Give Full Play the Role of Traditional Chinese Medicine to Prevent and Treat Severe Acute Respiratory Syndrome with Integrative Chinese and Western Medicine Approach

Member of Political Bureau of Central Committee of CPC, Vice Premier of State Council concurrently Minister of Health, General Command of National Protecting and Treating Severe Acute Respiratory Syndrome ( SARS) Headquarters Vice premier WU Yi cordially met the well-known TCM specialists, and held a symposium with them. Sixteen specialists including WANG Yong-yan, CHEN Ke-ji, LI Fu-ren, JIAO Shu-de, HE Pu-ren, LIU

Combined Use of Chinese Medicine with Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia Patients

Objective：To determine the effect of combined treatment with Chinese medicine（CM） and allogeneic hematopoietic stem ceil transplantation（allo-HSCT） on patients with severe aplastic anemia（SAA）.Methods：Eleven patients were treated with CM plus ailo-HSCT.Nine patients received a conditioning regimen consisting of fludarabine（Flu）,anti-thymocyte globulin（pig ALG）,or anti-lymphocyte globulin（Rabbit ATG） and cyclophosphamide（CY）,and two patients received pig ALG and CY.All patients were treated with Kidney（Shen）-reinforcing,blood-activating,and stasis-removing（KBS） herbal preparation beginning at 1 week before transplantation and ending at 8 weeks after transplantation.Chimerism status was assessed by analyzing short tandem repeat（STR） polymorphisms.Results：All patients recovered hematopoietic function and none had graft failure.The median number of days required for the absolute neutrophil count（ANC） increased to 〉0.5× 10~9/L was 15 days（12-22 days） and for spontaneous platelet recovery to 〉20×10~9/L without post-transplantation transfusion was 17 days（15-27 days）.Nine patients were longterm survivors and achieved full donor chimerism.The overall cumulative incidence of acute graft versus host disease（GVHD） grades Ⅰ-Ⅱ and Ⅲ-Ⅳ was 18.2%（2/11） and 9.1%（1 /11）,respectively.The overall accumulated incidence of chronic GVHD was 27.3%and all patients had limited chronic GVHD.At a median follow-up time of 32 months（range：12-97 months）,9 patients were still alive.The estimated 5-year overall survival（OS） rate was 81.8%.The incidence of treatment-related mortality,2-year post-transplantation,was 18.2%.Two patients died from GVHD after transplantation.Conclusion：Treatment with the KBS formulation may reduce the rate of graft failure and treatmentrelated mortality and improve the rate of OS in SAA patients with allo-HSCT.

Successful Treatment with Integrated Chinese and Western Medicine for Severe Overdose of Amlodipine:A Case Report

Introduction Amlodipine is a dihydropyridine calcium channel blocker （CCB） that inhibits calcium influx into cardiac, vascular smooth muscle cells, and pancreatic beta cells, leading to dilation of arteries and arterioles and reduction in insulin secretion. Oral administration of amlodipine is absorbed slowly but almost completely, with a hiah oral bioavailabilitv up to 60%-80%.