Dominant phase-advanced driving analysis of self-sustained oscillations in biological networks

Oscillatory behaviors can be ubiquitously observed in various systems. Biological rhythms are significant in governing living activities of all units. The emergence of biological rhythms is the consequence of large numbers of units. In this paper we discuss several important examples of sustained oscillations in biological media, where the unit composed in the system does not possess the oscillation behavior. The dominant phase-advanced driving method is applied to study the skeletons and oscillatory organizing motifs in excitable networks and gene regulatory networks.

Numerical Simulation of Flow over an Open Cavity with Self-Sustained Oscillation Mode Switching

Numerical simulations are used to investigate the self-sustained oscillating flows past an open cavity. The two-dimensional incompressible Navier-Stokes equations are solved directly by using the finite difference method for cavities with an upstream laminar boundary layer. A series of simulations are performed for a variety of cavity length-to-depth ratio. The results show the switching among some flow modes including non-oscillation mode, shear layer mode and wake mode. The variation of the Strouhal number is in favorable agreement with available experimental data. The results of flow fields in the cavity reveal the relationship between the cavity shear layer oscillation modes and recirculating vortices in the cavity.

Self-sustained Oscillation Pulsed Air Blowing System for Energy Saving

Currently, many studies have been made for years on dimensions of pneumatic nozzle, which influence the flow characteristic of blowing system. For the purpose of outputting the same blowing force, the supply pressure could be reduced by decreasing the ratio of length to diameter of nozzle. The friction between high speed air and pipe wall would be reduced if the nozzle is designed to be converging shape comparing with straight shape. But the volume flow and pressure, discussed in these studies, do not describe energy loss of the blowing system directly. Pneumatic power is an innovative principle to estimate pneumatic system’s energy consumption directly. Based on the above principle, a pulse blowing method is put forward for saving energy. A flow experiment is carried out, in which the high speed air flows from the pulse blowing system and continuous blowing system respectively to a plate with grease on top. Supply pressure and the volume of air used for removing the grease are measured to calculate energy consumption. From the experiment result, the pulse blowing system performs to conserve energy comparing with the continuous blowing system. The frequency and duty ratio of pulse flow influence the blowing characteristic. The pulse blowing system performs to be the most efficient at the specified frequency and duty ratio. Then a pneumatic self-oscillated method based on air operated valve is put forward to generate pulse flow. A simulation is made about dynamic modeling the air operated valve and calculating the motion of the valve core and output pressure. The simulation result verifies the system to be able to generate pulse flow, and predicts the key parameters of the frequency and duty ratio measured by experiment well. Finally, on the basis of simplifying and solution of the pulse blowing system’s mathematic model, the relationship between system’s frequency duty ratio and the dimensions of components is simply described with four algebraic equations. The system could be designed with specified frequency and duty ratio according to the four equations. This study provides theoretical basis for designing energy-saving air blowing system.

Numerical simulation of flow field characteristics and the improvement of pressure oscillation of rotating detonation engine

Due to the inherent working mode of rotating detonation engine(RDE),the detonation flow field has the characteristics of pressure oscillation and axial kinetic energy loss,which makes it difficult to design nozzle and improve propulsion performance.Therefore,in order to improve the characteristics of detonation flow field,the three-dimensional numerical simulation of annular chamber and hollow chamber is carried out with premixed hydrogen/air as fuel in this paper,and then tries to combine the two chambers to weaken the oscillation characteristics of detonation flow field through the interaction of detonation flow field,which is a new method to regulate the detonation flow field.The results show that there are four states of velocity vectors at the outlet of annular chamber and hollow chamber,which makes RDE be affected by rolling moment and results in the loss of axial kinetic energy.In the external flow field of combined chamber,the phenomenon of cyclic reflection of expansion wave and compression wave on the free boundary is observed,which results in Mach disk structure.Moreover,the pressure monitoring points are set at the external flow field.The pressure signal shows that the high-frequency pressure oscillation at the external flow field of the combined chamber has been greatly weakened.Compared to the annular chamber,the relative standard deviation(RSD) has been reduced from 14.6% to5.6%.The results thus demonstrate that this method is feasible to adjust the pressure oscillation characteristics of the detonation flow field,and is of great significance to promote the potential of RDE and nozzle design.

A Possible Minimum Toy Model with Negative Differential Capacitance for Self-sustained Current Oscillation

We generalize a simple model for superlattices to include the effect of differential capacitance. It is shown that the model always has a stable steady-state solution （SSS） if all differential capacitances are positive. On the other hand, when negative differential capacitance is included, the model can have no stable SSS and be in a self-sustained current oscillation behavior. Therefore, we find a possible minimum toy model with both negative differential resistance and negative differential capacitance which can include the phenomena of both self-sustained current oscillation and I-V oscillation of stable SSSs.

