The transports of the dynamic biochemical signals in the non-reversing pulsatile flows in the mixing microchannel of a Y-shaped microfluidic device are ana- lyzed. The results show that the mixing micro-channel acts a...The transports of the dynamic biochemical signals in the non-reversing pulsatile flows in the mixing microchannel of a Y-shaped microfluidic device are ana- lyzed. The results show that the mixing micro-channel acts as a low-pass filter, and the biochemical signals are nonlinearly modulated by the pulsatile flows, which depend on the biochemical signal frequency, the flow signal frequency, and the biochemical signal transporting distance. It is concluded that, the transfer characteristics of the dynamic biochemical signals, which are transported in the time-varying flows, should be carefully considered for better loading biochemical signals on the cells cultured on the bottom of the microfluidic channel.展开更多
This paper presents an analysis of dispersion of dynamic biochemical signals in steady flow in a shallow Y-type microfluidic channel. A method is presented to control the flow widths of two steady flows in the Y-type ...This paper presents an analysis of dispersion of dynamic biochemical signals in steady flow in a shallow Y-type microfluidic channel. A method is presented to control the flow widths of two steady flows in the Y-type microchannel from two inlets.The transfer function for the Y-type microchannel is given by solving the governing equation for the Taylor-Aris dispersion in the microchannel. The amplitude-frequency and phase-frequency relations are provided which show that a shallow Y-type microchannel acts as a low-pass filter. The transports of different dynamic biochemical signals are investigated. In comparison with a fully mixing microfluidic channel, the magnitudes of the dynamic signals at the outlets in a Y-type microchannel are much smaller than those in a fully mixing microchannel, which demonstrates that the amplitude attenuation in a Y-type microchannel is larger than that of a fully mixing microchannel due to the transverse molecular diffusion. In order to control the desired signal in a microchannel, the solution of the inverse problem for the channel is also presented.展开更多
Quaternary buried ancient river channels are widespread in the shallow-level sediments of the northern shelf of the South China Sea. The sedimentary sequence mainly of fluvial deposits comprise an important component ...Quaternary buried ancient river channels are widespread in the shallow-level sediments of the northern shelf of the South China Sea. The sedimentary sequence mainly of fluvial deposits comprise an important component part of the low-stand system tract and transgressive system tract in the study region. The plannar variation and spatial association of the sedimentary features such as incised valley fillings, deltaic foreset wedges and block slides of shelf-marginal fans reflect the palaeogeographic environment during the fall of the regional sea level in the northern part of the South China Sea. Based on the high-resolution seismic reflection data and gelogical data from boreholes, the present paper makes an integrated interpretation of the Quaternary ancient river channels in the shallow sediments of the study area, studies the sedimentary features of the ancient channels such as their spatial distribution, seismic facies reflection indicators, sedimentary facies and sand -body types, and discusses their formational setting and evolutionary model, with the main purpose to render a service to the hydrocarbon resources exploration and development and marine engineering in the northern shelf of the South China Sea.展开更多
浅水流(Shallow Water Flow,SWF)是深水环境海底浅部地层中超压的砂体流动,是对深水钻井最具破坏力的一种地质灾害,严重制约深水油气开发.为有效预测和防治浅水流,需要对浅水流地球物理特性进行研究,并在研究区内加以识别.本文借鉴国外...浅水流(Shallow Water Flow,SWF)是深水环境海底浅部地层中超压的砂体流动,是对深水钻井最具破坏力的一种地质灾害,严重制约深水油气开发.为有效预测和防治浅水流,需要对浅水流地球物理特性进行研究,并在研究区内加以识别.本文借鉴国外主要深水盆地对浅水流问题的研究经验,对南海北部深水盆地潜在浅水流区域采取以属性判定、超压分析为主,振幅识别为辅的方法进行预测.精细层序地层学解释发现,南海北部深水盆地存在上新世以来的古珠江深水水道沉积体系和第四纪水道,这些水道砂体疏松未固结、孔隙度大、有效应力低、几乎表现出流体特性.基于遗传算法的混合反演方法发现,研究区存在典型的AVO响应,横波速度极低,低频特征明显,振幅强度弱,连续性较好,存在极性反转,高泊白松比和高纵横波速度比.研究结果表明,南海北部陆坡具备浅水流发生的潜在条件,深水水道发育区为潜在的浅水流危险区,浅水流具有独特的地震响应特征,泊松比高达0.49,纵横波速度比约为3.5~9或更高,SWF层位对地震属性的敏感度V_P/V_S>AVO响应>泊松比.展开更多
