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Shift-share Analysis on International Tourism Competitiveness——A Case of Jiangsu Province 被引量:9
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作者 SHI Chunyun ZHANG Jie +1 位作者 YANG Yang ZHOU Zhang 《Chinese Geographical Science》 SCIE CSCD 2007年第2期173-178,共6页
Shift-share analysis has been confirmed a useful approach in the study of regional economics and many kinds of extended shift-share models have been advanced and put into practice in economic studies, but few have hit... Shift-share analysis has been confirmed a useful approach in the study of regional economics and many kinds of extended shift-share models have been advanced and put into practice in economic studies, but few have hitherto been introduced and applied to the tourism research in China. Moreover understanding the spatially competitive relationship is of paramount importance for marketers, developers, and planners involved in tourism strategy development. Based on international tourism receipts from 1995 to 2004, this study aims at probing into the spatial competitiveness of interna- tional tourism in Jiangsu Province in comparison with its neighbors by applying a spatially extended shift-share model and a modified dynamic shift-share model. The empirical results illustrate that exceptional years may exist in the ap- plication of dynamic shift-share models. To solve this issue, modifications to dynamic shift-share model are put forward. The analytical results are not only presented but also explained by the comparison of background conditions of tourism development between Jiangsu and its key competitors. The conclusions can be drawn that the growth of international tourism receipts in Jiangsu mainly attributes to the national component and the competitive component and Zhejiang is the most important rival to Jiangsu during the period of 1995-2004. In order to upgrade the tourism competitiveness, it is indispensable for Jiangsu to take proper positioning, promoting and marketing strategies and to cooperate and integrate with its main rivals. 展开更多
关键词 international tourism competitiveness spatially extended shift-share analysis model comparative static shift-share analysis modified dynamic shift-share analysis Jiangsu Province
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Industrial Structure and Competitive Strength of 31 Provincial Districts——A GIS-based Dynamic Shift-Share Analysis 被引量:2
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作者 GUO Wen-bo WAN Qing 《Asian Agricultural Research》 2011年第1期127-129,共3页
By using the dynamic shift-share analysis, the industrial structure and competitive strength of 31 provincial districts except Taiwan, Hong Kong and Macao are studied by taking the GDP of the three industries as the r... By using the dynamic shift-share analysis, the industrial structure and competitive strength of 31 provincial districts except Taiwan, Hong Kong and Macao are studied by taking the GDP of the three industries as the research entrance and the whole nation as the reference district. The industrial structure and competitive strength of each provincial district is measured. Through the analysis of pertinence, the correlation degree of industrial structure and industrial competitive strength to economic growth is analyzed. The results show that the industrial competitive strength is closely related to the economic growth of the 31 provincial districts, but the contribution made by the industrial structure to economic growth is insufficient and the effect of industrial structure does not match with that of industrial competitive strength. According to industrial competitiveness and industrial structure effect, 31 provincial districts of the whole nation are divided into 4 types and the relevant countermeasures of the four types are put forward. 展开更多
关键词 Dynamic shift-share analysis Industrial structure Competitive strength STRATEGY China
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A comparative study of manufacturing industrial competitiveness in eastern coastal provinces and cities of China based on shift-share analysis model
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作者 Yuan Aizhi 《Ecological Economy》 2009年第4期391-400,共10页
