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CFD simulation of single-phase flow in flotation cells:Effect of impeller blade shape,clearance,and Reynolds number 被引量:5
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作者 Manjunath Basavarajappa Sanja Miskovic 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2019年第5期657-669,共13页
A series of numerical simulations of turbulent single-phase flows are performed to understand the flow and mixing characteristics in a laboratory scale flotation tank.Four impeller blade shapes covering a wide range o... A series of numerical simulations of turbulent single-phase flows are performed to understand the flow and mixing characteristics in a laboratory scale flotation tank.Four impeller blade shapes covering a wide range of surface areas and lip lengths are considered to highlight and contrast the flow behavior predicted in the impeller stream.The mean flow close to the impeller is fully characterized by considering velocity components along the axial direction at different radial locations.Normalized results suggest the development of a comparatively stronger axial velocity component for a blade design with the smallest lip length,called big-tip impeller here.Normalized turbulent kinetic energy profiles close to the impeller reveal the existence of an asymmetric trailing vortex pair.The highest turbulence kinetic energy dissipation rates are observed close to the impeller blades and stator walls where the radial jet strikes the stator walls periodically.Furthermore,liquid phase mixing in the flotation cell is studied using transient scalar tracing simulations providing mixing time data.Finally,pumping capacity and efficiency of different impeller designs are calculated based on which the impeller blade design with a rectangular blade design is found to perform most efficiently. 展开更多
关键词 FLOTATION IMPELLER BLADE design TURBULENT flow Mixing PUMPING efficiency
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SENSITIVITY COEFFICIENTS OF SINGLE-PHASE FLOW IN LOW-PERMEABILITY HETEROGENEOUS RESERVOIRS
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作者 程时清 张盛宗 +1 位作者 黄延章 朱维耀 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2002年第6期712-720,共9页
Theoretical equations for computing sensitivity coefficients of wellbore pressures to estimate the reservoir parameters in low-permeability reservoirs conditioning to non-Darcy flow data at low velocity were obtained.... Theoretical equations for computing sensitivity coefficients of wellbore pressures to estimate the reservoir parameters in low-permeability reservoirs conditioning to non-Darcy flow data at low velocity were obtained. It is shown by a lot of numerical calculations that the wellbore pressures are much more sensitive to permeability very near the well than to permeability a few gridblocks away from the well. When an initial pressure gradient existent sensitivity coefficients in the region are closer to the active well than to the observation well. Sensitivity coefficients of observation well at the line between the active well and the observation well are influenced greatly by the initial pressure gradient. 展开更多
关键词 non-Darcy flow through porous media PERMEABILITY POROSITY sensitivity coefficient inverse problem low-permeability reservoir
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Turbulence Modelling of a Single-Phase Flow Cyclone Gasifier
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作者 Pantea Hadi Jafari J.Gunnar I.Hellstrom B.Rikard Gebart 《Engineering(科研)》 2017年第9期779-799,共21页
