This paper describes the self—adjustment of some tuning-knobs of the generalized predictive controller(GPC).A three feedforward neural network was utilized to on line learn two key tuning-knobs of GPC,and BP algorith...This paper describes the self—adjustment of some tuning-knobs of the generalized predictive controller(GPC).A three feedforward neural network was utilized to on line learn two key tuning-knobs of GPC,and BP algorithm was used for the training of the linking-weights of the neural network.Hence it gets rid of the difficulty of choosing these tuning-knobs manually and provides easier condition for the wide applications of GPC on industrial plants.Simulation results illustrated the effectiveness of the method.展开更多
The relation between structures and properties of polyurethane are investigated by modern physical and chemical methods.The results obtained are as follows:the effects of the content of self-crosslinking agent on the ...The relation between structures and properties of polyurethane are investigated by modern physical and chemical methods.The results obtained are as follows:the effects of the content of self-crosslinking agent on the properties of polyurethane,i.e.,dispersion stability,dynamical viscoelasticity and mechanical properties are discussed.It is found that the optimum molar ratio of epichlorohydrin and diethylenetriamine is 1:2.A mois-展开更多
The Belt and Road Initiative contains the aspiration of Chinese nation to pursue ideological freedom and desire of strengthening international exchanges and cooperation. This paper takes the Belt and Road Initiative f...The Belt and Road Initiative contains the aspiration of Chinese nation to pursue ideological freedom and desire of strengthening international exchanges and cooperation. This paper takes the Belt and Road Initiative for example,emphasizing the interpretation of the inheritance and development of Chinese culture so as to study the importance of Culture Self-Consciousness in Chinese Philosophy,in the context of English globalization. That is to say,this paper stresses the spirits and the stand of nation 's demonstration on pursuing peace,cooperation and sustainable development in the civilization continuity from traditional China to the contemporary China,with practical philosophic view.展开更多
相较于传统药物的研发,药物-靶标的预测方法能够有效降低成本,加快研发进程,但是在实际应用中存在数据集平衡度低、预测精确率不高等问题。基于此,提出一种自适应球形演化的药物-靶标相互作用预测方法ASEKELM(self-Adaptive Spherical E...相较于传统药物的研发,药物-靶标的预测方法能够有效降低成本,加快研发进程,但是在实际应用中存在数据集平衡度低、预测精确率不高等问题。基于此,提出一种自适应球形演化的药物-靶标相互作用预测方法ASEKELM(self-Adaptive Spherical Evolution based on Kernel Extreme Learning Machine)。该方法根据结构相似的药物与靶标更易存在相互作用的原理筛选出高置信度的负样本;并且为了解决球形演化算法易陷入局部最优的问题,利用搜索因子历史记忆的反馈机制及群大小线性递减的策略(LPSR),实现全局搜索和局部搜索的平衡,提高算法的寻优能力;然后利用自适应球形演化算法对核极限学习机(KELM)的参数进行优化。在基于黄金标准的数据集上将ASEKELM与NetLapRLS(Network Laplacian Regularized Least Square)、BLM-NII(Bipartite Local Model with Neighbor-based Interaction profile Inferring)等算法进行对比,验证算法的性能。实验结果表明,在酶(E)、G-蛋白偶联受体(GPCR)、离子通道(IC)和核受体(NR)数据集中,ASE-KELM的ROC曲线下面积(AUC)与PR曲线下面积(AUPR)均优于对比算法;且基于DrugBank等数据库,ASE-KELM在预测新药物-靶标对的验证过程中表现良好。展开更多
We propose an integrative self-organizing map (iSOM) for exploring differential expression patterns across multiple microarray experiments. The algorithm is based on the assumption that observed differential expressio...We propose an integrative self-organizing map (iSOM) for exploring differential expression patterns across multiple microarray experiments. The algorithm is based on the assumption that observed differential expressions are random samples of a mean pattern model which is unknowna priori. The learning mechanism of iSOM is similar to the conventional SOM. The mean pattern model which underlies the proposed iSOM models mean differential expressions using a one-dimension of mean differential expressions for the mean differential expressions. The feature map of an iSOM model can be used to reveal correlation between multiple medically/biologically related disease types or multiple platform experiments for one disease. We illustrate applications of iSOM using simulated data and real data.展开更多