Manufacturing industry is an important symbol which weighs a local economy comprehensive strength and modernized level, and a mighty manufacturing industry is a reliable guarantee which realizes the industry moderniza... Manufacturing industry is an important symbol which weighs a local economy comprehensive strength and modernized level, and a mighty manufacturing industry is a reliable guarantee which realizes the industry modernization. The manufacturing industry in eastern coastal provinces and cities of China, including Shandong, Jiangsu, Zhejiang, Shanghai and Guangdong, holds a quite high proportion, and is competitive. But as to the interior, the manufacturing industry competitiveness of five provinces and cities actually has obviously gradient difference. The concrete profession&amp;#39;s competitiveness also has the characteristic respectively. This paper analyzes the competitiveness of manufacturing industry in five provinces and cities by the shift-share analysis, obtains a conclusion that Shandong and Zhejiang have the competitive advantage in the traditional manufacturing industry, that Jiangsu&amp;#39;s and Guangdong&amp;#39;s competitiveness lies in capital, technology-intensive industry, but that Shanghai manufacturing industry&amp;#39;s competitive advantage is not obvious, and then proposes strategy to promote the manufacturing industry in the eastern coastal provinces and cities. 展开更多
关键词 Manufacturing industry COMPETITIVENESS shift-share analysis
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The Fishery Industrial Structure in China Based on the Application of Shift-Share Analysis
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作者 Chao LU 《Asian Agricultural Research》 2016年第7期8-13,20,共7页
Taking sixteen main fishery production regions as the study objects,this paper is to examine the fishery industrial structure and investigate the correlation between the economic growth of the fishery industry and the... Taking sixteen main fishery production regions as the study objects,this paper is to examine the fishery industrial structure and investigate the correlation between the economic growth of the fishery industry and the fishery industrial structure during the period 1997-2013 by the shift-share analysis. The study results show that( i) four types of regional industrial structure exist in the fishery industry in China;( ii)all the three sectors-fishing production,fish processing( manufacturing) and fish marketing( distribution),have emerged with large potential for promoting the national fishery industry growth,especially for the latter two;( iii) the factors of industry-mix and competitive position have significantly different impacts on the growth of fishery industry in different main fishery production regions. This study is one of the comprehensive studies on the status of regional fishery industrial structure,and the competitiveness of regional fishery industry in China. 展开更多
关键词 FISHERY shift-share analysis Industry-mix SHARE COMPETITIVE position SHARE Impact
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Study on the Layout of China's National Strength in Strategic Science and Technology Based on the Shift-Share Analysis of Manufacturing Sector
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作者 WU Fuxiang WANG Zeyun 《Frontiers of Business Research in China》 2023年第3期327-353,共27页
The national strength in strategic science and technology is one of the key terms elaborated in the Report to the 20th National Congress of the Communist Party of China(CPC),highlighting its strategic significance for... The national strength in strategic science and technology is one of the key terms elaborated in the Report to the 20th National Congress of the Communist Party of China(CPC),highlighting its strategic significance for the manufacturing sector in enhancing China'sinternational competitiveness and overall innovation performance.Based on the shift-share analysis,significant regional disparities are noted in the distribution of national strength in strategic science and technology in the manufacturing sector in China.The northeast China region and the Yellow River middle reaches comprehensive economic region exhibit the highest industry mix effect in talent structure and in R&D structure.Furthermore,the computer and office equipment manufacturing industry shows a large spatial shift,indicating that the industry mix and spatial distribution of high-tech industries in China need urgent optimization.A comparison of international experiences in the building of national strength in strategic science and technology reveals that China faces problems such as imbalance of investment contributors,insufficient innovation synergy,and weak R&D domains.Therefore,it is necessary to apply a systemic approach to planning comprehensively for advancing the national strength in strategic science and technology.To this end,the immediate task is to mobilize national strategic scientific and technological capabilities to create a collaborative innovation complex. 展开更多
关键词 The Report to the 2Oth National Congress of the Communist Party of China national strengthhinstrategic science andtechnology shift-share analysis collaborative innovation complex
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Dynamic Interaction Analysis of Coupled Axial-Torsional-Lateral Mechanical Vibrations in Rotary Drilling Systems