The current work aims to make a foundation for an engineering design of a cyclone gasifier to be able not only to predict its flow field with a suitable accuracy but also to investigate a large number of design altern... The current work aims to make a foundation for an engineering design of a cyclone gasifier to be able not only to predict its flow field with a suitable accuracy but also to investigate a large number of design alternatives with limited computer resources. A good single-phase flow model that can form the basis in an Euler-Lagrange model for multi-phase flow is also necessary?for modelling the reacting flow inside a cyclone gasifier. The present paper provides an objective comparison between several popular turbulence modelling options including standard k-ε and SST with curvature corrections, SSG-RSM and LES Smagorinsky models, for the single-phase flow inside cyclone separators/gasifiers that can serve as a guide for further work on the reacting multi-phase flow inside cyclone gasifiers and similar devices. A detailed comparison between the models and experimental data for the mean velocity and fluctuating parts of the velocity profiles are presented. Furthermore, the capabilities of the turbulence models to capture the physical phenomena present in a cyclone gasifier that?affects the design process are investigated. 展开更多
关键词 Cyclone Gasifier Turbulence Modelling Swirling flow Pattern Secondary flow
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CHARACTERISTICS OF PRESSURE DROP AND CORRELATION OF FRICTION FACTORS FOR SINGLE-PHASE FLOW IN ROLLING HORIZONTAL PIPE 被引量:18
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作者 ZHANG Jin-hong YAN Chang-qi GAO Pu-zhen 《Journal of Hydrodynamics》 SCIE EI CSCD 2009年第5期614-621,共8页
Gas-liquid two-phase flow occurs increasingly in some dynamic devices operating in the oceanic condition. The relative data are limited with respect to flow characteristics, so the present study is to investigate syst... Gas-liquid two-phase flow occurs increasingly in some dynamic devices operating in the oceanic condition. The relative data are limited with respect to flow characteristics, so the present study is to investigate systematically single-phase pressure drop, and to develop the theory for frictional factor under the roiling condition. Using deionized water as the test fluid, a series of experiments of single-phase flow were conducted in pipe with the inner diameter of 34.5 ram. The test section was horizontally settled on the rolling apparatus, and its regularity was similar to simple harmonic motion. It is found that the pressure drop during rolling motion fluctuate with the change of the rolling period and rolling angle, which is significantly different from fluid motion in a steady state. By the contrast between experiment results and stable-state theory values, existing correlations can not predict present frictional factor very well. Therefore, in the present article, the single-phase frictional factor is correlated with the Reynolds number for rolling motion, and its computated results agree well with experimental data. 展开更多
关键词 single-phase flow pressure drop friction factor horizontal pipe rolling motion
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ERRATUM TO “CHARACTERISTICS OF PRESSURE DROP AND CORRELATION OF FRICTION FACTORS FOR SINGLE-PHASE FLOW IN ROLLING HORIZONTAL PIPE”
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作者 ZHANG Jin-hong YAN Chang-qi GAO Pu-zhen 《Journal of Hydrodynamics》 SCIE EI CSCD 2009年第6期868-868,共1页
This is the erratum to the article [zhang Jin-hong, Yan Chang-qi, Gao Pu-zhen, Journal of Hydrodynamics, 2009, 21(5)]. The Fig.5 is corrected.
关键词 CHARACTERISTICS OF PRESSURE DROP AND CORRELATION OF FRICTION FACTORS FOR single-phase flow IN ROLLING HORIZONTAL PIPE ERRATUM TO
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4D-Flow MRI在肥厚型心肌病左室流出道血流评估中的价值探索
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作者 徐晶 陈秀玉 +3 位作者 尹刚 闫伟鹏 陆敏杰 赵世华 《磁共振成像》 CAS CSCD 北大核心 2024年第3期56-61,共6页
