A novel porous lanthanide-organic coordination polymer, [Nd（H2O）（HnicO）（TP）]·2H2O （1） （H2nicO=2-hydroxynicotinic acid, TP= terephthalate）, was prepared under hydrothermal condition and characterized by ...A novel porous lanthanide-organic coordination polymer, [Nd（H2O）（HnicO）（TP）]·2H2O （1） （H2nicO=2-hydroxynicotinic acid, TP= terephthalate）, was prepared under hydrothermal condition and characterized by single-crystal X-ray diffraction, thermogravimetric analysis and infrared spectroscopy. Compound 1 exhibited a flexible coordination geometry of lanthanide ions, which possessed a three-dimensional （3D） open framework with one-dimensional （1D） channels containing lattice water molecules. This framework structure exhibited a high stability up to 330℃ after removing free water molecules. A homometallic supramolecular framework （Zn（HnicO）2（H2O）2 （2）） was obtained due to the competitive reaction between organic ligands, Nd3＋ and Zn2＋ ions. The results showed that on the basis of the soft-hard/acid-base principle the coordination selection between metal ions and organic ligands played an essential role in the smart construction of lanthanide architectures.展开更多
The reaction of the reduced Schiff base HL（N-（4-hydroxybenzyl）-L-serine） with Zn（CH3COO）2·2H2O in aqueous solution afforded [Zn（L）2]·3H2O（I）. The complex has been characterized by elemental analysi...The reaction of the reduced Schiff base HL（N-（4-hydroxybenzyl）-L-serine） with Zn（CH3COO）2·2H2O in aqueous solution afforded [Zn（L）2]·3H2O（I）. The complex has been characterized by elemental analysis, FT-IR, powder X-ray diffraction, electrospray ionization mass spectrometry and single-crystal X-ray diffraction. Complex I crystallizes in the orthorhombic system, space group P212121, with a=9.197（2）, b=10.445（2）, c=24.149（5） , V=2319.8（8） 3, Z=4, C（20）H（30）N2O11 Zn, Mr=539.83, Dc=1.546 g·cm3, μ=1.122 mm（-1）, F（000）=1128, GOOF=0.971, the final R=0.0206 and w R=0.0506 for 4346 observed reflections（I ＆gt; 2σ（I））. In complex I, each Zn（II） ion coordinates with three carboxyl oxygen atoms and two amine nitrogen atoms from three L-anions, forming a distorted five-coordinated trigonal bipyramidal geometry. Complex I exhibits a 1D wavy chain structure that is extended by hydrogen-bonding interactions to form a supramolecular network. The bioactivity of the complex as a potential PTPs inhibitor in vitro was investigated, displaying potent inhibition against PTP1B（IC（50）, 0.24 μM） and TCPTP（IC（50）, 0.53 μM） with a moderate selectivity.展开更多
基金Program for New Century Excellent Talents in University (NCET-05-0278)the National Natural Science Foundation of China (50872016)the Foundation for the Author of National Excellent Doctoral Dissertation of China (200322)
文摘A novel porous lanthanide-organic coordination polymer, [Nd（H2O）（HnicO）（TP）]·2H2O （1） （H2nicO=2-hydroxynicotinic acid, TP= terephthalate）, was prepared under hydrothermal condition and characterized by single-crystal X-ray diffraction, thermogravimetric analysis and infrared spectroscopy. Compound 1 exhibited a flexible coordination geometry of lanthanide ions, which possessed a three-dimensional （3D） open framework with one-dimensional （1D） channels containing lattice water molecules. This framework structure exhibited a high stability up to 330℃ after removing free water molecules. A homometallic supramolecular framework （Zn（HnicO）2（H2O）2 （2）） was obtained due to the competitive reaction between organic ligands, Nd3＋ and Zn2＋ ions. The results showed that on the basis of the soft-hard/acid-base principle the coordination selection between metal ions and organic ligands played an essential role in the smart construction of lanthanide architectures.
基金Supported by NNSFC(Nos.21271121,21471092,21571118)
文摘The reaction of the reduced Schiff base HL（N-（4-hydroxybenzyl）-L-serine） with Zn（CH3COO）2·2H2O in aqueous solution afforded [Zn（L）2]·3H2O（I）. The complex has been characterized by elemental analysis, FT-IR, powder X-ray diffraction, electrospray ionization mass spectrometry and single-crystal X-ray diffraction. Complex I crystallizes in the orthorhombic system, space group P212121, with a=9.197（2）, b=10.445（2）, c=24.149（5） , V=2319.8（8） 3, Z=4, C（20）H（30）N2O11 Zn, Mr=539.83, Dc=1.546 g·cm3, μ=1.122 mm（-1）, F（000）=1128, GOOF=0.971, the final R=0.0206 and w R=0.0506 for 4346 observed reflections（I ＆gt; 2σ（I））. In complex I, each Zn（II） ion coordinates with three carboxyl oxygen atoms and two amine nitrogen atoms from three L-anions, forming a distorted five-coordinated trigonal bipyramidal geometry. Complex I exhibits a 1D wavy chain structure that is extended by hydrogen-bonding interactions to form a supramolecular network. The bioactivity of the complex as a potential PTPs inhibitor in vitro was investigated, displaying potent inhibition against PTP1B（IC（50）, 0.24 μM） and TCPTP（IC（50）, 0.53 μM） with a moderate selectivity.
