On April 12,the National Youth Council of Singapore and the All-China Youth Federation jointly hosted the Second China-Singapore Youth Development Forum in Singapore.Themed"Youth Leadership and Sustainable Develo...On April 12,the National Youth Council of Singapore and the All-China Youth Federation jointly hosted the Second China-Singapore Youth Development Forum in Singapore.Themed"Youth Leadership and Sustainable Development",this forum was one of the major events of the China-Singapore Youth Leaders Exchange Camp.Ye Cong,Vice-Chairman of the All-China Youth Federation,and David Chua,Executive President of the National Youth Council of Singapore,attended the forum and delivered a speech respectively.Zhu Jing,Minister Counselor of the Chinese Embassy in Singapore,and nearly 100 Chinese and Singaporean youth representatives from various fields attended the forum.展开更多
On April 27,the World Tai Chi Day-Tai Chi lecture and experience event,sponsored by China Cultural Center in Singapore and supported by the Bank of China Singapore Branch,ICBC Singapore Branch,Singapore International ...On April 27,the World Tai Chi Day-Tai Chi lecture and experience event,sponsored by China Cultural Center in Singapore and supported by the Bank of China Singapore Branch,ICBC Singapore Branch,Singapore International Wushu Cultural Centre,and Singapore Youth Culture&Arts Centre,was successfully held at China Cultural Center in Singapore.展开更多
From September 8 to 9,Singapore's Foreign Minister Vivian Balakrishnan made an official visit to Beijing.It was the first visit by a Singaporean Foreign Minister to China since new Prime Minister Lawrence Wong suc...From September 8 to 9,Singapore's Foreign Minister Vivian Balakrishnan made an official visit to Beijing.It was the first visit by a Singaporean Foreign Minister to China since new Prime Minister Lawrence Wong succeeded Lee Hsien Loong.It was also the inaugural visit under an annual exchange mechanism between the ruling parties of both countries,which has been groundbreaking and exerted a positive influence on China-Singapore cooperation and regional development.展开更多
The initial segment of this paper scrutinizes Descente’s promotional strategy for its training shoes in the Singapore market.Subsequently,the introduction section provides a brief overview on Descente’s products,emp...The initial segment of this paper scrutinizes Descente’s promotional strategy for its training shoes in the Singapore market.Subsequently,the introduction section provides a brief overview on Descente’s products,emphasizing the age demographic of the product’s consumer base in Singapore,preferred purchasing channels and consumer behavior tendencies.This serves as a precursor to the main body of the article.Within the main body,the paper delves into an analysis of the primary marketing strategies,along with a detailed examination of specific operational implementation.Finally,the article concludes by summarizing key insights and evaluating their impact within the marketing domain.展开更多
Three new species of Orthogonius Macleay (Coleoptera, Caraboidea) from Malaya Peninsula are described and illustrated in the present papr: O. solidicornis, sp. nov. (from Singapore), O. morvani, sp. nov. and O. thaicu...Three new species of Orthogonius Macleay (Coleoptera, Caraboidea) from Malaya Peninsula are described and illustrated in the present papr: O. solidicornis, sp. nov. (from Singapore), O. morvani, sp. nov. and O. thaicus, sp. nov. (from Thailand).展开更多
为比较星洲红鱼(Singapore red tilapia)和奥尼罗非鱼(Oreochromis niloticus)的生长和肌肉营养特性,实验利用两种鱼的不同体色将其混养在同一池塘中,在相同的环境条件和养殖管理下研究其生长特性,并分析肌肉营养成分。结果表明:两种罗...为比较星洲红鱼(Singapore red tilapia)和奥尼罗非鱼(Oreochromis niloticus)的生长和肌肉营养特性,实验利用两种鱼的不同体色将其混养在同一池塘中,在相同的环境条件和养殖管理下研究其生长特性,并分析肌肉营养成分。结果表明:两种罗非鱼生长在前60 d无差异,60 d后星洲红鱼的体长、体质量日增长和特定生长率均大于奥尼罗非鱼,且差异显著(P<0.05)。据此得到了星洲红鱼和奥尼罗非鱼的体长(L)、体质量(W)生长与养殖天数(d)的回归方程。星洲红鱼含肉率高于奥尼罗非鱼9.65%(P<0.05),肌肉水分高于奥尼罗非鱼,蛋白质、粗脂肪和灰分含量均低于奥尼罗非鱼,其中脂肪含量差异显著(P<0.05),其他不显著。两种罗非鱼肌肉的氨基酸组成全面,氨基酸组成均符合FAO/WHO的理想模式,除精氨酸含量有差异外,其他氨基酸含量稍有差异但不显著。星洲红鱼和奥尼罗非鱼肌肉EAA/TAA、EAA/NEAA、DAA/TAA和EAAI分别为41.04%和40.95%,70.00%和69.34%,40.71%和39.08%,67.46%和67.08%,差异不显著。星洲红鱼、奥尼罗非鱼肌肉∑SFA和∑UFA分别为28.03%和28.60%,63.87%和61.38%,各脂肪酸含量除C14:0和C18:2外,其他含量差异不显著。研究表明,星洲红鱼和奥尼罗非鱼生长快、营养丰富、食用价值高,是优质淡水鱼类养殖品种,其中星洲红鱼含肉率高,生长快,养殖效益明显。展开更多