Focusing on the design problem of high-performance radiators for planar motors in the wafer stage of the lithography machine,a thermal-fluid coupling optimization scheme based on parametric solid components was propos...Focusing on the design problem of high-performance radiators for planar motors in the wafer stage of the lithography machine,a thermal-fluid coupling optimization scheme based on parametric solid components was proposed.The mapping method between component parameters and pseudo-density values was established.An analytical solution for the sensitivity of pseudo-density to component parameters was given.The conjugate heat transfer function with the shallow channel approximation term was solved through the pseudo-density information.In the optimization example,circular components were selected,and the position and the size of solid components were chosen as design variables.In order to eliminate calculation errors caused by pseudo-density,an optimized pseudo-density field was converted into the result based on parametric components.Compared to the reference motor radiator,the average surface temperature rise of the optimized water-cooling motor radiator is reduced by 22.4%,which verifies the feasibility and effectiveness of the proposed method.展开更多
Input/output devices for flash memory are exposed to gamma ray irradiation. Total ionizing dose has been shown great influence on characteristic degradation of transistors with different sizes. In this paper, we obser...Input/output devices for flash memory are exposed to gamma ray irradiation. Total ionizing dose has been shown great influence on characteristic degradation of transistors with different sizes. In this paper, we observed a larger increase of off-state leakage in the short channel device than in long one. However, a larger threshold voltage shift is observed for the narrow width device than for the wide one, which is well known as the radiation induced narrow channel effect. The radiation induced charge in the shallow trench isolation oxide influences the electric field of the narrow channel device. Also, the drain bias dependence of the off-state leakage after irradiation is observed, which is called the radiation enhanced drain induced barrier lowing effect. Finally, we found that substrate bias voltage can suppress the off-state leakage, while leading to more obvious hump effect.展开更多
基金Project supported by the National Natural Science Foundation of China(Nos.11172060 and11672065)
文摘The transports of the dynamic biochemical signals in the non-reversing pulsatile flows in the mixing microchannel of a Y-shaped microfluidic device are ana- lyzed. The results show that the mixing micro-channel acts as a low-pass filter, and the biochemical signals are nonlinearly modulated by the pulsatile flows, which depend on the biochemical signal frequency, the flow signal frequency, and the biochemical signal transporting distance. It is concluded that, the transfer characteristics of the dynamic biochemical signals, which are transported in the time-varying flows, should be carefully considered for better loading biochemical signals on the cells cultured on the bottom of the microfluidic channel.
基金National Natural Science Foundation of Chinagrant number:11172060the Fundamental Research Funds for the Central Universities in China
文摘This paper presents an analysis of dispersion of dynamic biochemical signals in steady flow in a shallow Y-type microfluidic channel. A method is presented to control the flow widths of two steady flows in the Y-type microchannel from two inlets.The transfer function for the Y-type microchannel is given by solving the governing equation for the Taylor-Aris dispersion in the microchannel. The amplitude-frequency and phase-frequency relations are provided which show that a shallow Y-type microchannel acts as a low-pass filter. The transports of different dynamic biochemical signals are investigated. In comparison with a fully mixing microfluidic channel, the magnitudes of the dynamic signals at the outlets in a Y-type microchannel are much smaller than those in a fully mixing microchannel, which demonstrates that the amplitude attenuation in a Y-type microchannel is larger than that of a fully mixing microchannel due to the transverse molecular diffusion. In order to control the desired signal in a microchannel, the solution of the inverse problem for the channel is also presented.