Averaged Dynamics of Fluids near the Oscillating Interface in a Hele-Shaw Cell

The steady flow in a Hele-Shaw cell filled with fluids with a high viscosity contrast in the presence of fluid oscillations is experimentally studied.The control of oscillatory dynamics of multiphase systems with interfaces is a challenging technological problem.We consider miscible(water and glycerol)and immiscible(water and high-viscosity silicone oil PMS-1000)fluids under subsonic oscillations perpendicular to the interface.Observations show that the interface shape depends on the amplitude and frequency of oscillations.The interface is undisturbed only in the absence of oscillations.Under small amplitudes,the interface between water and glycerol widens due to mixing.When the critical amplitude is reached,the interface becomes unstable to the fingering instability:Aqueous fingers penetrate the high-viscosity glycerol and induce intensive mixing of miscible fluids and associated decay of the instability.After the disappearance of the fingers,the interface takes a U-shape in the central part of the cell.A similar effect is observed for immiscible fluids:The oscillating interface tends to bend to the side of a high-viscosity fluid.Again,when the critical amplitude is reached,the fingering instability arises at the convex interface.This paper focuses on the causes of bending of the initially undisturbed interface between miscible or immiscible fluids.For this purpose,we measure the steady flow velocity near the interface and in the bulk of a high-viscosity fluid using Particle Image Velocimetry(PIV).

Shear flow induced vibrations of long slender cylinders with a wake oscillator model

A time domain model is presented to study the vibrations of long slender cylinders placed in shear flow. Long slender cylinders such as risers and tension legs are widely used in the field of ocean engineering. They are subjected to vortex-induced vibrations（VIV） when placed within a transverse incident flow. A three dimensional model coupled with wake oscillators is formulated to describe the response of the slender cylinder in cross-flow and in-line directions. The wake oscillators are distributed along the cylinder and the vortex-shedding frequency is derived from the local current velocity. A non-linear fiuid force model is accounted for the coupled effect between cross-flow and in-line vibrations. The comparisons with the published experimental data show that the dynamic features of VIV of long slender cylinder placed in shear flow can be obtained by the proposed model,such as the spanwise average displacement,vibration frequency,dominant mode and the combination of standing and traveling waves. The simulation in a uniform flow is also conducted and the result is compared with the case of nonuniform flow. It is concluded that the flow shear characteristic has significantly changed the cylinder vibration behavior.

Scour of the Seabed Under A Pipeline in Oscillating Flow

The scour of the seabed under a pipeline is studied experimentally in this paper. Tests are carried out in a U-shaped oscillatory water tunnel with a box imbedded in the bottom of the test section. By use of the standard sand, clay and plastic grain as the seabed material, the influence of the bed material on the scour is studied. The relationship between the critical initial gap-to-diameter ratio above which no scour occurs and the parameters of the oscillating flow is obtained. The self-burial phenomenon. which occurs for the pipeline not fixed to two sidewalls of the test section, is not observed for the Bred pipeline. The effect of the pipe on sand wave formation is discussed. The maximum equilibrium scour depths For different initial gap-to-diameter ratios, different Kc numbers and different bed sands are also given in this paper.

Combined Action of Uniform Flow and Oscillating Flow Around Marine Riser at Low Keulegan-Carpenter Number

With the increase of petroleum and gas production in deep ocean, marine risers of circular cylinder shape are widely used in the offshore oil and gas platform. In order to research the hydrodynamic performance of marine risers, the dynamic mesh technique and User-Defined Function(UDF) are used to simulate the circular cylinder motion. The motion of a transversely oscillating circular cylinder in combination of uniform flow and oscillating flow is simulated. The uniform flow and oscillating flow both are in x direction. SIMPLE algorithm is used to solve the Navier-Stokes equations. The User-Defined Function is used to control the cylinder transverse vibration and the inlet flow. The lift and drag coefficient changing with time and the map of vorticity isolines at different phase angle are obtained. Force time histories are shown for uniform flow at Reynolds number(Re) of 200 and for the combination of uniform and oscillating flows. With the increase of amplitude of oscillating flow in combined flow, the change of lift amplitude is not sensitive to the the change of cylinder oscillating frequency. Lift amplitude increases with the increase of oscillating flow amplitude in the combined flow, but there is no definite periodicity of the lift coefficient. The drag and inertia force coefficients change when the maximum velocity of the oscillating flow increases in the combined flow. The vortex shedding near the circular cylinder shows different characteristics.

