Investigation of the Clinical Diagnostic Significance of the T-Cell Test for Tuberculosis combined with Erythrocyte Sedimentation Test in Pulmonary Tuberculosis

Objective:To investigate the clinical diagnostic significance of peripheral blood T-cell test(T-spot test)for tuberculosis(TB)infection combined with erythrocyte sedimentation rate(ESR)in pulmonary TB.Methods:41 patients with a clinical diagnosis of TB during hospitalization from January 2020 to April 2023 in our hospital were selected as the experimental group,and 45 patients without TB(bronchopneumonia patients)were selected as the control group.The diagnostic specificity,sensitivity,and accuracy of the T-spot TB test,ESR test,and the combined test of the two were calculated respectively.Results:The sensitivity,specificity,and accuracy of the T-spot TB test combined with ESR for the diagnosis of TB in the experimental group were significantly higher than the individual results of the T-spot TB test and ESR test alone(P<0.05).Conclusion:The T-spot TB test combined with the ESR test for TB diagnosis has greater clinical value than carrying out the tests individually.

Experimental study on mechanical properties of methane-hydrate-bearing sediments

Mechanical properties of methane hydrate- bearing-sediments （MHBS） are basic parameters for safety analysis of hydrate exploration and exploitation. Young＇s modulus, cohesion, and internal friction angle of hydrate- bearing sediments synthesized in laboratory, are investigated using tri-axial tests. Stress-strain curves and strength parameters are obtained and discussed for different compositions and different hydrate saturation, followed by empirical expressions related to the cohesion, internal friction angle, and modulus of MHBS. Almost all tested MHBS samples exhibit plastic failure. With the increase of total saturation of ice and methane hydrate （MH）, the specimens＇ internal friction angle decreases while the cohesion increases.

Shear creep parameters of simulative soil for deep-sea sediment

Based on mineral component and in-situ vane shear strength of deep-sea sediment, four kinds of simulative soils were prepared by mixing different bentonites with water in order to find the best simulative soil for the deep-sea sediment collected from the Pacific C-C area. Shear creep characteristics of the simulative soil were studied by shear creep test and shear creep parameters were determined by Burgers creep model. Research results show that the shear creep curves of the simulative soil can be divided into transient creep, unstable creep and stable creep, where the unstable creep stage is very short due to its high water content. The shear creep parameters increase with compressive stress and change slightly or fluctuate to approach a constant value with shear stress, and thus average creep parameters under the same compressive stress are used as the creep parameters of the simulative soil. Traction of the deep-sea mining machine walking at a constant velocity can be calculated by the shear creep constitutive equation of the deep-sea simulative soil, which provides a theoretical basis for safe operation and optimal design of the deep-sea mining machine.