目的 探索四维血流(four-dimensional flow,4D-Flow)磁共振成像(magnetic resonance imaging,MRI)技术在左心室腔内应用的可行性。材料与方法 本研究为前瞻性、横断面研究,纳入2022年8月至2023年1月于我院接受心脏MRI检查的21例肥厚型... 目的 探索四维血流(four-dimensional flow,4D-Flow)磁共振成像(magnetic resonance imaging,MRI)技术在左心室腔内应用的可行性。材料与方法 本研究为前瞻性、横断面研究,纳入2022年8月至2023年1月于我院接受心脏MRI检查的21例肥厚型心肌病患者,采用3.0 T MRI扫描仪进行二维血流(tow-dimensional flow,2D-Flow)及4D-Flow成像,收集患者一周内进行的超声心动图检查结果。采用组内相关系数(inter-class correlation coefficient,ICC)、变异系数(coefficients of variation,COV)及Bland-Altman分析比较2D-Flow、4D-Flow评估左室流出道峰值流速的可重复性及一致性,并通过Pearson相关性分析探究二者与超声心动图测量结果的关系。结果 2D-Flow和4D-Flow观察者内/观察者间的ICC分别为0.999/0.999和0.995/0.992,COV分别为0.5%/0.5%和2.4%/2.6%。4D-Flow与超声心动图的测量结果呈中度相关,相关系数r值为0.574(P=0.006),但一致性较差,ICC为0.375(P=0.013)。2D-Flow与4D-Flow和超声心动图间无显著的一致性及相关性。结论 4D-Flow技术能够可视化心腔内血流模式,对左室流出道峰值流速的测量具有高度可重复性,且与超声心动图的测量结果具有显著的一致性。 展开更多
关键词 肥厚型心肌病 四维血流 二维血流 心脏磁共振 磁共振成像
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Dynamic behavior of coalbed methane flow along the annulus of single-phase production 被引量:3
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作者 Xinfu Liu Chunhua Liu Guoqiang Liu 《International Journal of Coal Science & Technology》 EI 2019年第4期547-555,共9页
Dynamic behavior of coalbed methane (CBM) flow will provide the theoretical basis to optimize production performance for a given well.A mathematical model is developed to simulate flowing pressures and pressure drops ... Dynamic behavior of coalbed methane (CBM) flow will provide the theoretical basis to optimize production performance for a given well.A mathematical model is developed to simulate flowing pressures and pressure drops of CBM column from well head to bottom hole.The measured parameters and independent variables of flow rates,flowing pressures and temperatures are involved in CBM producing process along the annulus.The developed relationships are validated against full-scale measured data in single-phase CBM wellbores.The proposed methodology can analyze the dynamic behavior in CBM reservoir and process of CBM flow with an overall accuracy of 2%.The calculating process of flowing pressures involves friction factor with variable Reynolds number and CBM temperature and compressibility factor with gravitational gradients.The results showed that the effect of flowing pressure on CBM column was more obvious than that on CBM and water column accompanied by an increase of dynamic water level.The ratios of flowing pressure on increment of CBM column to the whole column increased with the declined flow rates of water column.Bottom-hole pressure declined with the decreased flowing pressure of CBM column along the annulus.It will lead to the results of the increased pressure drop of CBM column and CBM flow rate in single-phase CBM wellbores. 展开更多
关键词 Dynamic CHARACTERISTIC single-phase CBM wellbore flowing pressure of CBM COLUMN flow rate of CBM COLUMN
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肝硬化患者4D flow MRI血流动力学参数与中医证型的相关性研究
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作者 胡勤勤 姜阳 +3 位作者 张玉龙 方玉 梁仁容 杨华 《中国中医急症》 2024年第6期982-985,989,共5页
目的探讨肝硬化患者4D flow MRI血流动力学参数与中医证型的相关性。方法将118例肝硬化患者依据中医辨证分为肝气郁结证、湿热蕴结证、肝肾阴虚证、脾肾阳虚证、瘀血阻络证5个证型,所有患者均行门静脉4D flow MRI检查,统计不同证型肝硬... 目的探讨肝硬化患者4D flow MRI血流动力学参数与中医证型的相关性。方法将118例肝硬化患者依据中医辨证分为肝气郁结证、湿热蕴结证、肝肾阴虚证、脾肾阳虚证、瘀血阻络证5个证型,所有患者均行门静脉4D flow MRI检查,统计不同证型肝硬化患者分布情况,观察门静脉系统(门静脉主干、脾静脉、肠系膜上静脉)的血流动力学参数,包括血流量、流速、壁剪切力等,比较不同证型患者门静脉血流动力学参数差异。结果肝硬化代偿期以肝气郁结证、湿热蕴结证为主,肝硬化失代偿期以脾肾阳虚、瘀血络阻证为主;A级以肝气郁结证、湿热蕴结证为主,B、C级以瘀血络阻证为主。瘀血络阻证肝硬化患者门静脉主干及脾静脉血流量明显高于肝气郁结证、湿热蕴结证患者(P<0.05);脾肾阳虚证门静脉主干血流量明显高于肝气郁结证肝硬化患者(P<0.05);瘀血络阻证肝硬化患者门静脉主干流速及剪切力较肝气郁结证和湿热蕴结证低。结论肝硬化患者中医辨证分型与门静脉血流动力学参数具有一定相关性,4D flow MRI可为肝硬化的中医辨证提供血流动力学参考。 展开更多
关键词 肝硬化 4D flow MRI 血流动力学 中医证型
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基于 Moldflow 的汽车中控台框架翘曲变形分析及优化