基金The present paper represents the result of a scientific research subject of the UNDP-assisted Project "Marine Engineering Geological Investigation of the Pearl River Mouth Basin in the Northern Party of the South China Sea" (Project No. UNDP.CPR/85/044)
文摘Quaternary buried ancient river channels are widespread in the shallow-level sediments of the northern shelf of the South China Sea. The sedimentary sequence mainly of fluvial deposits comprise an important component part of the low-stand system tract and transgressive system tract in the study region. The plannar variation and spatial association of the sedimentary features such as incised valley fillings, deltaic foreset wedges and block slides of shelf-marginal fans reflect the palaeogeographic environment during the fall of the regional sea level in the northern part of the South China Sea. Based on the high-resolution seismic reflection data and gelogical data from boreholes, the present paper makes an integrated interpretation of the Quaternary ancient river channels in the shallow sediments of the study area, studies the sedimentary features of the ancient channels such as their spatial distribution, seismic facies reflection indicators, sedimentary facies and sand -body types, and discusses their formational setting and evolutionary model, with the main purpose to render a service to the hydrocarbon resources exploration and development and marine engineering in the northern shelf of the South China Sea.
文摘浅水流(Shallow Water Flow,SWF)是深水环境海底浅部地层中超压的砂体流动,是对深水钻井最具破坏力的一种地质灾害,严重制约深水油气开发.为有效预测和防治浅水流,需要对浅水流地球物理特性进行研究,并在研究区内加以识别.本文借鉴国外主要深水盆地对浅水流问题的研究经验,对南海北部深水盆地潜在浅水流区域采取以属性判定、超压分析为主,振幅识别为辅的方法进行预测.精细层序地层学解释发现,南海北部深水盆地存在上新世以来的古珠江深水水道沉积体系和第四纪水道,这些水道砂体疏松未固结、孔隙度大、有效应力低、几乎表现出流体特性.基于遗传算法的混合反演方法发现,研究区存在典型的AVO响应,横波速度极低,低频特征明显,振幅强度弱,连续性较好,存在极性反转,高泊白松比和高纵横波速度比.研究结果表明,南海北部陆坡具备浅水流发生的潜在条件,深水水道发育区为潜在的浅水流危险区,浅水流具有独特的地震响应特征,泊松比高达0.49,纵横波速度比约为3.5~9或更高,SWF层位对地震属性的敏感度V_P/V_S>AVO响应>泊松比.
基金Supported by the National Natural Science Foundation of China(51677104)。
文摘Focusing on the design problem of high-performance radiators for planar motors in the wafer stage of the lithography machine,a thermal-fluid coupling optimization scheme based on parametric solid components was proposed.The mapping method between component parameters and pseudo-density values was established.An analytical solution for the sensitivity of pseudo-density to component parameters was given.The conjugate heat transfer function with the shallow channel approximation term was solved through the pseudo-density information.In the optimization example,circular components were selected,and the position and the size of solid components were chosen as design variables.In order to eliminate calculation errors caused by pseudo-density,an optimized pseudo-density field was converted into the result based on parametric components.Compared to the reference motor radiator,the average surface temperature rise of the optimized water-cooling motor radiator is reduced by 22.4%,which verifies the feasibility and effectiveness of the proposed method.
文摘Input/output devices for flash memory are exposed to gamma ray irradiation. Total ionizing dose has been shown great influence on characteristic degradation of transistors with different sizes. In this paper, we observed a larger increase of off-state leakage in the short channel device than in long one. However, a larger threshold voltage shift is observed for the narrow width device than for the wide one, which is well known as the radiation induced narrow channel effect. The radiation induced charge in the shallow trench isolation oxide influences the electric field of the narrow channel device. Also, the drain bias dependence of the off-state leakage after irradiation is observed, which is called the radiation enhanced drain induced barrier lowing effect. Finally, we found that substrate bias voltage can suppress the off-state leakage, while leading to more obvious hump effect.