Background: Acute Kidney Injury (AKI) stands as a prominent postoperative complication in on-pump cardiac surgery, with repercussions on morbidity, mortality, and hospitalization duration. Current diagnostic criteria ...Background: Acute Kidney Injury (AKI) stands as a prominent postoperative complication in on-pump cardiac surgery, with repercussions on morbidity, mortality, and hospitalization duration. Current diagnostic criteria relying on serum creatinine levels exhibit a delayed identification of AKI, prompting an exploration of alternative biomarkers. Aims and Objectives: This study is designed to overcome diagnostic constraints and explore the viability of serum Cystatin C as an early predictor of Acute Kidney Injury (AKI) in individuals undergoing on-pump cardiac surgery. The investigation aims to establish the relationship between serum Cystatin C levels and the onset of AKI in patients subjected to on-pump cardiac surgery. Primary objectives involve the assessment of the diagnostic effectiveness of serum Cystatin C, its comparison with serum creatinine, and the exploration of its potential for the early identification and treatment of AKI. Methodology: Conducted as a single-center study at the cardiac surgery department of BSMMU in Bangladesh from September 2020 to August 2022, a comparative cross-sectional analysis involved 31 participants categorized into No AKI and AKI groups based on Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Data collection encompassed preoperative, post-CBP (cardiopulmonary bypass) conclusion at 2 hours, postoperative day 1, and postoperative day 2 intervals. Statistical analyses included Chi-squared tests, independent Student’s t-tests, and one-sample t-tests. Significance was set at P Results: The study revealed no significant differences in baseline characteristics between the No AKI and AKI groups, except for CPB time and cross-clamp time. Serum Cystatin C levels in the AKI group exhibited statistical significance at various time points, highlighting its potential as an early detector. Conversely, Serum Creatinine levels in the AKI group showed no statistical significance. The Receiver Operating Characteristic (ROC) curve analysis further supported the efficacy of serum Cystatin C, with an Area under the ROC Curve of 0.864 and a cut-off value of 0.55 (p Conclusion: This study supports the superior utility of serum Cystatin C as an early detector of AKI in on-pump cardiac surgery patients compared to serum creatinine. Its ability to identify AKI several hours earlier may contribute to reduced morbidity, mortality, and healthcare costs. The findings underscore the significance of exploring novel biomarkers for improved post-cardiac surgery renal function assessment.展开更多
The disc-seal single screw pump(DSSP)used in the field of high viscosity oily sludge transport has a huge advantage.However,there is no research on the pressurization characteristics of the DSSP at present,which makes...The disc-seal single screw pump(DSSP)used in the field of high viscosity oily sludge transport has a huge advantage.However,there is no research on the pressurization characteristics of the DSSP at present,which makes its application limited.In view of this,the pressurization process mathematical model of the DSSP was established based on the geometric model of the pump.By using this model,the pressurization characteristics of DSSP and the influence of working parameters on the pressurization process were studied combined with the principle of back-flow pressurization.Analysis results show that the instantaneous pressurization process could be realized mainly depending on the reflux pressurization from the outlet chamber to the pressurization chamber when the screw rotor rotating angle is located at-5°to+5°.The pressure in the pressurization chamber will increase with the increase of working parameters which include inlet pressure,outlet pressure,screw rotation velocity and dynamic viscosity of fluid medium in the area of flow-back pressurization.The screw rotation velocity and the viscosity of the conveying medium have significant effects on the peak pressure in the pressurization chamber,and the peak pressure in the pressurization chamber is proportional to the screw rotation velocity and the dynamic viscosity coefficient of the conveying medium.The proportional coefficient between the peak pressure and the screw rotation velocity is 6.29×10~4.The proportional coefficient between the peak pressure and the dynamic viscosity of the conveying medium is 6.28×10~6.展开更多