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作者 Sabrina Meddah Sid Ahmed Tadjer +3 位作者 Abdelhakim Idir Kong Fah Tee Mohamed Zinelabidine Doghmane Madjid Kidouche 《Structural Durability & Health Monitoring》 EI 2025年第1期77-103,共27页
Maintaining the integrity and longevity of structures is essential in many industries,such as aerospace,nuclear,and petroleum.To achieve the cost-effectiveness of large-scale systems in petroleum drilling,a strong emp... Maintaining the integrity and longevity of structures is essential in many industries,such as aerospace,nuclear,and petroleum.To achieve the cost-effectiveness of large-scale systems in petroleum drilling,a strong emphasis on structural durability and monitoring is required.This study focuses on the mechanical vibrations that occur in rotary drilling systems,which have a substantial impact on the structural integrity of drilling equipment.The study specifically investigates axial,torsional,and lateral vibrations,which might lead to negative consequences such as bit-bounce,chaotic whirling,and high-frequency stick-slip.These events not only hinder the efficiency of drilling but also lead to exhaustion and harm to the system’s components since they are difficult to be detected and controlled in real time.The study investigates the dynamic interactions of these vibrations,specifically in their high-frequency modes,usingfield data obtained from measurement while drilling.Thefindings have demonstrated the effect of strong coupling between the high-frequency modes of these vibrations on drilling sys-tem performance.The obtained results highlight the importance of considering the interconnected impacts of these vibrations when designing and implementing robust control systems.Therefore,integrating these compo-nents can increase the durability of drill bits and drill strings,as well as improve the ability to monitor and detect damage.Moreover,by exploiting thesefindings,the assessment of structural resilience in rotary drilling systems can be enhanced.Furthermore,the study demonstrates the capacity of structural health monitoring to improve the quality,dependability,and efficiency of rotary drilling systems in the petroleum industry. 展开更多
关键词 Rotary drilling systems mechanical vibrations structural durability dynamic interaction analysis field data analysis
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Research status and prospects of the fractal analysis of metal material surfaces and interfaces
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作者 Qinjin Dai Xuefeng Liu +2 位作者 Xin Ma Shaojie Tian Qinghe Cui 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS 2025年第1期20-38,共19页
As a mathematical analysis method,fractal analysis can be used to quantitatively describe irregular shapes with self-similar or self-affine properties.Fractal analysis has been used to characterize the shapes of metal... As a mathematical analysis method,fractal analysis can be used to quantitatively describe irregular shapes with self-similar or self-affine properties.Fractal analysis has been used to characterize the shapes of metal materials at various scales and dimensions.Conventional methods make it difficult to quantitatively describe the relationship between the regular characteristics and properties of metal material surfaces and interfaces.However,fractal analysis can be used to quantitatively describe the shape characteristics of metal materials and to establish the quantitative relationships between the shape characteristics and various properties of metal materials.From the perspective of two-dimensional planes and three-dimensional curved surfaces,this paper reviews the current research status of the fractal analysis of metal precipitate interfaces,metal grain boundary interfaces,metal-deposited film surfaces,metal fracture surfaces,metal machined surfaces,and metal wear surfaces.The relationship between the fractal dimensions and properties of metal material surfaces and interfaces is summarized.Starting from three perspectives of fractal analysis,namely,research scope,image acquisition methods,and calculation methods,this paper identifies the direction of research on fractal analysis of metal material surfaces and interfaces that need to be developed.It is believed that revealing the deep influence mechanism between the fractal dimensions and properties of metal material surfaces and interfaces will be the key research direction of the fractal analysis of metal materials in the future. 展开更多
关键词 metal material surfaces and interfaces fractal analysis fractal dimension HOMOGENEITY
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Antioxidant and lipoxygenase inhibitory properties of a novel flavonoid from Pistacia chinensis Bunge and its molecular docking analysis
