Several equivalent statements of generalized subconvexlike set-valued map are established in ordered linear spaces. Using vector closure, we introduce Benson proper efficient solution of vector optimization problem. U...Several equivalent statements of generalized subconvexlike set-valued map are established in ordered linear spaces. Using vector closure, we introduce Benson proper efficient solution of vector optimization problem. Under the assumption of generalized subconvexlikeness, scalarization, multiplier and saddle point theorems are obtained in the sense of Benson proper efficiency.展开更多
A kind of tangent derivative and the concepts of strong and weak * pseudoconvexity for a set-valued map are introduced. By the standard separation theorems of the convex sets and cones the optimality Fritz John condit...A kind of tangent derivative and the concepts of strong and weak * pseudoconvexity for a set-valued map are introduced. By the standard separation theorems of the convex sets and cones the optimality Fritz John condition of set-valued optimization under Benson proper efficiency is established, its sufficience is discussed. The form of the optimality conditions obtained here completely tally with the classical results when the set-valued map is specialized to be a single-valued map.展开更多
In this paper,the ε-super effcient solution for set-valued map vector optimization in locally convex space is introduced.And under the assumption of the nearly generalized cone-subconvexlikeness for set-valued maps,u...In this paper,the ε-super effcient solution for set-valued map vector optimization in locally convex space is introduced.And under the assumption of the nearly generalized cone-subconvexlikeness for set-valued maps,used new methods,the scalarization theorem and Lagrange multiplier theorem for ε-super effcient solution are established.展开更多
The definitions of cone-subconvexlike set-valued maps and generalized cone-subconvexlike set-valued maps in topological vector spaces are defined by using the relative interiors of ordering cone. The relationships bet...The definitions of cone-subconvexlike set-valued maps and generalized cone-subconvexlike set-valued maps in topological vector spaces are defined by using the relative interiors of ordering cone. The relationships between the two classes of set-valued maps are investigated, and some properties of them are shown. A Gordan type alternative theorem under the assumption of generalized cone-subconvexlikeness of set-valued maps is proved by applying convex separation theorems involving the relative interiors in infinite dimensional spaces. Finally a necessary optimality condition theorem is shown for a general kind of set-valued vector optimization in a sense of weak E-minimizer.展开更多
In locally convex Hausdorff topological vector spaces,ε-strongly efficient solutions for vector optimization with set-valued maps are discussed.Firstly,ε-strongly efficient point of set is introduced.Secondly,under ...In locally convex Hausdorff topological vector spaces,ε-strongly efficient solutions for vector optimization with set-valued maps are discussed.Firstly,ε-strongly efficient point of set is introduced.Secondly,under the nearly cone-subconvexlike set-valued maps,the theorem of scalarization for vector optimization is obtained.Finally,optimality conditions of ε-strongly efficient solutions for vector optimization with generalized inequality constraints and equality constraints are obtained.展开更多
In this paper, we will construct a new class of subadditive set-valued maps and use Cantor theorem to prove that the set-valued map has an unique additive selection map when the set-valued map satisfies some certain c...In this paper, we will construct a new class of subadditive set-valued maps and use Cantor theorem to prove that the set-valued map has an unique additive selection map when the set-valued map satisfies some certain conditions, and then compare the obtained result with the well-known results.展开更多
In this paper,the dynamics(including shadowing property,expansiveness,topological stability and entropy)of several types of upper semi-continuous set-valued maps are mainly considered from differentiable dynamical sys...In this paper,the dynamics(including shadowing property,expansiveness,topological stability and entropy)of several types of upper semi-continuous set-valued maps are mainly considered from differentiable dynamical systems points of view.It is shown that(1)if f is a hyperbolic endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has theε-shadowing property,and moreover,if f is an expanding endomorphism then there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has the Lipschitz shadowing property;(2)when a set-valued map F is generated by finite expanding endomorphisms,it has the shadowing property,and moreover,if the collection of the generators has no coincidence point then F is expansive and hence is topologically stable;(3)if f is an expanding endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that h(F_(f,U,ε))=h(f);(4)when F is generated by finite expanding endomorphisms with no coincidence point,the entropy formula of F is given.Furthermore,the dynamics of the set-valued maps based on discontinuous maps on the interval are also considered.展开更多