Language planning plays a very important role in this world of globalization and multilingualism.With globalization,English has become a lingua franca for the whole world,whereas there seems to be an urgent need to pr...Language planning plays a very important role in this world of globalization and multilingualism.With globalization,English has become a lingua franca for the whole world,whereas there seems to be an urgent need to preserve and protect local languages and cultures.How to linguistically achieve the aim of unity in diversity is of great significance to both linguists and soci?olinguists.This article intends to explore how to create a harmonious language ecology.From the perspective of language ecolo?gy,the article firstly discusses such issues as language planning and Language Ecology.It is then dedicated to the study of language planning and policy in Singapore by giving an account of the development of language policy in Singapore,how various languag?es coexist harmoniously,its bilingual policy,and illustrating how multilingualism and multiculturalism have been successfully prac?ticed in Singapore.Finally,some implications for language planning in China in dealing with the protection of minority languag?es,and solutions to intractable language problems in the execution of One Belt One Road policy are provided.展开更多
A critical review is given on Singapore English. The historical introduction of the language provides readers a longitu dinal insight into the development of this special variety. Then, the language features of Colloq...A critical review is given on Singapore English. The historical introduction of the language provides readers a longitu dinal insight into the development of this special variety. Then, the language features of Colloquial Singapore English and Stan dard Singapore English are discussed, and a comparison of the use of Singapore and standard British English is made to show the differences in grammatical and lexical features of these two varieties of English.展开更多
Objectives:To investigate the experience of newly graduated registered nurses(NGRNs)in Singapore following their initial 6-12 months of transition from nursing student to registered nurse.Methods:This mixed-methods st...Objectives:To investigate the experience of newly graduated registered nurses(NGRNs)in Singapore following their initial 6-12 months of transition from nursing student to registered nurse.Methods:This mixed-methods study consisted of two phases.In the first phase,data were collected via the administration of the online survey to 30 NGRNs.The questionnaire contained 42 items of the fourpoint Likert scale survey.In the second phase,a focus group interview was conducted with 5 NGRNs to gather complementary information regarding the major findings from the first phase.Results:The survey revealed despite most NGRNs(80%)in this study expressed overall satisfied with their transition,the item score was(2.97±0.61)out of 4,the majority(83.3%)also perceived their transition to professional practice being stressful,the item score was(3.07±0.74)out of 4.Three themes emerged from the interview,'personal transition experience','professional transition experience',and'organizational transition experience',which are entwined to construct overall NGRNs'transition experiences.Conclusions:This study reaffirms the theory-practice gap phenomenon.This signifies the need for closer collaboration between educational,healthcare industry and regulatory stakeholders to examine and address factors that influence their transition experience to better support them for workforce readiness.展开更多
With continual population growth in the densely populated cities,e.g.,Singapore,traffic congestion is the main transportation problem.As such,Public Transport is deemed as the most sustainable mode of transport.Howeve...With continual population growth in the densely populated cities,e.g.,Singapore,traffic congestion is the main transportation problem.As such,Public Transport is deemed as the most sustainable mode of transport.However,pubic transport is often plagued with the First and Last Mile Problem(FLMP),reducing its appeal especially in the densely populated city areas.The FLMP leads to a wide range of complications,in particular,human congestion in public transport.In this research,after a comprehensive discussion of FLMP problem in densely populated city areas,a case study in Singapore,i.e.,the Kent Ridge Campus of National University of Singapore(KRC-NUS),has been conducted based on the survey and spatio-temporal analyses.In addition to the investigation of FLMP status in the case study area,a new campus shuttle bus route from an alternative MRT station(Haw Par Villa Station)has also been proposed based on the Tabu Search to alleviate the human congestion and current FLMP status for KRC-NUS.This research not only has successfully addressed the FLMP in the case study area,but also can be a good reference for other areas in densely populated cities to help mitigate FLMPs.展开更多