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作者 Abdur Rauf Zuneera Akram +6 位作者 Naveed Muhammad Najla AlMasoud Taghrid Saad Alomar Saima Naz Abdul Wadood Chandni Hayat Marcello Iriti 《Traditional Medicine Research》 2025年第2期30-36,共7页
Background:Pistacia chinensis Bunge has been traditionally used to manage various conditions,including asthma,pain,inflammation,hepatoprotection,and diabetes.The study was conducted to investigate the antioxidant and ... Background:Pistacia chinensis Bunge has been traditionally used to manage various conditions,including asthma,pain,inflammation,hepatoprotection,and diabetes.The study was conducted to investigate the antioxidant and anti-lipoxygenase(LOX)properties of the isolated compound 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one from Pistacia chinensis.Methods:LOX assay and antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl(DPPH)assay were performed.Molecular docking studies were conducted using a molecular operating environment.Results:The LOX assay revealed significant inhibitory effects at 0.2µM concentration,with an IC50 value of 37.80µM.The antioxidant effect demonstrated dose-dependency across 5 to 100µg/mL concentrations,reaching 93.09%at 100µg/mL,comparable to ascorbic acid’s 95.43%effect.Molecular docking studies highlighted strong interactions with the lipoxygenase enzyme,presenting an excellent docking score of-10.98 kcal/mol.Conclusion:These findings provide valuable insights into Pistacia chinensis’chemical components and biological effects,reinforcing its traditional medicinal applications. 展开更多
关键词 Pistacia chinensis Bunge ANTIOXIDANT DPPH assay antilipoxygenase docking analysis
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Prenatal ultrasonography and genetic analysis of fetal cleidocranial dysplasia:A case report
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作者 Feng Wang Pei-Feng Dai Wen-Juan Gao 《World Journal of Clinical Cases》 SCIE 2025年第10期28-34,共7页
BACKGROUND Cleidocranial dysplasia(CCD)is an infrequent clinical condition with an autosomal dominant inheritance pattern.It is characterized by abnormal clavicles,patent sutures and fontanelles,supernumerary teeth,an... BACKGROUND Cleidocranial dysplasia(CCD)is an infrequent clinical condition with an autosomal dominant inheritance pattern.It is characterized by abnormal clavicles,patent sutures and fontanelles,supernumerary teeth,and short stature.Approximately 60%-70%of patients with CCD have mutations in the RUNX family transcription factor 2 gene.However,prenatal diagnosis of CCD is difficult when the family history is unknown.CASE SUMMARY We report a rare case of fetal CCD with an unknown family history,confirmed by prenatal ultrasonography and genetic testing at a gestational age of 16 weeks.The genetic reports indicated that the fetus carried pathogenic mutations in the RUNX family transcription factor 2 gene(c.674G>A).After careful consideration,the pregnant woman and her family decided to continue the pregnancy.CONCLUSION Definitive prenatal diagnosis of CCD should include family history,ultrasound diagnosis,and genetic analysis,especially if family history is unknown. 展开更多
关键词 Cleidocranial dysplasia Genetic analysis Ultrasonic diagnosis PRENATAL Case report
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Retrospective analysis of pathological types and imaging features in pancreatic cancer: A comprehensive study
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作者 Yang-Gang Luo Mei Wu Hong-Guang Chen 《World Journal of Gastrointestinal Oncology》 SCIE 2025年第1期121-129,共9页
BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features ... BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late diagnosis.Understanding the correlation between pathological type and imaging features is crucial for early detection and appropriate treatment planning.AIM To retrospectively analyze the relationship between different pathological types of pancreatic cancer and their corresponding imaging features.METHODS We retrospectively analyzed the data of 500 patients diagnosed with pancreatic cancer between January 2010 and December 2020 at our institution.Pathological types were determined by histopathological examination of the surgical spe-cimens or biopsy samples.The imaging features were assessed using computed tomography,magnetic resonance imaging,and endoscopic ultrasound.Statistical analyses were performed to identify significant associations between pathological types and specific imaging characteristics.RESULTS There were 320(64%)cases of pancreatic ductal adenocarcinoma,75(15%)of intraductal papillary mucinous neoplasms,50(10%)of neuroendocrine tumors,and 55(11%)of other rare types.Distinct imaging features were identified in each pathological type.Pancreatic ductal adenocarcinoma typically presents as a hypodense mass with poorly defined borders on computed tomography,whereas intraductal papillary mucinous neoplasms present as characteristic cystic lesions with mural nodules.Neuroendocrine tumors often appear as hypervascular lesions in contrast-enhanced imaging.Statistical analysis revealed significant correlations between specific imaging features and pathological types(P<0.001).CONCLUSION This study demonstrated a strong association between the pathological types of pancreatic cancer and imaging features.These findings can enhance the accuracy of noninvasive diagnosis and guide personalized treatment approaches. 展开更多