In this paper, firstly, a new notion of generalized cone convex set-valued map is introduced in real normed spaces. Secondly, a property of the generalized cone convex set-valued map involving the contingent epideriva...In this paper, firstly, a new notion of generalized cone convex set-valued map is introduced in real normed spaces. Secondly, a property of the generalized cone convex set-valued map involving the contingent epiderivative is obtained. Finally, as the applications of this property, we use the contingent epiderivative to establish optimality conditions of the set-valued optimization problem with generalized cone convex set-valued maps in the sense of Henig proper efficiency. The results obtained in this paper generalize and improve some known results in the literature.展开更多
In this paper, we consider the following subadditive set-valued map F : X→P0(Y) :where r and s are two natural numbers. And we discuss the existence and unique problem of additive selection maps for the above set...In this paper, we consider the following subadditive set-valued map F : X→P0(Y) :where r and s are two natural numbers. And we discuss the existence and unique problem of additive selection maps for the above set-valued map.展开更多
In this paper, we discuss the unique existent problems of a additive selection map for the following map F:X→P0(Y):F(r∑i=1αixi)■r∑i=1αiF(xi),■xi∈K,i=1, ··· , r,where αi and αi (i = 1, ·...In this paper, we discuss the unique existent problems of a additive selection map for the following map F:X→P0(Y):F(r∑i=1αixi)■r∑i=1αiF(xi),■xi∈K,i=1, ··· , r,where αi and αi (i = 1, ··· , r) are all non-negative real numbers.展开更多
This paper deals with higher-order optimality conditions for Henig effcient solutions of set-valued optimization problems.By virtue of the higher-order tangent sets, necessary and suffcient conditions are obtained for...This paper deals with higher-order optimality conditions for Henig effcient solutions of set-valued optimization problems.By virtue of the higher-order tangent sets, necessary and suffcient conditions are obtained for Henig effcient solutions of set-valued optimization problems whose constraint condition is determined by a fixed set.展开更多
In complete metric spaces, the common fixed point theorems for sequences of φ-type contraction set-valued mappings are established, and the corresponding random com- mon fixed point theorems for set-valued mappings a...In complete metric spaces, the common fixed point theorems for sequences of φ-type contraction set-valued mappings are established, and the corresponding random com- mon fixed point theorems for set-valued mappings are also obtained.展开更多
In this paper,we study the value distribution properties of the generalized Gauss maps of weakly complete harmonic surfaces immersed in R^(m),which is the case where the generalized Gauss mapΦis ramified over a famil...In this paper,we study the value distribution properties of the generalized Gauss maps of weakly complete harmonic surfaces immersed in R^(m),which is the case where the generalized Gauss mapΦis ramified over a family of hypersurfaces{Q_(j)}_(j=1)^(q)in P^(m-1)(C)located in the N-subgeneral position.In addition,we investigate the Gauss curvature estimate for the K-quasiconformal harmonic surfaces immersed in R^(3)whose Gauss maps are ramified over a family of hypersurfaces located in the N-subgeneral position.展开更多
This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signa...This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signals and degrade positioning accuracy.Managed by the Indonesian Geospatial Information Agency(BIG),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 GNSS receivers spanning equatorial to southern low-latitude regions.Ina-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast Asia.We provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this network.We generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific research.Two preliminary findings from the ROTI maps of Ina-CORS are noteworthy.First,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther eastward.Second,we demonstrate that combined ROTI maps from Ina-CORS and GNSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East Asia.We have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the G5 Geomagnetic Storm on May 11,2024.We observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities post-midnight.By sharing ROTI maps from Indonesia and integrating them with regional GNSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionospheric research.展开更多
In this paper,we consider pseudoharmonic heat flow with small initial horizontal energy and give the existence of pseudoharmonic maps from closed pseudo-Hermitian manifolds into closed Riemannian manifolds.