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作者 刘巨保 黄建军 +3 位作者 杨明 李峰 张亮 查翔 《塑料工业》 CAS CSCD 北大核心 2024年第3期83-88,共6页
以某汽车中控台框架为研究对象,测量试模样品发现其翘曲变形量超过了装配要求。通过Moldflow软件模拟了该塑件实际的注塑过程,翘曲变形量的模拟值与实测平均值的最大误差为5.98%,发现该塑件翘曲变形的主要因素为冷却不均和收缩不均。本... 以某汽车中控台框架为研究对象,测量试模样品发现其翘曲变形量超过了装配要求。通过Moldflow软件模拟了该塑件实际的注塑过程,翘曲变形量的模拟值与实测平均值的最大误差为5.98%,发现该塑件翘曲变形的主要因素为冷却不均和收缩不均。本文在原物料中添加质量分数为25%的玻璃纤维以及优化工艺参数后,翘曲变形量的模拟值与初始方案相比降低了86.22%。试模验证表明,优化后的翘曲变形量模拟值与实测平均值的最大误差为4.35%,证明了Moldflow软件模拟分析的准确性。试模后各检测点的最大翘曲变形量降到了1.6 mm以下,较优化之前降低了80%以上,为类似大型复杂注塑件的翘曲变形分析及优化提供了思路。 展开更多
关键词 注塑成型 中控台框架 翘曲变形 模流分析 玻璃纤维
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V Flow技术测量颈动脉壁面剪应力的一致性研究
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作者 加依达尔·沙亚哈提 周琛云 陈曼琳 《四川医学》 CAS 2024年第1期28-34,共7页
目的评价血流向量成像(V Flow)技术在测量健康成年人颈动脉壁面剪应力(WSS)中的一致性。方法于2021年2月至2021年3月招募健康成年志愿者20人,由2名不同年资的超声医师使用配备V Flow功能的Mindray Resona 7超声仪和3~9 MHz线阵探头进行... 目的评价血流向量成像(V Flow)技术在测量健康成年人颈动脉壁面剪应力(WSS)中的一致性。方法于2021年2月至2021年3月招募健康成年志愿者20人,由2名不同年资的超声医师使用配备V Flow功能的Mindray Resona 7超声仪和3~9 MHz线阵探头进行双侧颈动脉扫查,分别采集双侧颈总动脉远段、颈总动脉分叉至颈内动脉起始部两段动脉的动态V Flow图像,测量两侧颈总动脉远段的近心端、远心端、分叉处及颈内动脉起始部的前、后壁的WSS,使用组内相关系数(ICC)和Bland-Altman图评估组内一致性及组间一致性。结果双侧颈动脉前、后壁的4个不同节段之间WSS值差异均有统计学意义(P<0.05)。高年资超声医师2次测量结果的一致性结果显示,左侧颈总动脉远段的远心端一致性极好(ICC 0.779),右侧颈总动脉远段的近心端(ICC 0.605)、远心端(ICC 0.585)、颈内动脉起始部(ICC 0.457)、左侧颈总动脉分叉处(ICC 0.606)及颈内动脉起始部(ICC 0.702)一致性均较好;不同年资超声医师的测量结果显示,仅右侧颈总动脉分叉处(ICC 0.486)及左侧颈总动脉远段的远心端(ICC 0.576)一致性较好。结论V Flow技术可显示不同位点间颈动脉WSS之间的差异,其组内一致性较好,但在不同年资超声医师间存在一定的差异。 展开更多
关键词 颈动脉 动脉粥样硬化 壁面剪应力 V flow成像技术
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基于Moldflow软件对薄壁件某塑料喷嘴的注塑方案优化研究
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作者 袁志华 符烜赫 袁博 《机械工程师》 2024年第3期14-17,共4页
喷嘴注塑产品的质量和性能很大程度上由注塑方案和工艺参数所决定,不当的注塑方案和工艺参数会导致充填不足、熔接线过多、翘曲变形量大等问题。为了可以减少生产周期,节约生产成本,利用三维软件UG对喷嘴进行建模,基于模流分析软件Moldf... 喷嘴注塑产品的质量和性能很大程度上由注塑方案和工艺参数所决定,不当的注塑方案和工艺参数会导致充填不足、熔接线过多、翘曲变形量大等问题。为了可以减少生产周期,节约生产成本,利用三维软件UG对喷嘴进行建模,基于模流分析软件Moldflow软件对喷嘴注塑产品进行分析和优化,通过比较点浇口和侧浇口两种方案的分析结果,最终确定该产品点浇口的方案更好。并通过设计正交实验,得到优化后的工艺参数。 展开更多
关键词 喷嘴 MOLDflow 模流分析 浇口位置 正交优化
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Modified surface tension model for free surface flow with single-phase lattice Boltzmann method 被引量:1
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作者 严永华 杨帆 +1 位作者 钱忠东 钱跃竑 《Journal of Shanghai University(English Edition)》 CAS 2010年第2期145-149,共5页
A single-phase lattice Boltzmann model with modified surface tension is developed in this paper to solve the problem of high-density-ratio free surface flow.The computational efficiency and accuracy are both enhanced.... A single-phase lattice Boltzmann model with modified surface tension is developed in this paper to solve the problem of high-density-ratio free surface flow.The computational efficiency and accuracy are both enhanced.The restriction to the relaxation factor (which needs to be smaller than 1) is circumvented by the new surface tension algebra,due to its rational physical nature compared with the treatment of Xing,Buther and Yang in their paper (Comp.Mater.Sci.,2007,39(2):282-290).The proposed stable surface tension scheme is applied to simulate the free deformation of a square droplet with surface tension effect and the process of a droplet impinging on a liquid film.The numerical solution for free deformation of a droplet agrees well with thermodynamic principles,and also achieves high accuracy in comparison with Xing,et al.'s model.Three typical impinging modes are successfully obtained with the new scheme,and another particular mode found by Wang and Chen is also successfully simulated.The evolutions of liquid crown agree well with the power law related to time. 展开更多
关键词 surface tension lattice Boltzmann model (LBM) single-phase model high density ratio free surface DROPLET
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A quasi single-phase model for debris flows and its comparison with a two-phase model
