In single-pixel imaging or computational ghost imaging,the measurement matrix has a great impact on the performance of the imaging system,because it involves modulation of the optical signal and image reconstruction.T...In single-pixel imaging or computational ghost imaging,the measurement matrix has a great impact on the performance of the imaging system,because it involves modulation of the optical signal and image reconstruction.The measurement matrix reported in the existing literatures is first binarized and then loaded onto the digital micro-mirror device(DMD)for optical modulation,that is,each pixel can only be modulated into on-off states.In this paper,we propose a digital grayscale modulation method for more efficient compressive sampling.On the basis of this,we demonstrate a single photon compressive imaging system.A control and counting circuit,based on field-programmable gate array(FPGA),is developed to control DMD to conduct digital grayscale modulation and count single-photon pulse output from the photomultiplier tube(PMT)simultaneously.The experimental results show that the imaging reconstruction quality can be improved by increasing the sparsity ratio properly and compressive sampling ratio(SR)of these gray-scale matrices.However,when the compressive SR and sparsity ratio are increased appropriately to a certain value,the reconstruction quality is usually saturated,and the imaging reconstruction quality of the digital grayscale modulation is better than that of binary modulation.展开更多
Purpose To develop a multi-radionuclide imaging system with a flexible and compact structure that has a potential for breast and other applications,and to evaluate its performances under both positron emission tomogra...Purpose To develop a multi-radionuclide imaging system with a flexible and compact structure that has a potential for breast and other applications,and to evaluate its performances under both positron emission tomography and single photon emission imaging conditions.Methods The plane detector was composed of 5×6 blocks with an effective detection area of 168.6 mm×202.4 mm.Each block consisted of a 16×16 LYSO array.The pixel size is 1.9 mm×1.9 mm×15 mm.An 8×8 silicon photomultiplier(SiPM)array with SensL’s C-30035 sensors was coupled to the LYSO array,separated by a 1.5-mm-thick glass.To minimize the influence of temperature on the detector,the active part of the front-end electronics was kept away from SiPMs.Self-designed data acquisition system and reconstruction software were utilized to evaluate the performances of the whole system.Results All the blocks had excellent pixels identification.An average energy resolution of 11.39%for 511 keV and 21.37%for 140 keV was obtained.In the PET mode,the best spatial resolution was better than 2 mm and the system sensitivity reached up to 11.05%at 60 mm distance.In the single photon emission imaging mode,a spatial resolution better than 3 mm was obtained.Conclusion The results indicated that the system has a good overall performance and can be used in breast imaging and other general PET applications.It also has the potential to be used for single photon emission imaging.In pursuit of a better spatial resolution of cross-plane,PSF and DOI technology will be developed in the next work.For specific applications,further improvement of the detector system such as performance evaluation with phantoms will be carried out.展开更多
基金This work was supported in part by the National Natural Science Foundation of China(Grants Nos.61865010 and 61565012)in part by the China Postdoctoral Science Foundation(Grant No.2015T80691)+1 种基金in part by the Science and Technology Plan Project of Jiangxi Province(Grant No.20151BBE50092)in part by the Funding Scheme to Outstanding Young Talents of Jiangxi Province(Grant No.20171BCB23007).
文摘In single-pixel imaging or computational ghost imaging,the measurement matrix has a great impact on the performance of the imaging system,because it involves modulation of the optical signal and image reconstruction.The measurement matrix reported in the existing literatures is first binarized and then loaded onto the digital micro-mirror device(DMD)for optical modulation,that is,each pixel can only be modulated into on-off states.In this paper,we propose a digital grayscale modulation method for more efficient compressive sampling.On the basis of this,we demonstrate a single photon compressive imaging system.A control and counting circuit,based on field-programmable gate array(FPGA),is developed to control DMD to conduct digital grayscale modulation and count single-photon pulse output from the photomultiplier tube(PMT)simultaneously.The experimental results show that the imaging reconstruction quality can be improved by increasing the sparsity ratio properly and compressive sampling ratio(SR)of these gray-scale matrices.However,when the compressive SR and sparsity ratio are increased appropriately to a certain value,the reconstruction quality is usually saturated,and the imaging reconstruction quality of the digital grayscale modulation is better than that of binary modulation.
基金the National NaturalScience Foundation of China(Grant Nos.11475206,11675191,and11805215).
文摘Purpose To develop a multi-radionuclide imaging system with a flexible and compact structure that has a potential for breast and other applications,and to evaluate its performances under both positron emission tomography and single photon emission imaging conditions.Methods The plane detector was composed of 5×6 blocks with an effective detection area of 168.6 mm×202.4 mm.Each block consisted of a 16×16 LYSO array.The pixel size is 1.9 mm×1.9 mm×15 mm.An 8×8 silicon photomultiplier(SiPM)array with SensL’s C-30035 sensors was coupled to the LYSO array,separated by a 1.5-mm-thick glass.To minimize the influence of temperature on the detector,the active part of the front-end electronics was kept away from SiPMs.Self-designed data acquisition system and reconstruction software were utilized to evaluate the performances of the whole system.Results All the blocks had excellent pixels identification.An average energy resolution of 11.39%for 511 keV and 21.37%for 140 keV was obtained.In the PET mode,the best spatial resolution was better than 2 mm and the system sensitivity reached up to 11.05%at 60 mm distance.In the single photon emission imaging mode,a spatial resolution better than 3 mm was obtained.Conclusion The results indicated that the system has a good overall performance and can be used in breast imaging and other general PET applications.It also has the potential to be used for single photon emission imaging.In pursuit of a better spatial resolution of cross-plane,PSF and DOI technology will be developed in the next work.For specific applications,further improvement of the detector system such as performance evaluation with phantoms will be carried out.