We introduced a new class of fuzzy set-valued variational inclusions with (H,η)-monotone mappings. Using the resolvent operator method in Hilbert spaces, we suggested a new proximal point algorithm for finding approx...We introduced a new class of fuzzy set-valued variational inclusions with (H,η)-monotone mappings. Using the resolvent operator method in Hilbert spaces, we suggested a new proximal point algorithm for finding approximate solutions, which strongly converge to the exact solution of a fuzzy set-valued variational inclusion with (H,η)-monotone. The results improved and generalized the general quasi-variational inclusions with fuzzy set-valued mappings proposed by Jin and Tian Jin MM, Perturbed proximal point algorithm for general quasi-variational inclusions with fuzzy set-valued mappings, OR Transactions, 2005, 9(3): 31-38, (In Chinese); Tian YX, Generalized nonlinear implicit quasi-variational inclusions with fuzzy mappings, Computers & Mathematics with Applications, 2001, 42: 101-108.展开更多
Formal concept analysis (FCA) is a discipline that studied the hierarchical structures induced by a binary relation between a pair of sets, and applies in data analysis, information retrieval, knowledge discovery, e...Formal concept analysis (FCA) is a discipline that studied the hierarchical structures induced by a binary relation between a pair of sets, and applies in data analysis, information retrieval, knowledge discovery, etc. In this paper, it is shown that a formal context T is equivalent to a set-valued mapping S : G → P(М), and formal concepts could be defined in the set-valued mapping S. It is known that the topology and set-valued mapping are linked. Hence, the advantage of this paper is that the conclusion make us to construct formal concept lattice based on the topology.展开更多
In this paper,we first give the general forms of skew commuting maps and skew anti-commuting maps by the Peirce decomposition on a unital ring with a nontrivial idempotent,respectively,and then,as applications,we obta...In this paper,we first give the general forms of skew commuting maps and skew anti-commuting maps by the Peirce decomposition on a unital ring with a nontrivial idempotent,respectively,and then,as applications,we obtain the concrete characterizations of all nonadditive skew(anti-)commuting maps on some operator algebras.展开更多
BACKGROUND Although surgery remains the primary treatment for gastric cancer(GC),the identification of effective alternative treatments for individuals for whom surgery is unsuitable holds significance.HER2 overexpres...BACKGROUND Although surgery remains the primary treatment for gastric cancer(GC),the identification of effective alternative treatments for individuals for whom surgery is unsuitable holds significance.HER2 overexpression occurs in approximately 15%-20%of advanced GC cases,directly affecting treatment-related decisions.Spectral-computed tomography(sCT)enables the quantification of material compositions,and sCT iodine concentration parameters have been demonstrated to be useful for the diagnosis of GC and prediction of its invasion depth,angioge-nesis,and response to systemic chemotherapy.No existing report describes the prediction of GC HER2 status through histogram analysis based on sCT iodine maps(IMs).AIM To investigate whether whole-volume histogram analysis of sCT IMs enables the prediction of the GC HER2 status.METHODS This study was performed with data from 101 patients with pathologically confirmed GC who underwent preoperative sCT examinations.Nineteen parameters were extracted via sCT IM histogram analysis:The minimum,maximum,mean,standard deviation,variance,coefficient of variation,skewness,kurtosis,entropy,percentiles(1st,5th,10th,25th,50th,75th,90th,95th,and 99th),and lesion volume.Spearman correlations of the parameters with the HER2 status and clinicopathological parameters were assessed.Receiver operating characteristic curves were used to evaluate the parameters’diagnostic performance.RESULTS Values for the histogram parameters of the maximum,mean,standard deviation,variance,entropy,and percentiles were significantly lower in the HER2+group than in the HER2–group(all P<0.05).The GC differentiation and Lauren classification correlated significantly with the HER2 status of tumor tissue(P=0.001 and 0.023,respectively).The 99th percentile had the largest area under the curve for GC HER2 status identification(0.740),with 76.2%,sensitivity,65.0%specificity,and 67.3%accuracy.All sCT IM histogram parameters correlated positively with the GC HER2 status(r=0.237-0.337,P=0.001-0.017).CONCLUSION Whole-lesion histogram parameters derived from sCT IM analysis,and especially the 99th percentile,can serve as imaging biomarkers of HER2 overexpression in GC.展开更多
文摘Several equivalent statements of generalized subconvexlike set-valued map are established in ordered linear spaces. Using vector closure, we introduce Benson proper efficient solution of vector optimization problem. Under the assumption of generalized subconvexlikeness, scalarization, multiplier and saddle point theorems are obtained in the sense of Benson proper efficiency.