Numerical Simulation and Experimental Investigation on Performance of the Wells Turbine in Irregular Oscillating Flow

The Wells turbine is an axial-flow air-turbine designed to extract energy from ocean waves. An important consideration is the self-starting capability of the Wells turbine, a phenomenon encountered where the turbine accelerate by itself up to a certain speed for the best turbine performance. In order to clarify the self-starting characteristic and running performance of the Wells turbine in an irregular oscillating flow, a numerical simulation process is established in this paper on the rational assumption of quasi-steady flow conditions, Both self-starting characteristics and running performance are obtained through the numerical simulation and subsequently compared with the experimental data achieved on a computer-controlled oscillating flow test rig which could realize some irregular oscillating flow according to the specified spectrum. Results show that the self-starting time decreases with the increase of the significant wave height and the mean frequency of the irregular oscillating flow, Therefore, it is possible to predict accurately the performance of the Wells turbine by computer simulation.

Mode transition and oscillation suppression in supersonic cavity flow

Supersonic flows past two-dimensional cavities with/without control are investigated by the direct numerical simulation （DNS）. For an uncontrolled cavity, as the thickness of the boundary layer declines, transition of the dominant mode from the steady mode to the Rossiter Ⅱ mode and then to the Rossiter III mode is observed due to the change of vortex-corner interactions. Meanwhile, a low frequency mode appears. However, the wake mode observed in a subsonic cavity flow is absent in the current simulation. The oscillation frequencies obtained from a global dynamic mode decomposition （DMD） approach are consistent with the local power spectral density （PSD） analysis. The dominant mode transition is clearly shown by the dynamic modes obtained from the DMD. A passive control technique of substituting the cavity trailing edge with a quarter-circle is studied. As the effective cavity length increases, the dominant mode transition from the Rossiter Ⅱ mode to the Rossiter Ⅲ mode occurs. With the control, the pressure oscillations are reduced significantly. The interaction of the shear layer and the recirculation zone is greatly weakened, combined with weaker shear layer instability, responsible for the suppression of pressure oscillations. Moreover, active control using steady subsonic mass injection upstream of a cavity leading edge can stabilize the flow.

Application of time–frequency entropy from wake oscillation to gas–liquid flow pattern identification

Gas–liquid two-phase flow abounds in industrial processes and facilities. Identification of its flow pattern plays an essential role in the field of multiphase flow measurement. A bluff body was introduced in this study to recognize gas–liquid flow patterns by inducing fluid oscillation that enlarged differences between each flow pattern. Experiments with air–water mixtures were carried out in horizontal pipelines at ambient temperature and atmospheric pressure. Differential pressure signals from the bluff-body wake were obtained in bubble, bubble/plug transitional, plug, slug, and annular flows. Utilizing the adaptive ensemble empirical mode decomposition method and the Hilbert transform, the time–frequency entropy S of the differential pressure signals was obtained. By combining S and other flow parameters, such as the volumetric void fraction β, the dryness x, the ratio of density φ and the modified fluid coefficient ψ, a new flow pattern map was constructed which adopted S（1–x）φ and （1–β）ψ as the vertical and horizontal coordinates, respectively. The overall rate of classification of the map was verified to be 92.9% by the experimental data. It provides an effective and simple solution to the gas–liquid flow pattern identification problems.

Transport of dissolved oxygen at the sediment-water interface in the spanwise oscillating flow

The distribution and concentration of dissolved oxygen(DO)play important roles in aerobic heterotroph activities and some slow chemical reactions,and can affect the water quality,biological communities,and ecosystem functions of rivers and lakes.In this work,the transport of high Schmidt number DO at the sediment-water interface of spanwise oscillating flow is investigated.The volume-averaged Navier-Stokes(VANS)equations and Monod equation are used to describe the flow in the sediment layer and the sediment oxygen demand of microorganisms.The phase-averaged velocities and concentrations of different amplitudes and periods are studied.The dependence of DO transfer on the amplitude and period is analyzed by means of phase-average statistical quantities.It is shown that the concentration in the sediment layer is positively correlated with the turbulence intensity,and the DO concentration and penetration depth in the sediment layer increases when the period and amplitude of the oscillating flow increase.Moreover,in the presence of oscillating flow,a specific scaling relationship exists between the Sherwood number/oxygen consumption of aerobic heterotrophs and the Reynolds number.

Experimental and numerical study of the effect of pulsatile flow on wall displacement oscillation in a flexible lateral aneurysm model

This study experimentally and numerically investigated the effect of pulsatile flow of different frequencies and outflow resistance on wall deformation in a lateral aneurysm.A method for constructing a flexible aneurysm model was developed,and a self-designed piston pump was used to provide the pulsatile flow conditions.A fluid-structure interaction simulation was applied for comparison with and analysis of experimental findings.The maximum wall displacement oscillation increased as the pulsation frequency and outflow resistance increased,especially at the aneurysm dome.There is an obvious circular motion of the vortex center accompanying the periodic inflow fluctuation,and the pressure at the aneurysm dome at peak flow increased as the pulsatile flow frequency and terminal flow resistance increased.These results could explain why abnormal blood flow with high frequency and high outflow resistance is one of the risk factors for aneurysm rupture.