A compact, efficient and high-power laser diode （LD） single-end-pumped Nd：YVO4 laser with continuous-wave emission at 1342 nm is reported. With a single crystal single-end-pumped by fibre-coupled LD array, an outpu...A compact, efficient and high-power laser diode （LD） single-end-pumped Nd：YVO4 laser with continuous-wave emission at 1342 nm is reported. With a single crystal single-end-pumped by fibre-coupled LD array, an output power of 7.36W is obtained from the laser cavity of concave-convex shape, corresponding to an optical-to-optical efficiency of 32.8%. The laser is operated in TEM00 mode with small rms amplitude noise of 0.3%. The influences of the Nd concentration, transmissivity of the output mirror and the cavity length on the output power have been studied experimentally.展开更多
The sub-Doppler absorption laser spectroscopy at 728nm transition from the 5D5/2 state to the 6F state of cesium with linewidth near 10 MHz is first experimentally performed with indirect pumping from the ground state...The sub-Doppler absorption laser spectroscopy at 728nm transition from the 5D5/2 state to the 6F state of cesium with linewidth near 10 MHz is first experimentally performed with indirect pumping from the ground state 6S1/2 to the state 7P3/2 by a 455.5nm diode laser. Using a 455.5nm diode laser as an indirect pump laser, several excited states will be populated due to spontaneous decay from the 7P state. We first implement the sub-Doppler absorption laser spectroscopy at 728nm from the 5D5/2 state to the 6F state when Cs atoms within thermal glass cell decay to the 5D5/2 state. Due to velocity transfer effect, the hyperfine structure of 5D5/2 shows a mixed and complicated pattern but very e/ear structure when the 455.5nm pumping laser is counter-propagating （or co-propagating） with the 728nm probing laser.展开更多
On the basis of practical projects in Chongqing,the thermal performance of heat exchangers (single U-tube type and double U-tube type) of the ground-source heat pump (GSHP) system in the hot summer was obtained and an...On the basis of practical projects in Chongqing,the thermal performance of heat exchangers (single U-tube type and double U-tube type) of the ground-source heat pump (GSHP) system in the hot summer was obtained and analyzed. The data obtained from test could match with the result deduced from theoretical calculation. From the test results,the cooling capacity of double U-tube is 1.6 times that of single U-tube. Taking cost per depth per watt Clq as the evaluation standard,Clq of single U-tube is 4.69 RMB$/W,and Clq of double U-tube is 3.14 RMB$/W. The double U-tube heat exchangers usage should be prioritized.展开更多
Current research on the operational reliability of centrifugal pumps has mainly focused on hydrodynamic instability. However, the interaction between the fluid and structure has not been sufficiently considered; this ...Current research on the operational reliability of centrifugal pumps has mainly focused on hydrodynamic instability. However, the interaction between the fluid and structure has not been sufficiently considered; this interaction can cause vibration and dynamic stress, which can affect the reliability. In this study, the dynamic stresses in a single-blade centrifugal pump impeller are analysed under different operating conditions; the two-way coupling method is used to calculate the fluid-structure interaction. Three-dimensional unsteady Reynolds-averaged Navier-Stokes equations are solved with the SST k-o9 turbulence model for the fluid in the whole flow passage, while transient structure dynamic analysis is used with the finite element method for the structure side. The dynamic stresses in the rotor system are computed according to the fourth strength theory. The stress results show that the highest stress is near the loose bearing and that the equivalent stress increases with the flow rate because the dynamic stresses are closely related to the pressure load. The stress distributions on the blade pressure side, suction side, leading edge, and trailing edge are each analysed for different flow rates; the highest stress distribution is found on the pressure side. On the blade pressure side, a relatively large stress is found near the trailing edge and hub side. Based on these results, a stress distribution prediction method is proposed for centrifugal pumps, which considers the interaction between the fluid and structuxe. The method can be used to check the dynamic stress at different flow rates when optimising the pump design to increase the pump reliability.展开更多
Theoretical and experimental analysis of a new refrigerant mixture BY-3 was conducted based on a single-stage vapor compression refrigeration system. The water-water heat pump system used BY-3 to produce hot water whe...Theoretical and experimental analysis of a new refrigerant mixture BY-3 was conducted based on a single-stage vapor compression refrigeration system. The water-water heat pump system used BY-3 to produce hot water when the low temperature was 20 ℃. The following results were obtained: the highest temperature at the condenser outlet reached about 85 ℃; when the difference between the water temperatures at the condenser outlet and the evaporator inlet was less than 40 ℃, the coefficient of performance (COP) was larger than 4; when the difference reached 55 ℃, the COP still kept 3; the discharge temperature of BY-3 was lower than 100 ℃, and the refrigerant vapor pressure kept lower than 1.8 MPa. When the water temperature at the condenser outlet reached over 85 ℃, nearly a 5 ℃ superheating temperature was maintained.展开更多
