Shorter product life cycles present new dressed in supply chain literature. This research challenges to managing production and logistics not adequately adaddresses issues pertaining to the management of supply chains...Shorter product life cycles present new dressed in supply chain literature. This research challenges to managing production and logistics not adequately adaddresses issues pertaining to the management of supply chains in a short life cycle environment. In this paper, we study the short life cycle environment; then we develop the ventory policy of the indirect manufacturer by explicitly using his demand us an output of the retailer's optimal inoptimal ordering policy. Finally, we also provide causes of the bullwhip effect in the context of short life cycle products.展开更多
Introduction: Cancer is a chronic debilitating disease that unnerves patients, communities, and nations. At some point in cancer patient’s disease experience, chemotherapy is used, and the patient is expected to adhe...Introduction: Cancer is a chronic debilitating disease that unnerves patients, communities, and nations. At some point in cancer patient’s disease experience, chemotherapy is used, and the patient is expected to adhere to treatment to improve survival and quality of life. Methods: This multisite Cluster Randomized Trial (CRT) evaluated the effectiveness of mobile phone Short Message Service (SMS) support on the adherence to treatment schedules among adult cancer patients in Kenya. Data was collected using questionnaires. Ethical approvals were obtained from relevant Ethical Review Boards (ERBs). Results: The mean adherence was 83%. There was a significant difference between treatment arms in relation to the adherence. The intervention arm had a higher mean adherence difference, M = 3.913, 95% CI 2.632-5.193, t (402) = 6.006, p ≤ 0.001), with Cohen’s d = 0.60. Although not significant, (χ<sup>2</sup>dd = 0.151, df = 1, p = 2.064), more women were perfect adheres than males. Perfect adherers were satisfied with SMS support (χ<sup>2</sup>dd = 7.620, df = 1, p = 0.06), were in the intervention arm (χ<sup>2</sup>dd = 22.942, df = 1, p ≤ 0.001), and had trust in the care provider (χ<sup>2</sup>dd = 10.591 p ≤ 0.001). SMS support was not significant in the multivariate analysis but had an estimated effect size of 0.958 (z = 1.424, p = 0.154, CI = 0.242-3.781), indicating that mean adherence was slightly better in the presence of the intervention. Conclusions: SMS-support intervention has demonstrated superiority in influencing adherence. Further, health system-related factors have a significant influence on the adherence to chemotherapy treatment. Interventions to re-design health systems that are responsive to unmet care needs of cancer patients must be explored. .展开更多
Traditional inventory models are mostly ignorant of the life cycle dynamics of a technology product;hence,they often fail to identify different dimensions of inventory research.This paper attempts to investigate the r...Traditional inventory models are mostly ignorant of the life cycle dynamics of a technology product;hence,they often fail to identify different dimensions of inventory research.This paper attempts to investigate the relationship between adoption behavior of customers using life cycle dynamics and associated trade credit policies in order to optimize the total inventory cost.The demand model used in this paper treats sales as a function of awareness diffusion and adoption.Awareness is considered as a function of feedback effects from users/customers.Retailer’s optimal strategies for short life cycle product under credit financing were determined analytically.Finally,numerical examples have been used to support the theoretical results.Theoretical results have further been used to gain some managerial insights.展开更多
Ernest Hemingway's world-wide influence and distinctive writing style-the Iceberg Style-caused a stylistic revolution in the field of literature all over the world.Hemingway always tries his best to avoid depictin...Ernest Hemingway's world-wide influence and distinctive writing style-the Iceberg Style-caused a stylistic revolution in the field of literature all over the world.Hemingway always tries his best to avoid depicting things by piling gorgeously big words;on the contrary,he adopts direct description and short sentences which are precise,laconic,bright and vivid.For instance,the novel titled The Short and Happy Life of Francis Macomber is universally acknowledged as his masterpiece,in which "Iceberg Theory"is skillfully presented.With a full analysis of the story,the uniqueness of "Iceberg Theory"will be emphasized in this paper.展开更多
