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Distributed Stochastic Optimization with Compression for Non-Strongly Convex Objectives
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作者 Xuanjie Li Yuedong Xu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第4期459-481,共23页
We are investigating the distributed optimization problem,where a network of nodes works together to minimize a global objective that is a finite sum of their stored local functions.Since nodes exchange optimization p... We are investigating the distributed optimization problem,where a network of nodes works together to minimize a global objective that is a finite sum of their stored local functions.Since nodes exchange optimization parameters through the wireless network,large-scale training models can create communication bottlenecks,resulting in slower training times.To address this issue,CHOCO-SGD was proposed,which allows compressing information with arbitrary precision without reducing the convergence rate for strongly convex objective functions.Nevertheless,most convex functions are not strongly convex(such as logistic regression or Lasso),which raises the question of whether this algorithm can be applied to non-strongly convex functions.In this paper,we provide the first theoretical analysis of the convergence rate of CHOCO-SGD on non-strongly convex objectives.We derive a sufficient condition,which limits the fidelity of compression,to guarantee convergence.Moreover,our analysis demonstrates that within the fidelity threshold,this algorithm can significantly reduce transmission burden while maintaining the same convergence rate order as its no-compression equivalent.Numerical experiments further validate the theoretical findings by demonstrating that CHOCO-SGD improves communication efficiency and keeps the same convergence rate order simultaneously.And experiments also show that the algorithm fails to converge with low compression fidelity and in time-varying topologies.Overall,our study offers valuable insights into the potential applicability of CHOCO-SGD for non-strongly convex objectives.Additionally,we provide practical guidelines for researchers seeking to utilize this algorithm in real-world scenarios. 展开更多
关键词 Distributed stochastic optimization arbitrary compression fidelity non-strongly convex objective function
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Large-field objective lens for multi-wavelength microscopy at mesoscale and submicron resolution
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作者 Xin Xu Qin Luo +7 位作者 Jixiang Wang Yahui Song Hong Ye Xin Zhang Yi He Minxuan Sun Ruobing Zhang Guohua Shi 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2024年第6期41-56,共16页
Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously anal... Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution. 展开更多
关键词 mesoscopic objective lens large field-of-view high resolution MULTI-WAVELENGTH wide-field microscopy confocal laser scanning microscopy
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Research on the Relationship between the School-Running Characteristics of Private Colleges and Universities and the Development Objectives of the Government
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作者 Lishuxian Zhao Xiaoxia Wu Zhuolin Zhu 《Journal of Contemporary Educational Research》 2024年第9期296-302,共7页
The development objectives of the Chinese government have a guiding effect on the school-running characteristics of private colleges and universities.This paper explores the relationship between the characteristics of... The development objectives of the Chinese government have a guiding effect on the school-running characteristics of private colleges and universities.This paper explores the relationship between the characteristics of private colleges and universities and the development objectives of the provincial government,using Jiangsu Province as a case study.All the schools have the consciousness of