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Iterative Signal Detection Based Soft Interference Cancellation for Satellite-Terrestrial Downlink NOMA Systems
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作者 Sun Meng Zhang Qi +5 位作者 Yao Haipeng Gao Ran Xin Xiangjun Tian Feng Feng Weiying Chen Dong 《China Communications》 SCIE CSCD 2024年第8期249-263,共15页
To improve the bit error rate(BER)performance of multi-user signal detection in satelliteterrestrial downlink non-orthogonal multiple access(NOMA)systems,an iterative signal detection algorithm based on soft interfere... To improve the bit error rate(BER)performance of multi-user signal detection in satelliteterrestrial downlink non-orthogonal multiple access(NOMA)systems,an iterative signal detection algorithm based on soft interference cancellation with optimal power allocation is proposed.Given that power allocation has a significant impact on BER performance,the optimal power allocation is obtained by minimizing the average BER of NOMA users.According to the allocated powers,successive interference cancellation(SIC)between NOMA users is performed in descending power order.For each user,an iterative soft interference cancellation is performed,and soft symbol probabilities are calculated for soft decision.To improve detection accuracy and without increasing the complexity,the aforementioned algorithm is optimized by adding minimum mean square error(MMSE)signal estimation before detection,and in each iteration soft symbol probabilities are utilized for soft-decision of the current user and also for the update of soft interference of the previous user.Simulation results illustrate that the optimized algorithm i.e.MMSE-IDBSIC significantly outperforms joint multi-user detection and SIC detection by 7.57dB and 8.03dB in terms of BER performance. 展开更多
关键词 non-orthogonal multiple access(NOMA) resource allocation satellite-terrestrial communication signal detection soft interference cancellation
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For LEO Satellite Networks: Intelligent Interference Sensing and Signal Reconstruction Based on Blind Separation Technology
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作者 Chengjie Li Lidong Zhu Zhen Zhang 《China Communications》 SCIE CSCD 2024年第2期85-95,共11页
In LEO satellite communication networks,the number of satellites has increased sharply, the relative velocity of satellites is very fast, then electronic signal aliasing occurs from time to time. Those aliasing signal... In LEO satellite communication networks,the number of satellites has increased sharply, the relative velocity of satellites is very fast, then electronic signal aliasing occurs from time to time. Those aliasing signals make the receiving ability of the signal receiver worse, the signal processing ability weaker,and the anti-interference ability of the communication system lower. Aiming at the above problems, to save communication resources and improve communication efficiency, and considering the irregularity of interference signals, the underdetermined blind separation technology can effectively deal with the problem of interference sensing and signal reconstruction in this scenario. In order to improve the stability of source signal separation and the security of information transmission, a greedy optimization algorithm can be executed. At the same time, to improve network information transmission efficiency and prevent algorithms from getting trapped in local optima, delete low-energy points during each iteration process. Ultimately, simulation experiments validate that the algorithm presented in this paper enhances both the transmission efficiency of the network transmission system and the security of the communication system, achieving the process of interference sensing and signal reconstruction in the LEO satellite communication system. 展开更多
关键词 blind source separation greedy optimization algorithm interference sensing LEO satellite communication networks signal reconstruction
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Contrastive Clustering for Unsupervised Recognition of Interference Signals
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作者 Xiangwei Chen Zhijin Zhao +3 位作者 Xueyi Ye Shilian Zheng Caiyi Lou Xiaoniu Yang 《Computer Systems Science & Engineering》 SCIE EI 2023年第8期1385-1400,共16页