"The Short Happy Life of Francis Macomber",is a representative short story of Hemingway since it clearly embodies hisprinciple of creation.To illustrate the unequal relationship between the hero Macomber and..."The Short Happy Life of Francis Macomber",is a representative short story of Hemingway since it clearly embodies hisprinciple of creation.To illustrate the unequal relationship between the hero Macomber and the heroine Margot,this paper employsBurton’s(1980)Discourse Framework theory to analyze the distribution,classification and pattern of these two characters’chal-lenging moves.On the basis of the dialogue analysis,the author attempts to analyze the patterns of their challenging moves,whichcan reflect Macomber is in a more inferior position in marriage than his wife.And the reasons for this are Margot not only holdsmany challenging moves but also seizes the speaking rights in communication.展开更多
Background: To understand what life is like for US children with a diagnosis of Growth Hormone Deficiency or Idiopathic Short Stature, the impact of short stature on Health related Quality of Life (HrQoL) was qualitat...Background: To understand what life is like for US children with a diagnosis of Growth Hormone Deficiency or Idiopathic Short Stature, the impact of short stature on Health related Quality of Life (HrQoL) was qualitatively examined and needs for care from the young patients and their parents perspective were identified. Methods: Focus group discussions with 26 American-English speaking and nine American-Spanish speaking children and their parents were conducted, transcribed verbatim and subsequently qualitatively analyzed by two independent raters, using an existing coding guideline, based on the multidimensional HrQoL concept and a special software (VERBI-Software MAXQDA 10). Results: A total of 1313 statements for the English-speaking and 447 statements for the Spanish-speaking families were categorized. In the US, the strongest frequency of mention was found for the HrQoL dimension “Social” across respondents, followed by “Treatment” and “Emotion”. Conclusion: Conducting and analyzing data generated from focus groups ensure that young patients’ experiences of disease are represented in the measure of outcomes for use in clinical trials and patient care.展开更多
The fatigue crack initiation from notch root and the short-crack growth laws of two medium carbon alloying structural steels—35CrMo and 42CrMo are investigated under the different stress ratios R =0.1, 0.3) and th...The fatigue crack initiation from notch root and the short-crack growth laws of two medium carbon alloying structural steels—35CrMo and 42CrMo are investigated under the different stress ratios R =0.1, 0.3) and three-point bending condition. The relationships between the maximum stress range at the notch root Δ σ max and the number of cycles before fatigue crack initiation N i are determined. The threshold stresses of fatigue crack initiation (Δ σ max ) th are got, and the smallcrack growth laws are obtained for these steels. An effective and convenient method is proposed for predicting the fatigue life of the notch specimens.展开更多
文摘Shorter product life cycles present new dressed in supply chain literature. This research challenges to managing production and logistics not adequately adaddresses issues pertaining to the management of supply chains in a short life cycle environment. In this paper, we study the short life cycle environment; then we develop the ventory policy of the indirect manufacturer by explicitly using his demand us an output of the retailer's optimal inoptimal ordering policy. Finally, we also provide causes of the bullwhip effect in the context of short life cycle products.
文摘Introduction: Cancer is a chronic debilitating disease that unnerves patients, communities, and nations. At some point in cancer patient’s disease experience, chemotherapy is used, and the patient is expected to adhere to treatment to improve survival and quality of life. Methods: This multisite Cluster Randomized Trial (CRT) evaluated the effectiveness of mobile phone Short Message Service (SMS) support on the adherence to treatment schedules among adult cancer patients in Kenya. Data was collected using questionnaires. Ethical approvals were obtained from relevant Ethical Review Boards (ERBs). Results: The mean adherence was 83%. There was a significant difference between treatment arms in relation to the adherence. The intervention arm had a higher mean adherence difference, M = 3.913, 95% CI 2.632-5.193, t (402) = 6.006, p ≤ 0.001), with Cohen’s d = 0.60. Although not significant, (χ<sup>2</sup>dd = 0.151, df = 1, p = 2.064), more women were perfect adheres than males. Perfect adherers were satisfied with SMS support (χ<sup>2</sup>dd = 7.620, df = 1, p = 0.06), were in the intervention arm (χ<sup>2</sup>dd = 22.942, df = 1, p ≤ 0.001), and had trust in the care provider (χ<sup>2</sup>dd = 10.591 p ≤ 0.001). SMS support was not significant in the multivariate analysis but had an estimated effect size of 0.958 (z = 1.424, p = 0.154, CI = 0.242-3.781), indicating that mean adherence was slightly better in the presence of the intervention. Conclusions: SMS-support intervention has demonstrated superiority in influencing adherence. Further, health system-related factors have a significant influence on the adherence to chemotherapy treatment. Interventions to re-design health systems that are responsive to unmet care needs of cancer patients must be explored. .