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作者 XIA Chun-chen LI Ji +2 位作者 CAO Zhi-xian LIU Qing-quan HU Kai-heng 《Journal of Mountain Science》 SCIE CSCD 2018年第5期1071-1089,共19页
A depth-averaged quasi single-phase mixture model is proposed for debris flows over inclined bed slopes based on the shallow water hydrosediment-morphodynamic theory with multi grain sizes. The stresses due to fluctua... A depth-averaged quasi single-phase mixture model is proposed for debris flows over inclined bed slopes based on the shallow water hydrosediment-morphodynamic theory with multi grain sizes. The stresses due to fluctuations are incorporated based on analogy to turbulent flows, as estimated using the depth-averaged k-? turbulence model and a modification component. A fully conservative numerical algorithm, using wellbalanced slope limited centred scheme, is deployed to solve the governing equations. The present quasi single-phase model using four closure relationships for the bed shear stresses is evaluated against USGS experimental debris flow and compared with traditional quasi single-phase models and a recent physically enhanced two-phase model. It is found that the present quasi single-phase model performs much better than the traditional models, and is attractive in terms of computational cost while the two-phase model performs even better appreciably. 展开更多
关键词 DEBRIS flows QUASI single-phase mixturemodel Stresses DUE to FLUCTUATIONS Well-balanced
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基于MoldFlow太阳能储能系统下盖成型模拟及应用
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作者 周先保 胡清根 傅海勇 《模具制造》 2024年第2期36-38,共3页
以太阳能储能系统下盖模流分析为例,反复修改流道和浇口截面尺寸与长度以及主流道位置,确定流道尺寸。运用MoldFlow对设计好的流道进行充填分析,以使成型达到流动平衡,并进行冷却、翘曲分析,预测成型缺陷,提出解决措施,为模具设计提供... 以太阳能储能系统下盖模流分析为例,反复修改流道和浇口截面尺寸与长度以及主流道位置,确定流道尺寸。运用MoldFlow对设计好的流道进行充填分析,以使成型达到流动平衡,并进行冷却、翘曲分析,预测成型缺陷,提出解决措施,为模具设计提供浇注系统和冷却系统方案和注射成型工艺参数,并应用于模具设计和实际生产。 展开更多
关键词 太阳能储能系统下盖 流动平衡 成型缺陷
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A transient production prediction method for tight condensate gas wells with multiphase flow
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作者 BAI Wenpeng CHENG Shiqing +3 位作者 WANG Yang CAI Dingning GUO Xinyang GUO Qiao 《Petroleum Exploration and Development》 SCIE 2024年第1期172-179,共8页
Considering the phase behaviors in condensate gas reservoirs and the oil-gas two-phase linear flow and boundary-dominated flow in the reservoir,a method for predicting the relationship between oil saturation and press... Considering the phase behaviors in condensate gas reservoirs and the oil-gas two-phase linear flow and boundary-dominated flow in the reservoir,a method for predicting the relationship between oil saturation and pressure in the full-path of tight condensate gas well is proposed,and a model for predicting the transient production from tight condensate gas wells with multiphase flow is established.The research indicates that the relationship curve between condensate oil saturation and pressure is crucial for calculating the pseudo-pressure.In the early stage of production or in areas far from the wellbore with high reservoir pressure,the condensate oil saturation can be calculated using early-stage production dynamic data through material balance models.In the late stage of production or in areas close to the wellbore with low reservoir pressure,the condensate oil saturation can be calculated using the data of constant composition expansion test.In the middle stages of production or when reservoir pressure is at an intermediate level,the data obtained from the previous two stages can be interpolated to form a complete full-path relationship curve between oil saturation and pressure.Through simulation and field application,the new method is verified to be reliable and practical.It can be applied for prediction of middle-stage and late-stage production of tight condensate gas wells and assessment of single-well recoverable reserves. 展开更多