关键词 Pancreatic cancer Pathological types Imaging features Retrospective analysis Diagnostic accuracy
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Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions
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作者 Bo-Fan Chen Li Liu +13 位作者 Fang-Zhen Lin Hai-Min Zeng Hai-Qiang Huang Chun-Fang Zhang Cong-Cong Liu Xiang Chen Jie Peng Yun-Fa Wang Zhi-Lin Wang Bin Chen De-Le Liu Yun Liu Zheng-Zheng Li Xin-Xing Zeng 《World Journal of Psychiatry》 SCIE 2025年第1期153-167,共15页
BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood swings.Effective drug treatment modalities are crucial for managing BD.AIM To analyze the current status and future trends of... BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood swings.Effective drug treatment modalities are crucial for managing BD.AIM To analyze the current status and future trends of global research on BD drug treatment over the last decade.METHODS The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were extracted.Data visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration networks.The University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this field.The Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited paper.CONCLUSION This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future directions.The study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy. 展开更多
关键词 Bipolar disorder Drug treatment Bibliometric analysis VISUALIZATION Mental disorder
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Targeted gene sequencing and bioinformatics analysis of patients with gallbladder neuroendocrine carcinoma:A case report
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作者 Yun-Chuan Yang Zhi-Tao Chen +2 位作者 Da-Long Wan Hui Tang Mu-Lin Liu 《World Journal of Gastrointestinal Oncology》 SCIE 2025年第1期239-251,共13页
BACKGROUND Gallbladder neuroendocrine carcinoma(NEC)represents a subtype of gallbladder malignancies characterized by a low incidence,aggressive nature,and poor prognosis.Despite its clinical severity,the genetic alte... BACKGROUND Gallbladder neuroendocrine carcinoma(NEC)represents a subtype of gallbladder malignancies characterized by a low incidence,aggressive nature,and poor prognosis.Despite its clinical severity,the genetic alterations,mechanisms,and signaling pathways underlying gallbladder NEC remain unclear.CASE SUMMARY This case study presents a rare instance of primary gallbladder NEC in a 73-year-old female patient,who underwent a radical cholecystectomy with hepatic hilar lymphadenectomy and resection of liver segments IV-B and V.Targeted gene sequencing and bioinformatics analysis tools,including STRING,GeneMANIA,Metascape,TRRUST,Sangerbox,cBioPortal and GSCA,were used to analyze the biological functions and features of mutated genes in gallbladder NEC.Twelve mutations(APC,ARID2,IFNA6,KEAP1,RB1,SMAD4,TP53,BTK,GATA1,GNAS,and PRDM3)were identified,and the tumor mutation burden was determined to be 9.52 muts/Mb via targeted gene sequencing.A protein-protein interaction network showed significant interactions among the twelve mutated genes.Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were used to assess mutation functions and pathways.The results revealed 40 tumor-related pathways.A key regulatory factor for gallbladder NEC-related genes was identified,and its biological functions and features were compared with those of gallbladder carcinoma.CONCLUSION Gallbladder NEC requires standardized treatment.Comparisons with other gallbladder carcinomas revealed clinical phenotypes,molecular alterations,functional characteristics,and enriched pathways. 展开更多
关键词 Gallbladder neuroendocrine carcinoma Targeted-gene sequencing Bioinformatics analysis case report IMMUNOCYTOCHEMISTRY Case report
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Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury
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作者 Xizi Song Ruixin Li +6 位作者 Xiaolei Chu Qi Li Ruihua Li Qingwen Li Kai-Yu Tong Xiaosong Gu Dong Ming 《Neural Regeneration Research》 SCIE CAS 2025年第10期2807-2822,共16页
Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and disabilities.Research on the pathogenesis of peripheral nerve injury has focused on pathological changes... Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and disabilities.Research on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target organs.This has led to restrictions on current therapeutic approaches.In this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target organs.After peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal cord.The nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury site.Corresponding damage to target organs can occur,including skeletal muscle atrophy and sensory receptor disruption.We then provide a brief review of the research advances in therapeutic approaches to peripheral nerve injury.The main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical exercise.However,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ pathway.Therefore,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery. 展开更多
关键词 central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach
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Industrial Structure Evolution and Economic Growth in Dingxi City Based on Shift-Share Method and Location Quotient Analysis
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作者 XU Bao-jin1, CHEN Xing-peng1, WANG Li-na2 1.College of Resources and Environmental Sciences, Lanzhou University, Lanzhou 730000, China 2, Xi’an Changqing Techonoloyg Engineering Co., Ltd., Changqing Oilfield Company, Xian 710018, China 《Asian Agricultural Research》 2010年第12期61-64,共4页
According to the statistical data in the years 2004-2008, both Shift-Share Analysis and Location Quotient Analysis are used to compare the economic development status of counties (districts) in Dingxi City in the year... According to the statistical data in the years 2004-2008, both Shift-Share Analysis and Location Quotient Analysis are used to compare the economic development status of counties (districts) in Dingxi City in the years 2004 and 2008. Advantages and disadvantages of industrial structure and competitiveness are analyzed, as well as the impacts of existing industrial structure on economic growth. Development direction and development focus of primary, secondary and tertiary industries are found out. Countermeasures for accelerating the economic development of counties (districts) in Dingxi City are put forward, such as increasing the inputs in characteristic agriculture, promoting the development of primary industry, speeding up the construction of large and medium industrial enterprises, enhancing the development of secondary industry, strengthening comprehensive environmental improvement in tourist area, and actively developing tertiary industry. 展开更多
关键词 shift-share analysis LOCATION QUOTIENT INDUSTRIAL
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长三角城市群经济韧性测度与分析——基于Shift-Share的经济韧性分解
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作者 王欢芳 陈素月 《兰州财经大学学报》 2024年第2期48-61,共14页
以长三角城市群27个城市为研究对象,测度2008—2010年抵抗期和2010—2019年恢复期城市群经济韧性水平,并进一步运用Shift-Share分解方法探索长三角城市群经济韧性内在影响机制。研究显示:抵抗期和恢复期中长三角城市群经济韧性均值分别... 以长三角城市群27个城市为研究对象,测度2008—2010年抵抗期和2010—2019年恢复期城市群经济韧性水平,并进一步运用Shift-Share分解方法探索长三角城市群经济韧性内在影响机制。研究显示:抵抗期和恢复期中长三角城市群经济韧性均值分别为0.309和0.301,均强于全国层面经济韧性水平;Shift-Share分解后发现竞争力分量对各城市经济韧性水平提升起到决定性作用,抵抗期阶段主要由第二、三产业共同作用影响经济韧性水平;恢复期阶段则以第二产业竞争力为主导力量,同时以第三产业竞争力作为辅助力量。通过实证探究长三角城市群经济一体化发展的规律和特点,为增强中国经济韧性提出相关建议,助力中国经济高质量发展。 展开更多
关键词 长三角城市群 经济韧性 shift-share分解 产业结构 竞争力
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Screening biomarkers for spinal cord injury using weighted gene co-expression network analysis and machine learning 被引量:5
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作者 Xiaolu Li Ye Yang +3 位作者 Senming Xu Yuchang Gui Jianmin Chen Jianwen Xu 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第12期2723-2734,共12页
Immune changes and inflammatory responses have been identified as central events in the pathological process of spinal co rd injury.They can greatly affect nerve regeneration and functional recovery.However,there is s... Immune changes and inflammatory responses have been identified as central events in the pathological process of spinal co rd injury.They can greatly affect nerve regeneration and functional recovery.However,there is still limited understanding of the peripheral immune inflammato ry response in spinal cord inju ry.In this study.we obtained microRNA expression profiles from the peripheral blood of patients with spinal co rd injury using high-throughput sequencing.We also obtained the mRNA expression profile of spinal cord injury patients from the Gene Expression Omnibus(GEO)database(GSE151371).We identified 54 differentially expressed microRNAs and 1656 diffe rentially expressed genes using bioinformatics approaches.Functional enrichment analysis revealed that various common immune and inflammation-related signaling pathways,such as neutrophil extracellular trap formation pathway,T cell receptor signaling pathway,and