A new approach of detecting the black hole spin in x-ray binaries is proposed based on the model of the coexistence of the Blandford-Znajek （BZ） and magnetic coupling （MC） processes, in which the BZ process is use...A new approach of detecting the black hole spin in x-ray binaries is proposed based on the model of the coexistence of the Blandford-Znajek （BZ） and magnetic coupling （MC） processes, in which the BZ process is used to power the jet emissions from x-ray binaries, and high frequency quasi-periodic oscillations （QPOs） are explained by a rotating hotspot in the inner region of the accretion disc surrounding a fast-spinning black hole. It is shown that the black hole spins of several x-ray binaries （XTE J1550-564, GRO d1665-40 and GRS 1915＋105） can be constrained in a rather narrow range, provided that QPOs and jets coexist in these sources.展开更多
Structural choice is a significant decision having an important influence on structural function, social economics, structural reliability and construction cost. A Case Based Reasoning system with its retrieval part c...Structural choice is a significant decision having an important influence on structural function, social economics, structural reliability and construction cost. A Case Based Reasoning system with its retrieval part constructed with a KDD subsystem, is put forward to make a decision for a large scale engineering project. A typical CBR system consists of four parts: case representation, case retriever, evaluation, and adaptation. A case library is a set of parameterized excellent and successful structures. For a structural choice, the key point is that the system must be able to detect the pattern classes hidden in the case library and classify the input parameters into classes properly. That is done by using the KDD Data Mining algorithm based on Self Organizing Feature Maps (SOFM), which makes the whole system more adaptive, self organizing, self learning and open.展开更多
“Nothing can come of nothing”作为莎士比亚悲剧《李尔王》中的一句经典台词,深刻地绘就了早期李尔的精神底色。“无中不能生有”这个重要的哲学命题,自从被古希腊哲学家巴门尼德提出后,便为后世的西方哲学家所普遍讨论。在《李尔王...“Nothing can come of nothing”作为莎士比亚悲剧《李尔王》中的一句经典台词,深刻地绘就了早期李尔的精神底色。“无中不能生有”这个重要的哲学命题,自从被古希腊哲学家巴门尼德提出后,便为后世的西方哲学家所普遍讨论。在《李尔王》的英文原著中,“nothing”具有多元的内在含义。“有”与“没有”的讨论涉及了亲情、爱情多个方面,主人公观念中两者二元关系的转变也演绎着关于“真人”的成长故事。不论是对个体存在状态的呈现还是对人与自然动态关系的思考,《李尔王》都极具历史与现实两个维度的哲学价值。《李尔王》在双线索的交织中塑造出一众个性迥异而鲜明的人物形象,“有”与“没有”之间,暗含着“爱”的形式与本质之争,藏匿着“真人”成长蜕变的隐性轨迹。透过失势、战争、死亡、赎罪,我们思考生命存在的意义,审视社会关系的复杂,收获深沉的人性力量。展开更多
基金Supported by the National 863 CIMS Project Foundation(863-511-010)Tianjin Natural Science Foundation(983602011)Backbone Young Teacher Project Foundation of Ministry of Education
文摘This paper describes the self—adjustment of some tuning-knobs of the generalized predictive controller(GPC).A three feedforward neural network was utilized to on line learn two key tuning-knobs of GPC,and BP algorithm was used for the training of the linking-weights of the neural network.Hence it gets rid of the difficulty of choosing these tuning-knobs manually and provides easier condition for the wide applications of GPC on industrial plants.Simulation results illustrated the effectiveness of the method.
文摘The relation between structures and properties of polyurethane are investigated by modern physical and chemical methods.The results obtained are as follows:the effects of the content of self-crosslinking agent on the properties of polyurethane,i.e.,dispersion stability,dynamical viscoelasticity and mechanical properties are discussed.It is found that the optimum molar ratio of epichlorohydrin and diethylenetriamine is 1:2.A mois-
文摘The Belt and Road Initiative contains the aspiration of Chinese nation to pursue ideological freedom and desire of strengthening international exchanges and cooperation. This paper takes the Belt and Road Initiative for example,emphasizing the interpretation of the inheritance and development of Chinese culture so as to study the importance of Culture Self-Consciousness in Chinese Philosophy,in the context of English globalization. That is to say,this paper stresses the spirits and the stand of nation 's demonstration on pursuing peace,cooperation and sustainable development in the civilization continuity from traditional China to the contemporary China,with practical philosophic view.
