Herein we report a high-gain signal-on poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(PEDOT:PSS)organic electrochemical transistor(OECT)biosensing using an accumulation-mode PEDOT:PSS OECT modulated by a lig...Herein we report a high-gain signal-on poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(PEDOT:PSS)organic electrochemical transistor(OECT)biosensing using an accumulation-mode PEDOT:PSS OECT modulated by a light-fueled MXene/MOFs/Ni O Schottky heterojunction.In such a system,the MXene/MOFs/Ni O Schottky heterojunction exhibited superior gating effect,as it not only enabled the fast-directional charge transfer but also guaranteed the maximal accessibility of the electrolyte to topped 2D MXene with large surface area.In linkage with a bi-enzyme cascade system,the quinone derivatives produced by the cascade reaction of alkaline phosphatase(ALP)and tyrosinase(TYR)could serve as effective electron acceptors for the representative Ti_(3)C_(2)/PCN-224/Ni O heterojunction,underpinning an innovative method for sensitive detection of ALP activity with a low detection limit of 0.001 U L^(-1).Remarkably,the as-developed system demonstrated a remarkable current gain as high as near 10^(4),which to our knowledge is the highest one among existing OECT biosensory devices.This work represents a generic protocol to develop the novel signal-on PEDOT:PSS OECT platform towards biochemical detection and beyond.展开更多
针对DV-HOP(distance vector hop)算法的定位精度对节点间跳数信息依赖性较强的特点,提出一种基于接收信号强度指示(received signal strength indicator,RSSI)每跳分级和平均跳距修正的DV-HOP改进算法RADV-HOP(RSSI and average hoppin...针对DV-HOP(distance vector hop)算法的定位精度对节点间跳数信息依赖性较强的特点,提出一种基于接收信号强度指示(received signal strength indicator,RSSI)每跳分级和平均跳距修正的DV-HOP改进算法RADV-HOP(RSSI and average hopping distance modifying DV-HOP)。仿真结果表明:在相同的网络环境里,与传统DV-HOP算法相比,RADV-HOP定位算法仅需节点通信芯片带有RSSI指示功能及增加少量的计算和通信开销,不需要额外的硬件开销,将每跳分为3个子级时,归一化定位误差能下降65%;与其他DV-HOP修正算法相比,RADV-HOP算法以相同的通信开销和稍微增加的计算开销使定位误差下降了45%。展开更多
基金supported by the National Natural Science Foundation of China(22034003,21974059,22174063)the Excellent Research Program of Nanjing University(ZYJH004)the State Key Laboratory of Analytical Chemistry for Life Science(5431ZZXM2203)。
文摘Herein we report a high-gain signal-on poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(PEDOT:PSS)organic electrochemical transistor(OECT)biosensing using an accumulation-mode PEDOT:PSS OECT modulated by a light-fueled MXene/MOFs/Ni O Schottky heterojunction.In such a system,the MXene/MOFs/Ni O Schottky heterojunction exhibited superior gating effect,as it not only enabled the fast-directional charge transfer but also guaranteed the maximal accessibility of the electrolyte to topped 2D MXene with large surface area.In linkage with a bi-enzyme cascade system,the quinone derivatives produced by the cascade reaction of alkaline phosphatase(ALP)and tyrosinase(TYR)could serve as effective electron acceptors for the representative Ti_(3)C_(2)/PCN-224/Ni O heterojunction,underpinning an innovative method for sensitive detection of ALP activity with a low detection limit of 0.001 U L^(-1).Remarkably,the as-developed system demonstrated a remarkable current gain as high as near 10^(4),which to our knowledge is the highest one among existing OECT biosensory devices.This work represents a generic protocol to develop the novel signal-on PEDOT:PSS OECT platform towards biochemical detection and beyond.
文摘针对DV-HOP(distance vector hop)算法的定位精度对节点间跳数信息依赖性较强的特点,提出一种基于接收信号强度指示(received signal strength indicator,RSSI)每跳分级和平均跳距修正的DV-HOP改进算法RADV-HOP(RSSI and average hopping distance modifying DV-HOP)。仿真结果表明:在相同的网络环境里,与传统DV-HOP算法相比,RADV-HOP定位算法仅需节点通信芯片带有RSSI指示功能及增加少量的计算和通信开销,不需要额外的硬件开销,将每跳分为3个子级时,归一化定位误差能下降65%;与其他DV-HOP修正算法相比,RADV-HOP算法以相同的通信开销和稍微增加的计算开销使定位误差下降了45%。