文摘Traditional inventory models are mostly ignorant of the life cycle dynamics of a technology product;hence,they often fail to identify different dimensions of inventory research.This paper attempts to investigate the relationship between adoption behavior of customers using life cycle dynamics and associated trade credit policies in order to optimize the total inventory cost.The demand model used in this paper treats sales as a function of awareness diffusion and adoption.Awareness is considered as a function of feedback effects from users/customers.Retailer’s optimal strategies for short life cycle product under credit financing were determined analytically.Finally,numerical examples have been used to support the theoretical results.Theoretical results have further been used to gain some managerial insights.
文摘Ernest Hemingway's world-wide influence and distinctive writing style-the Iceberg Style-caused a stylistic revolution in the field of literature all over the world.Hemingway always tries his best to avoid depicting things by piling gorgeously big words;on the contrary,he adopts direct description and short sentences which are precise,laconic,bright and vivid.For instance,the novel titled The Short and Happy Life of Francis Macomber is universally acknowledged as his masterpiece,in which "Iceberg Theory"is skillfully presented.With a full analysis of the story,the uniqueness of "Iceberg Theory"will be emphasized in this paper.
文摘"The Short Happy Life of Francis Macomber",is a representative short story of Hemingway since it clearly embodies hisprinciple of creation.To illustrate the unequal relationship between the hero Macomber and the heroine Margot,this paper employsBurton’s(1980)Discourse Framework theory to analyze the distribution,classification and pattern of these two characters’chal-lenging moves.On the basis of the dialogue analysis,the author attempts to analyze the patterns of their challenging moves,whichcan reflect Macomber is in a more inferior position in marriage than his wife.And the reasons for this are Margot not only holdsmany challenging moves but also seizes the speaking rights in communication.
文摘Background: To understand what life is like for US children with a diagnosis of Growth Hormone Deficiency or Idiopathic Short Stature, the impact of short stature on Health related Quality of Life (HrQoL) was qualitatively examined and needs for care from the young patients and their parents perspective were identified. Methods: Focus group discussions with 26 American-English speaking and nine American-Spanish speaking children and their parents were conducted, transcribed verbatim and subsequently qualitatively analyzed by two independent raters, using an existing coding guideline, based on the multidimensional HrQoL concept and a special software (VERBI-Software MAXQDA 10). Results: A total of 1313 statements for the English-speaking and 447 statements for the Spanish-speaking families were categorized. In the US, the strongest frequency of mention was found for the HrQoL dimension “Social” across respondents, followed by “Treatment” and “Emotion”. Conclusion: Conducting and analyzing data generated from focus groups ensure that young patients’ experiences of disease are represented in the measure of outcomes for use in clinical trials and patient care.
文摘The fatigue crack initiation from notch root and the short-crack growth laws of two medium carbon alloying structural steels—35CrMo and 42CrMo are investigated under the different stress ratios R =0.1, 0.3) and three-point bending condition. The relationships between the maximum stress range at the notch root Δ σ max and the number of cycles before fatigue crack initiation N i are determined. The threshold stresses of fatigue crack initiation (Δ σ max ) th are got, and the smallcrack growth laws are obtained for these steels. An effective and convenient method is proposed for predicting the fatigue life of the notch specimens.