Interference signals recognition plays an important role in anti-jamming communication.With the development of deep learning,many supervised interference signals recognition algorithms based on deep learning have emer... Interference signals recognition plays an important role in anti-jamming communication.With the development of deep learning,many supervised interference signals recognition algorithms based on deep learning have emerged recently and show better performance than traditional recognition algorithms.However,there is no unsupervised interference signals recognition algorithm at present.In this paper,an unsupervised interference signals recognition method called double phases and double dimensions contrastive clustering(DDCC)is proposed.Specifically,in the first phase,four data augmentation strategies for interference signals are used in data-augmentation-based(DA-based)contrastive learning.In the second phase,the original dataset’s k-nearest neighbor set(KNNset)is designed in double dimensions contrastive learning.In addition,a dynamic entropy parameter strategy is proposed.The simulation experiments of 9 types of interference signals show that random cropping is the best one of the four data augmentation strategies;the feature dimensional contrastive learning in the second phase can improve the clustering purity;the dynamic entropy parameter strategy can improve the stability of DDCC effectively.The unsupervised interference signals recognition results of DDCC and five other deep clustering algorithms show that the clustering performance of DDCC is superior to other algorithms.In particular,the clustering purity of our method is above 92%,SCAN’s is 81%,and the other three methods’are below 71%when jammingnoise-ratio(JNR)is−5 dB.In addition,our method is close to the supervised learning algorithm. 展开更多
关键词 interference signals recognition unsupervised clustering contrastive learning deep learning k-nearest neighbor
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Reflection on methodology of the correlation between electromagnetic interference and safety in high-speed railway
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作者 Chang Liu Shiwu Yang +2 位作者 Yixuan Yang Hefei Cao Shanghe Liu 《Railway Sciences》 2024年第1期84-96,共13页
Purpose – In the continuous development of high-speed railways, ensuring the safety of the operation controlsystem is crucial. Electromagnetic interference (EMI) faults in signaling equipment may cause transportation... Purpose – In the continuous development of high-speed railways, ensuring the safety of the operation controlsystem is crucial. Electromagnetic interference (EMI) faults in signaling equipment may cause transportationinterruptions, delays and even threaten the safety of train operations. Exploring the impact of disturbances onsignaling equipment and establishing evaluation methods for the correlation between EMI and safety isurgently needed.Design/methodology/approach – This paper elaborates on the necessity and significance of studying theimpact of EMI as an unavoidable and widespread risk factor in the external environment of high-speed railwayoperations and continuous development. The current status of research methods and achievements from theperspectives of standard systems, reliability analysis and safety assessment are examined layer by layer.Additionally, it provides prospects for innovative ideas for exploring the quantitative correlation between EMIand signaling safety.Findings – Despite certain innovative achievements in both domestic and international standard systems andrelated research for ensuring and evaluating railway signaling safety, there’s a lack of quantitative and strategic research on the degradation of safety performance in signaling equipment due to EMI. A quantitativecorrelation between EMI and safety has yet to be established. On this basis, this paper proposes considerationsfor research methods pertaining to the correlation between EMI and safety.Originality/value – This paper overviews a series of methods and outcomes derived from domestic andinternational studies regarding railway signaling safety, encompassing standard systems, reliability analysisand safety assessment. Recognizing the necessity for quantitatively describing and predicting the impact ofEMI on high-speed railway signaling safety, an innovative approach using risk assessment techniques as abridge to establish the correlation between EMI and signaling safety is proposed. 展开更多
关键词 Electromagnetic interference Reliability SAFETY Risk assessment signaling system High-speed railway
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Self-Mixing Interference Effects in LD Pumped Multi-Mode Solid-State Laser 被引量:2
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作者 张勇 姚建铨 +2 位作者 王鹏 禹延光 陈进 《Transactions of Tianjin University》 EI CAS 2003年第4期261-263,共3页