文摘A kind of tangent derivative and the concepts of strong and weak * pseudoconvexity for a set-valued map are introduced. By the standard separation theorems of the convex sets and cones the optimality Fritz John condition of set-valued optimization under Benson proper efficiency is established, its sufficience is discussed. The form of the optimality conditions obtained here completely tally with the classical results when the set-valued map is specialized to be a single-valued map.
基金Supported by the Natural Science Foundation of the Education Department of Henan Province(2004110008)
文摘In this paper,the ε-super effcient solution for set-valued map vector optimization in locally convex space is introduced.And under the assumption of the nearly generalized cone-subconvexlikeness for set-valued maps,used new methods,the scalarization theorem and Lagrange multiplier theorem for ε-super effcient solution are established.
文摘The definitions of cone-subconvexlike set-valued maps and generalized cone-subconvexlike set-valued maps in topological vector spaces are defined by using the relative interiors of ordering cone. The relationships between the two classes of set-valued maps are investigated, and some properties of them are shown. A Gordan type alternative theorem under the assumption of generalized cone-subconvexlikeness of set-valued maps is proved by applying convex separation theorems involving the relative interiors in infinite dimensional spaces. Finally a necessary optimality condition theorem is shown for a general kind of set-valued vector optimization in a sense of weak E-minimizer.
基金Foundation item: Supported by the Natural Science Foundation of China(10871216) Supported by the Natural Science Foundation Project of CQ CSTC(2008BB0346, 2007BB0441) Supported by the Excellent Young Teachers Program of Chongqing Jiaotong University(EYT08-016) Acknowledgement The author would like to thank the anonymous referee for the valuable remarks that helped considerably to correct and to improve the presentation.
文摘In locally convex Hausdorff topological vector spaces,ε-strongly efficient solutions for vector optimization with set-valued maps are discussed.Firstly,ε-strongly efficient point of set is introduced.Secondly,under the nearly cone-subconvexlike set-valued maps,the theorem of scalarization for vector optimization is obtained.Finally,optimality conditions of ε-strongly efficient solutions for vector optimization with generalized inequality constraints and equality constraints are obtained.
基金Supported by the National Natural Science Foundation of China(11361064)
文摘In this paper, we will construct a new class of subadditive set-valued maps and use Cantor theorem to prove that the set-valued map has an unique additive selection map when the set-valued map satisfies some certain conditions, and then compare the obtained result with the well-known results.
文摘In this paper,the dynamics(including shadowing property,expansiveness,topological stability and entropy)of several types of upper semi-continuous set-valued maps are mainly considered from differentiable dynamical systems points of view.It is shown that(1)if f is a hyperbolic endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has theε-shadowing property,and moreover,if f is an expanding endomorphism then there exists a C^(1)-neighborhood U of f such that the induced set-valued map F_(f,U)has the Lipschitz shadowing property;(2)when a set-valued map F is generated by finite expanding endomorphisms,it has the shadowing property,and moreover,if the collection of the generators has no coincidence point then F is expansive and hence is topologically stable;(3)if f is an expanding endomorphism then for eachε>0 there exists a C^(1)-neighborhood U of f such that h(F_(f,U,ε))=h(f);(4)when F is generated by finite expanding endomorphisms with no coincidence point,the entropy formula of F is given.Furthermore,the dynamics of the set-valued maps based on discontinuous maps on the interval are also considered.
基金supported by the National Nature Science Foundation of China(11431004,11471291)the General Project of Chongqing Frontier and Applied Foundation Research(cstc2015jcyj A00050)the Key Project of Chongqing Frontier and Applied Foundation Research(cstc2017jcyj BX0055,cstc2015jcyj BX0113)
文摘In this paper, firstly, a new notion of generalized cone convex set-valued map is introduced in real normed spaces. Secondly, a property of the generalized cone convex set-valued map involving the contingent epiderivative is obtained. Finally, as the applications of this property, we use the contingent epiderivative to establish optimality conditions of the set-valued optimization problem with generalized cone convex set-valued maps in the sense of Henig proper efficiency. The results obtained in this paper generalize and improve some known results in the literature.