fully considering the development objectives of Jiangsu Province when formulating the school-running characteristics.Their characteristics all contain some training methods,training courses,or institutional construction aiming at the development objectives.Most universities can support the government’s objectives on employment and innovation.Only a third of the schools provide government support for science research.Private colleges and universities should make full use of the free and flexible advantages of private education,combine them with the continuous changes of policies and markets,and create clear,scientific,and dynamic school-running characteristics,in order to achieve long-term development. 展开更多
关键词 Development objectives of the government School-running characteristics Chinese Private colleges and universities
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Multi Objective Decision Making Method Based on Evaluation Criterion for Problems with Linear Value Function
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作者 蒋尚华 韩勇 徐南荣 《Journal of Southeast University(English Edition)》 EI CAS 1998年第1期114-121,共8页
A class of interactive multi objective decision making method by means of evaluation criterion is proposed for problems with linear value function,in which case,the decision maker(DM) usually has only unwhole infor... A class of interactive multi objective decision making method by means of evaluation criterion is proposed for problems with linear value function,in which case,the decision maker(DM) usually has only unwhole information of weights for objectives. The concept of fault measure of the evaluation criterion is proposed to measure the deviation of the evaluation criterion from the DMs preference structure.The approach to obtain an upper boundary of fault measure of an evaluation criterion,and the approach to modify the evaluation criterion to be one with smaller fault measure,and the approach to obtain a pre optimized objective set by evaluation criterion with certain fault measure are also proposed. 展开更多
关键词 multi objective decision making evaluation criterion fault measure of evaluation criterion pre optimized objective set
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Effect of low-degree astigmatism on the objective visual quality
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作者 Ling-Ying Ye Shu-Feng Li +2 位作者 Jing-Jing Zuo Jin Li Hui-Xiang Ma 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第6期1086-1093,共8页
AIM:To evaluate the effect of low-degree astigmatism on objective visual quality through the Optical Quality Analysis System(OQAS).METHODS:This study enrolled 46 participants(aged 23 to 30y,90 eyes)with normal or corr... AIM:To evaluate the effect of low-degree astigmatism on objective visual quality through the Optical Quality Analysis System(OQAS).METHODS:This study enrolled 46 participants(aged 23 to 30y,90 eyes)with normal or corrected-to-normal vision.The cylindrical lenses(0,0.5,0.75,1.0,and 1.25 D)were placed at the axial direction(180°,45°,90°,and 135°)in front of the eyes with the best correction to form 16 types of regular low-degree astigmatism.OQAS was used to detect the objective visual quality,recorded as the objective scattering index(OSI),OQAS values at contrasts of 100%,20%,and 9%predictive visual acuity(OV100%,OV20%,and OV9%),modulation transfer function cut-off(MTFcut-off)and Strehl ratio(SR).The mixed effect linear model was used to compare objective visual quality differences between groups and examine associations between astigmatic magnitude and objective visual quality parameters.RESULTS:Apparent negative relationships between the magnitude of low astigmatism and objective visual quality were observed.The increase of OSI per degree of astigmatism at 180°,45°,90°,and 135°axis were 0.38(95%CI:0.35,0.42),0.50(95%CI:0.46,0.53),0.49(95%CI:0.45,0.54)and 0.37(95%CI:0.34,0.41),respectively.The decrease of MTFcut-off per degree of astigmatism at 180°,45°,90°,and 135°axis were-10.30(95%CI:-11.43,-9.16),-12.73(95%CI:-13.62,-11.86),-12.75(95%CI:-13.79,-11.70),and-9.97(95%CI:-10.92,-9.03),respectively.At the same astigmatism degree,OSI at 45°and 90°axis were higher than that at 0°and 135°axis,while MTFcut-off were lower.CONCLUSION:Low astigmatism of only 0.50 D can significantly reduce the objective visual quality. 展开更多