Based on the effective structure of the self-mixing interference effects,a general model for the self-mixing interference effects in the LD pumped solid-state laser has been established for the first time.The numerica... Based on the effective structure of the self-mixing interference effects,a general model for the self-mixing interference effects in the LD pumped solid-state laser has been established for the first time.The numerical simulation of the self-mixing interference signal has been done,the results show that when the external cavity length is integral times of 1/2,1/3,2/3,1/4,3/4 of the effective cavity length,the intensity of the self-mixing interference signals reach maximum in value.While that of single mode laser is integral times of half of the effective cavity length,the measuring precision of displacement of single mode laser is λ/2.A conclusion can be drawn from the above results that the measuring precision of displacement of multi-mode laser is higher than that of single mode laser. 展开更多
关键词 general model self-mixing interference effects LD pumped multi-mode solid-state laser numerical simulations
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Sub-external cavity effect and elimination method in laser self-mixing interference wave plate measurement system 被引量:1
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作者 牛海莎 牛燕雄 宋建军 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第2期349-354,共6页
Laser self-mixing interference(SMI) wave plate measurement method is a burgeoning technique for its simplicity and efficiency. But for the non-coated sample, the reflected light from the surface can seriously affect... Laser self-mixing interference(SMI) wave plate measurement method is a burgeoning technique for its simplicity and efficiency. But for the non-coated sample, the reflected light from the surface can seriously affect the measurement results.To analyze the reason theoretically, a self-consistent model for laser operation with a sub-external and an external cavity is established, and the sub-external cavity formed by the sample and a cavity mirror is proved to be the main error source.A synchronous tuning method is proposed to eliminate the sub-external cavity effect. Experiments are carried out on the synchronously tuning double external cavities self-mixing interference system, and the error of the system is in the range of -0.435°~0.387° compared with the ellipsometer. The research plays an important role in improving the performance and enlarging the application range of the laser self-mixing interference system. 展开更多
关键词 self-mixing interference non-coated wave plate measurement self-consistent model
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Laser self-mixing interference fibre sensor
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作者 朱钧 赵燕 金国藩 《Chinese Physics B》 SCIE EI CAS CSCD 2008年第8期2979-2983,共5页
Fibre sensors exhibit a number of advantages over other sensors such as high sensitivity, electric insulation, corrosion resistance, interference rejection and so on. And laser self-mixing interference can accurately ... Fibre sensors exhibit a number of advantages over other sensors such as high sensitivity, electric insulation, corrosion resistance, interference rejection and so on. And laser self-mixing interference can accurately detect the phase difference of feedback light. In this paper, a novel laser self-mixing interference fibre sensor that combines the advantages of fibre sensors with those of laser self-mixing interference is presented. Experimental configurations are set up to study the relationship between laser power output and phase of laser feedback light when the fibre trembles or when the fibre is stretched or pressed. The theoretical analysis of pressure sensors based on laser self-mixing interference is indicated to accord with the experimental results. 展开更多
关键词 laser self-mixing interference fibre sensor
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An Optical Path Length Modulator for Laser Diode Self-Mixing Interference
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作者 Xianfeng Hu 《Optics and Photonics Journal》 2017年第1期1-5,共5页
Transparent liquid flattening or stretching realizes optical path length modulation. A flat thin seal transparent cavity, one flank is an electromagnetic driving membrane and is filled over with transparent liquid. Vi... Transparent liquid flattening or stretching realizes optical path length modulation. A flat thin seal transparent cavity, one flank is an electromagnetic driving membrane and is filled over with transparent liquid. Vibration of the membrane makes the liquid compressing or stretching, changes the liquid layer thickness, i.e. the optical path length of light through the liquid layer. The liquid layer compressed is equivalent to increase membrane tension. The membrane has higher resonant frequency. The cavity diameter 10 mm modulation frequency is about 18 kHz. 展开更多
关键词 self-mixing interference OPTICAL PATH Length Phase MODULATOR Vibration
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Weak harmonic signal detection method in chaotic interference based on extended Kalman filter 被引量:9
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作者 Chengye Lu Sheng Wu +1 位作者 Chunxiao Jiang Jinfeng Hu 《Digital Communications and Networks》 SCIE 2019年第1期51-55,共5页