基金Supported by Science Foundation of Education Committee of Jilin Province of China([2011]No.434)
文摘In this paper, we consider the following subadditive set-valued map F : X→P0(Y) :where r and s are two natural numbers. And we discuss the existence and unique problem of additive selection maps for the above set-valued map.
基金Foundation item: Supported by the Science Foundation of Education Committee of Jilin Province([2011] No434)
文摘In this paper, we discuss the unique existent problems of a additive selection map for the following map F:X→P0(Y):F(r∑i=1αixi)■r∑i=1αiF(xi),■xi∈K,i=1, ··· , r,where αi and αi (i = 1, ··· , r) are all non-negative real numbers.
基金Supported by the National Natural Science Foundation of China(10871216) Supported by the Science and Technology Research Project of Chongqing Municipal Education Commission(KJ100419) Supported by the Natural Science Foundation Project of CQ CSTC(cstcjjA00019)
文摘This paper deals with higher-order optimality conditions for Henig effcient solutions of set-valued optimization problems.By virtue of the higher-order tangent sets, necessary and suffcient conditions are obtained for Henig effcient solutions of set-valued optimization problems whose constraint condition is determined by a fixed set.
基金Foundation item: Supported by the Science Foundation from the Ministry of Education of Jiangsu Province(04KJD110168, 06KJBll0107)
文摘In complete metric spaces, the common fixed point theorems for sequences of φ-type contraction set-valued mappings are established, and the corresponding random com- mon fixed point theorems for set-valued mappings are also obtained.
基金supported by the NFSC(11971182,12271189)the NFS of Fujian Province of China(2019J01066,2021J01304)。
文摘In this paper,we study the value distribution properties of the generalized Gauss maps of weakly complete harmonic surfaces immersed in R^(m),which is the case where the generalized Gauss mapΦis ramified over a family of hypersurfaces{Q_(j)}_(j=1)^(q)in P^(m-1)(C)located in the N-subgeneral position.In addition,we investigate the Gauss curvature estimate for the K-quasiconformal harmonic surfaces immersed in R^(3)whose Gauss maps are ramified over a family of hypersurfaces located in the N-subgeneral position.
基金JSPS KAKENHI Grant Number16H06286 supports global GNSS ionospheric maps (TEC,ROTI,and detrended TEC maps) developed by the Institute for SpaceEarth Environmental Research (ISEE) of Nagoya Universitysupport of the 2024 JASSO Follow-up Research Fellowship Program for a 90-day visiting research at the Institute for Space-Earth Environmental Research (ISEE),Nagoya University+3 种基金the support received from Telkom University under the“Skema Penelitian Terapan Periode I Tahun Anggaran 2024”the Memorandum of Understanding for Research Collaboration on Regional Ionospheric Observation (No:092/SAM3/TE-DEK/2021)the National Institute of Information and Communications Technology (NICT) International Exchange Program 2024-2025(No.2024-007)support for a one-year visiting research at Hokkaido University
文摘This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signals and degrade positioning accuracy.Managed by the Indonesian Geospatial Information Agency(BIG),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 GNSS receivers spanning equatorial to southern low-latitude regions.Ina-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast Asia.We provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this network.We generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific research.Two preliminary findings from the ROTI maps of Ina-CORS are noteworthy.First,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther eastward.Second,we demonstrate that combined ROTI maps from Ina-CORS and GNSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East Asia.We have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the G5 Geomagnetic Storm on May 11,2024.We observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities post-midnight.By sharing ROTI maps from Indonesia and integrating them with regional GNSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionospheric research.
文摘In this paper,we consider pseudoharmonic heat flow with small initial horizontal energy and give the existence of pseudoharmonic maps from closed pseudo-Hermitian manifolds into closed Riemannian manifolds.