关键词 low-degree astigmatism objective visual quality Optical Quality Analysis System
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Eclipse计划系统MU Objective工具在鼻咽癌容积调强放射治疗计划中的应用研究
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作者 陈宗友 曾华驱 +5 位作者 汤树奎 林启富 梁柱 赖春任 赵善辉 温尊北 《中国医学装备》 2023年第10期53-60,共8页
目的:探讨Varian Eclipse计划系统MU Objective工具在鼻咽癌容积调强放射治疗(VMAT)计划中的应用,旨在保证治疗计划质量的同时降低治疗计划的机器跳数(MU)。方法:选取已接受容积调强放射治疗技术的21例鼻咽癌患者,在未使用MU Objective... 目的:探讨Varian Eclipse计划系统MU Objective工具在鼻咽癌容积调强放射治疗(VMAT)计划中的应用,旨在保证治疗计划质量的同时降低治疗计划的机器跳数(MU)。方法:选取已接受容积调强放射治疗技术的21例鼻咽癌患者,在未使用MU Objective工具的情况下给每例患者设计治疗参考计划(MU_(ref));将使用MU Objective工具对MU_(ref)进行重新优化,分别设置MU_(ref)的MU的30%、50%、70%、90%和120%,分别命名为MU_(30%)、MU_(50%)、MU_(70%)、MU_(90%)和MU_(120%)。将治疗计划MU_(30%)、MU_(50%)、MU_(70%)、MU_(90%)和MU_(120%)分别与MU_(ref)进行配对t检验统计分析,比较两种治疗计划的靶区、危及器官(OAR)剂量分布和计划的MU。结果:使用MU Objective工具对参考计划优化MU后,与参考计划相比部分靶区和OAR剂量体积参数差异虽有统计学意义,但无临床意义。治疗计划参数为MU_(30%)、MU_(50%)、MU_(70%)和MU_(90%)时,与MU_(ref)比较计划MU平均分别减少21.5%、19.5%、16.6%和8%,差异有统计学意义(t=9.652,t=8.843,t=8.963,t=11.323;P<0.05)。在MU_(120%)时,治疗计划MU平均增加1.7%,但未显著提高靶区剂量覆盖。结论:对于鼻咽癌VMAT计划,使用Eclipse计划系统的MU Objective工具在减少计划MU的同时可获得与参考计划相似的剂量分布。MU Objective工具可作为鼻咽癌或其他部位VMAT计划的常规使用工具,以保证计划质量同时减少放射治疗计划的MU。 展开更多
关键词 容积调强放射治疗(VMAT) Eclispe计划系统 MU objective工具 机器跳数(MU)
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MULTI OBJECTIVE OPTIMIZATION USING GENETIC ALGORITHM WITH LOCAL SEARCH
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作者 戴晓晖 李敏强 寇纪淞 《Transactions of Tianjin University》 EI CAS 1998年第2期31-35,共5页
In this paper,we propose a hybrid algorithm for finding a set of non dominated solutions of a multi objective optimization problem.In the proposed algorithm,a local search procedure is applied to each solution gener... In this paper,we propose a hybrid algorithm for finding a set of non dominated solutions of a multi objective optimization problem.In the proposed algorithm,a local search procedure is applied to each solution generated by genetic operations.The aim of the proposed algorithm is not to determine a single final solution but to try to find all the non dominated solutions of a multi objective optimization problem.The choice of the final solution is left to the decision makers preference.High search ability of the proposed algorithm is demonstrated by computer simulation. 展开更多
关键词 multi objective genetic algorithm Pareto set local search
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Applications of Chemical Learning Evaluation Based on Bloom's Taxonomy of Educational Objectives
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作者 Chaojie Yang Duijun Zhang Yajing Lu Fujun Ma 《Journal of Chemistry and Chemical Engineering》 2012年第5期495-498,共4页
In this paper, Law of Conservation of Mass ("The Law"), one content standard of junior middle school chemistry, was decomposed based on The Revision of Bloom's Taxonomy of Educational Objectives ("The Revision... In this paper, Law of Conservation of Mass ("The Law"), one content standard of junior middle school chemistry, was decomposed based on The Revision of Bloom's Taxonomy of Educational Objectives ("The Revision") and placed in the classification table. In order to understand the teaching objectives more, the relationship between the related activities was studied. Teachers can design the teaching plans based on teaching objective, and determine different evaluations method according to different types of teaching objectives. It will raise students more cognitive activities and promote targeted objectives teaching. 展开更多
关键词 Bloom's Taxonomy of Educational objectives chemical teaching teaching objectives.
