Analysis of the Significance of Key Points of Patient Interventional Psychological Care and Pain Care

Interventional therapy has become increasingly popular in clinical practice due to advancements in medical technology.However,patients often experience psychological and physiological pressure due to its invasive nature.The management of patient discomfort and tension is crucial to ensure effective treatment.Psychological and pain management are essential components of interventional therapy,as they significantly impact patient recovery and prognosis.This article discussed the importance of interventional psychological and pain care for patients,starting with the development and spread of interventional therapy.The significance of providing high-quality nursing services to patients and improving their quality of life was also discussed.

Identification of metastasis-associated genes in colorectal cancer through an integrated genomic and transcriptomic analysis

Objective： Identification of colorectal cancer （CRC） metastasis genes is one of the most important issues in CRC research. For the purpose of mining CRC metastasis-associated genes, an integrated analysis of mJcroarray data was presented, by combined with evidence acquired from comparative genornic hybridization （CGH） data. Methods： Gene expression profile data of CRC samples were obtained at Gene Expression Omnibus （GEO） website. The 15 important chromosomal aberration sites detected by using CGH technology were used for integrated genomic and transcriptomic analysis. Significant Analysis of Microarray （SAM） was used to detect significantly differentially expressed genes across the whole genome. The overlapping genes were selected in their corresponding chromosomal aberration regions, and analyzed by using the Database for Annotation, Visualization and Integrated Discovery （DAVID）. Finally, SVM-T-RFE gene selection algorithm was applied to identify ted genes in CRC. Results： A minimum gene set was obtained with the minimum number [14] of genes, and the highest classification accuracy （100%） in both PRI and META datasets. A fraction of selected genes are associated with CRC or its metastasis. Conclusions- Our results demonstrated that integration analysis is an effective strategy for mining cancer- associated genes.

CLINICAL SIGNIFICANCE OF MEASURING SERUM IL-6 ACTIVITIES IN MULTIPLE MYELOMA AN ANALYSIS OF 81 CASES

Interleukin 6(IL-6) is known as hybridoma cell growth factor,B-cell differentiating factor and so on One of its important biological functions in to induce

SiZer for exploration of inhomogeneous structure in temporal distribution of earth-quakes

In this paper, the inhomogeneous structure of generalized seismic strain release time series (GSSRTS) of earth- quakes in East, West China and their subtectonic regions as Xinjiang, Qinghai-Xizang (Tibetan) Plateau, Northeast China, North China, South China and Taiwan have been analyzed by using the method of significant analysis on zero crossings of derivatives (SiZer). Results show that when index η for estimating GSSRTS is close to zero and bandwidth is large enough, GSSRTSs feature significant increasing in Xinjiang, Northeast China, South China and Taiwan tectonic regions and decreasing in Qinghai-Xizang (Tibetan Platean) and North China tectonic regions from January 1, 1970 to January 1, 2000. While with the dwindling of bandwidth GSSRTSs in all the above tec- tonic regions characterize clustering, that is to say, significant increasing and decreasing emerge alternatively. When η is large enough, GSSRTSs would have no significant statistical variation in most of above tectonic regions except Qinghai-Xizang (Tibetan Platean) and Taiwan where significant increasing or decreasing hold in several time intervals within limited bandwidths.

A Model for Capacity Considering the Interference by Pedestrian Traffic at Signal Intersections

The capacity is impacted badly by pedestrians' violation behavior at signal intersections. In order to quantify the impact,the time-headway and the vehicular speed from start-up to reach the stable saturation flow with and without pedestrian traffic are used as the direct measurements. Using the statistical analysis,the timeheadway of saturation flow is mainly affected by the position of pedestrians and the degree of pedestrians 'influence is classified into four levels. Then the speed-time profile for the vehicular acceleration at each level is fitted by Curve Fitting Software. Based on the effect to the time-headway and acceleration time,the model of capacity influenced by pedestrians is established and the influence is quantified, which enriches the fundamental theory of traffic engineering. The result shows that the vehicular capacity can be decreased by 14%at the worst case( level I). The conclusions obtained in this paper are valuable for better management of the signal intersection.