The Singapore seismic network and the seismicity of Singapore are briefly described, the four tremor events experienced by Singapore are discussed and the ground responses of different stations are compared. The tremo...The Singapore seismic network and the seismicity of Singapore are briefly described, the four tremor events experienced by Singapore are discussed and the ground responses of different stations are compared. The tremor incident standing operation procedure is also presented.展开更多
Burgeoning population and rapid urbanisation have contributed to two challenges facing cities today:food security and an increasing carbon footprint due to food imports.This paper examines the viability of rooftop far...Burgeoning population and rapid urbanisation have contributed to two challenges facing cities today:food security and an increasing carbon footprint due to food imports.This paper examines the viability of rooftop farming in urban centres in Asia.A context-specific exploration—sited in Singapore—looks at the challenges of building integrated agriculture.Findings suggest that Singapore’s public housing estates are suitable for rooftop farming.Implemented nationwide,such a scheme could result in a 700%increase in domestic vegetable production,satisfying domestic demand by 35.5%.Reducing food imports would also decrease Singapore’s carbon footprint by 9,052 tonnes of emissions annually.展开更多
Background:Varicella outbreaks occur frequently in closed environments such as those of militaries.This paper compares the economic outcomes of varicella vaccination in enlisted servicemen without prior reported varic...Background:Varicella outbreaks occur frequently in closed environments such as those of militaries.This paper compares the economic outcomes of varicella vaccination in enlisted servicemen without prior reported varicella infection or vaccination.Methods:We analyzed the economic outcomes of a varicella vaccination program on all enlisted servicemen without prior reported varicella infection or vaccination in the Singapore Armed Forces(SAF) between December 11,2010–December 20,2013,compared with the previous program of varicella vaccination only for selected personnel between December 1,2007–December 10,2010.Results:In the at-risk population of all active SAF servicemen,the program of varicella vaccination for all servicemen without prior reported varicella infection or vaccination upon enlistment would save 72.0 work days per 1000(95% CI:61.2-82.9),valued at SG$6,544 per 1000(95% CI:6,524-6,564),i.e.,costing SG$91.5 per work day saved(95% CI:78.7-107.3).This also results in a reduction of 2.7 varicella cases per 1000 and 5.43 outbreaks per 10000,or a total savings of SG$1,695 per 1000(95% CI:–2,730-6,834),taking into account the cost of work days lost over a three-year period,compared with the previous regime of vaccinations only for selected individuals.Conclusion:The varicella vaccination strategy targeting all enlisted servicemen without prior reported varicella infection or vaccination is able to prevent varicella infections and outbreaks,thus reducing absenteeism and days lost.展开更多
Following the success of the maiden World Refracto-ry Congress 2002, Worldrefractories Pte Ltd is pleased toannounce their next major global event-World RefractoryCongress 2004 which will bring forth discussions on is...Following the success of the maiden World Refracto-ry Congress 2002, Worldrefractories Pte Ltd is pleased toannounce their next major global event-World RefractoryCongress 2004 which will bring forth discussions on issuesrelating to business, commercial and the latest technologi-cal developments in the refractory and allied industries展开更多
BACKGROUND Invasive lobular carcinomas(ILC)form 5%-10%of breast cancer and rarely show overexpression of human epidermal growth factor receptor 2(HER2).AIM To describe the prevalence and prognostic factors of HER2 pos...BACKGROUND Invasive lobular carcinomas(ILC)form 5%-10%of breast cancer and rarely show overexpression of human epidermal growth factor receptor 2(HER2).AIM To describe the prevalence and prognostic factors of HER2 positive(HER2+)ILC in an Asian population.METHODS A retrospective review of patients with ILC seen between January 1985 and March 2018 at various SingHealth medical institutions was conducted.Demographic and clinical data were collected from medical records.We examined clinicopathological characteristics and survival in relation to HER2 status.RESULTS A total of 864 patients were included.Prevalence of HER2 positivity was 10.1%(87 patients).Compared with HER2 negative(HER2-)ILC,HER2+ILC was associated with a higher proportion of estrogen receptor negative(24.4%vs 5.9%,P<0.001),progesterone receptor negative(PR-)(40.2%vs 24%,P=0.002)and grade 3 tumours(Grade 3,29.0%vs 10.2%,P<0.001).Overall survival rate was poorer in patients with HER2+compared to HER2-ILC(56.7%vs 72.9%alive at 10 years;hazard ratio 1.87,95%confidence interval:1.21-2.90,P=0.004).Based on multivariate analysis,negative prognostic factors for overall survival included HER2 positivity,PR negativity,older age,Indian ethnicity and higher tumour stage.CONCLUSION Prevalence of HER2+ILC was 10.1%.HER2+ILC was more likely to have poorer prognostic features such as estrogen receptor negative,PR-and higher tumour grade,and have a poorer survival.展开更多