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Spatial Distribution of Halite in Kuqa Basin from Paleogene to Neogene and Signification of Potash Survey 被引量:2
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作者 CAO Yangtong LIU Chenglin +1 位作者 JIAO Pengcheng TANG Min 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2014年第S1期203-203,共1页
Evaporites with gigantic thickness had been developed in Kuqa Basin from Paleocene to early Miocene,and the sediment thickness changed from tens to thousands of meters.By 3D mine software,spatial distribution model of
关键词 Kuqa Basin HALITE spatial distribution model signification of potash survey
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Reactor Network Synthesis Based on Instantaneous Objective Function Characteristic Curves 被引量:2
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作者 张治山 赵文 +2 位作者 王艳丽 周传光 袁希钢 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2003年第4期436-440,共5页
It is believed that whether the instantaneous objective function curves of plug-flow-reactor (PFR) and continuous-stirred-tank-reactor (CSTR) overlap or not, they have a consistent changing trend for complex reactions... It is believed that whether the instantaneous objective function curves of plug-flow-reactor (PFR) and continuous-stirred-tank-reactor (CSTR) overlap or not, they have a consistent changing trend for complex reactions (steady state, isothermal and constant volume). As a result of the relation of the objective functions (selectivity or yield) to the instantaneous objective functions (instantaneous selectivity or instantaneous reaction rate), the optimal reactor network configuration can be determined according to the changing trend of the instantaneous objective function curves. Further, a recent partition strategy for the reactor network synthesis based on the instantaneous objective function characteristic curves is proposed by extending the attainable region partition strategy from the concentration space to the instantaneous objective function-unreacted fraction of key reactant space. In this paper, the instantaneous objective function is closed to be the instantaneous selectivity and several samples are examined to illustrate the proposed method. The comparison with the previous work indicates it is a very convenient and practical systematic tool of the reactor network synthesis and seems also promising for overcoming the dimension limit of the attainable region partition strategy in the concentration space. 展开更多
关键词 reactor network synthesis instantaneous objective function PARTITION
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A Sound Quality Objective Evaluation Method Based on Auditory Peripheral Simulation Model 被引量:1
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作者 Yinhan Gao~1,Jun Xie~2,Jie Liang~1,Xin Chang~3,Baojun Wu~2 1.Experimental Centre of Testing Science,Jilin University,Changchun 130022,P.R.China 2.College of Instrumentation & Electrical Engineering,Jilin University,Changchun 130061,P.R.China 3.Laboratory of Applications and Computations in Electromagnetics and Optics,Department of Electrical Engineering, University of Washington,WA 98195-2500,USA 《Journal of Bionic Engineering》 SCIE EI CSCD 2010年第2期199-208,共10页
Based on auditory peripheral simulation model, a new Sound Quality Objective Evaluation (SQOE) method is presented,which can be used to model and analyze the impacts of head, shoulder and other parts of human body on ... Based on auditory peripheral simulation model, a new Sound Quality Objective Evaluation (SQOE) method is presented,which can be used to model and analyze the impacts of head, shoulder and other parts of human body on sound wave trans-mission.This method employs the artificial head technique, in which the head related transfer function was taken into account tothe outer ear simulation phase.First, a bionic artificial head was designed as the outer ear model with considering the outersound field in view of theory and physical explanations.Then the auditory peripheral simulation model was built, which mimicsthe physiological functions of the human hearing, simulating the acoustic signal transfer process and conversion mechanismsfrom the free field to the peripheral auditory system.Finally, performance comparison was made between the proposed SQOEmethod and ArtemiS software, and the verifications of subjective and objective related analysis were made.Results show thatthe proposed method was economical, simple, and with good evaluation quality. 展开更多
关键词 sound quality objective evaluation auditory peripheral simulation model artificial head head related transfer function
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OPTIMALITY CONDITIONS AND DUALITY RESULTS FOR NONSMOOTH VECTOR OPTIMIZATION PROBLEMS WITH THE MULTIPLE INTERVAL-VALUED OBJECTIVE FUNCTION 被引量:4
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作者 Tadeusz ANTCZAK 《Acta Mathematica Scientia》 SCIE CSCD 2017年第4期1133-1150,共18页
In this paper, both Fritz John and Karush-Kuhn-Tucker necessary optimality conditions are established for a (weakly) LU-efficient solution in the considered nonsmooth multiobjective programming problem with the mult... In this paper, both Fritz John and Karush-Kuhn-Tucker necessary optimality conditions are established for a (weakly) LU-efficient solution in the considered nonsmooth multiobjective programming problem with the multiple interval-objective function. Further, the sufficient optimality conditions for a (weakly) LU-efficient solution and several duality results in Mond-Weir sense are proved under assumptions that the functions constituting the considered nondifferentiable multiobjective programming problem with the multiple interval- objective function are convex. 展开更多