The traditional methods of weak harmonic signal detection under strong chaotic interference often suffer from high computational complexity and poor performance. In this paper, an Extended Kalman Filter (EKF) based de... The traditional methods of weak harmonic signal detection under strong chaotic interference often suffer from high computational complexity and poor performance. In this paper, an Extended Kalman Filter (EKF) based detection method is proposed for the detection of weak harmonic signal. The EKF method avoids matrix inversion by iterating measurement equation and state equation, which simultaneously improves the robustness and reduces the complexity. Compared with the existing detection methods, the proposed method has the following advantages: 1) it has better performance than the neural network method;2) it has similar performance with the optimal filtering method, but with lower computational complexity;3) it is more robust compared with the optimal filtering method. 展开更多
关键词 Extended KALMAN filter STRONG CHAOTIC interference WEAK HARMONIC signal
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Silencing of signal transducer and activator of transcription 3 expression by RNA interference suppresses growth of human hepatocellular carcinoma in tumor-bearing nude mice 被引量:13
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作者 Jing Li Yun-Feng Piao +2 位作者 Zheng Jiang Li Chen Hai-Bo Sun 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第21期2602-2608,共7页
AIM: To explore the effect of silencing of signal transducer and activator of transcription 3 (STAT3) expression by RNA interference (RNAi) on growth of human hepatocellular carcinoma (HCC) in tumorbearing nude... AIM: To explore the effect of silencing of signal transducer and activator of transcription 3 (STAT3) expression by RNA interference (RNAi) on growth of human hepatocellular carcinoma (HCC) in tumorbearing nude mice in vivo.METHODS: To construct the recombinant plasmid of pSilencer 3.0-H1-STAT3-siRNA-GFP (pSHI-siRNA- STAT3) and establish the tumor-bearing nude mouse model of the HCC cell line SMMC7721, we used intratumoral injection together with electroblotting to transfect the recombinant plasmid pSHI-siRNA- STAT3 into the transplanted tumor. The weight of the nude mice and tumor volumes were recorded. STAT3 gene transcription was detected by semi-quantitative reverse transcription polymerase chain reaction (RT- PCR). Level of protein expression and location of STAT3 were determined by Western blotting and immunohistochemical staining. STAT3-related genes such as survivin, c-myc, VEGF, p53 and caspase3 mRNA and protein expression were detected in tumor tissues at the same time. The terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay was used to detect apoptosis of tumor cells.RESULTS: The weight of the treated nude mice increased, and the tumor volume decreased markedly compared with those of the mock-treated and negative control groups (P 〈 0.01). The results of RT-PCR and Western blotting showed that mRNA and protein levels of STAT3 declined markedly in the treated group. The change in STAT3-related gene expression in tumor tissues at the mRNA and protein level also varied, the expression of survivin, VEGF and c-myc were obviously reduced, and expression of p53 and caspase3 increased (P 〈 0.01). Most of the tumor tissue ceils in the treated group developed apoptosis that was detected by TUNEL assay.CONCLUSION: Silencing of STAT3 expression by RNAi significantly inhibits expression of STAT3 mRNA and protein, and suppresses growth of human HCC in tumor-bearing nude mice. The mechanism may be related to down-regulation of survivin, VEGF and c-myc and up-regulation of p53 and caspase3 expression. Accordingly, the STAT3 gene may act as an important and effective target in gene therapy of HCC. 展开更多
关键词 RNA interference signal transducerand activator of transcription 3 transcription factor Hepatocellular carcinoma Xenograft model antitumorassays Nude mouse
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Analysis of the Interference Signal of the Distributed Optical Fiber Sensing Based on DSP 被引量:3
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作者 Tingting Du Xiong Wan +2 位作者 Zhimin Zhang Huming Zhang Qing Zhang 《Optics and Photonics Journal》 2013年第2期122-125,共4页
In this paper, the author analyzes characteristics and extracting method of interference signal of the distributed optical fiber sensing. In the distributed optical fiber sensing, realizing alarm and positioning funct... In this paper, the author analyzes characteristics and extracting method of interference signal of the distributed optical fiber sensing. In the distributed optical fiber sensing, realizing alarm and positioning function only through the cross-correlation operation will increase the load of the system, can make misinformation rate of the system be improved greatly. Therefore, before the localization algorithm, adding a interference signal feature recognition is very necessary, can reduce unnecessary operation loss and reduce the load of the system, also reducing the number of the false positives. 展开更多