关键词 tight reservoir condensate gas multiphase flow phase behavior transient flow PSEUDO-PRESSURE production prediction
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Debris Fan Produced by Failure of Canyon-Blocking Pyroclastic Flows
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作者 Michael L. Cummings 《Journal of Water Resource and Protection》 CAS 2024年第5期328-360,共33页
Ash-rich pyroclastic flows from the cataclysmic eruption of Mount Mazama (~7700 yr. B. P.), Cascade volcanic arc, Oregon, entered and blocked the narrow, bedrock-lined canyon of the Williamson River approximately 35 t... Ash-rich pyroclastic flows from the cataclysmic eruption of Mount Mazama (~7700 yr. B. P.), Cascade volcanic arc, Oregon, entered and blocked the narrow, bedrock-lined canyon of the Williamson River approximately 35 to 44 km from the source volcano. The blockage impounded a body of water which then released producing four stratigraphic units in the downstream debris fan. The four stratigraphic units are a boulder core comprised of locally sourced bedrock boulders and three sand-rich units including a fine-grained sand unit, a sandy pumice gravel (±basalt/hydrovolcanic tuff) unit, and a pumice pebble-bearing, crystal-rich sand unit. Hand-drilled auger holes up to ~1.6 m deep were used to obtain samples of the sand-rich units. Units were delimited using surface and down-hole observations, composition and texture, estimated density, statistical parameters of grain size, and vertical and lateral distribution of properties. Overtopping followed by rapid incision into the ash-rich pyroclastic flows progressively cleared the canyon, but a bedrock knickpoint near the head of the canyon limited the volume of debris available for transport to about 0.04 km<sup>3</sup> to 0.08 km<sup>3</sup>. Co-deposition of bedrock boulders and lithic-rich sand was followed by rapid deposition with minimal reworking of remobilized pyroclastics. Continued draining of the impounded lake sent hyperconcentrated flows onto the debris fan depositing pumice-rich gravels that graded upward to crystal-rich sands. 展开更多
关键词 Outburst Flood Mount Mazama Debris Fan Canyon Blockage Pyroclastic flows
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Diagnostic performance of intravascular ultrasound-based fractional flow reserve in evaluating of intermediate left main stenosis
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作者 Yong-Gang SUI Cheng YANG +11 位作者 Chang-Dong GUAN Yan-Lu XU Na-Qiong WU Wei-Xian YANG Yong-Jian WU Ke-Fei DOU Yue-Jin YANG Shu-Bin QIAO Wei YU Bo XU Sheng-Xian TU Jie QIAN 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2024年第1期34-43,共10页
BACKGROUND The recently introduced ultrasonic flow ratio(UFR),is a novel fast computational method to derive fractional flow reserve(FFR)from intravascular ultrasound(IVUS)images.In the present study,we evaluate the d... BACKGROUND The recently introduced ultrasonic flow ratio(UFR),is a novel fast computational method to derive fractional flow reserve(FFR)from intravascular ultrasound(IVUS)images.In the present study,we evaluate the diagnostic performance of UFR in patients with intermediate left main(LM)stenosis.METHODS This is a prospective,single center study enrolling consecutive patients with presence of intermediated LM lesions(diameter stenosis of 30%-80%by visual estimation)underwent IVUS and FFR measurement.An independent core laboratory assessed offline UFR and IVUS-derived minimal lumen area(MLA)in a blinded fashion.RESULTS Both UFR and FFR were successfully achieved in 41 LM patients(mean