关键词 nonsmooth multiobjective programming problem with the multiple interval- objective function Fritz John necessary optimality conditions Karush-Kuhn- Tucker necessary optimality conditions (weakly) LU-efficient solution Mond- Weir duality
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A compound objective reconfiguration of distribution networks using hierarchical encoded particle swarm optimization 被引量:3
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作者 WEN Juan TAN Yang-hong +1 位作者 JIANG Lin XU Zu-hua 《Journal of Central South University》 SCIE EI CAS CSCD 2018年第3期600-615,共16页
With the development of automation in smart grids,network reconfiguration is becoming a feasible approach for improving the operation of distribution systems.A novel reconfiguration strategy was presented to get the o... With the development of automation in smart grids,network reconfiguration is becoming a feasible approach for improving the operation of distribution systems.A novel reconfiguration strategy was presented to get the optimal configuration of improving economy of the system,and then identifying the important nodes.In this strategy,the objectives increase the node importance degree and decrease the active power loss subjected to operational constraints.A compound objective function with weight coefficients is formulated to balance the conflict of the objectives.Then a novel quantum particle swarm optimization based on loop switches hierarchical encoded was employed to address the compound objective reconfiguration problem.Its main contribution is the presentation of the hierarchical encoded scheme which is used to generate the population swarm particles of representing only radial connected solutions.Because the candidate solutions are feasible,the search efficiency would improve dramatically during the optimization process without tedious topology verification.To validate the proposed strategy,simulations are carried out on the test systems.The results are compared with other techniques in order to evaluate the performance of the proposed method. 展开更多
关键词 distribution network reconfiguration node importance degree compound objective function hierarchical encoded
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基于Stingray Objective Studio的防空C^3I显控系统界面开发
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作者 狄博 李进 雷英杰 《弹箭与制导学报》 CSCD 北大核心 2005年第SA期456-457,466,共3页
文中提出了用 Stingray Objective Studio 工具集来进行防空显控系统界面开发,使得开发人员将大量的时间和精力用于系统结构和数据处理算法上,这样不光降低了开发难度,也增强了系统的功能和稳定性。
关键词 STINGRAY objective STUDIO 防空 C^3I 显控系统
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Research on the Curriculum Construction by Promoting Teaching Using Competition Based on Bloom's Taxonomy of Educational Objectives 被引量:2
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作者 Xiu LI Hui WANG 《Asian Agricultural Research》 2021年第12期49-52,共4页
Based on Bloom's taxonomy of educational objectives,this paper puts forward the construction of curriculum system in the primary stage,intermediate stage and advanced stage by promoting teaching using competition,... Based on Bloom's taxonomy of educational objectives,this paper puts forward the construction of curriculum system in the primary stage,intermediate stage and advanced stage by promoting teaching using competition,and provides a theoretical and practical basis for the curriculum construction by promoting teaching using competition,which is of great practical significance to promoting the construction of applied universities. 展开更多
关键词 Bloom's taxonomy of educational objectives Promoting teaching using competition Curriculum construction
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Development Progress of China’s First Mars Exploration Mission:Its Scientific Objectives and Payloads 被引量:1
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作者 JIA Yingzhuo ZOU Yongliao +4 位作者 ZHU Yan DU Qingguo FAN Yu CHEN Yuesong WANG Chi 《空间科学学报》 CAS CSCD 北大核心 2020年第5期693-697,共5页
China’s first Mars exploration mission is scheduled to be launched in 2020.It aims not only to conduct global and comprehensive exploration of Mars by use of an orbiter but also to carry out in situ observation of ke... China’s first Mars exploration mission is scheduled to be launched in 2020.It aims not only to conduct global and comprehensive exploration of Mars by use of an orbiter but also to carry out in situ observation of key sites on Mars with a rover.This mission focuses on the following studies:topography,geomorphology,geological structure,soil characteristics,water-ice distribution,material composition,atmosphere and ionosphere,surface climate,environmental characteristics,Mars internal structure,and Martian magnetic field.It is comprised of an orbiter,a lander,and a rover equipped with 13 scientific payloads.This article will give an introduction to the mission including mission plan,scientific objectives,scientific payloads,and its recent development progress. 展开更多
关键词 China’s first Mars exploration mission Scientific objectives Scientific payloads
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Ten Objective for Sustainable Development 被引量:1