关键词 The Optical Fiber SENSING MACH-ZEHNDER interferOMETER Energy interference signal signal RECOGNITION
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NEW SELF-MIXING MICRO-INTERFEROMETER BASED ON EXTERNAL PHASE MODULATION 被引量:1
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作者 GUO Dongmei WANG Ming 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2007年第3期83-85,共3页
ASeblsf-tmraicxti:n gA innteewrf esreelnf-cme ioxcincgu rms iicnr oa -liansteerrf derioodmee t(eLrD b)a sbeyd r eofnl eecxtitnergn tahl ep lhiagshet fmroomdu ala tmioinrr oisr-plirkees etanrtgedet. in front of the ... ASeblsf-tmraicxti:n gA innteewrf esreelnf-cme ioxcincgu rms iicnr oa -liansteerrf derioodmee t(eLrD b)a sbeyd r eofnl eecxtitnergn tahl ep lhiagshet fmroomdu ala tmioinrr oisr-plirkees etanrtgedet. in front of the laser. Sinusoidal phase modulation of the beam is obtained by an electro-optic crystal (EOC) in the external cavity. The phase of the interference signal is demodulated by Fourier analysis method. The combination of the modulation and demodulation decreases the sensitivity of the instru-ment to fluctuations of the laser power and the noise induced by environment. Experimentally, the new micro-interferometer is applied to measure the micro-displacement of a high precision commer-cial PZT with an accuracy of 〈10 nm. 展开更多
关键词 Micro-interferometer self-mixing interference Displacement measurement
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Leak Detection of Gas Pipelines Based on Characteristics of Acoustic Leakage and Interfering Signals 被引量:2
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作者 Lingya Meng Cuiwei Liu +2 位作者 Liping Fang Yuxing Li Juntao Fu 《Sound & Vibration》 2019年第4期111-128,共18页
When acoustic method is used in leak detection for natural gas pipelines,the external interferences including operation of compressor and valve,pipeline knocking,etc.,should be distinguished with acoustic leakage sign... When acoustic method is used in leak detection for natural gas pipelines,the external interferences including operation of compressor and valve,pipeline knocking,etc.,should be distinguished with acoustic leakage signals to improve the accuracy and reduce false alarms.In this paper,the technologies of extracting characteristics of acoustic signals were summarized.The acoustic leakage signals and interfering signals were measured by experiments and the characteristics of time-domain,frequency-domain and time-frequency domain were extracted.The main characteristics of time-domain are mean value,root mean square value,kurtosis,skewness and correlation function,etc.The features in frequency domain were obtained by frequency spectrum analysis and power spectrum density,while time-frequency analysis was accomplished by short time Fourier transform.The results show that the external interferences can be removed effectively by the characteristics of time domain,frequency domain and time-frequency domain.It can be drawn that the acoustic leak detection method can be applied to natural gas pipelines and the characteristics can help reduce false alarms and missing alarms. 展开更多
关键词 Leak detection acoustic method signal processing external interference characteristic extraction
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PIM Interference Analysis under Multi-band Multi-signal Input in Duplex Indoor Distribution System 被引量:2
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作者 Pauling Huang 《China Communications》 SCIE CSCD 2007年第3期79-87,共9页
This analysis focuses on PIM interference under multi-band multi-signal input in mobile communication system.Unlike single band system that only odd order PIM(especially 3rd order) should be concerned,in multi-band mu... This analysis focuses on PIM interference under multi-band multi-signal input in mobile communication system.Unlike single band system that only odd order PIM(especially 3rd order) should be concerned,in multi-band multi-signal case,both odd and even order PIM could be interference source because of more complicated intermodulation,more IMPs generated and more receive bands.Especially,the 2nd order PIM may interfere more serious to receiving channel for its strong magnitude.In duplex indoor distribute system,the PIM interference is a potential problem to GSM900,DCS1800,CDMA,and even 3G system wireless services,because the PIM frequencies may fall in receive bands and interfere to the receiving channels.In radio system design and wireless channel assignment,precautions must be taken to minimize the PIM level and to avoid interfere to receiving channels.For practical use,the lower order possible PIM interference to 2G and 3G systems is calculated. 展开更多
