“Between Heaven and Earth” Scientific Basis of the Action of Shao Yin: Lightning’s Physical-Mathematical Analysis

In an analytic methodological approach, TCM Shao Yin circuit and Lightning physics are compared in order to provide an academic support to relate these phenomena. The aim of this work is to offer a scientific description contrasting both events, so to find an electrophysiological explanation for the complementary resuscitation maneuver over K-1 Yongquan acupuncture point.

Effects of Dan-shao-hua-xian on expression of PPAR-gamma and NF-kappa B in rat liver fibrosis

BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPAR-gamma) and nuclear factor kappa B (NF-kappa B) play important roles in liver fibrosis. This study aimed to investigate the effects of Dan-shao-hua-xian, a preparation of traditional Chinese medicine, on the expression of PPAR-gamma and NF-kappa B in the fibrotic livers of rats. METHODS: Seventy Wistar rats were randomly divided into 4 groups: treatment (model, 8 weeks+treatment, 8 weeks; group A), natural recovery (model, 8 weeks+ saline, 8 weeks; group B), model (model only, 8 weeks; group Q, and control (normal, untreated, 16 weeks; group D). Each group consisted of 20 rats (except for group D, which had 10). Fibrotic liver models were induced in rats by subcutaneous injection of CCI4, oral administration of alcohol and a high-lipid/low-protein diet for 8 weeks. After the models were established, the rats in group A were orally given Dan-shao-hua-xian capsules daily for another 8 weeks. Then, the liver indices serum hyaluronic acid (HA), tumor necrosis factor-alpha (TNF-alpha) and alanine aminotransferase (ALT) were measured. The degree of hepatic fibrosis was evaluated by optical microscopy. Hydroxyproline (Hyp) in the liver tissue was determined. The expression of PPAR-gamma was detected by immunohistochemical techniques. The protein levels of PPAR-gamma and NF-kappa B were determined by Western blotting. RESULTS: The concentrations of serum HA, TNF-alpha and Hyp in group C increased compared with group D (P<0.05), and they decreased in group A compared with group C (P<0.05). The expression of PPAR-gamma in group C decreased compared with group D (P<0.05), and it increased in group A compared with groups B and C (P<0.05). Similarly, Western blotting showed that the expression of PPAR-gamma in group C decreased compared with group D, and it increased in group A compared with group C. The expression of NF-kappa B increased in group C compared with group D (P<0.05), and it decreased in group A compared with group C (P<0.05). CONCLUSION: Dan-shao-hua-xian capsules enhance the expression of PPAR-gamma but decrease that of TNF-alpha and NF-kappa B in the liver tissues of CCI4-induced hepatic fibrotic rats. These effects may play a role in its activity in treating hepatic fibrosis.

Network Pharmacology-based Analysis of the Mechanism of Action of the Herb Pair Chai Hu-Bai Shao

Objective To analyze the mechanism of action and compatibility of the active compounds of the traditional herb pair Bupleuri Radix(Chai Hu,CH,柴胡)-Paeoniae Radix Alba(Bai Shao,BS,白芍).Methods All chemical compounds related to CH and BS were retrieved from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP),Traditional Chinese Medicine Integrated Database(TCMID),Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine(Batman-TCM),Traditional Chinese Medicine Database@Taiwan(TCM Database@Taiwan),and the literature.Relevant compounds were screened for oral bioavailability(OB),drug-likeness(DL),and the Caco-2 cell model.The Uniprot,Genecard,and CTD databases were used to obtain information on potential targets and diseases of associated compounds.Based on this,Cytoscape 3.2.1 software,GO enrichment analysis,and KEGG pathway enrichment were used to analyze the potential mechanism of action and pathways of the CH-BS drug combination.Results A total of 23 active compounds of CH and BS were indentified after meeting specific criteria by network pharmacology,showing 79 predicted targets of active compounds.Among them,all targets were associated with 344 diseases,and the compounds in CH and BS were connected to 94 pathways and biological,such as calcium signaling pathway,neuroactive ligand-receptor interaction and TNF signaling pathway.Conclusions Our results preliminarily validated the main compounds in CH-BS herb pair interacted with multiple targets in different diseases,and the molecular mechanism of these compounds involves multiple pathways,thereby establishing a good foundation for further studies.