Aims:This study aim to gain insights into attitudes,acceptance and knowledge levels among family physicians toward homosexual people,which are important as they may affect care among this at-risk group.Methods:An anon...Aims:This study aim to gain insights into attitudes,acceptance and knowledge levels among family physicians toward homosexual people,which are important as they may affect care among this at-risk group.Methods:An anonymized self-administered questionnaire in English was posted with the assistance of the College of Family Physicians Singapore in February 2015 to its 1529 members with self-addressed,pre-stamped envelopes for replies.The questionnaire included demographic questions such as age group,gender,religion,ethnicity,marital status and place of practice.Questions and scales that measured attitude,acceptance,knowledge and perception of colleagues who are homosexual were also included in the questionnaire.Results:451 responses(29.5%)were obtained,of which 441 were valid(28.84%).About 52.8%of participants were found to have negative,8.9%neutral and 38.3%positive attitudes toward homosexuality.Most(75.6%)were accepting of homosexuals,with 9.3%neutral and 15.1%not accepting.Knowledge levels were poor,with a mean score of 6.9 out of a maximum of 13.A strong correlation was found between the attitudes towards lesbians and gay men(ATLG)and acceptance of homosexuals scales(r=0.69,P<0.001),with moderate correlations between acceptance and knowledge(r=0.54,P<0.001)and ATLG and Knowledge(r=0.54,P<0.001).Conclusion:Despite majority of family physicians having negative attitudes towards homosexuality,most are able to accept homosexuality.With better education in sexual orientation in the medical educational curriculum,the increase in knowledge will lead to better care for people with homosexuality.展开更多
This text combines authors' visits and examinations on the spot of Silicon Valley of U.S.A. and Park of Singapore, after analyzing the Park development experience of U.S.A. and Singapore, elucidates "three culture e...This text combines authors' visits and examinations on the spot of Silicon Valley of U.S.A. and Park of Singapore, after analyzing the Park development experience of U.S.A. and Singapore, elucidates "three culture effects" of Park development in terms of cultural system emphatically, then proposes some suggestions of cultural innovation in the Park of China.展开更多
"China-Singapore Tianjin Eco-city National Green Development Demonstration Execution Plan"has been officially approved to make it the first national green development demonstration area approved by State Cou..."China-Singapore Tianjin Eco-city National Green Development Demonstration Execution Plan"has been officially approved to make it the first national green development demonstration area approved by State Council,said Xie Zhenhua,vice director of National Development and Reform Commission recently.He said that the green economic development has become world trend,but for China,there are no experiences in展开更多
The 70-sq km Suzhou Industrial Park is situated in the eastern part of Suzhou city, with Donghuan road in the west, Luojiang in the north, Qiupu in the east and Huangtiantang in the south. It has a population of 620,0...The 70-sq km Suzhou Industrial Park is situated in the eastern part of Suzhou city, with Donghuan road in the west, Luojiang in the north, Qiupu in the east and Huangtiantang in the south. It has a population of 620,000 and the project covering three phases is to be finished in 15 years. Plans for the first phase of work on the opening of the展开更多
文摘On April 12,the National Youth Council of Singapore and the All-China Youth Federation jointly hosted the Second China-Singapore Youth Development Forum in Singapore.Themed"Youth Leadership and Sustainable Development",this forum was one of the major events of the China-Singapore Youth Leaders Exchange Camp.Ye Cong,Vice-Chairman of the All-China Youth Federation,and David Chua,Executive President of the National Youth Council of Singapore,attended the forum and delivered a speech respectively.Zhu Jing,Minister Counselor of the Chinese Embassy in Singapore,and nearly 100 Chinese and Singaporean youth representatives from various fields attended the forum.