关键词 PIM IMP interference MULTI-BAND multi-signal 2G and 3G systems
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Signal-to-noise ratio of lensless ghost interference with thermal incoherent light 被引量:1
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作者 张二峰 戴宏毅 陈平形 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第2期229-234,共6页
Factors influencing the signal-to-noise ratio (SNR) of lensless ghost interference with thermal incoherent light are investigated. Our result shows that the SNR of lensless ghost interference is related to the trans... Factors influencing the signal-to-noise ratio (SNR) of lensless ghost interference with thermal incoherent light are investigated. Our result shows that the SNR of lensless ghost interference is related to the transverse length of the object, the position of the object in the imaging system and the transverse size of the light source. Furthermore, the effects of these factors on the SNR are discussed in detail by numerical simulations. 展开更多
关键词 ghost interference ghost imaging signal-to-noise ratio
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5G Oriented Exponential Effective Signal to Interference plus Noise Ratio Mapping Algorithm Based on Channel Classification
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作者 WU Haoran YE Jianfang 《Journal of Donghua University(English Edition)》 EI CAS 2018年第2期160-162,共3页
In the future the fifth generation( 5 G) communication systems,channel models may be very complicated and it is difficult to calculate equivalent signal to interference plus noise ratio( SINR)of a random fading channe... In the future the fifth generation( 5 G) communication systems,channel models may be very complicated and it is difficult to calculate equivalent signal to interference plus noise ratio( SINR)of a random fading channel. Therefore,methods for the calculation of equivalent SINR of a random fading channel are very necessary.In this paper,an enhanced algorithm on the exponential effective SINR mapping( EESM) model for random fading channels was proposed. First, the optimal adjustment parameters of typical channel fading models including extended pedestrian A( EPA)model,extended vehicular A( EVA) model and extended typical urban( ETU) model were obtained by simulation. Then the proposed solution was used to actualize channel classification according to the maximum multipath delay and the average power of the random channel. The solution can determine the typical channel closest to random channel for obtaining the optimal adjustment value of EESM. The evaluation results indicate that the proposed one can improve the whole system throughput significantly and meanwhile the accuracy of the link prediction algorithm is also guaranteed. 展开更多
关键词 the fifth generation (5G) signal to interference PLUS noiseratio (SINR) EXPONENTIAL EFFECTIVE SINR mapping (EESM) channel classification
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Rejection of Direct Blast Interference Based on Signal Phase-Matching Array Processing
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作者 Yun-Fei Chen Zhen-Shan Wang +1 位作者 Bing Jia Gui-Juan Li 《Journal of Electronic Science and Technology》 CAS 2013年第1期106-109,共4页
In bistaic acoustic testing, there will be strong direct blast interference. An algorithm based on signal phase-matching array processing that rejects direct blast interference in bistatic acoustic testing has been st... In bistaic acoustic testing, there will be strong direct blast interference. An algorithm based on signal phase-matching array processing that rejects direct blast interference in bistatic acoustic testing has been studied, through which the object scattering signal is accurately extracted. Characteristics of bistatic acoustic testing and signal phase matching processing principle are fully integrated in this algorithm. Firstly, the direct blast interference is calculated from the receiving signal based on three subarrays signal phase matching processing. Secondly, the direct blast is rejected by subtraction from the receiving signal. In this way the limitations of the high signal to noise ratio that signal phase matching processing required for direct calculating the object scattering signal can be avoided. Simulation and sea trial results show that, when the ratio of signal to interference is greater than -20 dB, this algorithm of direct blast interference rejection based phase matching signal processing can accurately extract the object scattering signal. 展开更多
关键词 Bistatic acoustic testing direct blast interference rejection signal phase matching processing.