Chinese Four Big Forests of Steles——by our staff reporter Shao De

The chinese upright stone tablets started building early inQindynasty which were called stone-carving in the Initial stage.After the Eastern Han Dynasty, they were gradually changed name as"tablets" or "steles" with the increasing of carved stones. Greatnumbers of stone tablets standing like trees in forest, were later

Experience of Professor Shao Mingxi in treating knee osteoarthritis based on "Bin Si Xue" acupuncture

Objective: To introduce the clinical experience and treatment characteristics of Professor Shao Mingxi's acupuncture penetrating "Four Four Points" to treat knee osteoarthritis. Methods:By following the teacher's professor Shao Mingxi, he should learn to pierce "Four Points", collect their test cases for the diagnosis and treatment of knee osteoarthritis, and summarize their diagnosis and treatment experience and clinical characteristics. Results: The method of Professor Shao Ming-Xi's "Bin Si Xue" connected with four fingers push in treatment of knee osteoarthritis is notably effective. Conclusions: Professor Shao Mingxi's unique experience in treating knee osteoarthritis with acupuncture needles at "Four Points" The effect is remarkable, and the preliminary summary is summarized to inherit the experience of famous old Chinese medicine.

Shao Steel Products

The Guangdong Shao Steel Group Corporation, a comprehensive steel

Zen Master Yuan Shao and His Mission to Cochinchina in the Seventeenth Century

When learning about the history of Buddhism in Vietnam,it is impossible not to mention the veteran bonzes of Linji School and Caodong School who traveled to Cochinchina to propagate Buddhism in the 17th century by sea.Zen Master Yuan Shao,known as one of the pioneers of Linji Chan School,laid the foundation for the formation and development of this school which still exists today.Based on previous studies from the perspective of Buddhist cultural exchanges between Cochinchina and China at that time,this article focuses on analyzing the social context,biography and preaching of Yuan Shao,a well-known zen master,in this area in order to present the significance of his contributions to Cochinchina Buddhism.The research methodology of the article is mainly based on the analysis and comparison of historical documents,records,related archeology.The above basic contents will be presented in an objective and systematic way as well as some raised scholarly debate is still ahead.

Love Makes Their Life Worth——Story about Shao Junke's help for the handicapped

The handicapped, a special group in society, usually encounter many difficulties in employment, marriage, and daily life.Some difficulties are what they cannot conquer by themselves. It is also not easy for them to integrate into society. However, if there is a person who helps the hand- icapped find a job, build up confidence and make their life worth; if there is a person who helps them set up their families and incorporate in a harmonious community;

Work Hard to Ensure Food,Drugs Safety for the People——An interview with Shao Mingli,director-general of the State Food and Drug Administration(SFDA)

Following is an interview given by Shao Mingli, director-general of China＇s State Food and Drug Administration to our reporter on what is being done to ensure food and drug safety in China. As everybody knows, food and drug safety is vital to people＇s lives.

Clinical application and research of Shao's “three-acupoint and five-needling method”

Professor SHAO Jing-ming has obtained more significant effect during the clinical practice in treatment of wheezing diseases by adopting ＂three-acupoint and five-needling method＂ created by himself, and the effect has been widely recognized by doctors and patients. After decades of development, Shao＇s ＂three-acupoint and five-needling method＂ has become a therapy with complete theoretical system and a large number of clinical research achievements, and its application scope has been expanded. In this paper, the achievements of Shao＇s ＂three-acupoint and five-needling method＂ during clinical studies in the early, middle and current development stages and related problems were reviewed comprehensively.

