnosis of TB during hospitalization from January 2020 to April 2023 in our hospital were selected as the experimental group,and 45 patients without TB(bronchopneumonia patients)were selected as the control group.The diagnostic specificity,sensitivity,and accuracy of the T-spot TB test,ESR test,and the combined test of the two were calculated respectively.Results:The sensitivity,specificity,and accuracy of the T-spot TB test combined with ESR for the diagnosis of TB in the experimental group were significantly higher than the individual results of the T-spot TB test and ESR test alone(P<0.05).Conclusion:The T-spot TB test combined with the ESR test for TB diagnosis has greater clinical value than carrying out the tests individually.
基金funded by the National Natural Science Foundation of China (Nos. 41502265 and 41427803)the Key Research and Development Program of Shandong Province, China (No. 2016ZDJS09A03)+1 种基金Data acquisition and sample collections were supported by NSFC Open Research Cruise (Cruise Nos. NORC2016-01 and NORC2017-05)funded by Shiptime Sharing Project of NSFC
文摘In marine engineering, the strength of a submarine sediment is an indispensable parameter for assessment of construction. In this study, a free-fall cone penetrator named IPen was developed to realize a rapid and efficient measurement of sediment strength. The equipment is characterized by modular design and self-contained data acquisition. It is equipped with an acceleration sensor, a water pressure sensor, and a piezocone penetration test(CPTu) probe. It is designed to be released from near seabed surface with a releaser and then fall freely to provide a higher penetration velocity. Its maximum working depth is approximately 2500 m and maximum penetration depth is approximately 3 m. To derive the correlation between penetration resistance and sediment strength, a calibrator was devised to determine the penetration-rate factor. In addition, the factor applicable to in situ test points was determined in laboratory experiments. In June 2016, the IPen was tested in situ in the South Yellow Sea, China, during a shared voyage funded by the National Science Foundation. Meanwhile, undisturbed column samples were collected for laboratory tests. Based on the in situ test results, it was demonstrated that the IPen could accurately record the working states of various sensors during the freely falling course. IPen test results reliably reflected the sediment strength at all the testing points when compared with laboratory calibration tests, in situ vane tests and penetration tests, laboratory penetration tests, and unconsolidated and undrained triaxial compression tests.
文摘Detrital white mica single\|crystal Ar\|Ar ages from the Himalayan foreland sedimentary record are potentially a powerful tool in constraining source regions, tectonic evolution, and the timing and extent of exhumation (Copeland 1990, Najman 1997, White 1999). However such studies require large numbers of analyses, and Ar/Ar total\|fusion of white mica grains is a very rapid and cost\|effective technique.Such analyses, however, do result in the sacrifice of internal consistency checks inherent in, for example, Ar/Ar step\|heating analysis.
基金supported by the National Natural Science Foundation of China (11102209 and 11072245)the National High Technology Research and Development Program of China (863)the Key Program of Chinese Academy of Sciences (KJCX2-YW-L02)
文摘Mechanical properties of methane hydrate- bearing-sediments （MHBS） are basic parameters for safety analysis of hydrate exploration and exploitation. Young＇s modulus, cohesion, and internal friction angle of hydrate- bearing sediments synthesized in laboratory, are investigated using tri-axial tests. Stress-strain curves and strength parameters are obtained and discussed for different compositions and different hydrate saturation, followed by empirical expressions related to the cohesion, internal friction angle, and modulus of MHBS. Almost all tested MHBS samples exhibit plastic failure. With the increase of total saturation of ice and methane hydrate （MH）, the specimens＇ internal friction angle decreases while the cohesion increases.
基金supported by the National High Technology Research and Development Program of China(863 Program,Grant No. 2006AA09A209)the Major National S&T Program(Grant No. 2008ZX05026-004)+1 种基金the Major State Basic Research Development Program of China(973 Program,Grant No. 2009CB219507)the National Natural Science Foundation of China(Grant No.91010015)
文摘A triaxial system is designed with a temperature range from -20 ℃ to 25℃ and a pressure range from 0 MPa to 30 MPa in order to improve the understanding of the mechanical properties of gas hydrate-bearing sediments. The mechanical properties of synthetic gas hydrate-bearing sediments （gas hydrate-kaolin clay mixture） were measured by using current experimental apparatus. The results indicate that： （1） the failure strength of gas hydrate-bearing sediments strongly depends on the temperature. The sediment＇s strength increases with the decreases of temperature. （2） The maximum deviator stress increases linearly with the confining pressure at a low-pressure stage. However, it fluctuates at a high-pressure stage. （3） Maximum deviator stress increases with increasing strain rate, whereas the strain-stress curve has no tremendous change until the axial strain reaches approximately 0.5%. （4） The internal friction angles of gas hydrate-bearing sediments are not sensitive to kaolin volume ratio. The cohesion shows a high kaolin volume ratio dependency.
基金supported by the National Natural Science Foundation of China (No. 41976074)National Key Research and Development Plan (No. 2017YFC030 7600)+2 种基金the Taishan Scholar Special Experts Project (No. ts201712079)Qingdao National Laboratory for Marine Science and Technology (No. QNLM2016ORP0207)the Graduate School Innovation Program of China University of Petroleum (East China) (No. YCX2019020)
文摘The complex distribution of gas hydrate in sediments makes understanding the mechanical properties of hydrate-bearing sediments a challenging task.The mechanical behaviors of hydrate-bearing interlayered sediments are still poorly known.A series of triaxial shearing tests were conducted to investigate the strength parameters and deformation properties of methane hydrate-bearing interlayered sediments at the effective pressure of 1 MPa.The results indicate that the stress-strain curves of hydrate-bearing interlayered sediments are significantly different from that of hydrate-bearing sediments.The peak strength,Young's modulus,initial yielding modulus,and failure mode are deeply affected by the methane hydrate distribution.The failure behaviors and mechanism of strain softening and hardening patterns of the interlayered specimens are more complicated than those of the integrated specimens.This study compares the different mechanical behaviors between integrated and interlayered specimens containing gas hydrate,which can serve as a reference for the prediction and analysis of the deformation behaviors of natural gas hydrate reservoirs.