age,62.0±9.9 years,46.3%diabetes).An acceptable correlation between UFR and FFR was identified(r=0.688,P<0.0001),with an absolute numerical difference of 0.03(standard difference:0.01).The area under the curve(AUC)in diagnosis of physiologically significant coronary stenosis for UFR was 0.94(95%CI:0.87-1.01),which was significantly higher than angiographic identified stenosis>50%(AUC=0.66,P<0.001)and numerically higher than IVUS-derived MLA(AUC=0.82;P=0.09).Patient level diagnostic accuracy,sensitivity and specificity for UFR to identify FFR≤0.80 was 82.9%(95%CI:70.2-95.7),93.1%(95%CI:82.2-100.0),58.3%(95%CI:26.3-90.4),respectively.CONCLUSION In patients with intermediate LM diseases,UFR was proved to be associated with acceptable correlation and high accuracy with pressure wire-based FFR as standard reference.The present study supports the use of UFR for functional evaluation of intermediate LM stenosis. 展开更多
关键词 STENOSIS flow FRACTIONAL
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A multichannel thermal bubble-actuated impedance flow cytometer with on-chip TIA based on CMOS-MEMS
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作者 Shengxun Cai Jianqing Nie +2 位作者 Kun Wang Yimin Guan Demeng Liu 《Journal of Semiconductors》 EI CAS CSCD 2024年第5期41-49,共9页
Electrochemical impedance spectroscopy(EIS)flow cytometry offers the advantages of speed,affordability,and portability in cell analysis and cytometry applications.However,the integration challenges of microfluidic and... Electrochemical impedance spectroscopy(EIS)flow cytometry offers the advantages of speed,affordability,and portability in cell analysis and cytometry applications.However,the integration challenges of microfluidic and EIS read-out circuits hinder the downsizing of cytometry devices.To address this,we developed a thermal-bubble-driven impedance flow cytometric application-specific integrated circuit(ASIC).The thermal-bubble micropump avoids external piping and equipment,enabling high-throughput designs.With a total of 36 cell counting channels,each measuring 884×220μm^(2),the chip significantly enhances the throughput of flow cytometers.Each cell counting channel incorporates a differential trans-impedance amplifier(TIA)to amplify weak biosensing signals.By eliminating the parasitic parameters created at the complementary metal-oxidesemiconductor transistor(CMOS)-micro-electromechanical systems(MEMS)interface,the counting accuracy can be increased.The on-chip TIA can adjust feedback resistance from 5 to 60 kΩto accommodate solutions with different impedances.The chip effectively classifies particles of varying sizes,demonstrated by the average peak voltages of 0.0529 and 0.4510 mV for 7 and 14μm polystyrene beads,respectively.Moreover,the counting accuracies of the chip for polystyrene beads and MSTO-211H cells are both greater than 97.6%.The chip exhibits potential for impedance flow cytometer at low cost,high-throughput,and miniaturization for the application of point-of-care diagnostics. 展开更多
关键词 EIS flow cytometry CMOS-MEMS thermal bubble LAB-ON-CHIP
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Numerical simulation on the multiphase flow and reoxidation of the molten steel in a two-strand tundish during ladle change
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作者 Jingcheng Wang Zhentong Liu +2 位作者 Wei Chen Hongliang Chen Lifeng Zhang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第7期1540-1553,共14页