文摘Background: Acute Kidney Injury (AKI) stands as a prominent postoperative complication in on-pump cardiac surgery, with repercussions on morbidity, mortality, and hospitalization duration. Current diagnostic criteria relying on serum creatinine levels exhibit a delayed identification of AKI, prompting an exploration of alternative biomarkers. Aims and Objectives: This study is designed to overcome diagnostic constraints and explore the viability of serum Cystatin C as an early predictor of Acute Kidney Injury (AKI) in individuals undergoing on-pump cardiac surgery. The investigation aims to establish the relationship between serum Cystatin C levels and the onset of AKI in patients subjected to on-pump cardiac surgery. Primary objectives involve the assessment of the diagnostic effectiveness of serum Cystatin C, its comparison with serum creatinine, and the exploration of its potential for the early identification and treatment of AKI. Methodology: Conducted as a single-center study at the cardiac surgery department of BSMMU in Bangladesh from September 2020 to August 2022, a comparative cross-sectional analysis involved 31 participants categorized into No AKI and AKI groups based on Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Data collection encompassed preoperative, post-CBP (cardiopulmonary bypass) conclusion at 2 hours, postoperative day 1, and postoperative day 2 intervals. Statistical analyses included Chi-squared tests, independent Student’s t-tests, and one-sample t-tests. Significance was set at P Results: The study revealed no significant differences in baseline characteristics between the No AKI and AKI groups, except for CPB time and cross-clamp time. Serum Cystatin C levels in the AKI group exhibited statistical significance at various time points, highlighting its potential as an early detector. Conversely, Serum Creatinine levels in the AKI group showed no statistical significance. The Receiver Operating Characteristic (ROC) curve analysis further supported the efficacy of serum Cystatin C, with an Area under the ROC Curve of 0.864 and a cut-off value of 0.55 (p Conclusion: This study supports the superior utility of serum Cystatin C as an early detector of AKI in on-pump cardiac surgery patients compared to serum creatinine. Its ability to identify AKI several hours earlier may contribute to reduced morbidity, mortality, and healthcare costs. The findings underscore the significance of exploring novel biomarkers for improved post-cardiac surgery renal function assessment.
基金supported by National Key R&D Program of China[NO.2020YFB2010002]National Natural Science Foundation of China[NO.51706247,NO.51975585]the Fundamental Research Funds for the Central Universities and the Opening Fund of National Engineering Laboratory of Offshore Geophysical and Exploration Equipment[NO.20CX02312A]
文摘The disc-seal single screw pump(DSSP)used in the field of high viscosity oily sludge transport has a huge advantage.However,there is no research on the pressurization characteristics of the DSSP at present,which makes its application limited.In view of this,the pressurization process mathematical model of the DSSP was established based on the geometric model of the pump.By using this model,the pressurization characteristics of DSSP and the influence of working parameters on the pressurization process were studied combined with the principle of back-flow pressurization.Analysis results show that the instantaneous pressurization process could be realized mainly depending on the reflux pressurization from the outlet chamber to the pressurization chamber when the screw rotor rotating angle is located at-5°to+5°.The pressure in the pressurization chamber will increase with the increase of working parameters which include inlet pressure,outlet pressure,screw rotation velocity and dynamic viscosity of fluid medium in the area of flow-back pressurization.The screw rotation velocity and the viscosity of the conveying medium have significant effects on the peak pressure in the pressurization chamber,and the peak pressure in the pressurization chamber is proportional to the screw rotation velocity and the dynamic viscosity coefficient of the conveying medium.The proportional coefficient between the peak pressure and the screw rotation velocity is 6.29×10~4.The proportional coefficient between the peak pressure and the dynamic viscosity of the conveying medium is 6.28×10~6.