文摘On April 27,the World Tai Chi Day-Tai Chi lecture and experience event,sponsored by China Cultural Center in Singapore and supported by the Bank of China Singapore Branch,ICBC Singapore Branch,Singapore International Wushu Cultural Centre,and Singapore Youth Culture&Arts Centre,was successfully held at China Cultural Center in Singapore.
文摘From September 8 to 9,Singapore's Foreign Minister Vivian Balakrishnan made an official visit to Beijing.It was the first visit by a Singaporean Foreign Minister to China since new Prime Minister Lawrence Wong succeeded Lee Hsien Loong.It was also the inaugural visit under an annual exchange mechanism between the ruling parties of both countries,which has been groundbreaking and exerted a positive influence on China-Singapore cooperation and regional development.
文摘The initial segment of this paper scrutinizes Descente’s promotional strategy for its training shoes in the Singapore market.Subsequently,the introduction section provides a brief overview on Descente’s products,emphasizing the age demographic of the product’s consumer base in Singapore,preferred purchasing channels and consumer behavior tendencies.This serves as a precursor to the main body of the article.Within the main body,the paper delves into an analysis of the primary marketing strategies,along with a detailed examination of specific operational implementation.Finally,the article concludes by summarizing key insights and evaluating their impact within the marketing domain.
基金This is a publication of the project ( No.71 )"Biodiversité de la faune etde la florede l’Asie du Sud- Est"of the Muséum national d’Histoire naturelleParis
文摘Three new species of Orthogonius Macleay (Coleoptera, Caraboidea) from Malaya Peninsula are described and illustrated in the present papr: O. solidicornis, sp. nov. (from Singapore), O. morvani, sp. nov. and O. thaicus, sp. nov. (from Thailand).
文摘Language planning plays a very important role in this world of globalization and multilingualism.With globalization,English has become a lingua franca for the whole world,whereas there seems to be an urgent need to preserve and protect local languages and cultures.How to linguistically achieve the aim of unity in diversity is of great significance to both linguists and soci?olinguists.This article intends to explore how to create a harmonious language ecology.From the perspective of language ecolo?gy,the article firstly discusses such issues as language planning and Language Ecology.It is then dedicated to the study of language planning and policy in Singapore by giving an account of the development of language policy in Singapore,how various languag?es coexist harmoniously,its bilingual policy,and illustrating how multilingualism and multiculturalism have been successfully prac?ticed in Singapore.Finally,some implications for language planning in China in dealing with the protection of minority languag?es,and solutions to intractable language problems in the execution of One Belt One Road policy are provided.
文摘A critical review is given on Singapore English. The historical introduction of the language provides readers a longitu dinal insight into the development of this special variety. Then, the language features of Colloquial Singapore English and Stan dard Singapore English are discussed, and a comparison of the use of Singapore and standard British English is made to show the differences in grammatical and lexical features of these two varieties of English.