A 3D mathematical model was proposed to investigate the molten steel–slag–air multiphase flow in a two-strand slab continuous casting(CC)tundish during ladle change.The study focused on the exposure of the molten st... A 3D mathematical model was proposed to investigate the molten steel–slag–air multiphase flow in a two-strand slab continuous casting(CC)tundish during ladle change.The study focused on the exposure of the molten steel and the subsequent reoxidation occurrence.The exposure of the molten steel was calculated using the coupled realizable k–εmodel and volume of fluid(VOF)model.The diffusion of dissolved oxygen was determined by solving the user-defined scalar(UDS)equation.Moreover,the user-defined function(UDF)was used to describe the source term in the UDS equation and determine the oxidation rate and oxidation position.The effect of the refilling speed on the molten steel exposure and dissolved oxygen content was also discussed.Increasing the refilling speed during ladle change reduced the refilling time and the exposure duration of the molten steel.However,the elevated refilling speed enlarged the slag eyes and increased the average dissolved oxygen content within the tundish,thereby exacerbating the reoxidation phenomenon.In addition,the time required for the molten steel with a high dissolved oxygen content to exit the tundish varied with the refilling speed.When the inlet speed was 3.0 m·s^(-1)during ladle change,the molten steel with a high dissolved oxygen content exited the outlet in a short period,reaching a maximum dissolved oxygen content of 0.000525wt%.Conversely,when the inlet speed was 1.8 m·s^(-1),the maximum dissolved oxygen content was 0.000382wt%.The refilling speed during the ladle change process must be appropriately decreased to minimize reoxidation effects and enhance the steel product quality. 展开更多
关键词 TUNDISH ladle change REOXIDATION multiphase flow numerical simulation
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Verification and Validation of High-Resolution Inviscid and Viscous Conical Nozzle Flows
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作者 Luciano K.Araki Rafael B.de R.Borges +1 位作者 Nicholas Dicati P.da Silva Chi-Wang Shu 《Communications on Applied Mathematics and Computation》 EI 2024年第1期533-549,共17页
Capturing elaborated flow structures and phenomena is required for well-solved numerical flows.The finite difference methods allow simple discretization of mesh and model equations.However,they need simpler meshes,e.g... Capturing elaborated flow structures and phenomena is required for well-solved numerical flows.The finite difference methods allow simple discretization of mesh and model equations.However,they need simpler meshes,e.g.,rectangular.The inverse Lax-Wendroff(ILW)procedure can handle complex geometries for rectangular meshes.High-resolution and high-order methods can capture elaborated flow structures and phenomena.They also have strong mathematical and physical backgrounds,such as positivity-preserving,jump conditions,and wave propagation concepts.We perceive an effort toward direct numerical simulation,for instance,regarding weighted essentially non-oscillatory(WENO)schemes.Thus,we propose to solve a challenging engineering application without turbulence models.We aim to verify and validate recent high-resolution and high-order methods.To check the solver accuracy,we solved vortex and Couette flows.Then,we solved inviscid and viscous nozzle flows for a conical profile.We employed the finite difference method,positivity-preserving Lax-Friedrichs splitting,high-resolution viscous terms discretization,fifth-order multi-resolution WENO,ILW,and third-order strong stability preserving Runge-Kutta.We showed the solver is high-order and captured elaborated flow structures and phenomena.One can see oblique shocks in both nozzle flows.In the viscous flow,we also captured a free-shock separation,recirculation,entrainment region,Mach disk,and the diamond-shaped pattern of nozzle flows. 展开更多
关键词 HIGH-RESOLUTION COMPRESSIBLE NAVIER-STOKES Free-shock separation Nozzle flow
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