基金the Natural Science Foundation of China (No. 10471151)the Educational Science Foundation of Chongqing (KJ051307).
文摘We introduced a new class of fuzzy set-valued variational inclusions with (H,η)-monotone mappings. Using the resolvent operator method in Hilbert spaces, we suggested a new proximal point algorithm for finding approximate solutions, which strongly converge to the exact solution of a fuzzy set-valued variational inclusion with (H,η)-monotone. The results improved and generalized the general quasi-variational inclusions with fuzzy set-valued mappings proposed by Jin and Tian Jin MM, Perturbed proximal point algorithm for general quasi-variational inclusions with fuzzy set-valued mappings, OR Transactions, 2005, 9(3): 31-38, (In Chinese); Tian YX, Generalized nonlinear implicit quasi-variational inclusions with fuzzy mappings, Computers & Mathematics with Applications, 2001, 42: 101-108.
基金the Young Foundation of Sichuan Province(06ZQ026-037) the Education Department Foundation of Sichuan Province(2005A1212006A084)
文摘Formal concept analysis (FCA) is a discipline that studied the hierarchical structures induced by a binary relation between a pair of sets, and applies in data analysis, information retrieval, knowledge discovery, etc. In this paper, it is shown that a formal context T is equivalent to a set-valued mapping S : G → P(М), and formal concepts could be defined in the set-valued mapping S. It is known that the topology and set-valued mapping are linked. Hence, the advantage of this paper is that the conclusion make us to construct formal concept lattice based on the topology.
基金supported by the National Natural Science Foundation of China (Nos.12171290,12301152)the Natural Science Foundation of Shanxi Province (No.202203021222018)。
文摘In this paper,we first give the general forms of skew commuting maps and skew anti-commuting maps by the Peirce decomposition on a unital ring with a nontrivial idempotent,respectively,and then,as applications,we obtain the concrete characterizations of all nonadditive skew(anti-)commuting maps on some operator algebras.
基金Supported by Science and Technology Program of Fujian Province,No.2021J01430Joint Funds for the Innovation of Science and Technology of Fujian Province,No.2021Y9229.
文摘BACKGROUND Although surgery remains the primary treatment for gastric cancer(GC),the identification of effective alternative treatments for individuals for whom surgery is unsuitable holds significance.HER2 overexpression occurs in approximately 15%-20%of advanced GC cases,directly affecting treatment-related decisions.Spectral-computed tomography(sCT)enables the quantification of material compositions,and sCT iodine concentration parameters have been demonstrated to be useful for the diagnosis of GC and prediction of its invasion depth,angioge-nesis,and response to systemic chemotherapy.No existing report describes the prediction of GC HER2 status through histogram analysis based on sCT iodine maps(IMs).AIM To investigate whether whole-volume histogram analysis of sCT IMs enables the prediction of the GC HER2 status.METHODS This study was performed with data from 101 patients with pathologically confirmed GC who underwent preoperative sCT examinations.Nineteen parameters were extracted via sCT IM histogram analysis:The minimum,maximum,mean,standard deviation,variance,coefficient of variation,skewness,kurtosis,entropy,percentiles(1st,5th,10th,25th,50th,75th,90th,95th,and 99th),and lesion volume.Spearman correlations of the parameters with the HER2 status and clinicopathological parameters were assessed.Receiver operating characteristic curves were used to evaluate the parameters’diagnostic performance.RESULTS Values for the histogram parameters of the maximum,mean,standard deviation,variance,entropy,and percentiles were significantly lower in the HER2+group than in the HER2–group(all P<0.05).The GC differentiation and Lauren classification correlated significantly with the HER2 status of tumor tissue(P=0.001 and 0.023,respectively).The 99th percentile had the largest area under the curve for GC HER2 status identification(0.740),with 76.2%,sensitivity,65.0%specificity,and 67.3%accuracy.All sCT IM histogram parameters correlated positively with the GC HER2 status(r=0.237-0.337,P=0.001-0.017).CONCLUSION Whole-lesion histogram parameters derived from sCT IM analysis,and especially the 99th percentile,can serve as imaging biomarkers of HER2 overexpression in GC.