文摘Objectives:To investigate the experience of newly graduated registered nurses(NGRNs)in Singapore following their initial 6-12 months of transition from nursing student to registered nurse.Methods:This mixed-methods study consisted of two phases.In the first phase,data were collected via the administration of the online survey to 30 NGRNs.The questionnaire contained 42 items of the fourpoint Likert scale survey.In the second phase,a focus group interview was conducted with 5 NGRNs to gather complementary information regarding the major findings from the first phase.Results:The survey revealed despite most NGRNs(80%)in this study expressed overall satisfied with their transition,the item score was(2.97±0.61)out of 4,the majority(83.3%)also perceived their transition to professional practice being stressful,the item score was(3.07±0.74)out of 4.Three themes emerged from the interview,'personal transition experience','professional transition experience',and'organizational transition experience',which are entwined to construct overall NGRNs'transition experiences.Conclusions:This study reaffirms the theory-practice gap phenomenon.This signifies the need for closer collaboration between educational,healthcare industry and regulatory stakeholders to examine and address factors that influence their transition experience to better support them for workforce readiness.
文摘With continual population growth in the densely populated cities,e.g.,Singapore,traffic congestion is the main transportation problem.As such,Public Transport is deemed as the most sustainable mode of transport.However,pubic transport is often plagued with the First and Last Mile Problem(FLMP),reducing its appeal especially in the densely populated city areas.The FLMP leads to a wide range of complications,in particular,human congestion in public transport.In this research,after a comprehensive discussion of FLMP problem in densely populated city areas,a case study in Singapore,i.e.,the Kent Ridge Campus of National University of Singapore(KRC-NUS),has been conducted based on the survey and spatio-temporal analyses.In addition to the investigation of FLMP status in the case study area,a new campus shuttle bus route from an alternative MRT station(Haw Par Villa Station)has also been proposed based on the Tabu Search to alleviate the human congestion and current FLMP status for KRC-NUS.This research not only has successfully addressed the FLMP in the case study area,but also can be a good reference for other areas in densely populated cities to help mitigate FLMPs.
文摘The Singapore seismic network and the seismicity of Singapore are briefly described, the four tremor events experienced by Singapore are discussed and the ground responses of different stations are compared. The tremor incident standing operation procedure is also presented.
文摘Burgeoning population and rapid urbanisation have contributed to two challenges facing cities today:food security and an increasing carbon footprint due to food imports.This paper examines the viability of rooftop farming in urban centres in Asia.A context-specific exploration—sited in Singapore—looks at the challenges of building integrated agriculture.Findings suggest that Singapore’s public housing estates are suitable for rooftop farming.Implemented nationwide,such a scheme could result in a 700%increase in domestic vegetable production,satisfying domestic demand by 35.5%.Reducing food imports would also decrease Singapore’s carbon footprint by 9,052 tonnes of emissions annually.
文摘Background:Varicella outbreaks occur frequently in closed environments such as those of militaries.This paper compares the economic outcomes of varicella vaccination in enlisted servicemen without prior reported varicella infection or vaccination.Methods:We analyzed the economic outcomes of a varicella vaccination program on all enlisted servicemen without prior reported varicella infection or vaccination in the Singapore Armed Forces(SAF) between December 11,2010–December 20,2013,compared with the previous program of varicella vaccination only for selected personnel between December 1,2007–December 10,2010.Results:In the at-risk population of all active SAF servicemen,the program of varicella vaccination for all servicemen without prior reported varicella infection or vaccination upon enlistment would save 72.0 work days per 1000(95% CI:61.2-82.9),valued at SG$6,544 per 1000(95% CI:6,524-6,564),i.e.,costing SG$91.5 per work day saved(95% CI:78.7-107.3).This also results in a reduction of 2.7 varicella cases per 1000 and 5.43 outbreaks per 10000,or a total savings of SG$1,695 per 1000(95% CI:–2,730-6,834),taking into account the cost of work days lost over a three-year period,compared with the previous regime of vaccinations only for selected individuals.Conclusion:The varicella vaccination strategy targeting all enlisted servicemen without prior reported varicella infection or vaccination is able to prevent varicella infections and outbreaks,thus reducing absenteeism and days lost.