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作者 Hu Angang 《China Population Today》 2000年第1期3-4,8,共3页
关键词 Ten objective for Sustainable Development
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Closed-loop supply chain network equilibrium strategy model with environmental protection objectives 被引量:1
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作者 Yang Liu Guitao Zhang 《Chinese Journal of Population,Resources and Environment》 2020年第3期251-261,共11页
With the increasing popularity of ecological civilization and sustainable development,enterprises should consider environmental protection measures in their operations in addition to pursue their economic interests.Th... With the increasing popularity of ecological civilization and sustainable development,enterprises should consider environmental protection measures in their operations in addition to pursue their economic interests.This paper establsihes a closed-loop supply chain network model composed of multiple suppliers,manufacturers,retailers,recyclers,and demand markets—regarding their dual goals of the profit maximization and the minimization of carbon emissions.The conditions necessary for establishing overall equilibrium and an equilibrium model of the entire closed-loop supply chain network are determined by applying variational inequality and dual theory.A modified projection contraction algorithm is used to design a model-solving program.Finally,using numerical examples,the paper conducts a comparative static analysis on important parameters such as the weight coefficients of environmental protection objectives and consumers'awareness of low-carbon environmental protection and attains some beneficial enlightenment on management.The results indicate that when the environmental protection objectives of a certain type of enterprise increases,both the economic benefits and environmental protection performance will improve;when the environmental protection objectives of all enterprises increases simultaneously,environmental protection performance improves significantly,but the changes in economic benefits of different enterprises are inconsistent and profit coordination is more complex.Although consumers’awareness of low-carbon preference could improve environmental performance,it reduces the overall profits of network members and the entire closed-loop supply chain network as a whole.The above conclusions can be used as a reference for the government in designing low-carbon environmental protection policy and in closed-loop supply chain research. 展开更多
关键词 Closed-loop supply chain network Environmental protection objectives Nash equilibrium Multi-objective decision-making Environmental protection awareness of consumers
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A Primal-Dual Infeasible-Interior-Point Algorithm for Multiple Objective Linear Programming Problems
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作者 HUANGHui FEIPu-sheng YUANYuan 《Wuhan University Journal of Natural Sciences》 CAS 2005年第2期351-354,共4页
A primal-dual infeasible interior point algorithm for multiple objective linear programming (MOLP) problems was presented. In contrast to the current MOLP algorithm. moving through the interior of polytope but not con... A primal-dual infeasible interior point algorithm for multiple objective linear programming (MOLP) problems was presented. In contrast to the current MOLP algorithm. moving through the interior of polytope but not confining the iterates within the feasible region in our proposed algorithm result in a solution approach that is quite different and less sensitive to problem size, so providing the potential to dramatically improve the practical computation effectiveness. 展开更多
关键词 Key words multiple objective linear programming primal dual infeasible INTERIOR point algorithm
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Multiple Objective Test Design for Accelerated Destructive Degradation Tests
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作者 黄硕 杨军 +1 位作者 彭锐 赵宇 《Journal of Donghua University(English Edition)》 EI CAS 2015年第6期954-956,共3页
Accelerated destructive degradation tests(ADDTs)are powerful to provide reliability information in the degradation processes with destructive measurements.In order to carry out an ADDT efficiently,both the estimation ... Accelerated destructive degradation tests(ADDTs)are powerful to provide reliability information in the degradation processes with destructive measurements.In order to carry out an ADDT efficiently,both the estimation precision of parameters and the test cost should be considered.On the basis of the given degradation model and failure criterion,a multiple-objective optimization model for the design of ADDTs is proposed.Under constrains of the maximum measurement time,the total sample size and the number of stress levels,a comprehensive target function is suggested to reflect both the precision of lifetime estimation and total cost,and the optimal test plan is obtained,which is composed by optimal choices for samples size,measurement frequency,and the number of measurements at each stress level.A real example is illustrated to demonstrate the implementation of the proposed approach. 展开更多
关键词 accelerated destructive degradation tests(ADDTs) highly reliable products multiple objectives test cost asymptotic variance
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