EXPERIMENTAL AND NUMERICAL INVESTIGATIONS OF BOTH FLOW INDUCED CAVITY OSCILLATION AND ITS SUPPRESSION BY ACOUSTIC EXCITATION

Flow induced oscillation in a cavity and its suppression by means of acoustic excitation were studied both experimentally and numerically. In the experiment it was found that with the leading edge pure tone excitation at some frequencies and intensities. the flow-induced oscillation in the cavity could be greatly suppressed. Cavity flows both with and without acoustic excitation were studied by solving the 2-D time-dependent Reynolds averaged Navier Stokes equations using explicit predictor-corrector difference algorithm of MacCormack. Effects of turbulence were simulated via Cebeci-Smith turbulence mode with relaxation modification. The computational and experimental results are compared. and good agreement is obtained.

A NUMERICAL STUDY OF THE VORTEX MOTION IN OSCILLATING FLOW AROUND A CIRCULAR CYLINDER AT LOW AND MIDDLE Kc NUMBERS

A new hybrid model, which is based on domain decomposition and proposed by the authors is used for calculating the flow around a circular cylinder at low and middle Keulegan-Carpenter numbers (Kc=2～18)respectively.The vortex motion patterns in asymmetric regime,single pair(or transverse)regime and double pair(or diagonal)regime are successfully simulated.The calculated drag and inertial force coefficients are in better agreement with experimental data than other recent computational results.

Solution of MHD Flow past a Vertical Porous Plate through a Porous Medium under Oscillatory Suction

The model of mass transfer on free convective flow of a viscous incompressible electrically conducting fluid past vertically porous plate through a porous medium with time dependant permeability and oscillatory suction in presence of a transverse magnetic field is considered. Perturbation technique is obtained the solution for velocity field and concentration distribution analytically. The effects of the flow parameters on the velocity field and concentration distribution are presented with the aid of figures. Also, the skin friction and the rate of mass transfer are calculated with the aid of tables.

Effect of Oscillation Parameters to Flow Field in the Pool during the Oscillating Twin-Roll Strip Casting Process

During the oscillating twin?roll strip casting process, the quality of final products is directly influenced by the flow field distribution of molten metal in the pool. The variation in the flow field is caused by oscillating roller benefits, for homogeneous distribution of strip impurity, and decreasing the grain size. Thus, the quality of the strip could be improved. A numerical model was developed using the multiphase flow technology, coupled with heat transfer, fluid flow, solidification, and oscillation. Furthermore, a transient algorithm was adopted for simulating the oscillating twin?roll strip casting process of AlSi9Cu3 and 3104 aluminum alloy. This paper focuses on the flow distribution in the pool, in comparison with the traditional vertical twin?roll strip casting process, while the amplitude or frequency is chang?ing with the definite value of casting velocity, roller diameter, nozzle angle, and the strip thickness. Consequently, the conclusions were experimentally validated by oscillating twin?roll 3104 aluminum alloy strip casting. Vibrating casting technology can change the flow field in the pool by vibration, which can improve the quality of the strip core.

Experimental Study on Flow past A Rotationally Oscillating Cylinder

A series of experiments was carried out to study the flow behaviour behind a rotationally oscillating cylinder at a low Reynolds number （Re=300） placed in a recirculation water channel. A stepper motor was used to rotate the cylinder clockwise- and- counterclockwise about its longitudinal axis at selected frequencies. The particle image velocimetry （PIV） technique was used to capture the flow field behind a rotationally oscillating cylinder. Instantaneous and time-averaged flow fields such as the vorticity contours, streamline topologies and velocity distributions were analyzed. The effects of four rotation angle and frequency ratios Fr （Fr=fn/fv, the ratio of the forcing frequency fn to the natural vortex shedding frequency fv） on the wake in the lee of a rotationally oscillating cylinder were also examined. The significant wake modification was observed when the cylinder undergoes clockwise-and-counterclockwise motion with amplitude of π, especially in the range of 0.6≤Fr≤1.0.

Cu^(2+)-Catalyzed Oscillatory Oxidation of Ascorbic Acid by O_2 Flow

A novel heterogeneous oscillator, the Cu2+-catalyzed oscillatory oxidation of ascorbic acid (Vitamin C) in aqueous solution by O-2 flow was reported. Both the potential oscillations on Pt-electrode corresponding to [Cu2+] and the absorbance oscillations at lambda =260 nm corresponding to [ascorbic acid] were observed. Oscillations in the completely homogeneous system were also observed. Effects of several factors on the oscillations were investigated.