文摘Following the success of the maiden World Refracto-ry Congress 2002, Worldrefractories Pte Ltd is pleased toannounce their next major global event-World RefractoryCongress 2004 which will bring forth discussions on issuesrelating to business, commercial and the latest technologi-cal developments in the refractory and allied industries
文摘BACKGROUND Invasive lobular carcinomas(ILC)form 5%-10%of breast cancer and rarely show overexpression of human epidermal growth factor receptor 2(HER2).AIM To describe the prevalence and prognostic factors of HER2 positive(HER2+)ILC in an Asian population.METHODS A retrospective review of patients with ILC seen between January 1985 and March 2018 at various SingHealth medical institutions was conducted.Demographic and clinical data were collected from medical records.We examined clinicopathological characteristics and survival in relation to HER2 status.RESULTS A total of 864 patients were included.Prevalence of HER2 positivity was 10.1%(87 patients).Compared with HER2 negative(HER2-)ILC,HER2+ILC was associated with a higher proportion of estrogen receptor negative(24.4%vs 5.9%,P<0.001),progesterone receptor negative(PR-)(40.2%vs 24%,P=0.002)and grade 3 tumours(Grade 3,29.0%vs 10.2%,P<0.001).Overall survival rate was poorer in patients with HER2+compared to HER2-ILC(56.7%vs 72.9%alive at 10 years;hazard ratio 1.87,95%confidence interval:1.21-2.90,P=0.004).Based on multivariate analysis,negative prognostic factors for overall survival included HER2 positivity,PR negativity,older age,Indian ethnicity and higher tumour stage.CONCLUSION Prevalence of HER2+ILC was 10.1%.HER2+ILC was more likely to have poorer prognostic features such as estrogen receptor negative,PR-and higher tumour grade,and have a poorer survival.
文摘Aims:This study aim to gain insights into attitudes,acceptance and knowledge levels among family physicians toward homosexual people,which are important as they may affect care among this at-risk group.Methods:An anonymized self-administered questionnaire in English was posted with the assistance of the College of Family Physicians Singapore in February 2015 to its 1529 members with self-addressed,pre-stamped envelopes for replies.The questionnaire included demographic questions such as age group,gender,religion,ethnicity,marital status and place of practice.Questions and scales that measured attitude,acceptance,knowledge and perception of colleagues who are homosexual were also included in the questionnaire.Results:451 responses(29.5%)were obtained,of which 441 were valid(28.84%).About 52.8%of participants were found to have negative,8.9%neutral and 38.3%positive attitudes toward homosexuality.Most(75.6%)were accepting of homosexuals,with 9.3%neutral and 15.1%not accepting.Knowledge levels were poor,with a mean score of 6.9 out of a maximum of 13.A strong correlation was found between the attitudes towards lesbians and gay men(ATLG)and acceptance of homosexuals scales(r=0.69,P<0.001),with moderate correlations between acceptance and knowledge(r=0.54,P<0.001)and ATLG and Knowledge(r=0.54,P<0.001).Conclusion:Despite majority of family physicians having negative attitudes towards homosexuality,most are able to accept homosexuality.With better education in sexual orientation in the medical educational curriculum,the increase in knowledge will lead to better care for people with homosexuality.
文摘This text combines authors' visits and examinations on the spot of Silicon Valley of U.S.A. and Park of Singapore, after analyzing the Park development experience of U.S.A. and Singapore, elucidates "three culture effects" of Park development in terms of cultural system emphatically, then proposes some suggestions of cultural innovation in the Park of China.
文摘"China-Singapore Tianjin Eco-city National Green Development Demonstration Execution Plan"has been officially approved to make it the first national green development demonstration area approved by State Council,said Xie Zhenhua,vice director of National Development and Reform Commission recently.He said that the green economic development has become world trend,but for China,there are no experiences in
文摘The 70-sq km Suzhou Industrial Park is situated in the eastern part of Suzhou city, with Donghuan road in the west, Luojiang in the north, Qiupu in the east and Huangtiantang in the south. It has a population of 620,000 and the project covering three phases is to be finished in 15 years. Plans for the first phase of work on the opening of the