Objective: To probe the possibility of functional sensory endings regeneration after end-to-side neurorrhaphy. Methods: Fifteen New Zealand rabbits were used in this study. The left greater auricular nerve served as t...Objective: To probe the possibility of functional sensory endings regeneration after end-to-side neurorrhaphy. Methods: Fifteen New Zealand rabbits were used in this study. The left greater auricular nerve served as the donor nerve. A nerve ed taken from the right ear served as the receptive nerve which anastomosed to the donor nerve by means of end-to-side method and the other end implanted into the denervated skin flap. Normal skin and denervated skin flap without nerve implantation served as control groups, 5 animals in each group. The single nerve fibre recording technique was used to investigate the number, distribution and types of regenerated discharging nerve fibers 4 mouths after operation. Results: The inductive discharges of nerve fibres wave observed in all types of regenerated sensory nerves, the total discharging fibers was about 58% of that in normal skin. Few discharging fibers were observed in denervated skin flap without nerve implantation. Conclusion: End-to-side neurorrhaphy can regenerate functional axons.展开更多
文摘Objective: To probe the possibility of functional sensory endings regeneration after end-to-side neurorrhaphy. Methods: Fifteen New Zealand rabbits were used in this study. The left greater auricular nerve served as the donor nerve. A nerve ed taken from the right ear served as the receptive nerve which anastomosed to the donor nerve by means of end-to-side method and the other end implanted into the denervated skin flap. Normal skin and denervated skin flap without nerve implantation served as control groups, 5 animals in each group. The single nerve fibre recording technique was used to investigate the number, distribution and types of regenerated discharging nerve fibers 4 mouths after operation. Results: The inductive discharges of nerve fibres wave observed in all types of regenerated sensory nerves, the total discharging fibers was about 58% of that in normal skin. Few discharging fibers were observed in denervated skin flap without nerve implantation. Conclusion: End-to-side neurorrhaphy can regenerate functional axons.
基金Supported by State Key Laboratory of Ocean Engineering (Shanghai Jiao Tong University)(Grant No.0804)the Fundamental Research Funds for the Central Universities (HEUCFZ1001)International Science and Technology Cooperation Project (2007DFR80340)
