Objective: To develop the representative fingerprint for the quality control of placenta polypeptide injection. Methods: The chromatographic separation was performed using a Phenomenex Gemini C18 column (250 mm 4.6 mm...Objective: To develop the representative fingerprint for the quality control of placenta polypeptide injection. Methods: The chromatographic separation was performed using a Phenomenex Gemini C18 column (250 mm 4.6 mm, 5 mm) maintained at 30 1C. 0.1% aqueous trifiuoroacetic acid (Solvent A) and acetonitrile contained 0.1% TFA (Solvent B) were used as mobile phase with a gradient elution. Detection wavelength was 280 nm with the sample injection volume of 50 mL; the fiow rate was 1.0 mL/min. The fingerprints of different samples were investigated by similarity analysis. Results: Nine peaks were identified as the characteristic common peaks. The similarities of the fingerprints of the 10 batches of samples were above 0.992. Conclusion: This method showed high precision and good repeatability, and provided the basis for the improvement of the quality control of placenta polypeptide injection.展开更多
Background:Active video games are a new method for increasing physical activity(PA).Fully immersive virtual reality(VR)is a hardware device on which an active video game can run.Active(video games in)VR(AVR),might inc...Background:Active video games are a new method for increasing physical activity(PA).Fully immersive virtual reality(VR)is a hardware device on which an active video game can run.Active(video games in)VR(AVR),might increase immersion,game engagement,and moderate-to-vigorous PA(MVPA),thereby yielding greater exercise-related benefits,e.g.,cognitive performance.Methods:We examined the induction of MVPA via an AVR and a sedentary VR(SVR)as well as the effects of VR play on cognitive performance,which was monitored using 2 different methods.Each of 29 sedentary college students attended three 20-min laboratory sessions(AVR,SVR,or control)in a randomized order;during the control session,they sat quietly doing nothing.A fully immersive headset was used for the 2 video game sessions.We monitored and computed participants’PA using hip-wom accelerometers(wGT3 x-bt;ActiGraph,Pensacola,FL,USA)and a heart rate band(Polar H7;Polar,Kempele,Finland).After each session,the participants completed a mnemonic similarity test(MST)to measure recognition memory.They also filled out a motion sickness questionnaire and an abbreviated game experience questionnaire.Results:The AVR session induced a significantly greater heart rate and more time spent in MVPA than did either of the other 2 sessions regardless of the PA monitoring method.AVR elicited greater game experience questionnaire-assessed sensory and imaginative immersion,challenge,and positive affect than did SVR.The mnemonic similarity test recognition score was marginally higher post-AVR session than it was post-SVR session.Conclusion:AVR elicited MVPA without a significant increase in motion sickness and induced a better game experience and better borderline cognitive performance than did SVR.展开更多
A large number of high-voltage power transmission towers have recently been constructed in mining areas prone to subsidence. In order to ensure the safety of the transmission towers and the safe operation of transmiss...A large number of high-voltage power transmission towers have recently been constructed in mining areas prone to subsidence. In order to ensure the safety of the transmission towers and the safe operation of transmission systems, it is imperative to carry out research on the anti-deformation performance of transmission towers. In our study, we performed experiments on the anti-deformation performance of a transmission tower in a subsidence area on a scale model with a geometric scale ratio of 1:5 and analyzed the failure mechanism of the tower members. The results show that, when the axial distance between two supports changes, destabilization failure most likely occurs in the members of the bottom transverse layer because some parts of the main diagonal member bars yield under the action of compression. The failure mechanism of the tower members basically coincides with the lever principle.展开更多
为提高机场运行效率评价结果的科学性和全面性,提出了一种基于组合赋权-TOPSIS(technique for order performance by similarity to ideal solution)模型的机场运行效率评价方法。从机位运行效率、旅客登机效率、飞机滑行效率和协同效率...为提高机场运行效率评价结果的科学性和全面性,提出了一种基于组合赋权-TOPSIS(technique for order performance by similarity to ideal solution)模型的机场运行效率评价方法。从机位运行效率、旅客登机效率、飞机滑行效率和协同效率4个维度出发,构建了由航班靠桥率、廊桥周转率、机位变更比例等11个指标组成的机场运行效率评价体系;利用G1法、熵权法分别计算评价指标主观和客观权重,以最小化主客观加权属性偏离程度为目标计算组合权重;使用TOPSIS计算待评价机场综合评价指数。利用该模型分析国内3类共8家机场的运行效率,可以得到各评价对象的运行效率等级和综合排名。结果表明:该模型能够有效探明影响机场运行效率的主要因素,具有一定的参考价值。展开更多
文摘Objective: To develop the representative fingerprint for the quality control of placenta polypeptide injection. Methods: The chromatographic separation was performed using a Phenomenex Gemini C18 column (250 mm 4.6 mm, 5 mm) maintained at 30 1C. 0.1% aqueous trifiuoroacetic acid (Solvent A) and acetonitrile contained 0.1% TFA (Solvent B) were used as mobile phase with a gradient elution. Detection wavelength was 280 nm with the sample injection volume of 50 mL; the fiow rate was 1.0 mL/min. The fingerprints of different samples were investigated by similarity analysis. Results: Nine peaks were identified as the characteristic common peaks. The similarities of the fingerprints of the 10 batches of samples were above 0.992. Conclusion: This method showed high precision and good repeatability, and provided the basis for the improvement of the quality control of placenta polypeptide injection.