韶文化融入高校思想政治教育的现实意义和实现路径

韶文化作为中华优秀传统文化,具有“源、流、交、融”的内涵,包括红色文化、韶乐文化、家风文化、名人文化、工矿文化等文化内容,其精神特质为包容和谐、耕读传家、尽善尽美。韶文化融入高校思想政治教育对于韶文化、高校思想政治教育、大学生的发展均有现实意义,可以通过建设韶文化校园网站、挖掘韶文化教学资源、拓宽韶文化教学阵地,同时利用现代科技丰富教学,高校、政府、媒体合力育人的具体路径来实现韶文化融入高校思想政治教育。

邵达成的师范教育思想及当代价值

邵达成是湖北师范教育发展史上重要的教育家,他为湖北高等师范教育事业做出过重要贡献。邵达成在创办华中师范学院黄石分院过程中,他博大精深的师范教育思想成为办学兴校的关键法宝。通过对邵达成师范教育思想的透视,再次领悟他对立足师范教育,聚焦综合素养,坚持教师主导,发挥教研优势等方面的独特见地。邵达成的师范教育思想对我国当前高等师范院校发展变革具有重要借鉴意义,主要体现在为高等师范院校在发挥专业特色、加强师资培养、树立素养导向、深化科教融合等方面提供新的审思视角。

北平文化学社略考

北平文化学社是民国时期北京地区重要出版社之一,其成立与发展与北京师范大学有着相当的关联。本文通过对学社出版物和北京师范大学保存的相关史料进行梳理,对文化学社的历史做出初步考证。

邵达成高等教育管理思想及其当代价值

邵达成是中国著名的教育家,其高等教育管理思想的形成,是特殊的学习经历和马克思主义理论作用的产物,是长期高校管理实践的升华。邵达成的高等教育管理思想内涵丰富,体系完整,广泛涉及高等师范学院办学的政治立场、办学定位、培养目标、质量管理、教师管理等方面。从邵达成高等教育管理思想中汲取智慧和力量,高等师范院校要坚持立德树人,加强思想引领,回归教育本真;要找准办学定位,擦亮师范底色,坚守“师范为本”;要掌握方法,推进管理水平,提高育人质量;要提质教师队伍,优化师资保障,强化“以师为本”。

“少/免不得”“少/免/短不了”的情态演变及表达功用

能性述补词语“少/免不得”“少/免/短不了”经历了由道义情态到认识情态的演变过程。受“少”“免”“短”语义制约,以及“X不得”“X不了”结构的影响,五个词语在情态表达类别及使用频率上产生了此消彼长的变化。“少/免不得”出现早于“少/免不了”,前者数量由多到少,后者数量由少到多。“短不了”数量一直极低。“少不得”“少不了”多表道义情态,“免不得”“免不了”“短不了”多表认识情态。“少不得”“少不了”多后接中性成分,“免不得”“免不了”“短不了”多后接消极性成分。五者均都用于叙事,不同的是“少不得”还用于议论,“免不得”“免不了”多用于议论,“短不了”多用于对话。

得体乎?未得乎?——宋明理学对邵雍“老子得易之体”一语的讨论与争辩

伴随着理学的兴起与发展,尊儒教、辟异端(主要指释老之学)成为理学家的重要任务.对于老子其人其学,北宋邵雍有一句评语曰“老子知易之体”,此语后被朱熹转述为“老子得易之体”.邵雍的体用论自成一系,与程朱所秉持的“体用一源”的体用论并不相同.“老子知易之体”表达的是老子得易之虚体而未得易之神用.在未深究邵雍体用论的前提下,后世儒者将该语带入“体用一源”的框架内进行理解,将邵雍之意理解为扬老抑儒.朱熹、胡居仁、湛若水、纪大奎等人对此语严加攻驳,而王畿、田艺蘅等人则各辟蹊径,对邵雍之说加以肯定.老子究竟得“易之体”与否?其人其学究竟是体用兼该还是有体无用?这些问题在理学家群体中所引发的持久争辩,反映的是学者对易学主旨、儒道优劣、皇王正道与权谋智术之关系等问题的不同理解.