Assembly sequence planning will be more difficult due to the increasingcomplexity of products. An integrated approach to assembly sequence planning of complex productsapplying de-composition-planning-combination strat...Assembly sequence planning will be more difficult due to the increasingcomplexity of products. An integrated approach to assembly sequence planning of complex productsapplying de-composition-planning-combination strategy is presented. First, an assembly is decomposedinto a hierarchical structure using an assembly structure representation based on connectors. Then,an assembly planning system is used to generate the sequences that are locally optimal for eachleaf partition hi the structure hierarchy. By combining the local sequences systematically in abottom-up manner and choosing suitable ones from the merged sequences, the assembly sequence of eachparent structure including the whole assembly is generated. An integrated system has beencompleted. A complex product is given to illustrate the feasibility and the practicality of theapproach.展开更多
Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM...Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely展开更多
The theory of shared control combines organically the control of every controlled ele-ments and with it all the controlled elements share the same control element. Applying theschemes of shared control searched by ass...The theory of shared control combines organically the control of every controlled ele-ments and with it all the controlled elements share the same control element. Applying theschemes of shared control searched by assembly programs, an integrated control of all the ele-ments is fulfilled. The distinguishing point of the method is that the maximum control output canbe obtained with the least input information. Hence it is the optimum for the conversion of com-bination states. Finally, a thared rotary valve is designed, and it is the simplest with only onegroup of control holes.展开更多
in this paper,the statistical prOPerties of random combination sequences are discussed.Thevalue of E{R(r)}and the upper bound of E{A(r)}are derived.In the end,a new method to find a longsequence with low autocorrelati...in this paper,the statistical prOPerties of random combination sequences are discussed.Thevalue of E{R(r)}and the upper bound of E{A(r)}are derived.In the end,a new method to find a longsequence with low autocorrelation value is given.展开更多
The functionality of a gene or a protein depends on codon repeats occurring in it.As a consequence of their vitality in protein function and apparent involvement in causing diseases,an interest in these repeats has de...The functionality of a gene or a protein depends on codon repeats occurring in it.As a consequence of their vitality in protein function and apparent involvement in causing diseases,an interest in these repeats has developed in recent years.The analysis of genomic and proteomic sequences to identify such repeats requires some algorithmic support from informatics level.Here,we proposed an offline stand-alone toolkit Repeat Searcher and Motif Detector（RSMD）,which uncovers and employs few novel approaches in identification of sequence repeats and motifs to understand their functionality in sequence level and their disease causing tendency.The tool offers various features such as identifying motifs,repeats and identification of disease causing repeats.RSMD was designed to provide an easily understandable graphical user interface（GUI）,for the tool will be predominantly accessed by biologists and various researchers in all platforms of life science.GUI was developed using the scripting language Perl and its graphical module PerlTK.RSMD covers algorithmic foundations of computational biology by combining theory with practice.展开更多
基金This project is supported by National Natural Science Foundation of China (No.59990470-2).
文摘Assembly sequence planning will be more difficult due to the increasingcomplexity of products. An integrated approach to assembly sequence planning of complex productsapplying de-composition-planning-combination strategy is presented. First, an assembly is decomposedinto a hierarchical structure using an assembly structure representation based on connectors. Then,an assembly planning system is used to generate the sequences that are locally optimal for eachleaf partition hi the structure hierarchy. By combining the local sequences systematically in abottom-up manner and choosing suitable ones from the merged sequences, the assembly sequence of eachparent structure including the whole assembly is generated. An integrated system has beencompleted. A complex product is given to illustrate the feasibility and the practicality of theapproach.
基金the funds of "the Youth Fund of Nantong Health Bureau 2015",ID:WQ2015009
文摘Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely
文摘The theory of shared control combines organically the control of every controlled ele-ments and with it all the controlled elements share the same control element. Applying theschemes of shared control searched by assembly programs, an integrated control of all the ele-ments is fulfilled. The distinguishing point of the method is that the maximum control output canbe obtained with the least input information. Hence it is the optimum for the conversion of com-bination states. Finally, a thared rotary valve is designed, and it is the simplest with only onegroup of control holes.
文摘in this paper,the statistical prOPerties of random combination sequences are discussed.Thevalue of E{R(r)}and the upper bound of E{A(r)}are derived.In the end,a new method to find a longsequence with low autocorrelation value is given.
文摘The functionality of a gene or a protein depends on codon repeats occurring in it.As a consequence of their vitality in protein function and apparent involvement in causing diseases,an interest in these repeats has developed in recent years.The analysis of genomic and proteomic sequences to identify such repeats requires some algorithmic support from informatics level.Here,we proposed an offline stand-alone toolkit Repeat Searcher and Motif Detector（RSMD）,which uncovers and employs few novel approaches in identification of sequence repeats and motifs to understand their functionality in sequence level and their disease causing tendency.The tool offers various features such as identifying motifs,repeats and identification of disease causing repeats.RSMD was designed to provide an easily understandable graphical user interface（GUI）,for the tool will be predominantly accessed by biologists and various researchers in all platforms of life science.GUI was developed using the scripting language Perl and its graphical module PerlTK.RSMD covers algorithmic foundations of computational biology by combining theory with practice.