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Monitoring and Recognition of Debris Flow Infrasonic Signals 被引量:12
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作者 LIU Dun-long LENG Xiao-peng +2 位作者 WEI Fang-qiang ZHANG Shao-jie HONG Yong 《Journal of Mountain Science》 SCIE CSCD 2015年第4期797-815,共19页
Low frequency infrasonic waves are emitted during the formation and movement of debris flows, which are detectable in a radius of several kilometers, thereby to serve as the precondition for their remote monitoring.Ho... Low frequency infrasonic waves are emitted during the formation and movement of debris flows, which are detectable in a radius of several kilometers, thereby to serve as the precondition for their remote monitoring.However, false message often arises from the simple mechanics of alarms under the ambient noise interference.To improve the accuracy of infrasound monitoring for early-warning against debris flows, it is necessary to analyze the monitor information to identify in them the infrasonic signals characteristic of debris flows.Therefore, a large amount of debris flow infrasound and ambient noises have been collected from different sources for analysis to sum up their frequency spectra, sound pressures, waveforms, time duration and other correlated characteristics so as to specify the key characteristic parameters for different sound sources in completing the development of the recognition system of debris flow infrasonic signals for identifying their possible existence in the monitor signals.The recognition performance of the system has been verified by simulating tests and long-term in-situ monitoring of debris flows in Jiangjia Gully,Dongchuan, China to be of high accuracy and applicability.The recognition system can provide the local government and residents with accurate precautionary information about debris flows in preparation for disaster mitigation and minimizing the loss of life and property. 展开更多
关键词 Debris flow INFRASOUND interference noise MONITORING signal recognition
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Lentivirus-mediated shRNA interference targeting STAT3 inhibits human pancreatic cancer cell invasion 被引量:19
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作者 Guang Yan Chen Huang Jun Cao Ke-Jian Huang Tao Jiang Zheng-Jun Qiu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第30期3757-3766,共10页
AIM: To investigate RNA interference targeting signal transducer and activator of transcription-3 (STAT3) on invasion of human pancreatic cancer cells.METHODS: We constructed three plasmids of RNA interference tar... AIM: To investigate RNA interference targeting signal transducer and activator of transcription-3 (STAT3) on invasion of human pancreatic cancer cells.METHODS: We constructed three plasmids of RNA interference targeting the STAT3 gene. After LV (lentivirus)-STAT3siRNA (STAT3 small interfering RNA) the vector was transfected into the human pancreatic cell line, SW1990 and cell proliferation was measured by the MTT assay. Flow cytometry was used to assess cell cycle. Vascular endothelial growth favor (VEGF) and matrix metalloproteinase-2 (MMP-2) mRNA and protein expression were examined by quantitative PCR and western blotting, respectively. The invasion ability of SW1990 cells was determined by cell invasion assay.RESULTS: We successfully constructed the LVSTAT3siRNA lentivirus vector and proved that it can suppress expression of STAT3 gene in SW1990 cells. RNA interference of STAT3 by the LV-STAT3siRNA construct significantly inhibited the growth of SW1990 cells, in addition to significantly decreasing both VEGF and MMP-2 mRNA and protein expression. Moreover, suppression of STAT3 by LV-STAT3siRNA decreased the invasion ability of SW1990 cells.CONCLUSION: The STAT3 signaling pathway may provide a novel therapeutic target for the treatment of pancreatic cancer since it inhibits the invasion ability of pancreatic cancer cells. 展开更多
关键词 signal transducer and activator of transcription3 RNA interference Lentivirus vector Pancreatic cancercells INVASION
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Narrow-band interference excision in spread-spectrum systems using new N-sigma algorithm based on fuzzy threshold 被引量:4
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作者 Feng Jining Wu Siliang Wang Ju 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2009年第1期20-26,共7页
The key to narrow-band interference excision in frequency domain is to determine the excision thresh- old in direct-sequence spread-spectrum (DS-SS) systems. The excision threshold is a non-linear function related t... The key to narrow-band interference excision in frequency domain is to determine the excision thresh- old in direct-sequence spread-spectrum (DS-SS) systems. The excision threshold is a non-linear function related to the number and the power of interference, and attempting to get the exact relation of threshold related to the number and the power of interference is almost impossible. The N-sigma algorithm determines the excision threshold using subsection function; however, the excision threshold determined by this method is not exact. A new method to determine the threshold of N-sigma algorithm is proposed. The new method modifies the scale factor N by use of the membership function. The threshold determined by this method is consecutive and smooth, and it is closer to the fact than that of the initial N-sigma algorithm. The GPS signal and single-tone (CW) interference (that is, typical narrow-band interference) are implemented in the simulation, and the results are presented to demonstrate the validity of the new algorithm. 展开更多
关键词 direct-sequence spread-spectrum systems adaptive frequency domain interference suppression fuzzyfunction GPS signal.
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