nuclear factor-κB signal pathway,we re abnormally activated or inhibited in spinal cord inju ry patient samples.We applied an integrated strategy that combines weighted gene co-expression network analysis,LASSO logistic regression,and SVM-RFE algorithm and identified three biomarke rs associated with spinal cord injury:ANO10,BST1,and ZFP36L2.We verified the expression levels and diagnostic perfo rmance of these three genes in the original training dataset and clinical samples through the receiver operating characteristic curve.Quantitative polymerase chain reaction results showed that ANO20 and BST1 mRNA levels were increased and ZFP36L2 mRNA was decreased in the peripheral blood of spinal cord injury patients.We also constructed a small RNA-mRNA interaction network using Cytoscape.Additionally,we evaluated the proportion of 22 types of immune cells in the peripheral blood of spinal co rd injury patients using the CIBERSORT tool.The proportions of naive B cells,plasma cells,monocytes,and neutrophils were increased while the proportions of memory B cells,CD8^(+)T cells,resting natural killer cells,resting dendritic cells,and eosinophils were markedly decreased in spinal cord injury patients increased compared with healthy subjects,and ANO10,BST1 and ZFP26L2we re closely related to the proportion of certain immune cell types.The findings from this study provide new directions for the development of treatment strategies related to immune inflammation in spinal co rd inju ry and suggest that ANO10,BST2,and ZFP36L2 are potential biomarkers for spinal cord injury.The study was registe red in the Chinese Clinical Trial Registry(registration No.ChiCTR2200066985,December 12,2022). 展开更多
关键词 bioinformatics analysis BIOMARKER CIBERSORT GEO dataset LASSO miRNA-mRNA network RNA sequencing spinal cord injury SVM-RFE weighted gene co-expression network analysis
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Social-ecological perspective on the suicidal behaviour factors of early adolescents in China:a network analysis 被引量:4
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作者 Yuan Li Peiying Li +5 位作者 Mengyuan Yuan Yonghan Li Xueying Zhang Juan Chen Gengfu Wang Puyu Su 《General Psychiatry》 CSCD 2024年第1期143-150,共8页
Background In early adolescence,youth are highly prone to suicidal behaviours.Identifying modifiable risk factors during this critical phase is a priority to inform effective suicide prevention strategies.Aims To expl... Background In early adolescence,youth are highly prone to suicidal behaviours.Identifying modifiable risk factors during this critical phase is a priority to inform effective suicide prevention strategies.Aims To explore the risk and protective factors of suicidal behaviours(ie,suicidal ideation,plans and attempts)in early adolescence in China using a social-ecological perspective.Methods Using data from the cross-sectional project‘Healthy and Risky Behaviours Among Middle School Students in Anhui Province,China',stratified random cluster sampling was used to select 5724 middle school students who had completed self-report questionnaires in November 2020.Network analysis was employed to examine the correlates of suicidal ideation,plans and attempts at four levels,namely individual(sex,academic performance,serious physical llness/disability,history of self-harm,depression,impulsivity,sleep problems,resilience),family(family economic status,relationship with mother,relationship with father,family violence,childhood abuse,parental mental illness),school(relationship with teachers,relationship with classmates,school-bullying victimisation and perpetration)and social(social support,satisfaction with society).Results In total,37.9%,19.0%and 5.5%of the students reported suicidal ideation,plans and attempts in the past 6 months,respectively.The estimated network revealed that suicidal ideation,plans and attempts were collectively associated with a history of self-harm,sleep problems,childhood abuse,school bullying and victimisation.Centrality analysis indicated that the most influential nodes in the network were history of self-harm and childhood abuse.Notably,the network also showed unique correlates of suicidal ideation(sex,weight=0.60;impulsivity,weight=0.24;family violence,weight=0.17;relationship with teachers,weight=-0.03;school-bullying perpetration,weight=0.22),suicidal plans(social support,weight=-0.15)and suicidal attempts(relationship with mother,weight=-0.10;parental mental llness,weight=0.61).Conclusions This study identified the correlates of suicidal ideation,plans and attempts,and provided practical implications for suicide prevention for young adolescents in China.Firstly,this study highlighted the importance of joint interventions across multiple departments.Secondly,the common risk factors of suicidal ideation,plans and attempts were elucidated.Thirdly,this study proposed target interventions to address the unique influencing factors of suicidal ideation,plans and attempts. 展开更多