文摘相较于传统药物的研发,药物-靶标的预测方法能够有效降低成本,加快研发进程,但是在实际应用中存在数据集平衡度低、预测精确率不高等问题。基于此,提出一种自适应球形演化的药物-靶标相互作用预测方法ASEKELM(self-Adaptive Spherical Evolution based on Kernel Extreme Learning Machine)。该方法根据结构相似的药物与靶标更易存在相互作用的原理筛选出高置信度的负样本;并且为了解决球形演化算法易陷入局部最优的问题,利用搜索因子历史记忆的反馈机制及群大小线性递减的策略(LPSR),实现全局搜索和局部搜索的平衡,提高算法的寻优能力;然后利用自适应球形演化算法对核极限学习机(KELM)的参数进行优化。在基于黄金标准的数据集上将ASEKELM与NetLapRLS(Network Laplacian Regularized Least Square)、BLM-NII(Bipartite Local Model with Neighbor-based Interaction profile Inferring)等算法进行对比,验证算法的性能。实验结果表明,在酶(E)、G-蛋白偶联受体(GPCR)、离子通道(IC)和核受体(NR)数据集中,ASE-KELM的ROC曲线下面积(AUC)与PR曲线下面积(AUPR)均优于对比算法;且基于DrugBank等数据库,ASE-KELM在预测新药物-靶标对的验证过程中表现良好。
文摘We propose an integrative self-organizing map (iSOM) for exploring differential expression patterns across multiple microarray experiments. The algorithm is based on the assumption that observed differential expressions are random samples of a mean pattern model which is unknowna priori. The learning mechanism of iSOM is similar to the conventional SOM. The mean pattern model which underlies the proposed iSOM models mean differential expressions using a one-dimension of mean differential expressions for the mean differential expressions. The feature map of an iSOM model can be used to reveal correlation between multiple medically/biologically related disease types or multiple platform experiments for one disease. We illustrate applications of iSOM using simulated data and real data.
基金Supported by the National Natural Science Foundation of China under Grant Nos 10173004, 10373006 and 10121503.
文摘A new approach of detecting the black hole spin in x-ray binaries is proposed based on the model of the coexistence of the Blandford-Znajek （BZ） and magnetic coupling （MC） processes, in which the BZ process is used to power the jet emissions from x-ray binaries, and high frequency quasi-periodic oscillations （QPOs） are explained by a rotating hotspot in the inner region of the accretion disc surrounding a fast-spinning black hole. It is shown that the black hole spins of several x-ray binaries （XTE J1550-564, GRO d1665-40 and GRS 1915＋105） can be constrained in a rather narrow range, provided that QPOs and jets coexist in these sources.
文摘Structural choice is a significant decision having an important influence on structural function, social economics, structural reliability and construction cost. A Case Based Reasoning system with its retrieval part constructed with a KDD subsystem, is put forward to make a decision for a large scale engineering project. A typical CBR system consists of four parts: case representation, case retriever, evaluation, and adaptation. A case library is a set of parameterized excellent and successful structures. For a structural choice, the key point is that the system must be able to detect the pattern classes hidden in the case library and classify the input parameters into classes properly. That is done by using the KDD Data Mining algorithm based on Self Organizing Feature Maps (SOFM), which makes the whole system more adaptive, self organizing, self learning and open.
文摘“Nothing can come of nothing”作为莎士比亚悲剧《李尔王》中的一句经典台词,深刻地绘就了早期李尔的精神底色。“无中不能生有”这个重要的哲学命题,自从被古希腊哲学家巴门尼德提出后,便为后世的西方哲学家所普遍讨论。在《李尔王》的英文原著中,“nothing”具有多元的内在含义。“有”与“没有”的讨论涉及了亲情、爱情多个方面,主人公观念中两者二元关系的转变也演绎着关于“真人”的成长故事。不论是对个体存在状态的呈现还是对人与自然动态关系的思考,《李尔王》都极具历史与现实两个维度的哲学价值。《李尔王》在双线索的交织中塑造出一众个性迥异而鲜明的人物形象,“有”与“没有”之间,暗含着“爱”的形式与本质之争,藏匿着“真人”成长蜕变的隐性轨迹。透过失势、战争、死亡、赎罪,我们思考生命存在的意义,审视社会关系的复杂,收获深沉的人性力量。