基金supported in part by a grant from the National Institute of Diabetes and Digestive and Kidney Diseases(R01DK109316,principle investigator:ASL)by the College of Arts,Media,and Design,Bouve College of Health Sciences at Northeastern University,Boston,MA,USA。
文摘Background:Active video games are a new method for increasing physical activity(PA).Fully immersive virtual reality(VR)is a hardware device on which an active video game can run.Active(video games in)VR(AVR),might increase immersion,game engagement,and moderate-to-vigorous PA(MVPA),thereby yielding greater exercise-related benefits,e.g.,cognitive performance.Methods:We examined the induction of MVPA via an AVR and a sedentary VR(SVR)as well as the effects of VR play on cognitive performance,which was monitored using 2 different methods.Each of 29 sedentary college students attended three 20-min laboratory sessions(AVR,SVR,or control)in a randomized order;during the control session,they sat quietly doing nothing.A fully immersive headset was used for the 2 video game sessions.We monitored and computed participants’PA using hip-wom accelerometers(wGT3 x-bt;ActiGraph,Pensacola,FL,USA)and a heart rate band(Polar H7;Polar,Kempele,Finland).After each session,the participants completed a mnemonic similarity test(MST)to measure recognition memory.They also filled out a motion sickness questionnaire and an abbreviated game experience questionnaire.Results:The AVR session induced a significantly greater heart rate and more time spent in MVPA than did either of the other 2 sessions regardless of the PA monitoring method.AVR elicited greater game experience questionnaire-assessed sensory and imaginative immersion,challenge,and positive affect than did SVR.The mnemonic similarity test recognition score was marginally higher post-AVR session than it was post-SVR session.Conclusion:AVR elicited MVPA without a significant increase in motion sickness and induced a better game experience and better borderline cognitive performance than did SVR.
基金the National Natural Science Foundation of China (No. 50004008)the Science Fund of China University of Mining and Technology (No. OB061045)
文摘A large number of high-voltage power transmission towers have recently been constructed in mining areas prone to subsidence. In order to ensure the safety of the transmission towers and the safe operation of transmission systems, it is imperative to carry out research on the anti-deformation performance of transmission towers. In our study, we performed experiments on the anti-deformation performance of a transmission tower in a subsidence area on a scale model with a geometric scale ratio of 1:5 and analyzed the failure mechanism of the tower members. The results show that, when the axial distance between two supports changes, destabilization failure most likely occurs in the members of the bottom transverse layer because some parts of the main diagonal member bars yield under the action of compression. The failure mechanism of the tower members basically coincides with the lever principle.
文摘为提高机场运行效率评价结果的科学性和全面性,提出了一种基于组合赋权-TOPSIS(technique for order performance by similarity to ideal solution)模型的机场运行效率评价方法。从机位运行效率、旅客登机效率、飞机滑行效率和协同效率4个维度出发,构建了由航班靠桥率、廊桥周转率、机位变更比例等11个指标组成的机场运行效率评价体系;利用G1法、熵权法分别计算评价指标主观和客观权重,以最小化主客观加权属性偏离程度为目标计算组合权重;使用TOPSIS计算待评价机场综合评价指数。利用该模型分析国内3类共8家机场的运行效率,可以得到各评价对象的运行效率等级和综合排名。结果表明:该模型能够有效探明影响机场运行效率的主要因素,具有一定的参考价值。