关键词 NETWORK analysis PREVENTION
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基于改进Theil指数和Shift-Share模型的2012—2021年中国产业偏离分析
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作者 高孝伟 张颖昆 +1 位作者 李华 王苏梦 《资源与产业》 2024年第1期15-24,共10页
文章首先通过对现有文献的梳理和分析,发现针对产业偏离的测算,传统的产业偏离度E系数、Theil指数及Shift-Share模型均存在一定的缺陷,E系数和Theil指数的缺陷主要体现在计算原理方面,而Shift-Share模型的缺陷主要表现在参照系选择的合... 文章首先通过对现有文献的梳理和分析,发现针对产业偏离的测算,传统的产业偏离度E系数、Theil指数及Shift-Share模型均存在一定的缺陷,E系数和Theil指数的缺陷主要体现在计算原理方面,而Shift-Share模型的缺陷主要表现在参照系选择的合理性和数据采集的可行性方面。然后,基于现有模型的基本原理,提出了更为合理和更具可操作性的产业偏离测算方法,再采用实证研究的方法,根据2012—2021年的数据,对中国的产业偏离情况进行具体分析,得出尽管中国存在产业偏离,但产业偏离度在逐渐减小。最后,基于修正模型的计算结果,并结合当前的国际国内环境,提出如下政策建议:1)第一产业要依靠创新和科技引领,促进农村劳动力在城乡间有序转移,实现农业生产的规模化和现代化;2)第二产业要加快产业的升级换代,建立和保持独立、自主、完整的工业体系,加大在基础研究方面的投入,尽早突破美西方的技术封锁;3)第三产业的发展重点应该在金融和科教两个方面,要进一步提升香港地区、上海和北京等城市的世界金融中心地位,依靠金融创新来规避现行国际金融体系的不利约束和影响,同时要将科教兴国战略落到实处,努力探索适合中国国情的从小学到大学各阶段的教育模式。 展开更多
关键词 三次产业 偏离度 THEIL系数 shift-share模型 产业结构优化
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Advances in microfluidic-based DNA methylation analysis 被引量:1
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作者 Jiwen Li Tiechuan Li Xuexin Duan 《Nanotechnology and Precision Engineering》 EI CAS CSCD 2024年第1期116-134,共19页
DNA methylation has been extensively investigated in recent years,not least because of its known relationship with various diseases.Progress in analytical methods can greatly increase the relevance of DNA methylation ... DNA methylation has been extensively investigated in recent years,not least because of its known relationship with various diseases.Progress in analytical methods can greatly increase the relevance of DNA methylation studies to both clinical medicine and scientific research.Microflu-idic chips are excellent carriers for molecular analysis,and their use can provide improvements from multiple aspects.On-chip molecular analysis has received extensive attention owing to its advantages of portability,high throughput,low cost,and high efficiency.In recent years,the use of novel microfluidic chips for DNA methylation analysis has been widely reported and has shown obvious superiority to conventional methods.In this review,wefirst focus on DNA methylation and its applications.Then,we discuss advanced microfluidic-based methods for DNA methylation analysis and describe the great progress that has been made in recent years.Finally,we summarize the advantages that microfluidic technology brings to DNA methylation analysis and describe several challenges and perspectives for on-chip DNA methylation analysis.This review should help researchers improve their understanding and make progress in developing microfluidic-based methods for DNA methylation analysis. 展开更多
关键词 Microfluidic chip DNA methylation analysis Molecular analysis High throughput Low cost
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A Review on Sources,Extractions and Analysis Methods of a Sustainable Biomaterial:Tannins 被引量:2
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作者 Antonio Pizzi Marie-Pierre Laborie Zeki Candan 《Journal of Renewable Materials》 EI CAS 2024年第3期397-425,共29页
Condensed and hydrolysable tannins are non-toxic natural polyphenols that are a commercial commodity industrialized for tanning hides to obtain leather and for a growing number of other industrial applications mainly ... Condensed and hydrolysable tannins are non-toxic natural polyphenols that are a commercial commodity industrialized for tanning hides to obtain leather and for a growing number of other industrial applications mainly to substitute petroleum-based products.They are a definite class of sustainable materials of the forestry industry.They have been in operation for hundreds of years to manufacture leather and now for a growing number of applications in a variety of other industries,such as wood adhesives,metal coating,pharmaceutical/medical applications and several others.This review presents the main sources,either already or potentially commercial of this forestry by-materials,their industrial and laboratory extraction systems,their systems of analysis with their advantages and drawbacks,be these methods so simple to even appear primitive but nonetheless of proven effectiveness,or very modern and instrumental.It constitutes a basic but essential summary of what is necessary to know of these sustainable materials.In doing so,the review highlights some of the main challenges that remain to be addressed to deliver the quality and economics of tannin supply necessary to fulfill the industrial production requirements for some materials-based uses. 展开更多
关键词 TANNINS FLAVONOIDS SOURCES extraction methods analysis methods
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