文摘A compact, efficient and high-power laser diode （LD） single-end-pumped Nd：YVO4 laser with continuous-wave emission at 1342 nm is reported. With a single crystal single-end-pumped by fibre-coupled LD array, an output power of 7.36W is obtained from the laser cavity of concave-convex shape, corresponding to an optical-to-optical efficiency of 32.8%. The laser is operated in TEM00 mode with small rms amplitude noise of 0.3%. The influences of the Nd concentration, transmissivity of the output mirror and the cavity length on the output power have been studied experimentally.
基金Supported by the National Natural Science Foundation of China under Grant No 91436210
文摘The sub-Doppler absorption laser spectroscopy at 728nm transition from the 5D5/2 state to the 6F state of cesium with linewidth near 10 MHz is first experimentally performed with indirect pumping from the ground state 6S1/2 to the state 7P3/2 by a 455.5nm diode laser. Using a 455.5nm diode laser as an indirect pump laser, several excited states will be populated due to spontaneous decay from the 7P state. We first implement the sub-Doppler absorption laser spectroscopy at 728nm from the 5D5/2 state to the 6F state when Cs atoms within thermal glass cell decay to the 5D5/2 state. Due to velocity transfer effect, the hyperfine structure of 5D5/2 shows a mixed and complicated pattern but very e/ear structure when the 455.5nm pumping laser is counter-propagating （or co-propagating） with the 728nm probing laser.
基金The project supported by National Natural Science Foundation of China under Grant No. 10275025 and the Education Foundation of Hebei Province under Grant No. 2004D006.
文摘On the basis of practical projects in Chongqing,the thermal performance of heat exchangers (single U-tube type and double U-tube type) of the ground-source heat pump (GSHP) system in the hot summer was obtained and analyzed. The data obtained from test could match with the result deduced from theoretical calculation. From the test results,the cooling capacity of double U-tube is 1.6 times that of single U-tube. Taking cost per depth per watt Clq as the evaluation standard,Clq of single U-tube is 4.69 RMB$/W,and Clq of double U-tube is 3.14 RMB$/W. The double U-tube heat exchangers usage should be prioritized.
基金supported by National Natural Science Foundation of China(Grant Nos.51239005,51009072)National Science & Technology Pillar Program of China(Grant No.2011BAF14B04)
文摘Current research on the operational reliability of centrifugal pumps has mainly focused on hydrodynamic instability. However, the interaction between the fluid and structure has not been sufficiently considered; this interaction can cause vibration and dynamic stress, which can affect the reliability. In this study, the dynamic stresses in a single-blade centrifugal pump impeller are analysed under different operating conditions; the two-way coupling method is used to calculate the fluid-structure interaction. Three-dimensional unsteady Reynolds-averaged Navier-Stokes equations are solved with the SST k-o9 turbulence model for the fluid in the whole flow passage, while transient structure dynamic analysis is used with the finite element method for the structure side. The dynamic stresses in the rotor system are computed according to the fourth strength theory. The stress results show that the highest stress is near the loose bearing and that the equivalent stress increases with the flow rate because the dynamic stresses are closely related to the pressure load. The stress distributions on the blade pressure side, suction side, leading edge, and trailing edge are each analysed for different flow rates; the highest stress distribution is found on the pressure side. On the blade pressure side, a relatively large stress is found near the trailing edge and hub side. Based on these results, a stress distribution prediction method is proposed for centrifugal pumps, which considers the interaction between the fluid and structuxe. The method can be used to check the dynamic stress at different flow rates when optimising the pump design to increase the pump reliability.
基金Supported by Major State Basic Research Development Program of China ("973" Program, No. 2009CB219907)the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT0936)
文摘Theoretical and experimental analysis of a new refrigerant mixture BY-3 was conducted based on a single-stage vapor compression refrigeration system. The water-water heat pump system used BY-3 to produce hot water when the low temperature was 20 ℃. The following results were obtained: the highest temperature at the condenser outlet reached about 85 ℃; when the difference between the water temperatures at the condenser outlet and the evaporator inlet was less than 40 ℃, the coefficient of performance (COP) was larger than 4; when the difference reached 55 ℃, the COP still kept 3; the discharge temperature of BY-3 was lower than 100 ℃, and the refrigerant vapor pressure kept lower than 1.8 MPa. When the water temperature at the condenser outlet reached over 85 ℃, nearly a 5 ℃ superheating temperature was maintained.
